SCIENTIFIC ABSTRACT KONSTANTINOVA, L.F. - KONSTANTINOVA, N.A.

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SCIENTIFIC ABSTRACT
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AVERSHIM, S.G.,prof.,doktor tekhn. nmult,rad., BWXHA.Ye.Te.,gornVy inzh.,red.; BUSEVICH. T.7.. gornyy inzh..red.; UUMOV. L.A..gornyy inzh.,red.; LISHUTIN. B.G., goraVy inzh.,red.-, OGLOBLIM. D.N.. prof.. doktor tekhn. nauk,, refd.; ONMICHMO, A.K.,kand. takhn. nmuk, red.; RYZHOV. P.A.. pref..doktor takhn. nauk,: GLAZEMAP, K.K., insh.,red.; red.; HIKITIITA. H.H.,inth.,red.; MOVOSILOVA, Yu. A.,insh.,red.;S=100, Ye. I.,inzh..red.; TAKOVL1V* X.G.,inih..red.; RASHKOVSKIY. Ta.Z.jnzh..red.; STELIMAKH. A.M.. red. izd-va,; BEHLOV, A.P.,tekhn. red.; NADEINSEATA, A.A.,tekhn. red. (Transactions of the All-Union Scientific and Technical Conference on Mine Surveying July 17-23. 1956J Trudy V6*8OiU2nogo nauchno- takchnicheskago soveshchanis po markshaiderskomu delu 1'1-23 Lulis 1956 g. Moskva. Ugletakhisdat. 1958. 743 p. (MIRA 11:12) 1. Vaosoyasnoye nauchno-tekhnicheakoye soveshchuniye po morkaboyderskona delu. 1956. - (Kine surveying) MILOGRADOVA, Ye.l.; MALAKHOVA~ P.T.; ~R~~TANTINOVA~ L.G. Bacteria accompanying the mass Chlorells. culture and their role in the biosynthesis of vitamin B124 Uzb, biol. zhur. 9 no.51 18-20 t65, (MIRA 18:10) 1. Inatitut botaniki AN UzSSR. MALAKITOVA, P.T.; KONSTANTINOVA, L.G. - Microflora of the mass culture of Chlorella. Uzb. biol. z1hur. 9 no.2:24-28 165. (MULk 18:5) 1. Institut botaniki AN UzSSR. 133-8-13/28 AUTHORS: Ko nst ant inova j Io`0I.j Lemlekh, Ya.M.j and Frenkel't L.A. TITLE: Gaseous preheating of rolls for rolling thin sheets. (Gazo7yy podogrev tonkolistovykh valkov pered ustanovkoy). PERIODICAL: "Stallif (Steel )",,,No-a, 19579 Pp.724-727 (USSR)'. ABSTRACT: Preheating of rolls for rolling thin sheets before assembling in a rolling stand using a gas fired heating installation and.the influence of such preheati3~g on the durability of rolls and the output were investigated. The installation for.preheating was described earlier (Ya. M. Lemlekh~ "Sbornik Ratsionalizatorskikh Predlozheniyy Vnedrennykh v Proizvodstvo,"Ts.IIN MChM, vyp.54,1955). The distribution of thermocouples used for measuring roll tem- peratures is given in Fig.l. Heating of rotating (1 rpm) and stationary rolls was tested. Temperatures of experimen- tal stationary and rotating rolls and the waste gas in various points of the heating chambers (A), pressure in the chamber and suction in flues (B), pressure of producer gas before the burner (V) are given in Figs.2 and 3 respective- ly. Changes in the distribution of temperatures across the roll from surface to centre at given time intervals are Card 1/2 given in Fig.4. It was found that withpreheatimg of rolls the output increases by 8-10% with simultaneous improvement - - - -------------------------------------- ACCESSION MR: AP4019809~ S/0279/64/000/001/0078/0064 'AUTHOR: Kasatkins, He A. (Moscow); V19dorovich, V. N. (Moscow); Nikitine. Z. he (Moscow); Uvarove, E. So (Moscow); 1. (Moscow) Behavior of Impurities during the crystallization refining of Indlum TITLE: SOURCE: AN SSSR. lav. Metallurglys I gornoye delo, no. 1, 1964, 78-84 'TOPIC TAGS: Indlum, Indlum refining, crystallization refining, Impurity ellmina- tion, solid phase soluble Impurity, solid phase Insoluble Impurity, zone refining ABSTRACT; A systematic study was made of the behavior of impurities and the con- ditions present during their elimination from Indium in the process of crystallize-:- t I on ref I n I ng f rom mo, I ten mater I a I . I nd I uffi spec Imens -wi.th - a known I mpur I ty content' bjected to zone refining In a nitrogen (Cd, Sn, Pb, H9, Fe, III, Cu. Ag) were su stream on equipment with one or two heating zones. Crystals extracted from the -3 smelt In a vacuum furnace, at a residual pressure on the 'order of 10 mm H9, were 100-115 mm long and had.a diameter of about ? 10 mm. The rate of extraction ranged .~from 0-3 to 2 mmlmln. The evaluation of the experimental results employed the author's theoretical classification of Impurities present In Indlum as either easy or difficult 'to eliminate. The former:lnc,lude most of the 'Impurities present, are ~Eha-acjpjlzed by poor,solid-solution solubility In in and have d tribution co- or 7- tarcr KISUIEVA, N,S.; SOKOVA, 0-T.- K(",N-S TANTI NOVA) L.N.; Chromoscina sets and the rat#:! cf tumor gruwthl s-C '.;~o sub.,,-,raino of the asuitic hepatorad of rats. Vupp. onk. !l 165. 1. !z laboratcri-L tsitogenetiki (zalr. - doktor bic]. nauk Ye.Ye. Pogosyants) insti-cuta eksperLmentallnoy i klinicheskoy onkologil AMN SSSR (direktor - daystvi.telInyy A.1-IN SSSR prof. N.,N. Blokhin). KONSTANTINOV, G.N.; KONSTANTINOVA,__L.S.; FILATOV, V.A. Determining the zero point of the level of magnetic anomalies. Geol.i geotiz. no,5:91-92 161. (MIU 14-.6) 1, Sibirskiy nauchno-issledovatellskiy institut geologii., geofiziki i minerallnogo syr ,ya- Novosibirsk. (Ma;n;tiC anomalies) I: A t58 Jill I M, ,b:11 mu: X(RISTANTINOV, G.R.; KONSTANTINOVA, L.S.j SERGEYET, T.O. Methods for the cop-ersion of a magnetic field in the upper disoontinuity as revealed by a study made in the western part of the Siberian r1atform.. Tftdy SNIIGGIMS no. 30&127-w1-39 1 64. (MIRA 19t1) KOUSTAIM11OV, G.H.; KOUSTANT111011A, L.S. Interpretation of magnetic anomalies by the curves of a 11orizontal gradient of Z function. 'Audy SMIGG111-0 no.27 -.138-14.4 '62. (14DU 16:9) 1. Sibirskiy nauchno-issledovatel'skiy instiLut geologii, geol'11- ziki i minerallno o syrlya. Wiagnetle prospecting) XONSTANTINOVI G.N.; KONSTANTINGVA, L.S. - Calculation of pseudogravitationul anwalies and the determination of the angle of Slope 4n magnetization voctor. Tnidy SHIGGIMS no. U 27:1.65-170 162. (MIRA 16:9) 1. Sibirskiy nauchno-issledovatell.zkiy ins-litut geologii, geofizild i mineralinogo syrlya. (Magnetic anomalies) SHAKOVO V.M.; KONSTANTINOVA, L.Ta. Significance of types of higher nervous activity for understanding some postoperative implications in the surgical clinic. 713101.2huro Wkro) 2 no*3:47-54 JW-Je 156* (NLRA 9:11) (TIKPXRAKW) -- (OURATIONS, SURGICAL) L 1. Ye. Konstantinova, L. Ye. *The effect of operation upon the prothrombin blood content,$ In the symposiums- V. N. Shamov, Kiev,, 19490 p. 179-P SO: U-4355v 14 August 53, (tatopis '2wxml Inykh Statey,, No. 15, 1949) XONSTARTINOTA. 1. To. ~'- ~,- rur oskva 70th anniversary of Vladimir Nikolaevich Shamove IhI glia K no. 10:72-74 Oct 1952o (CLKL 23:31 1. Shamov to at present Learned Secretary of ~b* vork 0"1 Novatsker - mijitabw 'r- YAlikey -0techestwennay Toy" 19U-1945. [Irperlenco of Soviet Kedicine during the Great Fatherland Wair of 1941-19451. XONSTAMINDTA, LeYe. Results of duodenojojunostooV in chronic duodenal stasis. Tests k*tr. Grokona, Lardap. 72 no. 3:59-63 Mw-June 1952. (CLHL 22:4) 1. Of the Departuent of the First Faculty Surgical Clinic (Read - Prof. V. N. Shamov). Hilitaxy-Nedical, Acade" inent S. K. Urov. SITENKOJ, V.M., prof. (Leningrads K-9, u.1. Lebedeva, d.10-b., kv.2); KONSTANTINOVA, L.Ye. Large cystic duct stump and its significance in the occurrence of the so-ca.Ued postcholecystectomy syndrunb. Vest. 10dr. 91 no.10t 12-18 0 163. ORIRA 17:7) 1. Iz fakulltetskoy khirurgicheskoy klinW imeni S.P. Fedorova (nachallnik - Prof. V.M. Sitenko) Voyenno-meditsinskoy ordena Lenina akademii imeni Kirova, Leningrad. SAGORTSCHEW, B. (Zagorchev, B.1; KONSTANTINOVA, M. The tartrate iron complexes and their use in separating Fe**,- from Fe00-ions, Doklady BAN 15 noo7:747-750 162. 