DEAR ACADEMICIAN DUBININ:

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP79-00798A000700070002-2
• Release Decision: RIPPUB
• Original Classification: K
• Document Page Count: 4
• Document Creation Date: December 12, 2016
• Document Release Date: January 4, 2001
• Sequence Number: 2
• Publication Date: December 7, 1973
• Content Type: LETTER

STATINTL
NATIO'N'AL INSTITUfi OH
ENVIRONMIEN'1'AL. 1-IEAL.Ti! Ei;iENJCES
P.G. Box
F?BSFA.riCI I IRIANGLI- I?AFIt. INC. 27:041
HSS Declassification & Release Instructions on File - No referral to HSS
December 7, 19-/`3
Academician N. P. Dubinin
Academy of Sciences of the USSR
Prof_soyuznaya ul. 7 (I)
Moscow, II 7312
USSR
Dear Academician Dubinin:
Enclosed you will find a tentative program for our joint USSR-'US
Symposium on "The Potential Genetic Effects of Environmental Pollutants
an Man," which is to b-77-old in Moscow and Kiev from February 18 through
T are , 1974. I have tried to find speakers to address themselves to
the three main areas that you suggested during our meeting in Washington
on November 13--15, 1973. The titles,ar.e tentative and may be modified
somewhat by the speakers when they prepare their papers. _
I have contacted all speakers except Dr. Schull who is in Chile; if he
cannot attend, I have an alternate lined up to cover the material in this
important topic area.
We are getting the necessary clearances and visas for the US participants
to travel to Russia as well as preliminary travel arrangements. It is
possible for us to leave New York on Friday, February 15, and to arrive in
Moscow on Saturday afternoon. This would allow for a day's recuperation
from the long trip before starting the Symposium on Monday. It would be
helpful for me to have a more detailed information on the organization of
the Symposium and the institutes which you propose that we visit.. We
would also like to have a list of the Russian speakers, affiliations and
titles of their papers.
In my letter to the US participants I have asked them to prepare an abstract
of their presentation by January 11, 1974, which I will send to you
immediately so that you can prepare an abstract booklet which can be
distributed at the Symposium. I hope this will. provide sufficient time
for translation of these abstracts and publication. In line with our
discussion, I have also asked each participant to prepare a manuscript
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D1.=PARTMEN'T OF HEALTH, EDUCATION, AND WELFARE
PUE31_IC HEALTII SERVICE
NATIONAL INSTITUTES OF HEALTH
FYI
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Academician N. P. Dubinin 2
based on his presentation that can be published by you in a Russian journal
so that we can reach an even wider audience in Russia about these new and
important problems. I have asked for these manuscripts by February 1, 1974,
or at the very =Latest at the time of the Symposium. This will not only
ensure rapid publication but will also ensure accurate translation of
these papers into Russian during the Symposium.
It was a pleasure to see you again in Washington, and I do hope you had
an enjoyable and stimulating trip to California in November.
With my best wishes for the Holiday Season and New Year,
Frederick J. de Serres, Ph.D.
Chief, Environmental Mutagenesis Branch
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e:r
THE POTENTIAL GENETIC EFFECTS
OF ENVIRONMENTAL POLLUTANTS ON MAN
Moscow and Kiev, USSR
February 1.8 - March 1, 1974
I. INTRODUCTION
Environmental Mutagenesis - A New Toxicological Problem for Man,
Alexander I-Iollaender, Oak Ridge National Laboratory, Oak Ridge, Tennessee
II. DEVELOPMENT OF ASSAY SYSTEMS TO SCREEN ENVIRONMENTAL POLLUTANTS FOR
MUTAGENIC ACTIVITY
Microbial Assay Systems for Detection of Mutagenic Activity,
F. J. de Serres, NIEHS-NTH, Research Triangle Park, North Carolina
Induction of Gene Mutations in Human Cel18 in Culture, Robert DeMars,
University of Wisconsin, Madison, Wisconsin
In Vivo and In Vitro Assays for Chromosome Aberrations in Mammalian
Cells in Culture, Warren Nichols, Institute for Medical Research,
Camden, New Jersey
Mammalian Assay Systems to Detect Mutagenic Activity of Environmental
Pollutants, William Sheridan, NIEHS-NIH, Research Triangle Park,
North Carolina
The Tier System for Mutagenicity Testing, W. Gary Flamm, Food and Drug
Administration, Washington, D. C.
III. IDENTIFICATION OF 11UTAGENIC ENVIRONMENTAL POLLUTANTS
Assays of Environmental Chemical Pollutants for Mutagenic Activity
in Drosophila, Seymour Abrahamson, University of Wisconsin, Madison,
Wisconsin
Increased Somatic Mutation Rates Induced by Specific Air Pollutants
and Chemical Mutagens in Tradescantia, Arnold Sparrow, Brookhaven
National Laboratory, Upton, New York
Environmental Chemicals Known to Possess Mutagenic Activity, John Wassom,
Oak Ridge National. Laboratory, Oak Ridge, Tennessee
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IV. CONSEQUENCES OF INCREASED l'XPOS?JPE Tc3 YUTAc;E TIC EN'VTRO1`1ME?TT.,4,L CHr t7.CAL
POLLUI ANTS FOR MAN - _ _ _ _
Monitoring the Human Population to Determine the Genetic Load in Man,
Arno Motulsky, University of Washington, Seattle, Washington
Medical Implications of an Increase in the Genetic Load as a Result
of Exposure to Mutagenic Environmental Pollutants, W. J. Schull,
University of Texas, Houston, Texas
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