FOIA
LETTER FROM HARRIS ISBELL TO NATIONAL INSTITUTE OF HEALTH RE THREE REPORTS: 1. COMPARISON OF ALD-52 AND LSD-25, 2. COMPARISON OF MLD-41 AND LSD-25, AND 3. ATTEMPTED BLOCKING OF LSD-REACTION BY PRETREATMENT WITH BOL
Document Type:
Collection:
Document Number (FOIA) /ESDN (CREST):
00151901
Release Decision:
RIPPUB
Original Classification:
U
Document Page Count:
1
Document Creation Date:
January 21, 2025
Document Release Date:
January 15, 1983
Sequence Number:
Case Number:
Publication Date:
June 25, 1957
File:
| Attachment | Size |
|---|---|
 LETTER FROM HARRIS ISBELL[12884838].pdf | 51.56 KB |
Body:
Dept:ban oc HEALTH, EDUCATION, AND ,,ELFARE � Public Health Service
4111\
IN tP.VINC AOORESS TN(
NATIONAL INSTITUT* Of MENTAL NIALTN
A oetcnon RISIARCN CiNT1R
U.S. PUOUCHEALTN StINfICS NOSPITit.
P.O. Box 2000
Winona. -
NATIONAL INSTITUTES OF HEALTH
25 June 1957
I am enclosing topics of the following reports which
think will Interest you:
I. Comparison of AID-52 and LSD-25,
2. Comparison of MLD-41 and LSD-25,
3. Attempted Blocking of LSD�React ion 5Y
Pretreatment with SQL .
As you wi 1 I note, MID Is a ps ychotom 'met c agent which,
however, is considerably less potent than LSO, whereas
AID is at least as potent as LZD. We were again
unsuccessful in obt a 'fling any significant degree of
blocking of the LSO�react Ion by pretreatment with BOL.
I am, therefore, dropping this 1 ifte of in vest igat ion
unless you feel that I should study some other dosage
schedule.
Attempted blocking of the LSD�react ion with dibenzyl ine
the adreno 1 yt To drug, is. now . In the preliminary stage.
All I can say at the moment Is that we have had no
untoward effects when mcgm./kg. of, LSD was given
two hours aft-er 1 mg./kg. of dibenzy 1 ine.
I too am sorry that 1 wI 1 I not be go i.ng to Europe, but
work schedule Is so heavy that 1 cannot .spare the
lime.
Very $ incere y,
t -
Karr is lsbe 1 , M. D.
Director
Hl:rn
Enclosures
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