SCIENTIFIC ABSTRACT ALIKHANYAN, S. I. - ALIKHOVA, T. N.

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17(400) AUTHORS: Alikhanyan, S. I., Klepikova, F. S., SOV/20-125-3-51/63 __ _ _ nd Z 1Tnj Be Z.9 Garina, K. P.9 Zhdanova, N. I. TITLE: Characteristics of the Induced Mutation Process in Actinomycetes - the Producers of Antibiotics (Osobennosti indutairovannogo mutatsionnogo protsessa u aktinomitsetov - produtsentov ant,ibiotikov) PERIODICALi Doklady Akademii, nauk SSSRO 1959, Vol 125, Nr 3~ pp 643-645 (USSR) ABSTRACT: Not only different species but also closely related strains of the same microbe species may differ with respect to their sensitivity and the frequency of the induced mutation (Refs2-5). As a result of their investigations of actinomycetes the authors were-able to-provide-a comparative analysis of the variability with respect to.the production of antibiotics in strains of the same and of-different species. The producer of streptomycin, albomycin, oxytetracycline and vitamin B 12 was concerned. The strains of the albomycin producer were irradiated Card 1/4 with X-rays with an intensity of 399 r/see and a dose of Characteristics of the Induced Mutation Process in SOV/20-125-3-51/63 Actinomycetes - the Produce:;9 of Antibiotics 20 to 640 kr. A bactericidal lamp BUV-30 served for the ultra- violet irradiation (wave length 2537.1). of the producer of oxytetracyclia6-The irradiation intensity amotmted to 100 erg/.~ sec at a distance of 15 cm. The sl)ores of the producer of vitamin B,,, were treated with ethylenimine (dilut-':'on 1:7000). Figure 1 shows data concerning the frequency of formation of the plus and minus variants of Act. subtropious (albomycin producer). An already earlier described regalarity (Ref 6) can be Been therefrom: to begin with the number.of both plus and minus variants increases with an intensification of the dose. As soon as the curves have reached a certain levelp a decrease occurs.. In both cases (strains Nr 39 and 738) the highest amount of plus variants is achieved at lower doses than the maximum of the minus variants. Both strains vary considerably with respect to the ratio between plus and minus variants. It was proved that the type of varia:bility differs between the highly active "cultivated" strains and those of the wild type (with low activity). Figure 2 shows the curves of variability with Card 2/4 respect to the frequency of plus and minus variants in highly Characteristics of the Indu.:ed Mutation Process in SOV/20-125-3-51/63 Actin'omycetes - the Produce:rs of Antibiotics active strainig of the producers nf streptomycin and oxytetracycline (Act..globisporus streptomycini, strailnNr 66 and Act. rimotius, strain Nr 293 respectively). The former was preserved alone by several times selecting it under the effect of X-rays and ultraviolet rays, the latter under ultraviolet irradiation. Figure 2 shows that the results are oimilar to those obtained for the active strain Act. subtropicus Nr 738P i.e. the frequenoy of the minus variants increases that of the plus variants considerably. In the case of the little active-, not several times selected strain H-6 of Act. olivacous (the producer of vitamin B12) the frequency of the plus variants was much higher than that of the minus variants under the effect of eth-.rlenimine, just like with the little active strain Nr 39 of Act. subtropicus (Fig 3). Thus, it was proved that in strains of va:rious species in many cases a similarity is possible with respect to the type of induced variability of the characteristio feature of the formation of an antibiotiop whereas strains of one and the same species may highly differ Card 3/4 in this respeot. This regularity appears also in the case when Oharacteristics of the Induced Mutation Process in SOV/20-125-3-51/63 Actinomycetes - the Froducors of Antibiotics different strains are subjected to the effect of completely different mui;ageneous factors (see above). Pinallyq the authors endeavor to explain these facts. There are 3 figures and 9 references, 3 of which are Soviet. ASSOCIATIONt Vaesoyuznyy itauchno-isaledovatellskiy institut antibiotikov (All-Vnion Sclientific Research Institute of Antibiotics) NTEDt November ig, 1958, by I. I. Shmallgauzen, Academician SUBMI -TTED& November 19, 1956 Card 4/4 17 (1) AUTHORS: Golidat, S. Yu.p Alikhanyan, S. I. SOV/20-125-5-49/61 TITLE: The Effect of the Combined Application of Ultraviolet and X-Rays Upon the Mutagenic Process in Streptomyces aureofaciens LS-B16 (Vliyarti-ye kombini-rovannogo deystviya ul'trafioletovykh i rentgonovski,kh luohey na mutatsionnyy protse8s u Streptomyoes aureofaciene LS-B16) PERIODICAL: Doklady Akadendi nauk SSSR, 1959, Vol 125, Nr 5, PP 1134-1136 (USSR) ABSTRACT: The mutagenio effectiveness of the rays mentioned in the title can be modified by several additional factors and conditions which influence the sensitivity of the cells to the radiant energy (Refs 1-5 et al). In,this connection it was interesting to clarify the effectiveness of the interaction between- these: -two.kinds. of rays and to determine whether irradiation with one.of these factors influences the mutagenic effect of the other one. The fungus mentioned in. the title, a biomycine producer which had been obtained by the authors due the combined application of the two aforementioned kinds of rays to the spores of the phylum LS-B536, was used for this Card 1/4 purpose. Ultraviolet rays were produced by two bactericide The Effect of the Combinpi ~P-licp.tion of 111trn,violot nnd X-111--vs Vif~ ~.ut-gcnic Flrocfs- inStreptomycesmiw1kciewLS-816 lamps 3uv-lj. rmri prodii-:d by the tube 0' V apparatus IRT '-7 tl~ ohorl f o.-f7l dis 4.,-.nce. The i,-_ I-a r ir.t -).'I 0u" .1!1 1. !o furnn " i th e(jwd 1,~l I.!"- 7 ni"I vii~o vernrl. In cithor Llhc one !~iyl, y tlv~ o'Wr houro. -0 ti-.- sim!vnision Yms otore., -it -il- rcs,ultz; are piven in tn'bles 1 PnO 2. TaIlle (%Nact of t~p tv;o 1:inin or rali:--idon -1~, c!,ch tura cor.-3.idorobly leas intonse than t*1~7. CrIr1:1,A-i"re Offen". The act!tvmco of Jirralir'ion influ(!n,---~ c(,n:,,i-d-ra!,1.