SPECIALCOLLECTION

(ESTIMATED PUB DATE) EFFECT OF EPINEPHRINE ON THE LSD REACTION

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EFFECT OF EPINEPHRINE ON THE LSD REACTION
Many of the effects of LSD in animals and man suggest a
state of hyperactivity of the adrenergic autonomic nervous
system. Rothlin has postulated that LSD creates a central
hyperactive autonomic state. Dille and his coworkers at the
University of Washington found that phenoxybenzamine blocked
LSD-induced hyperthermia and behavioral changes in animals. The
same group found that administration of LSD two hours after
reserpine resulted in marked augmentation of the LSD hyperthermia,

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5
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U
Document Number (FOIA) /ESDN (CREST): 
00151911

LETTER TO DR ISBELL FROM R. BIRCHER (SANDOZ PHARMACEUTICALS) RE LIST OF COMPOUNDS FOR POSSIBLE SCREENING

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!Mis,
Lotti..-..,*^ or
AriAlmtio..,. Center
D!, S. Pt.b".! ic Ee41th SerTics goAp1t41
11,03 Pax 2COQ
tetxtr:44 K26ntuy
tie; 1:12..:4- to thleic yo i,t
�itr you imp.Lity ii1 tt 4 --re*r�it4 eind iitt
til.st,1:3414X/ oxtr iuti.ii crot�itcl,
hxze J!;.st roe.A.t..kti fro:a 751, 1,-".7. .!�?!,04,1. .1**AT COMP-,*=f1-4
vhIct aLri, itvailabl., Tcr,1 be x-tti terz,g15. to lot. Ira Vhteh
4. to 54.refea- t.i.243:11 viLl. it..1.40 �
4771.7t1 14'142 etnA.:7:es W ioft iobout

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4
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U
Document Number (FOIA) /ESDN (CREST): 
00151910

REPORT ON K-302

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Pe 5
Crude Fungus
Ivan
'mg
WIWig*
sallaMF
gottlEs
goAsait
, Dose-Grams
5.0
10.0
15.0
15.0
15.0
20.0
20.0
Pupil
BP
0 Relaxed,
LSD-like

KJ Subjective
Relaxed, differen
+ � 0
Giggles, arms hea
elated, no hallu-
cinations
Relaxed, legs num
drowsy,
+c. Nervous, "reefer,
lights, LSD-like
LSD-like
Placebo -
Spinach
0
0
0
0
0
0
0
0
0

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6
Original Classification: 
U
Document Number (FOIA) /ESDN (CREST): 
00151831

MEMO FOR THE RECORD RE FAX OF DOCUMENTS TITLED "CURRENT INFORMATION FROM HOFFMAN-LA ROCHE, INC., ON RO 2-3308 AS OF FEBRUARY 1960 (DELETED)" & "A STATUS SUMMARY REPORT, RESEARCH IN TOXICOLOGY DIVISION ON EFFECTS OF CS 40 30 IN ANIMALS (DELETED)" TO DR. HA

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ON RO 2-3308 AS OF FEBRUARY 196,0
15 June 1960
MEMO FOR: THE RECORD
The following two documents (T-fax copies of them) wer.e
seat to Dr. Harris Isbell on this date:
CURRENT INFORMATION FROM HOFFMAN-�LA. ROCHE, IN
A STATUS SUMMARY REPORT, RESEARCH IN TOXICOLOGY
DIVISION ON EFFECTS OF CS 40 30 in ANIMAL
a)) (3)
oir

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1
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U
Document Number (FOIA) /ESDN (CREST): 
00151775

PROGRESS REPORT ABSTRACT, TASK NO. 101-149, CONTRACT NAONR 21-62 WITHOUT ENCLOSURE

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me. Leonard:X. Libber
Read, Physeology Branch
Department of the Navy '
Office cf Naval Research
Vashingten 25, D.C.
Dear Nr. Libber:
26 October 1962
Reference: -012:2341:SZ:bbd
22 October 1962
Subjemti Progress Report Abstract, Task No. wit 1c1449,
Contract NAonr 21-62.
Tra accordance with your instructions of 22 October 1962 I am
enclosing herawiththe abstract referred to above in the fora
prescribed.
Sincerely,
Rarris Isbell, N.D.
Director
32: ra
Inclosure
2�

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1
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U
Document Number (FOIA) /ESDN (CREST): 
00151809

