NEW USSR WORK ON ISOLATION OF SPECIFIC PROTEIN OF MALIGNENT TUMORS

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP80-00809A000700200146-6
• Release Decision: RIPPUB
• Original Classification: C
• Document Page Count: 1
• Document Creation Date: December 22, 2016
• Document Release Date: August 31, 2011
• Sequence Number: 146
• Publication Date: October 4, 1954
• Content Type: REPORT

Sanitized Copy Approved for Release 2011/08/31: CIA-RDP80-00809A000700200146-6
COUNTRY USSR
SUBJECT Scientific - Medicine, immunology, cancer
LANGUAGE
HOW
PUBLISHED Semiweekly newspaper
WHERE
PUBLISHED Moscow
DATE
PUBLISHED 23 Jul 1954
DATE DIST. I Oct 1954
SUPPLEMENT TO
REPORT NO.
THIS IS UNEVALUATED INFORMATION
Mrdlt~inFkiy Robot ik~ No 59 (1233), P 4, columns 5, 6
NEW USSR WORK ON ISOLATION OF SPECIFIC PROTEIN OF MALIGNANT TUMORS
The personnel of the Laborator
of
y
mental medicine, -
mental [Institute of Experi-
, Academy of Medical Sciences USSR), the head of which is Prof
V. S. Gostev, is engaged at present in work on the separation of various
fractions of the protein of human tumor tissue and the isolation of the spe-
cific protein of cancer tumors in a purified state.
Research in this field became possible after Scientific Associate A. K.
Saakov had obtained a reagent for cancer tissue in the form of the so-called
monospecific anticancer serum which reacts with cancer proteins exclusively
and does not react in the slightest degree with normal proteins.
Successful work on this subject is being carried out by V. I. Sachkov,
Candidate of Medical Sciences. He obtained from human tumor tissue a protein
fraction which is 20 times more active toward anticancer serum than the ini-
tial extract from the same tissue. Sachkov achieved this result by salting
out with ammonium sulfate solutions of different concentrations the protein
fractions contained in an extract of tumor tissue. He modified the usual
procedure of salting out 171 immersing in the beaker containing the extract of
tumor tissue a rotating cellophane cup filled with a saturated ammonium sul-
fate solution. The proteins which are gradually precipitated as the-concen-
tration of ammonium sulfate increases in the beaker represent different frac-
tions of human protein tissue. Each of these fractions is investigated
chemically in a precise manner. The fraction which has the strongest capac-
ity for combining with the monospecific anticancer serum contains the great-
ests amount of specific cancer protein.
At present, the workers at the laboratory are attempting to isolate
the cancer protein in a pure state to subject it to further study.
STATE
ARMY
CLASSIFICATION C O N F I D E N T I A L
NAVY NSRB DISTRIBUTION
17
Sanitized Copy Approved for Release 2011/08/31 : CIA-RDP80-00809A000700200146-6
CLASSIFICATION 0-N_F_1
-D-a-i1-T-I-A_L
CENTRAL INTELLIGENCE AGENCY
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