-.- Via viability of the of th,,4 flin7;-- rcnti-n,,~J in Vie title. The L)ffe(-' vv-;s -i,~,c', i.!i i',vi crri.- of cco~%binnd violot-v!y-, ---) -if,hout L!It,-1,v-1. intorvi-11- of I or 2 hours i.h.-.n in tiv., ca3a of ?n 1nv-.---:~, r:-Ii.-~nce of irvviiation. Thuo, rr,,:-, nii,i:(--~ -!(,.rtr-'ln -~,zt-.-~n'. the lothal all'f'oct 0--f tl,p cp-~e of 1-1 4 1 !V, -rn-r4,ily results. Tn this (..q.,10 W,f~, lorrrs~r Card 2/4 J. The Effect of the Combinpd ApplIcati,,n o" M'traviolet and X-Rays Upon the Proco:~-~ inStreptomwomareobaknaLS-B16 Table 2 nhowo the eff'.?Ot tt!'! Mlut.ntions weri~ conriiderabl:r more frwiuent (:f irraaiation X-rnys --k ultraviolet rn,!Z3 Vann A t" of -r,, inverse neqiience. The protreatment vtlth ult--vj.~,I el: r~--'y.'3 compensated to u certain -content the subscauenL irr.,.:Ii-P.I.Ion wit!i :,I,-rq.v3. 11,,o nutntions (7. wis ohtnine~ r1i ti: nn between the imlivi.-4ur! irraoiatio-17: lfrl- of nutations wn-3 obtritnoi-i by Pn invor:~,_- 9-111 :1 intf'.Irval of 3 houro, it howevor, Oir: combinntion. ~'he rc-sizltn obtainerl rirn to b~, provisional. There figur.,~:,, 2 trIbloo, 1 of which is Sovi(-.It. A 3SOCIATION: Vsesomznyy (All-Union Scicntific Restorch inztitutr! i b C-!trd 3/4 ALIKHANYpj_,R.j_._ Use of physical and chemical factors in the selection of micro- organisms. Triudy Inst. mikrobiol. no.10:46-58 161. (MIRA 14:7) (INDUSTRIAL MICROBIOLOGY) (VARIATI01t (BIOLOGY)) !~~ . i --, --, --.1, - :-~ '. ,~ :. ~ KAMENEVA, S.V.; ALIKIIANYA4, S.I. Studying the comparative mutability of some loci in Actinomyces ,olivaceous strains produced by genetic transfers. Radiobiologiia, 1 no.5:725-730 161. (MIRA 14:n) 1. Institut energii imeni I.V.Kurchatova AN SSSR, Moskva. (ACTINOMYCES) (RADIATION-PHISIOLOGICAL EFFECT) (VARIATION (BIOLOGY)) YEROKHINA, L.I.; ALIKHANYAN, S.I. Use of'visible light in studying the kinetics of mutagenesis. Radiobiologiia I no.5:792-795 161. (MIRA 14:.u) 1. Institut(atomnoy energii imeni, I.V.Kurchatova AN SSSR, Moskva. ULTRAVIOLET LIGHT-PHYSIOLOGICAL EFFECT) (VARIATION (BIOLOGY)) ALIMQffmI-s-.T-.j, prof. C038mi0al mutapnevie* Zhur,VKHO 6 no*3.*285-292 161. (MM 14t6) (Variation (Biology)) (Bioohanietry) IMIL.1141.1 S.Z.;- hUBYSHKINA, T.A.;_:ALIKHAN`Wl.. S-I. Use of Act. rimosus mitants for the itwy of oxytetracyaine biosynthosis. Antibiotiki 6 no.7;623-629 Jl 161. (MIRA 15:6) 1. Institut atomnoy emrgii AN SSSR imeni J,V. Kurchatava. (CIMTRACYCLIIIE) (ACTINOIlYCES) ALIKHOUN, S.I.; GARINA, K.F.; ZHDAROVA, N.I.; VIjWDIIiiOV, A.V. Selection of a strain of Act. antibioticus for %,he production of oleandom,yoin. Antibiotiki 6 no.10:867-871 0 161. (MIIA 14:12) 1. Vsesoyu;nyy nauchni>-iasledovatel'skiy institut antibiotikov. (OLEAND011-MCIN) (ACTINOMYCES) AL.LaWMIJI, S.I.; 1,10.'WZOVA, Yo.S.; VLSLLOVA, 6.1. Comparative study of the variability in antibiotic syntliesi.,j of various strains of Act. streptomycini under the influence of ultraviolet rays and ethyleneimine. Antibiotiki 6 no.12:1055,1058 D 161. 1.5-.,2) 1. Vsesoyuznyy nauchno-tasledovatel'skiy institut antibiotikoNr, I'ACTIN014YCW) (MMIVIOUT AYS-PUSIOL-WICAL I.FF."UT) (E;TIIYIX- NDIIIIE) ALIKIUMN S.I. BORISOVA, L.N. Recombination of Actinomyces aureofaciens. Mikrobiologiia. 30 no.2s214-220 Vh"p 161, (KIPA 14t6) 1. Vaesoyuzny-.f nauchno-issledovatellskiy institut antibiotikov, Moskva. (.STREPTOMYCES) ALIKMNYAN, S.I. I I Genetic research in Ozechoslavakia. Biul. MOIP. O;W. blol. 66 ;1o-4: 140-143 JI-Ag t61. (GEECHOSLOVAKLk--GENETICS) (MIM 3.49 7) -ALIKELOMp S.I.; MINDLIN, S.Z.; ZAYTSEVAy Z.M.; ORLOVA, N.V. Production of inactive matants of Actinomyces rimosus aj3d formation of the antibiotic during their joint cultivation. Dokl. AN SUR 136 no.21468-471 161, (MIRA 14:1) I.Predstavleno, akademikom M~MaShemyakinym. (ACTINOWCES) (TURAMYCIN) ZAOTSEVA, Z.M.; XINDLINp S.Z.; ALI -S-T~- ,A~IKRANUN-, Terramycin synthesis in joint cultures of inactive =tants of Actinomyces rimosus. DAL AN SSSR 136 no. 3:714-7.17 Ja 161. (11M 14:2) 1. Predstavleno akadqmikom V.N. Shaposhnikovym. (ITIRRAMYCIN) (ACTINEMYCES) ERGELIGARDT, V.A., akademik, glav. red.; KUZIN, A.H.p zam. glav., red.; HUDIN; N.I., rod.; ALI ANYAN, ".rdoktor bicl. natk, red.; SHAPIROp V.I., kand. biol. naukp red.; KOCISREZHIM4, Veflop kand. biol. nauks red.; ARSW OYEVA, M.A., red. lzd-va; FRUSAKOVAp T.Asp tekhn. red. [Radiation genstios] Radiotsionnaia genetika; sbornik rabot. Mo- skvap Izd-vo Akad. nauk SSSRp 1962. 367 p. (MIRA 15:2) 1. Akademiye, nauk SSSR. Otdeleniye biologicheaki)th nauk. 2. Chlen- korreopondent AN SSSR (for Kuzino Nuzhdin). 3. Institut. biologiche- skoy fiziki AN S33R. Moskvm (for Kuzin)o (GENETICS) (lUDIATION-PIMSIOLOGICAL EFFECT) ;LUT11ORS: Alikhanyan, S. I., Yerokhinal ---L ----------------- T112LL: Peculiarities of the induced organisms S/.747/62/000/000/022/02 D243/D307 I L. I. ard Lyubinskayaj 3.1 ! mutation process in micro-, SOURCE: Radiatsionnaya genetika; sbornik rabot, Otd. biol. nauk AN SSSR. Moscow, Izd-vo AN SSSR, 1962, 319-332 1. TPXT: The authors wishc(i to study the mechanism of mutation forma- tion in actinomycote3, a~:tcr irradiation with uv, and the effect of visible li-lit on tho reactivation of cells inactivated by ultravi- olet. Aqueous spore suspensions of H-6 Act. olivaceous received do- ses of 250 - 5,000 er.-/=12 see from a 9Y8-4S(BUV-15) bact ricidal lamp giving resonance ra6iatio with a wavelength of 2537 1. Visible lic,lit, was between 3300 - 3600 K. The constant factor for inactiva- tion was 0.2, for mutagenesis 0.5. Visible light removed the cell inactivation, effect and mutagenic effects caused by both high and low doses of uv. The ext(;,nt of reactivation differs from that of f::-equency reduction and the processes involved seem to be indepen- Card 1/3 3/74 62/000/000/022/025 Peculiarities of the ... D243YD307 dent. To determine the dooe of vioible light required for maximum reactivation and removal of the mutagenic effect, spores of H-6.Act.' olivaccous were immodiately after radiation subjected to photoreac- tivation for 1/2, 1, 2, 4 and 6 hours. Kutation formation %bras stu- (lied in the'biochemical matant No. 74 Act. olivaceous ovel- a 7-hr. j)-.