1. Vorgelegt von Akademiemitglied D. Iwanoff (Ivanov, D.]. ZAGORCEZV,, B.; AgNI"Ti="Al The iron tartrate complexes and their utilization in the separation of ferriiono from ferroions. Godishnik khim tekh 8 no.2:73-79 161 [publ. f62]. - 11, SCHrJ'rANOW, Gh. (Sheltanov, Kh.);_.LON*=Zj3Q , M.; GAVDAROVA, R. [Chavdiii-ovix, 11.1 Automatic microcoulometric titration of bases. Doklady BAN 17 no. 8:721-724 t64. - 1. Vorgelegt von Akademiemitglied D.Ivanov. ALEKSEYEV, V.N., arkh.; XONSTRITINOVA, B.A., arkb.; LOPOVOK, L-I-,, kand. arkb.; M --~'Ah. - Prinimali uchastiyes BOGUSIAVSKn A.I.,. inzh.; LIVSHITS, A.M., inzh.; MASHINA, N.N.9 inzb.; ANDREYEV, V.S.p retsenzentj BOTVINKIN, O.K.p doktor khImp nauk, prof.t retsenzent; POSOKHIN, M.V., reteenzent (Catalog of finishing materials and produots) Katalog otdoloch- rykh materialov i izdelii. Moskvap Gosstroiizdat. Pt.3. 1961. 60 p. (MIRA 18:4) 1. Moscow. Vaeaoyuzvyv nauchno-issledovatellskiy institut no- ,vykh materialav. 2.. Rukovoditell Arkhitakturno-stroitel'Mm sektorom V;esoyusnogo nauchno-issledovateliskogo instituta novykh stroitellnykh materialov, Moskva (for Makotinskiy). 3. Rukovoditell Sektorom tokbniko-ekonomichaskikh Issledovaniy Veasoyuznogo nauchno-iseledovatel'skogo instituts, novykh stroitellmykh materialov,, Moskva (for BogualavskiY). 4. Wen- korrespoz;dent Akademii stroitellstva i arkhitektury SSSR (for Andreyev,,' Poso~hin),, ---KONSTANTINOVA, M.A., arkhitektor; AYRAPETOV, D.P., arkhitektor Architectural and structural strip products made of polymer materials. Sbor. trud. VNIINSM no.7:127-142 163. (MIRA 17:11) (14-IRA u t Znmgncz, L'A.- ZM2UMWVA, X.le Locomotion wA Ow motor apparatO of Rotifera Cb-ClIsh summery In Insert]. Zsolosbar*35 M90'3:345-364 Mr 156. (=A 9:7) I.Bialoge-pochysaW falulltat Mookovskoge gosuftzeftennogo mdvftsi- tot& Imeni NOT.Lemonosevas Otatifors) 17W AUTHOR: Konstantinova, M, I. SOV120-125-3-60163 TITLE: Motion of the Pelagic Larvae of Heteromastus filiformia Clap. (Polychaeta) (Dvizheniye pelagicheskikh lichinok Reteromastus filiformis Clap.(Polychaeta)) PERIODICAL: Boklady Akademii nauk SSSR, 1959, Vol 125, Nr 3t pp 677-680 (USSR) ABSTRACT: The author refers to papers (Refs 1-7) dealing with the morphology of the locomotor apparatus and the types of motion with the aim of following the line of evolutiona y variations from the low invertebrates up to the higher ones. The author was to continue this cycle in her paper. She restricted her investigations to the determination of the quantitative indices of the velocities of motion in different stages of the larvae mentioned in the title. The numerical data obtained by measuring were biometrically evaluated according to formulae (supplied by N. A. Plokhinskiy). On this basis the empirical curve of dependence of the absolute velocity of the larvae as dependent on their body length was plotted, taking growth and Card 1/3 shape into account. Further, the curve describing the Motion of the Pelagic Larvae of SOV120-125-3-60163 Heteromastus filiformis Clap. (Polychaeta) dependence between relative velocity and body length was plotted (Fig 1). The shape of the newly hatched trochophore Fig 1 a , of metatrochophore (Fig I b) and of nectochaeta g 1 v~ is described in connection with the type of motion M of each of the stages mentioned. In H. filiformis body shape is constantly transformed in the course of the pelagic larval stages, from ball shape to cigar shape, under a simultaneous transformation of the ciliated apparatus. In this connection the larva undergoes a transformation from monotrochous to ditrochous type. The empirical curve describes the increasing absolute velocity of motion of the larvae, The relative velooity decreases from 5 to 2 conditioned units. Thus the relative velocity decreases by more than 50%, while the body length attains almost the four-fold of its former length during the same period. Difficulties arose in connection with comparing the above results with the data obtained by other authors. In spite of all the variety in the structure of the ciliated apparatus it is, however, always possible to discover afeature characteristic of the motion of the aquatic invortebratee; Card 2/3 they rotate around their own axis, mostly in counter-clookwise Motion of the Pelagic Larvae of SOV120-125-3-60163 Heteromastus filiformis Clap. (Polychaeta) direction. This indicates a physiological functional similarity of all ciliated apparatus, independent of their location and structure. After pointing out the differences between H. filiformis, Infusoria, Turbellaria and rotatoria, withrespect to the absolute motion velocity the author arrives at the following conclusion: relative motion velocity and body size are in a reciprocal dependence. In other words, the numerical indices of velocity are in the case of Folychaeta. larvae within the limits of the general laws of motion of groups so different with respect to their morphology as it is the case with Infusoriaq Turbellaria and rotatoria. There are 1 figure and 7 referencesy 6 of which are Soviet. ASSOCIATION: Moskovskiy gosudarstvennyy universitet im. M.V. Lomonosova (Moscow state University imeni M. V. Lomonosov) PRESENTED: December 19v 1958, by Ye. ff. Pavlovskiy, Academician SUBMITTED: December 11, 1958 Card 3/3 '*-- :~.I :i' RUBC100 - the morphogoncois of Hamothoe imbricata , i: (;*!,,- * I'. .. --. C-aeta)~. I. AV SSSR 137 no. 1:232-235 Mr-Ap 161. (Mr, JL 14:2) 1. 1,(- -ovohi, ~ .oaudarstvonW universitet im. M.V. Lomonosova. Yrcdotcivlono "!:~~demiIom Ye.11. Pavlovskim. (I'OIYCA~~.Ota) (Animal locomotion) (Iforphogonesis) kmethod-for-the I f .-T ---- -r . -h-t um on M ~ ~ 1 1, .5 4 ass one g- 0 1 Add 150n "fl distd. Hz(). w.ater b-.~ 'I with Const it;-- coagaiated proteina. While st:'~ cloth and then through filter rrit-- Y.Ft -!wh 1P) ml. of the filtrate udd 35 g. of (N-10 for 12-21) hrs- A tight-brown pj~' :.mt fluid b-~ carrful and ~Io- rrmo~e supernatant fluid as po5sible. Redissolve the plit. viously boiled and cooled to I A da:k-brown soln. Is formed For each 100 ml. add, with Cd,'qO,. I.Ti(hin 2448 hr-3 tenip. Centrifuge fur 1w: m. Sep the supernatant fluid i;!:: 1 pr" i,in, caotiou,ly and com-p!, with the mother fluid and 1, judged to be fret from crystalgindhtti HIO. AEi~lir Rcrnwve the. CdClj. by a Mrre-~L- UM-ee-Orra can etecte-d by ciwm,-~ T, m ef .,. ME'TANTIIMOVA, M.".: KONISTANTINOVA. M.M.- "The effect of ferritin on blood pressure". 1-'Osc(7,21, 1955. Acad Sci USSR. Inst of Animal Morphology irreni A -IN. Severtsov. Dissertations for the Degree of Candidate of Biological Sciendes) SO: Knizhnay letopi I No 44, 29 October 1955. MoscW- USSR / Human and Animal Physiology. Zffect of Physical Factors. T-13 Abe Jour : Hof Zhur - Biologiya, No 1, 1959, No. 3975 Author : Grayevskly, I* Ya.; Konstantinava, M. M. Inst AS UM Title On the Absenco -of a Protective Wluenoe of Hietotoxic Hypoxift 6n,Action of Ionizira Radiation Orig Pub Dokl. AN sm, 1q57,.ll4,, No 2, 289-292 Abotract Suspensions of bacteria Becherichle. coll, which remainod for the duration of I how in a solution of IDN 0.'. '002 m. or for ths.durstIon of-5.