MKULTRA SUBPROJECT 72

• Document Type: SPECIALCOLLECTION
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): 00319492
• Release Decision: RIPPUB
• Original Classification: U
• Document Page Count: 2
• Document Creation Date: January 23, 2025
• Document Release Date: February 14, 2000
• Publication Date: May 1, 1957

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MEMORANDUM FOR: THE RECORD
DRAF
1 May 1957
SUBJECT: MKULTRA Subproject 72
1. The'purpose of Subproject No. 72 is to initiate research
work on the neurophysiological and pharmacological effects of central
nervous system antagonists and synergists tarli=seprriif.711:v-
Itarinaa�ology,:,-,. Stanford I.Tniler�ify Schoorzof.-Mediaine7Saii��Francisdo,-7 E
(California, under the auspices o Professor._of4
Eharmacology.
2. The scope oall111111111.frogram will include the follow- C
ing:
A. To determine the neurophysiologicaland pharmacological
action upon the CNS of unknown drugs assayed against known effects
of standard drugs with CNS activity.
� B. To develop a systematic method of testing and character-
izing pharmacological agents both in terms of symptomatology pro-
duced and in terms of describing potency in producing given effects
by means of standardized and valid statistical procedures.
���
C. Act as a pharmacological consultant on problems inherent-
to TSS/CD projects at the request of TSS/CD.
D. Review of overt American pharmacological literature on
problems of specific interest to TSS/CD.
-�
3. It is expected tha from the stand- C.
point of TSS/CD interests, will be able to monitor, direct and actively
participate in this project from the eITS6.13tfrielit'ol:lyfe-dialire7:-
StatifosityeScliobrifirladi-Cine:
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4. The cost of this program is estimated at a cost of $41, 382.00
for a period of one year. To this sum must be added $1,655.28
representing a four percent service charge to theallelMillir. g
1111.111111111110111W Will function as cutout and cover
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for this grant. The cover title ort iFs project is411111111111111111111111111V 6
80111111111111111111111111111111111.111111r and is presumably being suf
ported by a research grant from
ippwagraded t:OT Deffleoffli&t-.,0.r
Mr....authority of: 11111111111h
facie-: -June 1977 41
c�-�-1.2 CL BY 1111111111.
00610100
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date:- June
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all1111111bWhe total cost of the project for a period of one year will
not exceed $43, 037.28. Charges should be made against Allotment
7-2502-10-001.
6. The Foundation has requested thuillarlizezayieszoot-6.submit
a summary accounting of monies received and to return any unexpended
grant funds at the end of the project year.
7. It was mutually agreed that documentation and accounting -
for travel expenses which are reimbursable by theaUni,v_ertity shall B
conform with the accepted practices of that institution.
8. Title to any permanent equipment purchased by funds
granted frinriiiireirditr shall be retained by them in lieu of higher E
overhead rates.
9. The requirement for a six-months' informal accounting
on the part of the principal investigator is waived.
cleared through TOP SECRET and is aware
�
aware of e true purposes of the program. He has agreed to comply
with the requirements of the Memorandum of Agreement.
Chief, Branch II
TSS/Chemical Division
APPROVED FOR OBLIGATION Approved:
OF FUNDS:
Chief, TSS/Chemical Division
Date:
� Distribution:
Original only
Attached:
Proposal
IDor, graded to:
by-authority of
Ldate� June 1977
: