January 21, 1958
Dr. Ehrrii Isbell
National Institute of Mental Health
Addiction Neeearch Center
U. S. Public Health Service Hospital
P. 0. Box 2000
Lexington, Kentucky
Dear Dr. Isbell:
40
I am very happy to hear that you yin be in Wash-t-ton soon. Ihave
set aside some time in the afternoon of February 71 so if you will stop
here at your convenience, we can go into the details of some of this work.
I have collected a considerable amount of material that may be of interest
to you.
rorPid 1 Jarmo.ry. 19>7 to I. Aievembor 1957
C:-.):77ZACT:
ANNUAL RAT 7;
COrtIMACrOR
tr., S. Public Faalth Zervice
National Institutes or Nzntal Health*
Bethesda 14* aryland
(Inquiries concernina finances and
contracts shcAlid be svnt'to this -
address, incolirizs at.out technic-4.1
work altould't:a sont to address below)
DIrcctor* NIZ4.11 Addiction Research Center--
UWE'S Nospital* Lexincton* ntucy.
PRINC/PAL INVZSTIaATal: Harris Ltbs11* M.D.
Assistanta: H. F. Fraser* .17.14n.
THf.3 AZD1CTKN LIA3ILITY OF SY4T.T1C :7.1.:35TITUTES Fr-41 CCOEINZ
(Project Description)
Request to the Office of Naval Research for Renewal of
Task No. Nn 101-149
Contract NAonr-1e.:0
1. Sarn< runt' infrirrn.tion.
since 1951 the national 1nstltut of Mental Health
Addiction P.escarch Center, U. Z. Public Health Service Hospital,
Lexington, Xy., has been carrying on a project desioned to'
develop a-izthetfe substitute for codeine which would be as
safe as codeine and as effective with respect to toxicity,
Coo
SCIEiNCE
SPECTRUM
Jo
1216 STATE STREET
POST OFFICE BOX 3003 SANTA BARBARA, CALIFORNIA 93105
TELEPHONE
(805) 963-8605
A NEW TECHNIQUE FOR STUDYING MICROORGANISMS
With differential light scattering you can learn more in minutes about
microbial morphology and physiology than others have learned in years.
Some examples are given in the accompanying Application Notes.
This technique - new to the study of microorganisms - shares some
capabilities of optical and electron microscopy. Sample preparation
MEMO FOR THE RECORD
Five gram d of compound M-247 (9 amino - 1,2, 3,4 -
tetrahydroacridine) were sent to Dr. Isbell on March 16, 1962.-
0
.���
Oa
- 3 7,C
Nstiosol Institut of Meats! Health
Addiction Itesetrcts CUM?
ILL Public Hellas Service Hospital
Lexington, Kentucky
DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
PUBLIC HEALTH SERVICE
13 November 1959
Subj,edt: 1. Progress Report Abstract, Task No. NR 101-149)
Contract NAonr-14-60,
2.. Request for Renewal of Project, July 1960
thrbugh June 1961,
3. Memorandum to Mr. Leonard M. Libber,
Head, Physiology Branch, CNR
Enclosed are copies of materials and forwarding memo-
.rt
. e.c...on �4 4
almmmlione����
from .3.11o.7.7c1 .
'7wo extractions ware performe.J; ono usirl absolute
nnd the tedOnd using .1rY skr.tecus ethanol.
1. .1...so1uto ethanol: 100 g. of driod mushrooms from the
mason collection wore macrated under 300 =1. or abs. ethnnel
in a -7artn,! blen.lor. The suspensTnn wes than stirred for 12
at room temperaturo nnd filtorcd. -his ex!..raction vas twict; .
peated. The first extrnat wac yellTs-, the !;;:i:ors vf;r:i
residue fro= those extrects was n white sold, w'th
BIBLIOGRAPHY
Ackerman, Eugene, et al, Biological Effects of High-Intensity Sound Waves,
WADC Technical Report 53-82, United States Air Force, Wright-Patterson
Air Force Base, Ohio, January 1953.
Ackerman, Eugene and F. Oda, Acoustic Absorption Coefficients of Human
Body Surfaces, Technical Documentary Report No. MRL-TD11-62-36,
Aerospace Medical Research Laboratories, Wright-Patterson Air Force
Base, Ohio, April 1962.
Air Products and Chemicals, Inc., Specialty Gases and Equipment (products
catalog) 1971.
FOIA