- 10 min. In an atmospheft of 95% CO and were subjected In the same medium to IrradiatIon of 1000 - 20,000 r with the strength of thq dose at 500 - 900 S/ndn., were disseminated in agar at 370* After 24 hours, the count of colonies showed that both hIstotoxIc agents, despite the defensive effect ascribed to them, Inhibited the ability of irradiated Card 1/2 P\ D IV 3 1 /7 IT T f T USSR V C A T W 0 R.11 ! Pharmaeolo&ry and Toxicology. Cardlovasoular Agnnts AB^ - JOUR- F210iol-, No- 5 101591 NA. 23200 AUTHM ~~mtantfnova, M. M. TI SIE t On the IWotensive Effoat of Perritin OIRII G. PUB. PaLtol. f iziologlya I oksporim. terapiya, 1958, 2, Yo 4, 33-30 ABSTRUCT 311 ferritin (P) poisessez, a '11-lypotonsivo activity, wbich manifests Its6lf oxUy Do. caue of patholo- gically inarsaaad arterial pre2aure, whteroas an ox4dized F exhlbits no iveh rativity. 7he hypo- tonsj.v6 action of F is manifested in lower doses as c6mpared with other hypotensive agents. Vne eff6et takos place after a latent Deriod lasting 1 40 min +,o'2 houre. Upon repeatod a;WnistraUon of F, the latent period of its action and the. amount by which the presmare decreases are re- C H G : 17 I ID,, j0UP.. KINUol.1 lie. 5 1959.0 N*i. 23200 V AIKHOR INST. TIME OPIG. PUB. A!3::.-".TRACT d1jeed; tb-e 12uration of the period of depressed cont'd pressure increases. F decreases the sensitivity of vessels to adranaliMp both 1-n *isolated organs (kidneys,, rabbitts ear), as we!]. a-- in.aniltials With an increased pressure. a rd: 212 2OV/2o-1 22-3-16/57 On the Antiradiation Protective Effect of Substances 7-lockin,~, the Transport of Hemol-lobin was determined for a time of 30 days. The amount of bin distinctly Crows already 5 minutcs af ter the introdnetion of sodium nitrite, and it reaches its maximum, valuQ '65 40-60 minutes after the introduction of soliur nltrl.n. Th(j content of methemoclobir, this value for 1 - !' i'~ '-ours. A listinct protective effect, of soeliurn nitrite cannot be ol-aerved before 20 minvLen after its introduction into th--~ or.-anism. The maximum of the 1~rotoctive offec"; wag Oboeivod 40 - 60 minutes after the introdution. The period of the Y ium intensity of the protective action corresponds to 'he .naxiL h period of the highest content of met]-temo-lobin in the blood. In the experiments with carbon monoxide, the coincidencs of the curves of the heri-or-lobin inactivation and of the 311--vival rate was still better. A connee t4 on between the quantity of the inactivat,.d, hemoglobin and the intensity of ihe 1,rotective effect was found. The protection due to carbon monoxide ie more efficient. The following conclusion may be drawn from the data discussed in this paper: The izotective effect of the prophylactic introduction of sodium nitrite or carbon - monoxide before and during the irradiation is caused by the Card 2/3 hypoxia due to the suppression of the oxygen transport. There SOV120-122-3-16, ." 5 'T On the Antiradiation Protective Effect of Substances Blocking the Transport of Hemoglobin are 2 figures and 14 references, 5 of which are Soviet. ASSOCIATION: Institut morfologii zhivotnykh im. A. IN. Severtsova Akademii nauk SSSR (Institute of the Morphology of SlAnimals imeni A. N. Severtsov, Academy of SciencesPUSSR) PRESENTED: I.Tay 22, 1950, by A. I. Oparin, Academician 5UMIITTED: may 15, 1958 Card 3/3 240 AUTHORS: Shapiro#,1,. Meg Konstantinoval M. M. SOV/20-125-3-54/63 TITLE: On Chromosome Aberrations and the 11itotic Activity Subsequent to the Effect of Ionizing Radiation Under Protection by Carbon Monoxide (On the Problem of Reparation of Radiation Injuries) (0 khromosomnykh aberratsiyakh i mitoticheskoy aktivnosti pools vozdeystviya ioniziruyushchey radiatsiyey v usloviyakh zashchity okislyu ugleroda(K problome reparatsii lucheyogo povrezhdeniya)) PERIODICALi Doklady Akademii nauk SSSR, 1959, Vol 125, Nr 3, PP 654-657 (USSR) ABSTRACTt Prophylactic application of several substances increases the percentage of survival of irradiated animals and accelerates the regeneration of the injured tissue. Thus, in the case of hypoxy and anory (Refs 1, 2) the number-of chromosome abe=a- tiona decreases after relatively small doses of radiation. The effect exercis9d by the two mentioned factors upon the resto- ration of the capacity of cell division is, howeverp still insufficiently investigated. This is the reason for the interest in the investigation of the accelerated regeneration of tissue (which is probably connected with the higher Card 1/3 porcentage of-ourvival)' in animals irradiated with a fatal- On Chromosome Aberrations and the Mito 'tic Activity SOV120-125-3-54163 Subsequent to the Effect of Ionizing Radiation Under Protection by Carbon Monoxide ( On the Problem of Reparation of Radiation Injuries) dose under protection. It isthe aim of the present paper to investi-gate the ways of action of a group of substances the mechaniscof effect of which is brought into relation with the "oxygen-effeot".,In this case carbon monoxide was concerned. In the 3 experimental series mice were irradiated with: I J1117r.ays from'Co 60 (dose 900 r, intensity of the dose 595 r/min)- 11.-15 minutes before irradiation the mice were exposed to an atmosphere with Oi,5% by volume of CO. Under those conditions the blood of the mice contains 72% carboxy hemoglobin'. After 30'days 25% less fatal cases occurred as compared to -100% in control (Ref 3). 111. Mice were kept in a similar atmosphere with CO for 17 minutes but not irradiated. After 10 hours all experimental animals were killed and the mitoses in the cornea-were counted with respect to the chromosome aberrations. tables 1 and 2 show the TeBUltS. They reveal that towards the 8th day after irradiation (which corresponds to the average duration of life of the animals in the I. series) the number of the formed~ cells amounted in the Card 2/3 case of those in hypoxy to three times the number of those On Chromosome Aberrations and the Mitotic Activity SOV/20-125-3-54/63 Subsequent to the Effect of Ionizing Radiation Under Protection by Carbon Monoxide (On the Problem of Reparation of Radiation Injuries) animals that were not protected. There are good reasons for the assumption that the differences in the intensity of regeneration comprise also the bone marrow, intestines, skin and other organs (Ref-7). Thus, it is possible to explain.the increased number of surviving animals protected by CO which is due to the utilization of protective substances causing the state of hypoxy during irradiation. V. Yu. Urbakh assisted in the discussion of the work and the statistical evaluation of the experimental results. There are 2 tables and 7 refer.onces, 3 of which are Soviet. ASSOCIATIONi Institut morfologii zhivotnykh im. A.N. Severtsova Akademii nauk SSSR (Institute of Animal Morphology imeni A.N. Sever-bsov of the Academy of Sciences, USSR) PRESEUTED: December 4, 1958, by I. I. Shmallgauzen, Academician SUBUTTED: November 28p 1958 Card 3/3 8142:0 9/020160/13e-/06/57/068 B0111BOO3 41-7,900 AUTHOR: onftantiuoxu~' M. TITLE: Tissue-EUrpoxia as a Mechanism of the Anti-radio Protection Jq Effect of Adrenaling Heroing and Morphine PERIODICAL: Doklady Akadsaii nauk aSsR, 1960, Vol. 132, No. 6, pp. 1427 - 1430 TEXT: By way of introductiong the author discusses the hypothesis of protection against radiation by a lack of oxygen in cells and tissues. The three neurotropic alkaloids mentioned in the title are looked, upon tl~ as the strongest protectives against radiation. Experimental verifica- tions of this mechaniamp howeverp are missing in the data available. The author intends to solve this problem in the paper under review. Since only the "hypoxio" concept of the mechanism of protection is well-founded, the author studied the