~.riod. It was found that up to 50',o' only of irradiated upores were reactivated by visiule li4~ht, and that when spore survival was in- C creased 15,000 times, only 75',4", of uv-inclined mutations were re- V moved. Two hours were vcq~tired for visible light to extert its maxi- j.ium effect on botli procesoes. Mutation 2ormation is a drolonged pracess and may vary at each locus in relation to the degree and na- -,;ure of the initial daimuge. Some (intutantaneous) mutations are ne- ver r,~L;tored; They drobably result from very severe damage to a lo- cus, occurring durin-, ii-rc.diation. The problem of changing radio- fjonsitivit"y after redeated. doses of radiation was also considered by .-OportJAIrr eXdOr1M;.:ntt3 carried out while seeking new Actinomycete .,;T.rains with improved antibiotic activity. The strains investigated wexe Act. subtropicus, rimosus and spheroides. The hypothesis that a tiOn LXiots between the ability to manufacture anti- _,.iegativc correla C:a:rd 2/3 8/747/62/000/000/022/025 Pec.zliuri ties of ille D243/D307 biotics and radioinsensitivity was not confirmed. The organisms did nat b(~comc accustomed to the effect of radiation, either in respoct of' t-he inactivation or the genetic effect. The gradual rise in aenBi- tivity iu tho result of an 'accumulation' of the lethal genetic ef- fect in a sQries of irradiated cell generations, There are 7 figures and 5 tables. Card 3/3 42698 3/747/62/000/000/023/025 .:~:T I'D D243/D307 "LuThOR-3: Alikhanyan, j. 1. and Kameneva, S. V. ,21TLE'. The genetic effect o-L ' radiation in microorganisms with various reorganizations of nuclear structures &)-U'-""'CE: Hadiatsionnaya genetika; sbornik rabot. Otd. biol. nauk AN 3103R. Hoscow, Izd-vo AN SSSR, 1962, 333-345 .LEM: 'The influence of the genotype of an irradiated organism on the effects of radiation was investigated by considering the influ- ezice of the genetic effect of irradiation-with changing number of nuclear ~itructures in the cell and the effect of grene position in moulds of the 2enicillium type, whose so-called parai3exual cycle e~iablcs a-table, diploid utrainu to be obtained, The8e moulds are considered to have curtain advantages over the plants and microor- tganisms hitherto used in such studies. Two diploid groups of mutant -trains of P. chrysagenum were uaed: di,iloid family 58/66 consisted 0 of two initial hadloidstIP and HA-3 (NG and NA-3), diploid 48/66 -ai-id a diploid recombinant P-_2 (R-2); diploid family 16/66 consisted Card 1/3 _S/74 62/OJO/000/023/025 The genetic offect ... D243y,)307 of two initial had'Oid L;-rains (11 a and NA-3), didloid 16/66 and a h.aploid recombinant 11-1. "L',-e number of morphological changes, e.g. colony si-ze, and the total, number of mutant and recombined' forms in each strain were comoa:7ed after irradiation with loses of uv // -2 (from 250 - 8,000 erg nmi ) and of x rays (5,000 to 160,000 r). An- tibictic activity was determined in diploid 16/66 after doses of 2,OJO and 4,000 er 'mm2. The numucr of morpholo.-ical changes was 9/ L3, much L'reater in diploids -;han in haploids aftur both uv and x ray irradiation. The muiability curves for uv irradiation were similar in both forms, with a j)eak at 4,000 erg/mm2, whilst for x ray irra- diation the diploid curve peak lay at 40,000 r, and the haploid at :0 d 000 r. Otudy of Lntibiotic activity showed a greater number of ,.Ius-variants in diploids at low doses. The-se differences in.res- ,)cnse are considered to b~, due to the diploid's greater capacity for crossov,~rs. '.~he influonce of the -renome on the response of an 1;-.dividual gone to radiat-,.on waij studied in two double auxotrophic ;;iutants obtained f-Crom biochemical mutants of Actinomycetes oliva- CODUS b~ the authors' transduction method (Dokl. AN SSSR9 1960, 5, no. 132 . uv was used in doses of 250, 500, 750 and 1000 erg/mm2, Card 2/3 S/747/62/000/000/023/025 '21jo, ren(jtic effect ... D243/D307 and x rayu in 5 x 103, 10 1~ , 1.5 x 104 and 2 x 104 r doses. The ef- uct 6-17 genome on the reverse mutation at two loci was studied. At One locus, no mutations were found after uv irradiation in strain 80; M the genotypically very similar strain 5, which differs in one nevily inLroduced gone only, a mutation rate'of several tenths per 103 E3urviving spores was measurpd; in strain 199 which differgd sub- i3tantially from strain 80,, the mutation rate reached 8 pei 10 sur- viving bpores at 1000 erg/mm2. After irradiation with x rays at the same locus, in utrain 80 no mutationu were observedq in strain 5 ~7 per 109 surviving spores tit 20,000 r, while in strain 19 the frequen- cy declined again. Investigation of the second locus revealed a sim- ilar picture. It is concluded that the effect of genotype on post- irradiation mutation behavior at a locus and the specificity of be- havior at that locus are clearly shown. There are 8 figures and 2i tables. Ca:,"d 3/3 LURIYE, L.M.; ALIKH&NYAN, S.I. Formation of penicillLn through uniaterrupted fedding of carbohydrates into fomentation media. Antibiotiki 7 no.1:2.1-16 A I &'iA 15t2) 1. Vsesoyu *nauchno-issledovatollskiy i atitut antibiotikov. 'UMNICILLDI) (GAUOHMRATES3 ALIKHANYAN, S.I.; CHEIMOSVITOVA, V.I.; LYUBINSKAYA, S.I. Some characteristica of the selection of hiChly active strains of penicillin-produaing organisms. Antibiotiki 7 no,61491-495 Je 162. (MA 15:5) 1. Vsesoyuznyy naualmo-isoledovatellskiy institut antibiotik-ov. (PENICILLIUM) . ALIKHAN~YANS~I.J- MIlbLIN, `.Z.; SUKHODOLETS, V.V.; KRYLOV, V.N. Some current probleras in the genetics of micro-organisinB. Antibiotiki 7 no.90141-852 S 162. (MIRA 15:12) 1. Institut, atomnoy energii imeni Kurohatova AN SSSR. (G'.WTICS) (MIGROBIOIDGY) I not, i't V.."r, -1 V~ col tdc" to C L 4un r vi -W u f I with worr Of ;iI.,: n-J noij* ALIKHANYAN, S.I.; TETERYATNIKO A,F. Obtaining streptm~yqin-produoing variants under the influence of actinophages of *zero" mutants of the IS-1 strain of Act. streptomycini. I-likrobiologiia 31 no.1:54-60 ja-r, 162. (NIRA 15:3) 1. Vsesoyurxqy muchno-issledovateliskiy imtitut antibiotikov. (ACTIMMYCES) (13ACTERIOPHAGE) (STREPMMIN) MINDLIN, S.Z.; ALIKHAN-YAN, S.I.; MURAVIYEVAP L.I. Studying the mech".sim of recombination in Actinomyces rizosus. Mlkrobiologiia 31 no.3-."3-"8 Yq-Je 162. (MIRA 15:12) 1. Institut atomnoy-energii imeni I.V.Kurchatova AN SSSR. (ACHNOMYCES) (BOTANY-VARIATION) ALIKHANYAN., S.I. Induced mutagenesis in the selection of micro-organisms. Izv.AN SSSR.Ser.biol.27 no.4:544-575 Jl-Ag 162. (KRA 15:9) 1. Kurchatov Institute of Atomic Ener . MOSCOW. (ANTIBIOTICS) (VARIATION fBIOLOGY)) 7AAYTSEVA, Z.M.; ALIKHAIMM, SJ. Production and properties of new teracyclines. Antibiotiki 13 no.6'.551-556 Je'63 (MIRA 17:3) , ~j ?;.,, ~' . : '. . ~17 . ; I I' -, ? ;' ~.' - ~A . ~L ~ '4~.. - . . MKRTUMYAN, N. M. , and _ALIEMIYAN, _ S. I - H Induced Mutations in Extraci!llular Actinophages." report submitted for the 11th Intl. Congress of Genetics, The Hague, Netherlands, 2-10 Sep 63 ALIKHANYAN S and OGANESYAN, M., "New Derivatives of 9-chloro- ethyl- amine as Active Mutagenic Factors." report qubdlitted for the 11th Intl. Congress of Genetics, The Hague, Netherlands, 2-10 Sep 63. KITTIFOVA, 0'.1. C=parative otudies on cf vrir-~nus mu,,,gm4c racLors on Act.lnonlyoo.~. o-obtropLeis culturev. :Antib,lot~ll.! 8 n0.9:777-782 , 163. 11 17:11) 1. n-iii~iiiio.-i-.g-:,-Iedova*r.11.9i~iy institi;t antiblotLkov. YEROMINA, L. I.; ALIKHANYAN, S. tv The production of mutants of actinomyces rimosus., synthetizing substances different from oxytetracycline." report submitted for Antibiabics Cong, Prague., 15-19 jun 64. Inst A-!;omic Energy im I. V. Kurchatov, Moscow. C.. T A I IJUI - I I- - - - "Gem.-tic control of metabolic processes." report submitted for Cong on Antibiotics) Prague, 15-19 jun 64. A.P YO.v. Jjy, I "'O'DOLM"C", i .11. A',, iljv, I .1i. 0. G KVITX0 K.V.; K~JVISSKIY , A.L. ; Kkl.A:XVJCII, Yu.!'!.; V.A., i0laidulk, glav. red.; prof., red.; IMINA, T.S., red. I.Genctics and variation of micro-ni-ganivus] Genetika i ~-e- mikri-Orgarialov. Vo~kva, I~auka, 196-!,. 301, P. OXL~l 17:9) .1. In-;titiit atu.,uroy ,nergii imerli I.V.Kiii,cliatova (for illim, Fameneva, Kryiov, Lamov.-kaya, Yizidlm, 1~ikiforov, Lolcolova, Luklloulolcts). 2. Kafe6i-a geneti-ki Le- ningradskogo gosudui-.Mvenno,go unive.-.1-4teta (for Zakharov, -n-c-l.'eclitomov, KvItko). 3. liu,;t-itiat nucl],it~~Iolmuy 1 fi.,L~~I:o- Lhimiclic-ol:oy bic-logii (for E.rivi:~shi: ). 4. InAitut udkro- biologii Ali SSS,i 'kf'cr Kartis:.-vich). ACCESSION Nq.: AP4027986 S/0205/64/004/002/0313/03,21 AUTHOR: ZhdbLnov, V. G.; Alildianyan, S. I. MILE: Use of fast neutrons in selecting an Actinomycos orythrous erythromycin producer ,,.SOMICE: Radiobiologiyal v. 4, no, 21 19641 313-321 TOPIC TAGS: Act. erythrouss erythromycin producert fast noutron selection., induced Act. erythrous variant# fast neutron dow) (10 to 0 Icr), ultraviolot irradiation, diothylaulfato troatmont, variant antiblotie activityp fast neutron dose 11BE ABSTRAGT: The present study was conducted to test the effectiveness of using fast.neutrons to induce Act. erythreus variants with high antibiotic activity and to compare tho.9o variants with thoso induced. by ultraviolet irradiationy diothylsulfato (DES) treatmont, and DES treat.mont combined with ultraviolot~irradiation. Susporsions of Act. erythrous spores in plexiglass tumblers wore placod into spocial load ,containers and irradiated with fast neutron dosos (10 to 60 Icr) for a maximum of 6 min at 33 to 340C, After irradiation the susIxinsions wera sown on,an agar.oorn medium and antibiotio activity of oolonioa Corc, -1/2 'ACCESSION IM: AP4027986 was determined 10 days later. On the basis of fast noutron~dose RBE-,, .~the effects of various fast noutron dosos (10 Icrad and ItO Rrad) were 'compared with those of corroaRonAing ultraviolot radiation dosos (1000,ordmm2 and ItOOO ergbrme-) , Other exporiments invostigated the .OffOCtS of diethylsulfate treatment (1:100 solution) of Act. orythrous ;spores for 30 min and 60 min periods and also the effects of this trantment In combination with ultraviolet radiation (1500 t3r,E,,/vjm2 dosa) .and fast neutron doses (10p 20, and 30 krad doses). Exporimi,,ntal data .show that the largost niunber of variants with high antibiotic, activity .was induced by fast neutrons. An Act. orythrous strain (I]X.-lefu) with 60 to 70% higher antibiotic activity than in initial strain LS.-E2577 was produced by use of fast neutron selection. Orig. art. has: 6 figures and 5 tablen. IASSOCIATION: Institut atomnoy energii im. Is V. Kurchatovap Moscow (Atomic Energy Institute) :SUBMITTED: l6ju163 ENCL: 00 SUB CODE: NR 1W SOV: 003 OTHER,. 004 Card OGANNSYAN, M.G.; ALI191AAYAN, S.I. Variability in vitamin production by Attinomyces ollvacEus induced by new mutagens of the 2-chloralkyl suries. Antibiotiki 9 no.1:22- 24 Ja 164. (MIRA 18:11) 1. Vsesoyuznyy nau o-issledoiutellskiy institat antibiotikov, Moskva. 'UJFHANYAN, S.I.; OGAN~SYAN, M.G. R,alation of the mtugenic effect of 2-chloroalkylaminea to the st,ructuro of their functional groups and radicals. Vest. ANI SSSR 20 no.1:72-84 164. (MIRA 170) 1. Vsesoyuznyy Nauebno-issledovateltskly institut antibiotillov Ministerstva zdravookhrananiya SS,"R. ACCESSION NRO AP4022477. S/0220/64/033/00VO07tl/0078 jAUTHOR: MkrtumybLn, ~T. X.; Alilchanyan, So -I. ;TITLE: Biological effect of ultraviolet radiation.on aetinoiZagen I ;SOURCE: Mikrobiologi7a.. V. 33,'no.'l, 1964# 73-78 let-radiation, ultraviolet radiation biological !TOPIC TAGS: ultravi6 ,;effects actinophago# acti;nophage mutagenesisp Act. Streptomycini Bras,, ;:B"6 cultureg aetinophage n6gdtiv0'oolonyj, aotinophage radiosensitivi- i Jty, irradiated host cell ~IABSTRACT: Lack of literature data on induced mutagenesis in. :qctinophages prompted the present study of actinophage type 1-which is'. I j4ctive against Act. Stroptomycini Kras. B-6.oultures. The e:rfects of iultraviolet radiation on aetinophages were studied after two 1!experiments were staged. to determine: 1) actinophage type X growth,,..,,.