RECENT USSR WORK IN THE FIELD OF SYNTHETIC PHARMACEUTICALS, ANTIBIOTICS, HORMONES

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP80-00809A000600370878-7
• Release Decision: RIPPUB
• Original Classification: S
• Document Page Count: 2
• Document Creation Date: December 22, 2016
• Document Release Date: September 26, 2011
• Sequence Number: 878
• Publication Date: February 12, 1951
• Content Type: REPORT

Sanitized Copy Approved for Release 2011/09/27: CIA-RDP80-00809A000600370878-7
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CLASSIFICATION SECRET EGRET
CENTRAL INTELLIGENCE `AGENCY
INFORMATION-FROM
FOREIGN QOCUMENTS OR RADIO BROADCASTS
COUNTRY USSR
SUBJECT Scientific - Medical, new parmaceuica6
HOW
PUBLISHED
WHERE
PUBLISHED
DATE
PUBLISHED
LANGUAGE
Ca-NO.
DATE OF
INFORMATION 1951
DATE DIST./cZ Feb 1951
Monthly periodical, weekly newspaper
Moscow
Sep 1950 - 4 Jan 1951
SUPPLEMENT TO
REPORT NO.
THIS DOCUMENT COAiAINS INFORMATION AUICTINS THE NATIONAL GETS $9
OF THE UNITED STATES WITHIN THE ^ Au lS OF ESPIONAGE ACT IO
1. S. C.. SI ADD $1. AS AMENDED. ITS TRANSMISSION OR THE ISTILATION
01 Iri CONTENTS IN;.A~ ({~ Null TO AN UNAUTNORIIIO PERSON U SRO`
11SITIO ST LAS. RIP QDlrnoN Of THIS FUN IS PROHIBITED.
THIS IS UNEVALUATED INFORMATION
RECENT USSR WORK IN THE FIELD OF
SYNTHETIC PHARMACEUTICALS,ANTIBIOTICS, HORMONES
ff-i-bers in parentheses refer to appended sources.]
According to N. Polyakov, Director of the Chemicopharmaceutical Scientific
Research Institute imeni S. Ordzhonikidze, the progress made by this institute
in 1950 was marked by the following achievements, as well as other notable re-
sults.
Tibon has been successfully synthesized at the institute. This substance
is effective in the treatment of tuberculosis of the throat, of the mucous mem-
branes of the mouth, and of the bladder. It is also effective in the treatment
of recent tubercular peritonitis, empyemas, and lymphatic knots, as well recent
pulmonary tuberculosis. A method for producing Tibon industrially has been de-
veloped.
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CLASSIFICATION ''. SECRET
Sanitized Copy Approved for Release 2011/09/27: CIA-RDP80-00809A000600370878-7
The hormone division of the institute has developed methods for producing
testosterone, testosterone propionate, progesterone, and pregnene.
A new Soviet remedy, Tezan, has been obtained at the institute's labora-
tories. This remedy, which is effective in the treatment of leukopenia, is be-
ing produced in sufficient quantities to satisfy the current demand.
In addition to developing new therapeutic agents, the personnel of the in-
stitute as a whole has rendered assistance to enterprises of the Main Adminis-
tration of the Medical Industry. As a result of improvements introduced in the
course of this work into the process for the production of pyramidon the yield
of pyramidon has been raiser. by 15%.,
The following activities have`:'been planned by the institute for 1951: de-
velopment of new effective r,.medies for the treatment of malignant tumors, tuber-
culosis, and other infectious diseases; development of methods for the production
of new hypnotics and analgesics; work on substances for the therapy and 1rophylaxis
of thrombophlebites; development of continuous processes for the manufactui~- of a
number of substances, including sulfonamide drugs.(l)
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dtLhc f
S. Chesnokov, Chief Physician of the Order of Lenin Hospital imeni S. N.
Botkin at Leningrad, announced that in 1951 the infectious diseases department
of his hospital will introduce into polyclinical practice treatment of chronical
dysentery with phytoncides, treatment of acute gastro-intestinal infectious dis-
eases with synthomycin, and treatment of scarlet fever with penicillin aerosols.(2)
The Institute of Experimental Medicine of the Academy of Sciences Latvian SSR
has developed a new remedy for the treatment of tuberculosis. This remedy, which
has been tested clinically, has yielded positive results in the treatment of tuber-
culosis of the skin, and of the bones.
The Institute of Physiology of the Academy of Sciences Kazakh SSR has developed
a.remedy for the treatment of shock. On the basis of clinical results which had been
carried out, the new remedy was found to be very effective.'
A new protein blood substitute was developed by the Institute of Biochemistry
of the Academy of Sciences Ukrainian SSR. This blood substitute gave excellent.re-
sults In preliminary clinical testing.(3)
Recently, the Pharmacological Committee of the Scientific Medical Council of
the Ministry of Public Health USSR authorized the use of Dibazol, a new chemothera-
peutic agent for which methods of industrial production have been developed. The
compound in question was synthesized by Prof B. A. Foray-Koshits and Candidates of
Chemical Sciences L. S. Efros and 0. F. ainzburg. In connection with an extensive
investigation on the action of compounds which affect the nervous system (an inves-
tigation which has been carried on for a number of years at the laboratory'of the
Chair of Pharmacology, Naval Medical Academy), M. A. Rosin established that the com-
pound synthesized by Porey-Koshits increases the work capacity of healthy people and
exerts a therapeutic effect in certain diseases of the nervous system. Dibasol is
effective in restoring muscular tonus and the ability to exert muscular movements
which have been lost as a result of poliomyelitis. It is also effective in the treat-
ment of neuritis due to various causes (particularly neuritis of the facial nerve),
neuritis and polyneuritis brought about by poisoning with carbon monoxide, mercury,
or lead, and afflictions of the peripheral nervous system caused by overexertion or
overwork. More than 1,000 patients already have been treated with Dibasol and strik-
ing cures were obtained in cases where no other remedy helped. There are indications
that Dibazol is also effective in treating spastic paralyses of children and of aft-,
ereffects produced by traumatic injuries of the spine.(4)
1. N. Polyakov "Further Valuable Remedies," Meditsinskiy Rabotnik, Vol XIV, 4 Jan
1951, No 1 917), p. 1.
2. S. Chesnokov, "Introduction of Scientific Achievements Into Medical Practice,"
ibid., p. 1.
3. V. P, Kiriohenko, "7th Session on the Coordination of scientific Activities of
the Academies of Sciences of Union Republics," Vestnik N SSSR, Vol XX, No 9,
Sep 1950, pp 36-37.
4. Prof N. Lazarev. "New Method of Treating Diseases of the Nervous system,"
Medit inakiy R k, Vol XX, 4 Jan 1951, No 1 (917), p 4.
SECRET
Sanitized Copy Approved for Release 2011/09/27: CIA-RDP80-00809A000600370878-7