problem as to whether the protective effect of neurotropio substances is in connection with their ability to reduce the oxygen tension in tissues. For this reasong he studied the influence of all three alkaloids on the oxygen tension and their protective effect. Card 1/4 8WO Tissue 1.3ypoxis, as a Mechanism of the Anti-radio S/020V,60/132/o6/57/068 Protection Effect of Adrenalinq Heroin, and BOII/ n,003 Morphine White mice were used as experimental animals. The 02 tension in the tissue was determined polarographically in vivo. A ohlorine-silver eleo- trode was used. Since the method employed does not permit to determine the absolute 02 content, the recorded current was expressed in per cent of the initial level. The author ascertained the change in the content of 02 in the liver, miltq and muscles after a hypodermic injection of 0.1 mg of adrenalin, 3 mg of heroin, or 1.25 mg of morphine in 0.5 ml of distilled water pe; animal. Other animals were simultaneously subjected to yo-radiation of C000 (dose 900 r, dosage 450 r (min)) for 2 min at va- rious points of time after introduction of the substance mentioned. The survival of mice for thirty days was regarded as a criterion for the efficiency of protection. Next, the author compared the change in radia- tion sensitivity with the change in 02 tension as dependent on the period passed between introduction of the protective substance and ir- radiation. Table I and Fig. I show results from which it follows that the 0 content was considerably reduced in the tissues by the substances 2 Card 2/4 M20 Tissue Hypoxia as a Mechanism of the Anti- S/020/60/132/06/57/068 radio Protection Effect of Adrenalin, Heroin, BOll/BO03 and Morphine ASSOCIATIONs Inatitut MOrfOlOgii 2hivotnykh im. A. V. Severtsova Akademii nauk SSSR (Institute of Animal Morphology imeni A. N. Severtsov of the Academy of Sciences, USSR) Ll PRESENTEDs February 6, 1960, by A. I. Oparin, Academician SUBMITTED3 FebruarY 4, 1960 Card 4/4 82526 S/020/60/133/04/30/031 B016/BO67 AUTHORS: Grayevskiy, Ye. Ya Konstantinova, M. M.- TITLE: Study of the Mechanism of the Radioproteotive Action of Some Sulfur Containing Substances PERIODICAL: Doklady Akademii nauk SSSR, 19609 Vol. 133, No- 4, pp. 969-972 TEXT: The authors present five hypotheses on the radioprotective effect of some sulfhydryls and some thiuronium compounds which are structurally related with them. These substances are one of the most effective radio- protective substances. The data of publications do not allow the esta blish- ment of a connection between the radiation resistivity of an organism and the state of its regulating systems. The protective effect has approximate- ly the same degree in biological objects at different stages of development. The authors mention further inadequate explanations of the protective ef- fect (Refs- 11, 15). The assumption that the protective effect of sulfur containing compounds is due to the so-called "oxygen effect" (Refs. 10, 16-25) is the most probable. In conclusion, the authors state that the Card 1/4 82526 Study of the Mechanism of the Radioprotective B/02--'0/133/04/30/031 Action of Some Sulfur Containing Sub3tances B016rBO67 hypothesis according to which the protective effect of the substance con- cerned is based on the anoxia in the organismg that it is also based on rather contradictory data, and that it must not be regarded as proved. The authors wanted to explain the role of the level of molecular oxygen in tissueB for the protective effect. For this purpose they used grown-up white mice. The above-mentioned affect and the oxygen tension in the liver and the spleen were studied at different periods after subcutaneous injec- tion of the following compounds: oysteaming cystaming Br.HBr-2-aminoethyl isothiuronium (AET), Br.HBr-2-amino-5-isothiuronium-mothyl-thiazolin (AIMT), furthermoreq RCl.eystaine and SH glutgthione. The animals were once totally irradiated with gamma rays of Cc 0 (dose: 900r; dose intensi- tY: 378 r/min, for 2 min 21 seo).Qhey were irradiated 15, 30, 60t 1209 and 180 min after the injection. The duration of life was observed within a period of 30 days. Table I shows the number of experimental animals. Fig. 1 shows the results obtained with oysteamin. This substance has a considerable protective effect; it does, howeverg not reduce the 02 content, but increases it in the spleen. Fig. 2 shows that also cystamin does not reduce the oxygen tension duTing the duration of the protective effect. Card 2/4 82526 Study of the Mechanism of the Radioproteotive S/020/60/133/04/30/031 Action of Some Sulfur Containing Substances' B016/B067 In introducing AET 15 min before the irradiation the protective effect becomes distinctly marked (Fig. 3 A). The 02 content is only slightly reduced. Analogously, AIMT has a weaker effect on the 02 level; its pro- tootive effect is also much weaker and only of a short duration (Fig. 3 B). Cystein (Fig, 4) and SH gluthathione tension hardly change the 02 in both organs, they have, however, a considerable protective effect. From these results the authors draw the conclusion that the protective effect is not caused by tissue hypoxia. At the same time it is assumed that the effect of the above-mentioned protective substances is, nevertheless, connected with the "oxygen effect". Henceg it may be assumed that this effect is not necessarily connected with the radiolysis of water. Perhaps, it may be explained by the formation of potential disturbances in biological objects, which may take place only during the oxidation by molecular oxy- gen. In this caseq the protective effect of the substances under considera- tion can be related to their capability of preventing the oxidation by molecular oxygen.of thellstructures" damaged by radiation. The authors thank V. M. Fedoseyev for the synthesis of AET and AIMT. There are 4 fig- ures, I table, and 27 references: 7 Soviet, I US9 3 Intern. Conf.9 and Card 3/4 GRAYEVSKIY, E.Ya.; XONSTANTI110VAp M.M. Radiation protective effect of some agents And the *oxygen effect.' Radiobiologiia, 1 no*2:270-277 161. XU 14:7) 1. Institut morfologii sUvotuykh imeni A.N.Severteova &N SSSR, Moskva. (RLDIATION PROTECTION) (OXYGEN-PHISIOLOGICAL EFFECT) S/205/iol3YO6(01/005/001/005 -A D299/D3o4 AUTHORS: E.Ya. Grayevskiy, and_MM _XQzxjAntino'v'a TITLE: A study of the mechanism of the protective action of ami- noethyl-isothiuronium on rats irradiated in a state of hypothermy PERIODICAL: Radiobiologiya, v. 1, no. 5, 1961, 650 - 652 TEXTs The lack of defensive action from oysteine after irradia- tion in animals with a normal metabolism and its presence in chilled hy- bernating animals tends to indicate that protective compounds, if at all capable of weakening the radiation reaction when introduced after irradi- ation, can only do this when the development of the radiation reaction is strongly inhibited. To check this assumption a study was made of the pro- tective effect of aminoethyl-isothiuronium (AET) Br.HBr. on animals irra- diated in varying states of hypothermy. The experiments were conducted with white mice exposed to single gamma-radiation from a c060 source in a dose of 900 r (LD 100/15 ) at an intensi-ty of 320 r/min. The body temper- Card 113 W A study of the mechanism of ... 