- -land 2) morphology of negative colonies f9rmed by extraoollular actinophaaes and infected sprputs in B-6 cultures, A:otinophage.,typo I 1was fouAd to sprout in,Aot. Streptomyoini B-6 population approximately -75 viin after infootion'and to' continue growing for 45 min. ..,When .-actinophagos and 12 hr,sprouts of aotinomyeeto treated with eiibiohin6l Car~ 1/3 :.ACCESSION NR: AP4022477 It ,,,were-sown, large homopneous negative colonies formed in-all, the B-6 f I i-cultures, but such colgiiies-were found in only 44% 6f the eo~ntrol .group cultures. In.a Series of expeftments with ultraviolet :radiation the following were determined:,, sensitiviiy of.frbe and inhi intracellular aetinoph4ges to ultraviolet radiation., biting i:effect-on reproduction,,.and ~ffoct of irradiated hose cells on 11actinophage sensitivity to ultraviolet radiation. T4e intracellular !:actinophage was found to be 40 times mor;~ resistantito ultraviolet 11radiation than the free actinophage:andj~0 times morie resistant than ;',the noninfected sprout, An ultraviolet irradiated actinophage starts i1to sprout 30 min later tha .n in the control group. Survivability of i~nonirradiated actinophages does not change when sown on irradiated !host cells. However, irradiated actinophage's sown on ~~rradiated host] !'cells produce 4.7 times fewer negative colonies than when sown on -i nonirradiated host cells' Consequently' irradiated 0 2 aotinophages ;should be sown on nonirradiated,'host cells to increase their surv;Lva- ibility. The authors hypothesize that the genetic material o:V*the' actinophage and the host cell are homologous and that damaged ~,aetinophage genetic, material is.possibly replaced bT the host.ce iOrig.. art. has: 6 tables and 3 figures*' Car~ fit MhRTUMYAII, N.M.; ALIEHANYAN, S.I. Biological effect of ultraviolet rays on actinophage. Mikrobiologila 33 no.1:73-78 Ja-F 164. (MIRA 117:9) 1. Institut atomnoy energii imeni Kurchatova. . . . . .... ~4 A L I' .-nd lrorr~,3c',.3 in tho gencLicl of mi-croorwanisms. Gene',Ika I u 7 165* (~Uu 18:10) I* hintitut atomrio.), energiJ in. TeV.Kiii-chatova P-N SS,9Rq Moskva. SUKI:t-l . V.Va; IL1111h, T.S.; . lwl'," ". 1. ~ 0 Ali-Y-JU~IIN Gi.lne'l It-I ~- mapping of thyrminf-dep4--nident riiitLnts of Enchericl-lia rcli K-12. Genetik,.t no.l:W~-88 165. (MIRA 18:10) I.. Triotitut atormay energi-i iz,. I.V.Kurchatova AN S M-R, bloskva. &OMnVA, S.V.; KALYAYEVA, E.S.1 ALIKHANYAN, S.I._. ;Study of the genetic basic of different quantitative tlymine requirement by Eacherichia coli K-12 tWne mutants. Genetika no.1:100-105 165. (MIRA l8slO) 1, Inatitut atomnoy energii i~o 1,.V,Kurallatova AN S&SH, Moskva. ALIKHANY'All, S.T~; IfMlIJMYAN, N*M. Production of spectrum induced mutations in actinonhages without preliminary intracellular replication in t6 pha*ge ,resistant strain. Mikrobiologlia 34 no.1;101-109 Ja-F 165. (MIRA J8:7) 1. Institut atomnoy energii imeni I.V. Kurchatova. ".. , 1, 1, " J:! !,-Ji - - -V jr li 'o-; ". "'.j *-1- , recor,lilnitiont- In bac"I.-Iria. Unp. rrik-roldol. I&', . (,,ITI'A 18:9) mmoog S VAE*R& Mm I F mugg-nuagra Eil zm. PI hubmraErawrAmIZ4 "M LI D"- ------ ------ -2~ --7~7-7- _7 -T 1 46 6 VIT I 3,97. JVZWA b) 2 RO J!R%,= bM: AM 699 138/03-41 P 003 /0216/65/000/00.V it! THOR I Zbdwqova~ N. I.; AlDhuh7anp S, is "I TLE, Effecl~, of strfbilIZ7'ng selection In breeding &n o-Leandomycin pi odu-^ E r 15 C - 17R C E :AN S.SSR. Izvestiyjt. Seriya bloloRlcheskaya, no. 1, 1965, TOPIC IAGS: Act. antIbioti.aug. ole-andomycin producer. wijtation, --,t 71 I-7=1 1p:- Ma Ej E2 Cord 1/2 a WAAA&D . PUYWOU VILI -V-APUBA-Ut~r and the selection of armll quantitative doviitions (jaLnute mutatlLons) leads to stabilization of the characteristic in the Population at a certain threshold, With a'high degree of himiogentkity in apopulation, a now variability shift can be produced mider the action of mutagaitic factom, Orig. art. has: 2 tables and -L-" ASSOCIATIOR. -V4je3o Uchn"ts sled6vat6l# skLy - Inst YUS _nOtit"te, of _4htjbj__ I-Al-I Unto: nt i-f lom-B e-s a-arch 0 SIMMrMfl): 02Apr64 IMCL.. 00 SUB 'COIDE: LS MaMww. Mia" Ira WK12 LEY MMUMM~ I 56&_5_65 tmvw: AP50103591 UIV0205/0/00/002/0WO308 AC 5 AliklkapM gs~ 10' -AV1HDR:_:L2hdwovi6 -N.- I.;-Zk WIT' 7:- - -A -comparison-of-ft6t-neuirowilf -X-rapi- and -ultraviolet rayo w1th chemical mrtagens in antibiqtirAwl selection SOUPCH: Radidbiologiyap vo- 51, IW4 2, a965P 304-30B 32,--antiblotle--producer selectionx mutagenp-fast 8~*--ant to netutron dose ~V~on). ultraviolet ray Irradiation) ethylenlrump diethyistCffate. radiation induced mutation AN p AA "0 roe- ite, - biold- __:01~ penaedia.vater vit a t r of 1.10,10 Spore AeAUR-i Olloving 5 Mitapas to evaluate their relative --i-effi.-ctivei3~-es---Iw-eelectil6n -of -v~~iblotlc -producers: --ethylenimine - (0.1$), diethylstiLfate (0.2%)., fast neulMs. X-rayst and UV rays, Chemical intagen at '28U Two ~ BW,15 bactericidal lemps (104 er e/sec) treatment vas conducted- .9 Vetze-used as -a- UV source)- a-clone.f0f.,using -tube- of a TOM-7 unit ~ -(60 )or, - 20- maj7 5.17, r1rdn) vao used as an X-rW source,, wA a IOD kv re-setor (16 rade/sec, gw1ha-background. 2-3 rade/see) Ws used for. fast neutrm irradistione The -effect 7-1 of each inata*n on spore survival'sal antibiotic prodaction variabilfty was 1/2- ASR)CIATION: Vaero-yuzwjy nsucbma-issledovatellskiy institut antibiotlJwvp VDskva (~..l Uaion Scientific-Rese.-Amb Ittati4,-ute of Antibiotics, MDscov) stumTED: o6Apr64 ENCL: 00 SUB ODDE: LS M Eff STV 007 OTEM: 002 2/2 L 1619-a .ACCESsION NR.:, AP5017164 Un/o~16/65/oo*OV0542/049 .575.24 :AUTHOR: A?