PENICILLIN FACTORY AT PRAGUE-ROZTOKY

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP82-00457R008000420011-9
• Release Decision: RIPPUB
• Original Classification: S
• Document Page Count: 2
• Document Creation Date: December 16, 2016
• Document Release Date: November 3, 2003
• Sequence Number: 11
• Publication Date: July 10, 1951
• Content Type: REPORT

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Approved For Release 20041 1/7R ? CIA-RINDR9-M457Roflantit1420 11-9 25X1
CLASSIFICATION Q,,ligRagr
CENTRAL IVTELLIGENCE AGENCY REPORT NO.
1NFOR ATBON REPORT CD NO.
COUNTRY Czechoslovakia
SUEJECT Penicillin Factory at Prague-Roztoky
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25X1DATE DISTR. 10 July 1951
NO, OF PAGES 2
DO NOT CIRCULATE
NO. OF ENCLS.
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SUPPLEMENT TO
REPORT NO.
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THIS IS UNEVALUATED INFORMATION
In 19469 a penicillin factory was constructed on the eastern edge of the city
of Hostiwar (051/1. 88) located about 20 km from Prague. The equipment for
penicillin production which was supplied by IRMA, was only held in storage
at the plant far two years. In 1948, trial production of small. -quantities of
liquid penicillixt was initiated at the Hostiwar plant. In the maker of 1949R
penicillin production was discontinued and the equipment of the plant was moved
to Pragle-Rootoky. Thus the plant in Roztoky became the sole source of
penicillin production in the CSR. Dr. Milos Herold? preflously in charge of
the Hostiwar plant, was transferred to RoAoky as director of the new factory.
2,, Product Lou at the Rottoky penicillin plant began in the latter part of 1949.
Only one kind of penicillin is produced there,. i?e., potassium snit penicillin
fAalium3alzpenlcillin) in liquid form_ The production is sufficient to meet
all CM dozzab,,46 for this type of penicillin, but all other for a penimillin
mast be imported, most of them coming from Holland.
The ini.Usl output of the RiaPtoky plant after the initiatim of production
there in 1949 was 2?000 vials of 200,000 units each per week. Later? the
quantity of production was greatly increased, so that in the summer of 1950
the pla3t reached a production of about 10,000 vials containing 200,000 units
each in lOce and also an unknotin number of vials containing 2000000 in 5co.
It is btlieved that the volume of production has in the meanwhile been further
increased ,. Tests by the Health Institute have shown that the 5ce vials are
frequemly deficient in units contained, so Czech hospitals customarily add
50 peremt to the dosage when using these vials. The quality of penicillin
produced at Rontokyi, while recognized as good, does not meet all the standards
of puriy, and is even colored.
The penLcillin produced at Roztoky has a. sensitivity of 0.02 to 0.04 I.E. per
cc against staphylococci,, i.e., 0.02 to 9?04 units in lec are lethal for ice
of stap%rylococci. After tests conducted at the State Health Institute it
was established that this penicillin is effective against the following
bacteria staphilococcus aureusg streptococcus pyogenes g strept.viridans,
strept. anhemolyticusg pneumococcus, bacillus anthracisig Corynebacterium
diphthala.es, actinomyces Neisseria, Gonorrhg, meningitis g catarrhalis (sic)F
Spirochnetag. Clostridium welchii, Clostridium septicurt4 Clostridium tetaniD
Clostridium oedervitiens.
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CENTRAL INTELL/GENCE AGENCY
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5. In Prague there is only one military hospital besides the military dispensaries,
This hospital and the dispensaries obtain as much penicillin as they require.
With regard to the hospital am' particularly difficult cases which require
specialized treatment are generally transferred to one of the civilian clinics
for treatment. A new department which is termed an *Infektionsabtellungfts,
has been established In the Prague Military Hospital. In 1946 or 1947? four
Soviet professors visited this department of the Military Hospital to give the
personnel instructions in epidemic diseases CMasseninfektionen) such as
cholera and typhus. One of these professors also spent about six months in
the hospital at Pardubice.
6. The civilian hospital in Hradec Kralove
20 million units of penicillin per week
production since then this hospital now
quantity.
(Keeniggraetz ?. 0 51/G 71) obtained
in January 1950. Witlithe increased
receives a considerably gr ter
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