30366 S/20 61/001/005/001/005 D299YD304 ature of the mice at the time of Irradiation in the three test groups was 37, 18, and 60 C. The protective agent was injected subcutaneously at 9-10 mg per mouse in 0.05 ml of distilled water 15 min before irrad- iation or 10 - 20 see after it. The number of animals that survived for more than 30 days after irradiation and the life span of those animals which died beyond this period was taken as the criterion of the effect- iveness of AET. The results showed that prophylactic injection of AET into mice with a body temperature of 370 C gave a marked increase in the survival rate of the irradiated animals and increased the average life of the animals which died. The propylactic affect was lower in mice with a body temperature of 180 C. At 60 C no protective action was not- ed, due perhaps to disturbance of the resorption and admission of the AET to the radiation-sensitive systems or to inhibition of its conver- sions. The AET was ineffective in all cases when introduced after irra- diation. The authors' findi onform to those of D.E. Smith (Ref. 5' Radiation Res., 12, 79, 19601swco found that the administration of cy.- steine after irradiation to animals of the genus Citellus irradiated in a state of hibernation with a body temperature of 150 C had no protective Card 2/3 21.ooo AUTHORS: TITJJE: 20366 S/020/61./136/005/032/032 B103 B208 Grayevskiy, E. Ya, and Konstantinovat M. M. -------------- Mechanism of antiradiation effect of dithiols PERIODICAL: Doklady Akademii nauk SSSR, v. 136t n06 5, 1961, 1219-1222 TEXT: The authors studied the antiradiation effect of dimercapto compounds: 1) of unithiol. and 2) of dimereapto propionic acid (DMPA) on white mice. They compared the efficiency of these dithiols with the hypoxia caused by the latter (due to oxygen teneion). There are only few contradictory drLta available on this problem. The mice were totally irradiated with y-rays of Co6o with a dose of 357 r/mino and with an absolutely lethal dose of 900 r, once for 2 min 28 see. The mentioned protective substances were injected subcutaneously in 0-5 al distilled water in the following quantities- unithiol. 20, 14, and'g, DMPA 1.0 and 0.75 mg per animal. Unithiol was applied at 11 intervals between 10 and 180 min. DMPA at 6 intervals between 15 and 180 min prior to irradiation. The criterion of the efficiency was the percentage rate of the surviving animals, and the lifetime of the killed animals up to Card 1/6 20366 S/020/61/136/005/032iO32 Mechanism of antiradiation effect-... B103/b2O8 that the protective effect of dithiole is probably due to hypoxia caused by these dithiols in organs sensitive to radiation P in contraet with the effect of the best -known sulfur-containing compounds (p-mereapto ethyl amine, or 2-aminoethyl isothiuronium-B-HBr, etc.). The formation mechanism of this hypoxia could not yet be*explained. There are 2 figures and 8 references: 4 Soviet-bloc and I non-Soviet-bloc. ASSOCIATION: Institut,morfologii zhivotnykh im. A. N. Severtsova Akademii nauk SSSR (Institute of Animal Morphology imeni' A. N. Severtsov, Academy of Sciences, USSR) PRESENTED: August 22, 1960p by A. 1. Oparin, Academician SUBMITTED: August 18, 1960 Card 316 23818 ~a/co 1/02 B 10'-/'B20r, AUT.40R. Ycnutantucvmi, -t of lowerlnp-, ~!-)e "QJY telr,'Pe-"at~re, TITLE; as a ra;~64- PEFINDICAL: Dc klad y At, -ad e m inauk SSSR, 5. 1 ,9-- 2 -12 TEXT: The au t ho r -?x-c la 1 n s tn e q-.~,i z, ~%,n asori~ f -,J e r t he r cet i ve Q diation is due tc d).rc-,t temy%~rat.ir,,~ It was, it-, part,J,,tul.ar, r:ct n't-ar. 7vti-rn-r rhir t~ffeo,~, a z3on3equen,--,i~ of therm-, a Tc, ar~ 0. 11"a a..] thcr !~;rljrj I-Itl .1 e ~- f f e -1 t ac,-.-.vr~ng th~ bod-, "I'li cxyg~-,r. "C' tensict- in liver and spleen -.111-h thE ra S iffe-:t of th!i corresponding w -a C d;,r,?rm..Ln~d z~n cool -ng wi~hcnttrd I 1 0 t E .i r e 9 us 23818 I 3,J/CO 1/02-3/02 5 Rad ;.a ' 3. o n -pro te c t i %,4~ o f f q o of B '0 t e ii _9.'~, a r., -I v a I ra"-- 0 2 J a P I 1 70 a q Zl 0, 0 MT~ i. ,z I 7 r ami ra;.,. ine . th e an.zm. - 'jv~, p,) i ~i f r'~ !-,I Tit tal 1 -L t-I - 4:~,mp~-raf-.~re wao I 7~ y Ice t! --V temloeratiro ~i r -mal temcera-tui- ;r a r i~~ r d ~a 7~7.24 ~:11 WI, ',11 L i'~,g wat er ac.,j f dr*' rel. trat i c r. ?r a ru Y- r ei 7, e r, r -1 y e rha.; J 1(0 r 'min. 41 As the ~~riterit:!j e ~; s i t iv il- Ij :~ervad tne .i r v -L a ra-e v; i r 50 days .. t *-e oar, P t ~ , - A t'. ci 0.1 t P- r. ~; i o t i was Liz- mAred C: ~ r, L II y cther m. e . T~e cathodz waj a PIati--lim e~e~.,,trcde of ~Lp, type. tile anode -q silver chIcrid,! -q c c c R e f . 2 d T"'.Cse M_Lce Vere- given ami-azine as menticned abore after Jos-rtloc~ of ~na e- 'rcdes, and were pi,t into i-ce until. the de3i'red tem-cera-ures were atta-.-1.-Iiid. To judge Card 2116 23818 S/020/61/138/001/023/023 Radiation-proteotive effect of... B103/B208 increases. A pronounced prot,,!:,tive effect became manifest only from a 50 % reduction of 02 tension in 'the tissue onwards. It is important that even on considerable temperature drop the protective effect is comparatively small. For at normal body temperature, even a low hypoxia is an effective protection, irrespective of its origin (Ref. 24). This discrepancy might be the result of a damage of the organism caused by low temperatures (see above). The comparatively low survival rate may be due to a slumma- V1 tion of radiation and hypothermia effects. Considering the actual effect of cooling alone, the protective effect approaches that in animals with normal body temperature. The protective effect of cooling in warm-blooded animals is thus due to the accompanying hypoxia which may be the result of a more intense suppression of 0. uptake than it is the case in the oxidation processes in the tissue. This is also the cause ofdeath of cooled warm-blooded animals. In cold-blooded animals, on the other hand, which are adapted to low tomporaturea, the 02 metabolism is not disturbed by hypothermia. In these animals, hypothermia will not exert a protective effect. There are 1 figure and 25 references: 5 Soviet-bloc and 20 Card 4/6 GRAYEVWSKIY, F.Ya., KONSTANTINOVA, M.M. Independence of the radiation protective action of aminoethyl- isothiuronium - Br -`HBr from the "oxygen effect." Dokl. Ali SSSR 140 no-3:705-708 S 161. (FURA 14:9) 1. Institut morfologii zhivotnykb im. A.N.Severtsova AN SSSR. Predstavleno akademikom N.M.Sisakyanom. (Pseudourea) (Radiation protection) ImesilgalJorri on Radialign Protective WMAmarals E. Vq G4.11Y. N. P. Barakina. M. ht. ,eonitantintra and 1. 13. Smir"ra 10diation protectors varying in their structure and physiological effect can be divided by their ro-hanhor of protective action Into two xroup~ One C-up Act% by -U,i.g 16". hypo.ia, while the proiNtive action of the world group firpean not to tv MAW to the Plygra CITCCI. Protectnt-s ofthe second groupshow acicar morphological protection oranimat, exposed to radiation. d"33ing the daniage to the intestine and hictirtopoictic timuci. Under the action of an example or this group. amino~ ethylkournitium-ONIM (AIM, repair proomics are acev4-tvI. and !,ever chmmot("JI aberrations are seen l i h i r and the ability ofcells to undergo division is restored. although them 6 no dim on in t e in tial number o ca, nut of the intestinal crypts disrupted as a result of irfadi3tion. Ilacrnopoictic 0%;uc, Irradiated in the prttence, of AET. sh-re a greater number of Intact ails And reirencradco 13 greatly at,"Ictated. .7he Interaificalion of repair processes observed In radiosensitive fisititi immi to be dtictminctl by a smaller initial damage of their component ccliulcr elements. 