~:k anyon 1,; Grinbergo K, No; Krylovp Ve N#11; Maysuryan# -'A* No; Ogaiiii p He G* C~o .6 !,TITLE: Temperature-eansitive (ts) mtants of baoteriophago T4B ZOURGE, AN SSSR, Izvostlya, Seriya biologicheskayap no, 4,p 1965# ~TCIPIG TAGSt bacterial genetics,, biochomistryp temperature :characteristic 110TRACT: A new method of inducing temperature-sensitive lbaoteriophage T4B matants with disturbed synthesis of various ienz7riesp particularly those required for DNA synthesis., is described* qali k strains were infected with baeteriophage, TO and cultivated 11 VuroTh using 2*6-diamihopurine, hydroxylaminep ultravi,Dlet lightp band 5-bromouraoil as mutagenic agents* Mutants were selected from i :a total of 298 colonies by methods of absolute selection, I Mlnute-phen6typey and antiphage serum. In contrast to phage T4B# the nitanto behave differently at 27 and 42 G& Hydroxylaminewith Card 1/2 t, 1619-M 1ACCESSION.M. AP5017764 .mitirhage serum yielded a high percentage (15-20%) of ts-natants. iPvellminary classification 'of the ts-mutants by a oomplementation !tost divided them Into 50 sPoupso Some groups had 4-7 mutantsp others 1,2p and the majority one. A; physiological study of the ts-mutants ,Isl.-iowed that their thermal sensitivity is related to the tbermolability lo.r the intracellular developmental stages. Differences were found ini ,matant inactivation kineticis when applying the one stop growth cycle ; laocording to Adams at 42 C.j On the basis of these differences the I Matants may be divided intc',4 phenotypes. The fact that these mutant4 wDre preliminarily distribuited over 50 groups indicates that many iganes are affected bry mutations, The tests confirmed the assumption, ithat conditionally lethal rutations may be induced from the bacteriophage T4B# Orig*.arte has: -6 tables and 2 figures, 1ASSOCIATION: Institut atortno-y energii imi, 1. V. Kurehatova !(Institute of Atomic Rnergi,~) suBmiTTED: o8ax=64 1RiCL s 00 SUB CODE: LB NR MW BOV 1 002 OTM: 006 ~R~O - 2/2~-- I D FEDOROVAt I.V.; ALIKHANYA.I.L-S.1- Charaoteristios of the variability of ActinotWoes aursoficiand strains in rempeot to the produation of antibioties under the effoot of mutant aotinophages, Antibiotiki 10 no&7t579-585 Jl 165, (KIRA 180) 1, Vsssoyutnyy nauchno-issledovatel'skiy institut antibiotikov i Institut atomnoy imergii imeni I&Ir. Kurohatova, Moskva. i hl, I A NYN Ntitur -.A L iind inducel vari bb~ I i ~ v to pr(vdurtion of' anLibi,-)ticSon vari.,)u.3 virid~a. Ar. 11) no.~,-'U,0-713 Ag 16,5. 1. Vsvsoyuzrivv institut. LCMOVSKAYA, N.D.; ALIKIIANYAL.L.J. ------ ~w - Characteri sties of the effect of 2 ac'U'nophages cn, of Actinomyces Epherobles. Ant-lbictAM- 10 no.9:793-SCKC) S t65 110 (, wi 18:9) T.V.Kurchatom, tPosilmi. 1. In-stitut atomnoy energil-I JMp ' ~11FHANVN.. r.-j, jc,*t;ipn (Y-ager 14endql, 1822-1884. Mikribiolog-lia 34 no.40)31-739 J'i---,g 165. (mrfu -.18.n0) A7.IKIIANYAN, S.I.; ILUNA~ T.!~.s KALYAYEV-4, E.S.; KAMENEVA- S.V'.~, s[I.F.HMOUTS, V.V. CharacterJqtics of Racharichia. cali K 32 mutants with Imoui,red tymid,vlic acid syntheadzIng system, Mjkroblolcglia 34 nc.4*.'Su-- 675 Jl-tw 16154 (MIRA 18:10) 1. Institut at-omncy energ-li. imrzni I.V,Yurrhatova. ALIKHANYAN, S I.; FEDORCYVA, I'VI - - W- Sarcolpine induced mutations in actinophagee lysing thei ittrains of ActinoWces aur-sofaciens. Mikrobiologlia 34 no-3v450-455 W-.Te 165. (MIRA 18il.1) 1. Institut atomnay energii imeni I.V.Kureh&tova i Vsea& iznyy Yl nauohno.-iseledovatallakiy institut antibiotikove SUKHODOLETS, T.V.; ALIKHANYAN., S.I. Thymidine-sennitive gene in Escheriabla coli K-12; phenotypical expression and chromosmal localization, Genetika no,Z;47-53 Ag 165. (NIRA 18:10) 1. IS. Kurclmtov'B Institute of Atomic Energy, Moscow. RUBIKAS, I.; ALIMMAN, S..I. N Crosa-transformatian of mutant T-4 phiagem. Dokl. All SSSR 153 no.6tl487-1490 Ag 165- (Yll-RA 180) I.. Submit-ted Novembar 3, 1964. ALIKHANYAN, S.I. Some problems ol' the mechanism of =tagenesis. Izv. LN ISSSR. Ser. biol. no.6:825435 N-D 163. (MIRA 7LS: 1.1) 1. Instiut atowioy energii im. I.V. Kurchatova. ILOINA, T.S.; ALIKHAITIA1, S.I. Burst of phage of PI kc from &cherichia coli K-12 mutEnts with disturbed system of thymidylic acid synthesis. Genetiks. no.3:105-110 S 165* (MlRL JE;:12) 1. Institut atomnoy energii imen! I.V.Kurchatova, Moskvij. Submitted May 6p 3965. RIJBIKAS, I.; ALIKHANYAN, S.I. Transformation of phage T4rII br using uninjured phage. Genetika no.5:11-13 N 165. (MIRA 19:1) 1. Institut ELtomnoy energii imeni I.V. Kurchatova, Moskva, i Institut botaniki AN Litovskoy SSR, Vlllnyus. Submitted August 23, 1965. -7:v ~i RUBIKAS, l.; KRYLOV, V.P.; ALIKIIANYAN, S.1. Transformation of phage T4rIl 250. Genetika no-5:14-18 R 165. (MIRA 19:1) 1. Institut ato=o), energii Imeni I.V. Kurchatova, Moskva i Institut botaniki AN Litovskoy SSR, Vlllnyus. Submitted August 23, 1965. 4 ALIIDMHXIN, A.; GORCHEV, I.; MATOROVp To. I Highly efficient calculating machines in the service of economists. Fin.SSSR 37 no,208-61 F 163. (MM 16:2) (Funched card systems-Budget) I ,AL LK tLk~_Li K LE _ A.1 elks qN i~ 7EV, Ivan lvanovich; MAYO.I.GV, v -Ljjjcb; GORCh Yevgeniy Semenovich; 1-TEDVEDEVA, R., red. [Mechanization of planning and accounting work in financial organs) Mekhanizat-dia planovo-uchetrykh rabot v finanso- vykh organakh. Moskva, Izd-vo "Finansy," 1964. 92 p. =7-77-7-71-- SOV/ 124- 58-10-11321 Translation from- Referativnyy.zhurnal, Mekhanika, 1958, Nr 10, p 89 (USSR) AUTHOR: --Aji~khashkin, Ya.l. TITLE: A Method of Cornputili-g-the Y.*cld of a Pressure Inflow to a Well Which Does not. Completely Penetrate an Aquifer (Odii.,i sposob ras- cheta debita dlya napornogo pritoka k nesovershennoy skvazhine) PERIODICAL: Vychislit. matematika, Nr 1, 1957, pp 131-135 ABSTRACT: The Abel-Euler method is employed to improve the convergence of series encountered in the expressions for the constants of seepage resistance and mean potential values along a section of the xell within an aquifer. Tables and graphs are given which pern-iit calculation of the yield of a well (which does not completely penetrate the aquifer) with an accuracy sufficient for all practical purposes. Bibliography. 