(ESTIMATED PUB DATE) USE OF DILUTE AQUEOUS SOLUTION (5 MCG/ML) OF A BENZIMIDAZOLE DERIVATIVE WITH POTENT MORPHINE-LIKE ACTIONS ORALLY AS A PRESUMPTIVE REINFORCING AGENT IN CONDITIONING OF DRUG-SEEKING BEHAVIOR IN THE RAT

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1.���
� ��� �-�
200 mg/kg of morphine by subcutaneous injection once daily for
several months), likewise showed no apparent aversion to the
1.4-2 solution (5-meg/rill) when water-deprived. These animals
were tested just prior to their regular daily dose or morphine,
when the acute effects of the previous day's dose (tail
rigidity, hyperactivity) were no longer apparent, and when they
were exhibiting signs of morphine-abstinence, notably, repeated
discrete twitches of the skin of the back, resembling the rapid

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PDF icon (ESTIMATED PUB DATE) USE [12855663].pdf940.52 KB
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25
Original Classification: 
U
Document Number (FOIA) /ESDN (CREST): 
00151876

INVESTIGATION OF THE KIRLIAN PHENOMENON IN INSECTICIDE TREATED PLANTS (PHOTOGRAPHIC TECHNIQUE)

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INVESTIGATION OF THE
KIRLIAN PHENOMENON
IN INSECTICIDE TREATED PLANTS
Prepared by:
31 August 1972
t.
Io
Approved for F.eo
pate 2 7 Fc.c3 ir3
INVESTIGATION OF THE KIRLIAN PHENOMENON
IN INSECTICIDE TREATED PLANTS
INTRODUCTION
The J has conducted an investigation of the
Kirlian photographic technique in an attempt to detect the presence of a
commercial soil insecticide brand Dyfonate) in various species of
plants. Dyfonate is a 5% granular organo-phosphorus soil insectide, said to be

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15
Original Classification: 
U
Document Number (FOIA) /ESDN (CREST): 
00173519

(ESTIMATED PUB DATE) BULLETIN OF THE WILLIAM C. MENNINGER - DREAM LABORATORY, NUMBER 2 - SUMMER 1969

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Bulletin of the
William C. Menninger
D EA LA
Number 2
ATORY
Olaimonioes meoicat centeR
Summer, 1969
FIRST GARDNER MURPHY FELLOWSHIPS AWARDED
Dr. Gardner Murphy, a former presi-
dent of the American Psychological Asso-
cietion and current president of the A-
merican Society for Psychical
has given the Dream Laboratory
fund to allow college students
Research,
a special
to engage
in research activities. The first stu-
dents to be awarded the Murphy Fellow-

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2
Original Classification: 
U
Document Number (FOIA) /ESDN (CREST): 
00173512

LETTER FROM HARRIS ISBELL TO NATIONAL INSTITUTES OF HEALTH RE THE EFFECT OF EPINEPHRINE ON THE LSD REACTION

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po-N,
Dipal. oF HEALTH, EDUCATION', AND .LFARE 411fublic---tealth Szrvice
NATIONAL INSTITUTES OF HEALTH�
TN RINLYINO A0001141 THE
NATIONAL !torn/nit OR 141INTAI. N221.714
AOOICTION RISItARCN CENTS*
'U.S. Pusuc Hustet Svevict HOSINTAL
P. 0. Box 2000
LEXINGTON, KtNT0C112


. -.--. a.. -1.-- . � �
-C4
10 December 1957
I am enclosing copy of a report "Effect of Epinephrine on
the LSD Reaction." You will notice that we were unable to

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1
Original Classification: 
U
Document Number (FOIA) /ESDN (CREST): 
00151912

LETTER TO NATIONAL INSTITUTE OF MENTAL HEALTH TRANSMITTING LETTER FROM GLENN ULLYOT (SMITH KLINE & FRENCH) RE FAMILIAR MATERIAL

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� )
.111.
DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
PUBLIC HEALTH SERVICE
8 May 1961
National Institute of Mental Health
Addiction Research Center
U.S. Public Health Service ,Haayital
Lexington. Kentucky
I am enclosing thermofax of a letter from Glenn E. Ullyot,
Smith Kline & French Laboratories, indicating that the material
in which you was interested is familiar to us.
Enclosure

Very sincerely you s,
/AL r
114:212nlielt74.D.
Director
as

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1
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U
Document Number (FOIA) /ESDN (CREST): 
00151791

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