1-1-.WAd-d Aff4d-sy. A,&kj, ofSdows flAO USSR, Af~. "I)Or't J)"Barlattld at th& 20A Xrjtj. COISMItIS of pad"tj= j*Gt,,XCh, 5-U AUS 19U 39 89 51020162 145/002/017/018 B1 44/B16G Konstanti ova, M, TITLE: Effect of the duration of moderate hypothermia on the 0 2 pressure in the tissues and on the radiosdnsitivity of mice PE.RIOZJICALz Akademiya nauk SSSR. Doklady, v. 145, no. ?, 1962, 436 - 437 MEXT: 0 Groups of inice were kept for 30 and 120 min. at a rectal temperature of 18 C; then: (a) the 0 2 pressure was determined in liver and spleen and 0)) the 'radiosensitivity was studied after gamma irradiation with 900 r. The author's methods of hypothermia and polarographio determination of the 02 pressure have been described previously (DAN, 1389 no- 1p 223 (1961)1 DAN, 132, no. 6,.1427 (1960)). a) The 0 2 pressure was reduced in both orcans by -4Z, irrespective of the time of hypothermia. b) The radio- sensitivity was judged from the-average life of mice dying within 30 days and from the survival percentage. The former increased from 6.1 in the- control animdls to 9.0 and 9.5 days, the latter from 0 to 15 and 7~. Thus, Card 1/2 Card 2/2 'Z7. ~kO 0 4161~0 S/20&/'62/002/004/014/014 1015/1215 A WITH OR 5 Zeytunyan,K.A., Konstantinova.M.-M- ahd Semenov,L.F. TITLE: The effect of certain.antirndiation agents on the oxygen level In tissues in relation with their effect on the radiosensitivity of animals PERIODICAL: Radlobiologiya,v,2, no.4, ~.962, 616-619 TEXT: This is the continuation of a previous stu.d7,, The experi- ments were carried out on albino mice of both sexes, weighing 18-20g. Adrenalin (0.02mg/mouse), acetyleholin (0.6mg/mouse), tryptamine (1.5mg/mouse), sarotonin (0.5mg/mouse), phenylethyl- amine (O.Sng/mouse), thiourea (45.0mg/mouse) and aminoethyliso- thiouracil (AET) (3.Omg/mouse) were injected s.c. in aqutLeous . solutions,, The oxygen tension in liver and spleen was determined -polarographically, The effect of these substances on the oxygen tension was different for spleen and for liver, and varied also with each substances Acetyleholin brought about the mo-st marked Card 1/3 j S/205/62/'002/004/0.14/014 1015 1215 The effect of certain Rntiradlation... Pathology and Therapy, AYIS USSR, Sukhumi) SUBMITTED: February 13, 1962 1 Card 3/3 GRAIEVSKIY, E.Ya.i XONSTANTINOVA, M.M. Dependence of the radiation protective efficiency of various substances on the oxygen content of tissues and inhaled air. Dokl.AN SM 245 no,1:195.-197 JI 162. (MMA 15:7) 1. Institut morfologii zhivotnykh imeni A.N.Severtsova AN SSSR. Predstavleno akademikom N.M.Sisakyanom. (RADIATION PR=TION) WMEN) KOBSTANTINOVA, , -- Qxygen tension in the tissues and rediosensitivity of mice as dependent on the duration of *derate hypothermia. Dokl.AN SSSR 245 no.2:436-1+37 JI 162. (MMA 25:7) 1. Institut morfologii ahivotnykh imeni A.N.Severtsova AN &96R. Predstavleno akadevaikon N.M.Sisakyanom. (HUMHEMak) (GAMVA RLYS-PHrSIOLOGICAL EFFECT) (CKYGF.N IN THE BCDX) GRAYEVSKI7, E.Yk; BARAKINA, N.F.; KONSTANTINOVA,, M.M.; SlUB210VA, I.B. Studies on radiation protection in -amols. Zhur. ob. biol. 24 no.3:182-193 My-Je'63. (101A. 16x8) 1. A.1f.Severtzov Institute of Animal 1-brphology., Academy of Sciences of the U.S.S.R.r Moscow. (RADIATION--PROrECTIVE AGENTS) GRAYEVSKIY, F.Ya.; KONSTANTINOVA M.M., WKRASOVA; I,V.; TPRA.---P*NKO, A. G. - Mechanism of the radioprotective action of cystamine (2-aminoethyl- disulfide). iladiobiologiia 3 no. 6t8gl-897 16L (MIRA 170) L Institut mor"clogli zhivotnykh imeni A.N..~.evertsovu AN SSSR, Moskva. ACCESSION NR: AP4027966 S/02o5/64/oo4/oo2/olq7/o2o2 AUTHOR: Grayovskiyo E. Ya.; Zherobchenko, P. Go; Konstantinova M. k,.; Sokolava, 0, M,; Shevchenko, A, No TITLE: Relation of ridioprotective -activity of indolylalkyl. amino a t04 tissue hypoxia and the role of vascular changes in its development SOURCE: Radiobiologiya, v, 4. no. 2, 19648-197-202 TOPIC TAGS: radioprotoctive action mechanism, indolylalkylamine radioprotective action, tissue hypoxia, vessel spasm, tryptomine derivative, radioprotective preparation, 4-,5-chlortryptamine, 4-,5-raetoxytryptamine, serotonine, alpha-methyltryptamine, LSDO cystamine, oxygen intensity. cystamine radioprotective action ABSTRACT: Literature studies have established that indolylalkylamine radioproteotive action is related to tissue h7poxia. This work investigates the mechanism of this action by determining 1) v~ether I 'its t he position of a substitute in a tryptamine*molecule affects capacity to produce tissue hypoxia, 2) how - the introduction of alpha-methyltryptamine and LSD affects the hypoxic- and vasoconstriotive Cardl/3 ACCESSION NR: AP4027966 .action of the preparationso and 3) how the combined use of 5-matox-ytryptamine and eystamine affectsoxygen level and vessel reaction in tissues, The following preparations were administered intraperitoneall7 to experimental white mice: 4-chlortryptamine (6o ma~kg), 5-chlortryptamine (60 'F/W, 4;metoxytryptamine (60 ril.,,il~le),5-nc'v-oiAryptamine and arotonine (50 mg/l~g) i hr' after administering alpha-mothyltryptamine, aystaxnine (150 4/kg) comoined with metoxytryptamine (50 iig/kg), and LSD (10 rr~/kg) combinod*with serotonine. Oxygen intensity in the liver and spleen of' the anima3z vas measured by a polarographic method. Vessel tone was determined by the accumulation of neutral red in the organs 30 min after being introduced (65 mg/lcg in a0-5 ml physiological solution). Findings show that tryptamino derivatives with substitutes in the fifth position (5-metoxY-, 5-chlortryptamine) are highly effective radioprotectors because of their capacity to produce hypoxia in radiosensit-ive organs by vessel spasms. Tryptamino derivatives with substitutes in the fourth position (4-chlor-, 4-motoxytryptamine) do not produce hypoxia or vessel spasms and are ineffective radioprotoe- t.ors. Alpha-methyltryptamine and LSD remove the radioprotective effect of indolylalkylamines by,preventing the development of vessel spasm and subsequent tissue h7poxia, Oystamine enhanoes the C,,d 2/3 ACCESSION XR: AP40279&6 radioproteetive action of tryptamine derivatives,, but does not affect; their capacity to constrict vessels and to develop hypoxia, The radipprotective action mechanisms of eystamine and the investigated indolylalk7lamines differs Orig. art,.has: 4 figures, 2 tables, ASSOCIATION: None SUBMIMTED. o6APr63 DATE ACQ: .28Apr64' EXCL: 00 SUB CODE: A14 NO REP SOV:' 01~ OTHER: .008 ,Cord3/3 .ACCESSION NTR -A7r4_62 7 0 6 9 S/0~05/64/00h76W&Wo 0 080yevo V, M. JAUTHOR: Konstantino.va, M. M.; Tarasonlco, A. a.; Pad TITLE: Investigation of the antiradiation activity of N-allcyl ,--derivatives of 2,,3-dimeroaptopropylamine and their action roachanism ~SOURCE: Radiobiologiyat v9 4. no, 2. 1964, 216-22o ii'TOPIC TAGS: radioprotective action mechanism, dithiol Group, ;ill-alkyl derivativeg 2,3-dimarcaptopropylamineg synthetic N-alkyl it .:4derivative, oxygen Intensity,, tissue hypoxia, dithiol'!Vadioprotective'~ !Naction, meroapto., gamma radiation, lethal dose, radiation siolcaess, :,increased radioresistance I!ABSTRACT: This study investigates the N-alkyl derivatives of 1120-dimercaptopropylamino, there being little data in the literature ;Io4 the radioprotective action of substaneds-containing sulfur es'pe cially the dithiol.groups, These derivatives, synthesizei ior :ithe first time by the authorap were studied in relation to their p ;effect on oxygen intensity in the tissues. Experimental white mice .,;were gamma-irradiated (0000$ 270-280 r/min) with single 900-r doses , hrrd- C L 3452-66 EWT(m) ACCESSION NR- AP5024008 UR/002016~/164/002/0441/0444 AUTHOF,: GXgygvskiy,. 