5 references. V.A. Karpychev Card 1/1 Elm ffj~ EMLQNK~ lots;P Mau 11 2ffl a naur A.LIKHASHM10 Ta. I. Sol:,ring the problem of an imperfect well by the method of straight lines. Vych. mt. no.1:136-152 157. QR&104.11) (Fluid mechanics) (Differential equations) (Determinazte), ALTIMA HKIII., Ya.b, YUSHICINI, A.L Using electronic calculating machines for hydraulic calculations of water-supply systemos Gor. khoz. Moske 34 no-11117-18 N 160. (MIRA 13:11) 1. Ucheny7 sekratarl Vychislitellnogo teentra Akademii nauk SSSR (for Alikhashkin)o 2. Glavnyy inzhener proyekta Instituta-Imosinih- proy-ekt* (for YushkJA). (Xlect,ponic calcu.1-ating machines) .t-(Watez~-suppl,v engineering) CHISTOVAp B.A.;ALIKHASHKIN, Yaj *I- kand. viz.-mat.naukp otv. red.; ORIDVA~ KORKINA) Mey tekhns red, I [Standard programs for the "StrelL--3" compaterl Standartnyv progranmrq dlia masbiny "Strela,-3." Moskwa. No.3. [Calculation of Bessel's functionsj Vychislanie funktsii Besselia. 1961. 39 p. (KMA 1!i: 1) 1. Akademiya nauk SSSA. Vychisliteltryy tsentr. (Besselle functions) SRAGOVICH, A.I.; CHAYKOVSKAYA, E.V.441;14~IN, Ya.l., kand. fiz.-mat. - - - - -t-e'k nauk; ORLOVA, I.A., red.; KORKlNA, A.I.y , hh. red. [Standard prograw for the "Strela-3" computer) StandartM-e programag, dlia mashiny "Strela-311. Moskva. No.l. 1961. 47 p. No 2, 19619 36 p. 6MU 14:10) 1. Akademi-ya nauk SSSR. Vychislitellnyy tsentr. (Progr4u=ing (El6ctronic. computers)) ALIKIIASIIK.-N, Ya.I. (Moskva) Numerical integration of the equati,)n of an automatically simulated movement of the boundary surface of two liquids in a poroijs medium. Izv.AN SSSR.Otd.tekb.nauk.MekhA mashinostr. no.5:159-16:a S-0 161. OGRA 14:9) (Hydrodynamics) ALIKUSWIN, Ya9I* (Hoskva); FAVORSKIY, A.P. (Moskva); GRUSHKIN, P.I. (Moskva) Calculation d"W "In, a.---f2at Lav4 nozzle* Zhur. vych.-Mat i rat A fiz. 3 no.6:1130-11jim".141, 63- (MIRA 17tl) TATAROV, Z.1,; ALIKHASHKIN, Ya.I., kand. fiz.-matem. nRuk) otv. red.; (Standard programs for the "Strela-3" computer.] Standartnye programmy dlia mashiny "Strela-3." Mosk-m, VTs, AN SSSR, 1962. 8 p. (Akademiia nauk SSSR. Vychislitellnyi tsentr. Standartrye i tipovye programmy dlia mashiny "Strela-3,11 no-4) (MIRA 18:1) ALIKHASHKIN, Ya.I., kand.fiz.-matem.nauk; KANTOR, B.Ya.; MARCHENKO, G.A.; ORLOVAY I.A., red.; KORKINA, A.I., tekhn.red. (Standard programs for the "Strela-3" computer] Standartnye programmy d1la masW.ny "Strala-3." Moskva, 1963. 15 P. (Akademila nauk SSSR. VyclLislitellnyi toentr. StAndartnyo i tipovye progr4my dlia mashiny "Stralit-3,n no.5). (14IRA 16:10) ALIKHASHKIN, Ya.l., kand. fiz.-matem. nauk; KHOMENKO, Yu-V., inzh. Dater-mining the form of the knife of the picker cylinder of a silage harvesting combine. Trakt. i sellkhozmash. no.5: 23-26 My 165. (MT-RA 18~,.6) 1. Vyohislitellnyy tsentr AN SSSR i Vsesoyuznyy nauchno- iseledovatellskly institut sellskokhozyaystvannogo mashinostroyeniya. 4`-~ N AUTYE"YAWC, ~: A .USSR/Cheriistry Specific Heat Card 1/1 Authors Kostryukov, V. N., Alikhanyants, R. A., Samoylov, B.. N." and Strelkov, F. G. Title Termodynamic Stidles at Low Temperatures. IV. Methods Por Measuring the -Specific Heat,of Condensed Gases. Periodical I -Zhur. Fiz.,Khim., Vol. 280 Ed. 4v 650-655, Apr 1954 Abstract A general description is given of a calorimetric apjari~tus, used for measuring the specific heat of condensed gases at low temperatures, and the determiriation of thevolume of gas by means of weighing it under condensed~,[condition. Four references; tables; griaphs, drawings. Institution S. I. Vaviloy'sjnstitute of Physical Problems of the AS of the USSR Submitted, June 8. 1953 fj-1 /V- 1P. 2- 21150) PHASE I BOOK EXPLOITATION USSR. Upravleniye po organizatsii i mekhanizatall ucheta SOV/1672 Mekhanizatsiya ucheta i vychislitellnykh rabot na promyshlennom pred- priyatii; obornik statey (Mechanization of Accounting andi Comput-' ing Operations in an Industrial Establishment; Collection of Arti- cles) Moscow, Goastatizdat, 1957. 125 P. 5,100 copies printed. Additional Sponsoring Ager~cy: USSR. TSentrallnoye statisticheskoye upravleniye. Ed.: V.A. Ustiyants; Tech. Ed.; A.A. Kapralova. PURPOSEt This book is intended for technical personnel servicing computers, tabulators, punch card machines, etc., and.for those using this equipment. COVERAGE: This collection of articles reviews various aspects of mechanical invoicing, use of key-operated calculators in account- Card 1A Mechanization of Accounting (Cont.) SOV/1672 ing, functions of inter-plant clearing houses, accouhting of state taxes using business machines and computers, and operation of punch card machines. Technical features of computing and calcu- lating are discussed and some measures to Improve reliabflity are outlined. No personalities art mentioned. There are 8 Ir"oviet references. TABLE OF CONTENTS: Galiyev, A. Ume of the FM11--III Invoicing Machine for Simultaneous Printing of Three Billing L\acuments 3 Gavrilov, G. Mechanization of Finished Product Accounting U;31ng Key-operated Calculators (Based on the Experience of the Shadrinskiy Avtoagregatnyy Zavod-Shadrinsk Automatic Calculator Plant) 13 Veprinskiy S Mechanizating Operations of an Accounts. Clearing House (BVRj oi a Construction Trust 20 Berezin, M., and A.Alil~hAshlK"n Methods of Getting the Accounting Leaf and Insert I-nV6-_ff6 Face Account. Accounting of State Taxes Card 2/4 I Mechanization of Accounting (Cont.) SOV/1672 (Experience of th'e Computing and Business Machine Service Center of the "Yuzhuralnikell" Combine) 27 Lazarev, V... and A. Safonov. For Further Improvement of the Mechani- zation of State Tax Accounting 32 Potekhin, S. Methods of Perforation Control 40 Isakov, V. On Perforation Control Methods 53 Rapoport, Le. Effectiveness of Mechanized Engineering and Toch- nical Calculations 56 Rappoport, M. Technique of Calculating Finite Differences on Computing Machines 80 Khusainov B. Compilation of Calibrating Tables on Tabulating Machines tExperience of the Computing and Business Machine Service Card 3/4 Mechanization of Accounting (Cont.) SOV/1672 Center of the Novo-Ufimakiy neftepererobatyvayushchiy zavod.