INOCULATIONS AGAINST CUTANEOUS LEISHMANIASIS

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP80-00809A000600390438-3
• Release Decision: RIPPUB
• Original Classification: S
• Document Page Count: 2
• Document Creation Date: December 22, 2016
• Document Release Date: October 19, 2011
• Sequence Number: 438
• Publication Date: May 29, 1951
• Content Type: REPORT

Sanitized Copy Approved for Release 2011/10/19: CIA-RDP80-00809A000600390438-3
CLASSIFICATION SECRET SOCKET
CENTRAL INTELLIGENCE AGENCY
INFORMATION FROM
FOREIGN DOCUMENTS OR RADIO BROADCASTS
SUBJECT
HOW
PUBLISHED
WHERE
PUBLISHED
DATE
PUBLISHED
LANGUAGE
Scienti" c - Medical; cutaneous leishmaniasis
Daily newspaper
Ashkhabad
Turkmenskayg Iskra.
REPORT
CD NO.
DATE OF
DATE DIST..4
SUPPLEMENT YO
REPORT NO.
INOCULATIONS AGAINST CUTANEOUS LEISHMANIASIS
S. Bobrov, Scientific Assoc
Turkmen Dermato-Venerological Inst
A. Kuznetsova, Scientific Assoc
Turkmen Inst of Epidemiology and'Microbiology
Sanitized Copy Approved for Release 2011/10/19: CIA-RDP80-00809A000600390438-3
The incidence of cutaneous leishmaniasis is especially high in Central
Asia and in certain parts of the Transcaucasus. In some regions it assumes epi-
demic proportions..
Systematic study of cutaneous leishmaniasis in the Soviet period was be-
gun in. Merva by Khlodukin and was continued by I, I. Gitel'zon who, in 1933,
wrote a monograph in which he reviewed all prior data on this infection and in-
cluded the latest developments on it.
During the past decade considerable progress was made in the study of the
treatment, immunity, slid methods of controlling cutaneous leishmaniasis. The
results of successful scientific search conducted by Kozhevnikov, Dobrotvor-
skaya, and Latyshev, scientific associates at the Turkmen Scientific Research
Jic7 Dermato-Venerological Institute, were published in a monograph entitled,
Research on Cutaneous Leishmaniasis.
The problem of acquired immunity against cutaneous.leishmaniasis was in-
vestigated by I. I. Gitel'zon in 1929, and in 1930 by Tikhomirov who used live
cultures of leishmaaiasis to inoculate 54 people. The refinements. of Tikhomirov's
method were subsequently worked out by Lavrov, Dybovskaya, and Sokolova at the
Turkmen Dermato=Venerological Iistitute.
50X1-HUM
Numerous'tests conducted at this institute revealed that inoculation
against this infection on covered portions of the skin (shoulder and hip), re-
sulted in a mild form of the infection and served the essential purpose of pre-
venting the spread of ulcers to, the face and other uncovered portions of the
skin.
 Sanitized Copy Approved for Release 2011/10/19: CIA-RDP80-00809A000600390438-3
SECRET
The producti9n or the leisbmaniasis vaccine was far below the amount re-
quired for large-scale inoculation of the population against this infection, and
this shortage was further accentuated by the influx of large numbers of people
in connection with the reconstruction of Ashkhabad probably following the earth-
quake in 194,8], and the construction of the Main Turkmen Canal. Therefore, at
present the Turkmen Institute of Epidemiology and Microbiology is attempting,to.
improve the method of preparing a live leishmaniasis vaccine on a large scale.
Kuznetsova, co-author of this article, studied and worked out a me';hci for
preparing this vaccine in large quantities, and in a form capable of being ship-
ped without affecting its inoculative properties. Vaccines against cutaneous
leishmaniasis, prepared by Kuznetsova, are being tested on a large scale by the
Turkmen Dermato-Venerological Institute. The results will be applied to general
inoculations.
Inoculations made in 1950 with the vaccine developed.by the Institute of
Epidemiology and Microbiology showed this vaccine to be very effective; no
serious skin damage at inoculated areas resulted.
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Sanitized Copy Approved for Release 2011/10/19: CIA-RDP80-00809A000600390438-3