1q, a.; Konstantinova, M. M. Sokolova, 0. M. Tar_ap-qp1(o,_A. G. TITLE: On the common mechanism underlying the radiation protective properties; of aminothiols and anoxia SOURCE: AN SSSR. Poklady, v. 164, no, 2, 1965, 441-444 TOPIC TAGS: radioprotective agent, reaction mechanism, tissue physiology, anoxia, organic sulfur compound ABSTRACT: The work attempts experimental verification of the hypothesis that the basic mechanism of these radioprotective effects is related to an increas eId level of free sulfhydryl groups in the tissues. White mice aged 8-12 weeks were irradiated with 900 r (LD100/30)'and were kept in glass containers to facill-I tate change of air. The following aminothiols were injected subcutaneously Is- I --" 30 minutes before irradiation or before sulfhydryl group determination: cysL M'- ;i ine, cystamine, 0 -mercaptopropylamine, and sevotonin. . Radioprotection was determined according to survivil beyond 30 days. A spleen homogenate was r sulfhydryl determination with mercuric chloride under argon or air. It SIS L 3452-66 ACCESSION NR- APS024008 was found that all the agents which have a radioprotective effect caused considera- ble (10-351o) increase (compared to control levels) of the groups in spleen homo- genato under argon. Some increase of sulfhydryl groups in air was seen only for, cystaniine. If the mice breathed oxygen immediately before and during irradia- tion, the aminothiol radioprotective effect decreased somewhat, as did the content in the sulfhydryl groups. This was shown to be unrelated to inactivation through 1i oxidation of the protectant. It is concluded that the predominant mechanism of ;1 radioprotection is related to an increase, of highly reactive endogenous sulfhydryli groups, due probably to lesser oxidation and s .pontaneous reduction of the S-S bonds. These appear to be highly mobile groups in low molecular compounds i which are inactive products of radiolysis of the biomacromolecules. Orig. art. has: 3 tables ASSOCIATION: Institut morfologii zbivotnylth im. A. N. Severtsova Akddemii nauk SSSR (Iqstitute of Animal MorphologL Academy of Sciences SSSR) SUBMITTED: 15Mar65 ENCL: 00 SUB CODE: LS NR REF SOV: 007 OTHER: 009 V r' ccrd2/2' 33115 3/638J61/001/000/042/056 B108/B136 d AUTHORS: Kionstantinova.-M. Myakinin, Ye. V., Romanovp A. M.p Teareva, T. V. TITLE: Angular distribution of protons from C 12 (app)N15 with 14,5-Nev alphas SOURCE: Tashkentakaya konferentsiya po mirnomy ispollzovaniyu atomnDy energii. Tashkent, 1959. Trudy. v. 1. Tashkent, 1961v 262-267 TEXT: A study of the angular distribution of protons from (app) reactions may give insight into the direct interaction between alphas and nucleons. The authors studied the C 12 (avp)N15 reaction with alpha particles of an energy of 14-5 Rev, obtained from the cyclotron at the Physicotechnical Institute (gee Association entry). The target consisted of a gold foil (0.25 mg/cm9 covered with a thin layer of carbon black. The differential cross section of the above reaction with N15 in the ground state was determined from the histograms of the proton tracks (Fig- 3). The overall error was about 10%. Experiments with a carbon target without gold Gard 113 33115 8/63-1'1/001/000/042/056 Angular distribution of protons ... Bloe7Bv 138 ASSOCIATION: Fiziko-tekhnicheakiy.inatitut AN SSSR (Physicotechnical Institute AS USSR) Fig- 3- Angular dist!Cibution of protons from C12 (aqp)N 15 at alpha energy 14.5 Mev. Legend: abscissa - differential reaction cross sections.. (1) Calculated, (2) experimental. 6 -012(dP) N Card 3/3 49 69 190 IM 1241 MV V~ TSAREVA9 T.V.; RMWTq A.M.1 22 , 15 9 (O(pp)N reaction of 13s6 Merv. alpha particles. Isy. AN Us. SSH. Fls.-4". nauk .. - (MPA 14:3 ~ 1. Irizag-tekhnicheskiy institut AN SSSR. (A.Ipba rays) Ouclear reactions) ROMANOV, A.M.; MYAKININ, Ye.V.; KONSTANTRIOVA, M.P. leve3z excited in the reaction F-19 (Q~ p)jje22. Izv. AN SSSR. Ser, fiz. 25 no.9:1135-1137 161. (MIRA 14:8) 1. Fiziko-tekbnicheskiy institut All SSSR. (Neon-Isotopes) (Nuclear reactions) KOWTANTINOVA, M.P.; MILKININ, Ye.V.; ROYANOV,, A.M.; TSAREVA, T.V. Elastic scattering of 10 - 15 mov.c(-particles on gold and almims - O.Zbur.ekop.i teor.fiz. 41 no.149-51 Jl 161. (KMA 14:7) L ~enizgradskly fiziko-tekhnicheskiy inatitut AN SSSR. (Alpha rays-Scattering) (Cyclotron) ROMILNOV., A.M.; MIAKININ, Y&*T.;- KOHaTANTI=Aj, M.P. Excited lavelm of N~22,0 Zhar.a"p.i toor.fiz. 41 noel:64-65 J3. ~161. 1 (MIRL 1437) 1. Leningradskiy fiziko-telchnicheskiy inatitut AN SM. (Neon-Isotopee) (Nuclear reactions) (Frotono-Spectra) B102/B104 AUT.,40RS: Konstantinova, 14. P., Yyaklinin, Ye. V., Petrov, A. L1.1 '-9-ozianov, T IT"L E': -Anoular distributions of protons from L,-))-reactions induafza -15 by alpha particles of 13 .'Lev T PERIODICA~ Zhurnal eksDerimentallnoy i teoreticheskoy fizi;V-64.i., v. /r)'~ no. 2(a), 1962, 388 - 393 TEXT: To study the mechanism of (cxp) direct interaction, the --u~hors determined the energy and angular distributions of Dro-6ons from z.'-.e 22 30 reactions Li 6(a,P)Be9, Li7(a,p)B.'O, F19(cx,p)Ne , and .1127 (0c, P) Si at 4, a E - 13-15 Y'ev. The experimental arran-ement was the same as ~h t do- 0: U scribed in ZhZTF, 39, 1540, 1960. The charged particles were recorded by -2 (Ya-2) nuclear emulsion plates. The plates were arran=ed so as to comprise.the angle intervals 10-50, 50-90, 80-140, and 130-1700. T.1 t'-a 11 c.m.s. all angular distribution cu--ves 6(Q) shov,: 11 ) sevcral maxima and Card 1/2 S/056/62/04'3/0&2/006/053 Angular distributions of protons ... B102/'BI04 0 an incr,~;.~SQ of C minima; (2) asymmetry rith respect to 9 = 90 ; and (3) 1 for lar.-e proton emission angles (Q > 1200). These resuit~: aEree -i,-Jth th-ose of analogous reactions at E - 18-40 Mev. The characteristic features o-f the a(G) curves indicate the importance of direct intefaction between nucleus and u-particles. The residual nuclei of the reaciiot's 19(U,P)Ne22 127(U,P~Si3o at E - 13-15 IMev are --ai~ly in the exc-1;ez: F and A C4 I- - 4 A. i.~ 6 91 is V state. The intensity of the p0 proton group (Li (U,P)ue 22 121(., less than that of the p, and P groups A .2 19 p angular distribution of the F reaction does not contfadict tha 2 92 assumn.tion that the second excited level in Ne- is*a 2' level. Thera are 6 figures. ASSOCIATION: Piziko-tekhnicheskiy institut im. A. F. loffe Lkade!mii n.--ak SSSR (11hysicotechnical institute imeni A. P. !Offe o-f the Acadeimy of Sciences USSR) SUB,~.',ITTED: February 23, 1961 Card 2/2 S/903/62/000/000/005/044 B102/B234 AUTHORS: Tsareva, T. V., Romanov, A. M., Myakinin, Ye. V., tant n ~o va ~11. TITLE: The (a,p)-reaction on carbon and the anomalies arising at a-particle energies of 10 - 15 Mev' SOURCE; Yadernyye reaktaii pri malykh i arednilhenergiyakh; trudy, Vtoroy Vaesoyuznoy konferentaii, iyul' 1960 g. Ed. by k.,S. Davydov and others. Moscow, Izd-vo AN SSSR, 1962, 123-132 12(c('p)N15 was investigated with the aim of determining TEXT- The reaction C V the role of the various possible mechanisms of direct interaction and the 27(a,p)Si3o in order to obtain data on the high energy levels ol"' reaction Al Si30 and on the role-of the direct mechanisms in S13O formation in the ground- and first excited states. The.experiments were made with the a-beam of thel cyclotron of the FTI AN SSSR with 100-p '1-2 (Ya-2) emulsion plates and targets enclosed in a spherical brass chamber (500 mm, diam). The angular distribut ion measurements were made in the intervals 10-50, 50-90,'80-140 12 and '130-1700 (lab system).. -,-The proton angular distributions for. the C (a,p) 1/3 - ;19031621000100010051044 r on on... B1 The (a,p)- eacti 02/B234 reaction were made with soot targets on 0.25 mg/cm. gold foils and a 120p Al~ filter whioh served for eliminating the elasticity scattered alphas and the'. 