- New Petroleum Riefinery at Ufa) log Tikhomirov, Yu., and N. Kotov. Automatic Etopping of the Tabu- lator and Switching on of a Light Signal With the Appearance of a ".Short" in the Tabulator and the Totaling Perforator 120 Fokin, N. Modernization of the Totaling Perforator for the T- 4XI Tabulator 123 AVAILABLE: Library of Congress (HF5679.R8) JQAg Card 4/4 8-5-59 GUSENKOVt V.; -~AIJAW jAjjNp. A. Practice of me--hal%izing the processing of reports on earring out the state budget. Fin. SSSR. 22 no. 2:83-85 F 161. ~ (MIRA 14 z2) 1. Glavnyy bukhgalter Moskovskoy pechatnoy fabriki Gosznika (for Gusenkov). A".. Nachallnik tsekha mekhanizirovannogci ucheta Moskovskoy pechatnoy fabriki Gosznaka (for Alikhashkin), (Moscow-Printlng industry-Accounting) (MachJ49 accounting) -E-I-MASEB, YA. I. ALIKIIASWIN, YA. 14. "Methods of Approxinkite Solution of One Spatial Problam in the Theory of Filtration (Pro"t-len, of Impi!irfect Well). "Acad Sci USSR, Inst of Procision Mechanics and Computation Enrineering., Moscow, 1955 (Dissertations for the Degree of Candidate of Pkysicomathematical Sciences SO: Knizhnaya Letopial No. 26 Juno 1.955, Moscow ALIKHAYAN, S.I.; LOMOVSKAYA, N.D. Genetic recombination in actinophagen. lzv. AN SSSR. Ser. biol. no.5s721-726 S-0 t64. (K*RA 17:9) 1. Institut atomnoy energii Jm. 1.V. Kurchatova AN S'SORP Moskva. SXNIKO, M.1r.; SIAVIKOvSKIY, N.A.; ALIKHODZHAN. B.A.: gILIN. L-G.. inzh Lengthening the lift) of rails- ]F'at' i Put-khos' no.12:21~ D '59- (NIRk 13:4) 1. Gla*,W inzhener eluzhbY Puti Moskovskoy dorogi (for Se,nll*. 2. Zamestitell nachtl'rAkp distantaii puti Moskovskoy doragi (for Slavikoveldr). .3. Starshiy inzhener aluzhby puti Mookovskor dorogi (for Alikhodza:a)* (Railroads-Ra-11s) ALIKHODUATEVA, M.A.; GUDKC7, L.V.; SHEKLEINP A.V. Selective coating of receivers of radiant solar energy, Gallo- tekhnika no.6:19-24 165. (MIRA 19: 1) 1. Gosudarstvannyy -tauchno-looledovatellakly energeticheekly institut imeni Krzh:l.zhanovskogo. L 349-66-- MW/Ap(A)./T lip(c) - uaf ACC NRt AP6017561 (14.) SOURCE CODE: up/6377/6~1-C-op-) AUTHOR: Alilkhodzhayeva, M. A. Gudk L. V.; Sheklein, A. V. 17 Institute im. G. M. Xr--hishn'10"'Shly ORG: (GosudarstvenrWy n.-i. energeticheskly institut) TITLE: Concerning selective contiogof receivers for radiant energy from the sun SOURCE: Gelioteymika,. p0. YP 1910p 19-24 V - e C -A!---~0- I TOPIC TAGS.- zolaylfurnace,, solAr j1dwer plant, paint, solar radiation absorption/ KhS 77 enamelp DM nitro dye a4v,, e-, - ;,-C - ABSTRACT: The purpose of the investigation was to find a more universal paint for solar xadiation receivers, such as would absorb the incident radiation in -the spectrali rarW,e which produces low effective beating and would have a minimum emission in the region of the intrinsic thermal radiation of the receiver. Tests made on various Soviet enamelsfound chat the most natisfactory results were obtained with the natural- drying cnamc]AW-77) which is a solution of the copolymeryof_vinyl chlortil-4and vinyl. diene chloride mixed with volatile i)rganic solveriE ~,p g~ment'- and filler. e coef- ficient of/ absorption and the degree of blackness of this enamel are compared with the nitro d yt'tm and the advantages of the former are demonstrated. A procedure for coating the solar radiation receiver with this enamel and calculating the heat loss in * vater boiler treated with this entunel are presented. Plats of the beat loss of such * uoler with variation of temperature are presented. Orig. art. has: 3 filpires, 3 ~forTiulaa, and 2 tables. SUB CODE: 64~,3/ Sum DATE: L>7sep65/ om REF: oo4 DOBRICH, Adallbert [Dobri6, Adalbert]: ALMODZHICH, Asim (tvanalatorl; PISARRY, I.Yu., prof., red.; red.-; LATYSIff, A.I., red.; YINOGRADOTA. Y.A., tekhn.red. [industrial statistics]. Promyehlennsia statistika. Pod red. I.M.Pisareva. Nomkva, Gos.stat.izd-vo, 1959. 291 P. (MIEUI 13:3) (Industrial utRtistics) O1MNIKj LP~j kand. okon. naukt nauchn. sotr.; VOINOV, A.M., nauchn. sotr.; SEIMOV, I.I., naucbn. sotr.; PIAKS11i, S.V.., nauchn, sccr.; KACHALDV, LP.p nauchn. aotr.; SEPMOVA, L.S., nauchn. sotr.; STOR07JXV, I.V.1, nauchn. sotr.; CMSOVICHO G.B.., nauelm. sotr.; SERGEYEV, V.P., nauchn. sotr.;.AL1K1jQDZH=H'-A.-j nauclui. sotr.; LISGV, V.7e., rod.; NIKOLAM, red.; PONOMAREVA,A.A., tekhn. red. (International socia3ist division of labor] Sotsialisticbeskoo mezhdunarodnoo razd~lenie truda. Pod red. I.P.Oleinika. Mo.. skva, Izd-vo ekon. lit-ry, 1961. 350 P. (MIRA 14::1.1) 1. Akademiya nauk SSSR. Institut ekonomiki mirovoy sotsial-isti.- cheskoy sistemy. 2. Institut ekonomiki mirovoy sotsia-listichelikoy sisteny AN SSSR (for a-11 except Lisov,, Nikolayev, Ponomareva),, (Conmunist countries-Division of labor) -. ALIXHODZMII, B.A. Rail tooter with a spotter operating under the rail head. Put'i put.khos. 4 no-7:22 Jl 1600' (NIRA 13:7) 1. Ittmehly inshener slushby puti, Moskva. (Railroals-Raile-Testing) ;I pglgaNCWN'tej*,~~o~,, KOCHEAREV, F.Ya.j ALIKHODZHIII, B,A. We don't miss a singXe defect,, Putt i put.khoz. 6 uo.12z;!5-:)8 162, . (muuL x6:itl) 1. Nachallnik vagona.-defektoskopa Moskovskoy dorogi~(for Kochkarev). (Railroads-Rails-Defects) AIJKROV, X.N., inzh. Standardixation of pipeline fittings. Sudostroenie 27 no.603-54 Je 161, (MIRA 14:6) (Marine pipe fttting) ALIKHOVA, T.N. I--- ..- -7;;-r= History of the development of the Russian Platform in tbe Ordovician parlod. Trudy Geol. muz. AN SSSR no.14*27-28 163. (Iqm 17; 11) [Brachiopoda of the middle and upper portion of the Lower Silurian in Leningrad Province and their stratigraphio significance) Brakhiopody arednei i varkhnei chanti, nishnego silura Leningradskoi oblasti i ikh stratigrafichookoe snachanie. MoBkva, Goo.izd-vo gool.lit-ry, 1951. 80 p. (MMA 12:12) (Ioningrad Province-Brachiopoda. Fossil) ALIKHOTA, T.N.; NIKIFC-ROYAO 0.1., redaktorl TOLKOVA, A.S., redaktor; tekhnicheekly rodaktor (Leading brophlopod fauna of Ordovician deposits In the northwestern part of the Russian Platform] Rukovodiashchaia fauna brakbiopi)d ordavikskikh otloshenti severo-sap"not, chasti Rueskol platfwmy. Moskva, Goo. izd-vo geol. lit-ry, 1953. 160 [31 p. (=A 7-9) (Brachlopada, Possil)