15 tio :of N nuclei in excited states proton groups' corresponding-to forma n The exDerimental results are compared with theoretical considerations based:. on the -formula for da/dAderived by Auistarn et al. (Phys. Rev., 92, 350, 1953), the wave vector of the recoil nucleus is determined from the masses and the w-ave vectors,of the particles involved. The theoretical curve ly ribution measured. 30 levels~- the angular aist' .;.,described qualitativel The Si ~-~-_'excited in (a,r) reactions, are determined and compared with published data (Proc; Phys. So 73i 793t~:1959; Bull. Amer. Phys. Soc., 1, 280, 1956 Pbys.. Rev., 76, 624,.1949).' The results,are given in the table. Also the 27(a,P)Si3O ;:~,angular distribution of the protons f rom. the reaction Al was -2 determined; the Al target- foils were 0.5 mg/cm thick and were exposed to Iong 0 -time bombardment. The reaction orose section in the interval 40-120, j was alm'oat indenendent of~the angle and lay between 15 and 20JAb/steradian. 14.7 Mev)._The shape of the angular distribution in the interval 0 Ihe distribution 50 140 was only weakly dependent on~E i Card 2/3 USSP / Human and Animi Physiology. Tile Action of 'P~,raicftl T Factors. Abs Jour Pef Zhur - Biol.., No 15, 1958, 110. 7o66l Author Inst Not given Title The Influence of Ioniying Radiation on the Lymphatic Tissue of the Snleen and of the Lymph Ncdes Orig Pub : Uspekhi Sovrem. Biol., 1957, Vol 44, No 1, 68-81 Abstract : A reviews The author discusses the influence of the type and dosage of radiation on the degree on injury to the spleen and lymph nodes., and also the histopathologic changes in these organs. Note is 'taken of the role of toxemic factors in the irradiated crganism and the importance of endocrine factors in radiation injury of the spleen and of the lymph nodes. The spleen and lymph nodes are especiaLly sensitive to ionizing radiation. Card 1/1 159 XMTAVZIVOVA. OdnlMrali) dtat,64 Offsails- usp.soyr. btol. Andagento InfGOtIOn IA Sn ir" (MIRA 10:10) 44 no.1:82-92 JI-4 '57- UnICAL MIX?) (RADUTION-PHYSIO C LneHAT IG 5) (SPLUX) .AUTHOR: Konstantinovat M. S. 20-118-4-20/61 TITLE: The Influence of J*-Rays on the Rate of Dye Accumulation in Living Reticular Endothelial Elements (Vliyaniye gamma-luchey na intensivnost' nakopleniya prizhiznennykh krasiteley retikulo-endotelialinymi elementaxi) PERIODICAL: Doklady Akademii Nauk SSSR, 19589 Vol. 116, Nr 4, pp. 698-700 (USSR) ABSTRACT: At the beginning, the author shortly refers to previous papers dealing with the same subject, which, moreover, lead to widely differing results. The author here investigates the time dependence of the modification of the functional state of the reticular eu dathelium in an irradiated organism and its dependence upon the radiation dose. The experiments were conducted with 33 rabbits of both sexes with a weight of from 1,5 to 3,5 kg. 22 of them were jointly subjected to one single irradiation. C06o served as radiation source with a radiation power of 2,9 roentgen Card 1/4 per second. The radiation doses amounted to 800, 400, 100, The Influence of 1--Rayn on the Rate of Dye Accumulation 20-3a8-4-20/61 'in Living Reticular Endotheli&J Elements 50 and 25 r. The rabbits were killed 1,3,7 and 9 days after irradiation. All animals received an intravenous injection Of a 015 percent solution of trypan blue. The 11 animals serving as control received the same amount of dyet they were, however, not irradiated. The lymphatic glands and parts of the spleen were taken for the microscopic investigations. The results of the experiments ~ftre compiled in a table. The data obtained here speak in favor of the existence of a general reaction to a radiation effect. No accumulation of dye is found in the reticular endothelium of the lymphatic glands one daY after an irradiation with 600 roentgen. After from 3 to 7 days the accumulation of dye in test and control animals differs only slightly. 9 days after an irradiation with 800 roentgen the accumulation of trypan blue is considerably increased in comparison to the control animals. The dye was accumulated in the reticular cells and in the endothelium of the sinus (sinus) and vessels. The intensity of dye accumulation increases considerably subject to the Card 2/4 influence of a radiation dose of 100 r. The intensity of the KONSTANTINOVA M.S. Distribution of carboxl and sulfhydryl groups of proteins in the spleen tissue of mice under normal conditions and after irradiation. TSitologiia 3 no.3%293-299 My-Je 161. (MIR& 14:6) 1. Laboratoriya gistofiziologii Instituta evolyutsionnoy fiziologii AN SSSR, Leningrad. (GAMA RAYS-PHYSIOLOGICAL EFFECT) (PROTEINS) (SPLEEN) KONSTANTINOVA, M.S.; NAZINA, T.I.; REYDLER, M.M. Effect of ionizing radiation on the functional state of the reticuloendothelial system. Fiziol.zhur. 47 no.2:226-229 F 161. (MIRA 14:5) 1. From the Sechenov Institute of the Evolutionary Physiology, U.S.S.R. Academy of Sciences, Leningrad. (RETICULOEh-DOTHELIAL SYSTF14) (X RAYS-PHYSIOLOGICAL EFFECT) KONSTANTINOVA, M.S. Role of sympathetic innervation in neurosecretory processes of the hypothalamo-hypophyseal system. 'Bbkl. AN SSSR 140 no.6:1431-1433 0 161. (MIRA 14:11) 1. Institut evolyutsionnoy fiziologii im. I.M.Sechenova Al SSSR. Predstavleno akademikom V.N.Chernigovskim. (NERVOUS SYSTEM, SYMPATHETIC) (PITUITARY BODY) (HYPOTFALAMUS) 0 a TIN-OVA, 14 S. - MI SEYEV 9 le. A. JONSTAN __L Role of the sympathetic nervous system in the neurosecretory processes in amphib#kns. Dokl. AN SSSR 149 no.4:963-965 Ap 163. NiRA'160) 1. Inatitut evolyutsionnoy fiziologii im..I.M.Sechenova AN SSSR. Predstavleno akademikm V.N.Chernigowakim. (NSRVOUS SYSTEM, SYMPATUTIC) (NEUROCHEMISTRY) KREPS, Ye.M., otv. red.; VERZIIBINSKAYA, N.A., red.; VOSKRESENSKAYA, A.K., red.; ZHUKOV, Ye.K.j, red.; ZAGORULIKO, T.Y.,, red.; ITINA, N.A., red.; KARAMYAN, A.I., red.; KkWJ340VA, I.G., red.;.KONSTANTnIOVA, M.S., red.; TITOVA, L.K., red. [E;ibl~ation of the functions; physiological, biochemical and st~ructural foundations of the evolution of the func- tions.-Festschrift for the 80th anniversary of Academician L.A.drbeli] Evoliutsiia funktsii; fiziologicheskie, biokhi- micheskie i strukturnye osnovy evoliutsii funktsii. Sbor- -,u-YIiishchennyi 80--le4.iiu akademika L.A.Orbeli. Mo- nik po skvi, Izd-vo "Nauka," 1964. 290 p. (MIRA 17:6) 1. Akadendya nauk SSSR. Institut evolyutsionnoy fiziologii. 2. Ghlen-korr~ej~ndent AN SSSR (for Kreps). KREPS, Ye.M., otv. red.; VERZHBINSKAYA, N.A., red.; VINNIKOV, Ya.A., red.; VOSKRESENSKAYA, A.K.9 red.; ZfYJKOV, Ye.K., red.; ZAGORULIKO, T.M.0 red.; !TINA, N.A., red.; KARAMYAN, A.I., red.; KARMANOVA, I.G., red.; KONSTANTINOVA, M.S.p red.; PLISETSKAYA, E.M., red. (Functional evolution of the nervous system] Funktsio- nalInaia evoliutsila nervnoi sisten7. Moskva, Nauka, 1965 - 189 P. NIRA 19: 1) 1. Akademiya muk SSSR. Institut evolyutsionnoy fizio- logii i biokhimii. MOISEYEV, Ye.A.;_KONSTANTIMIA, M.S. Effect of protracted action of small X-ray doses on the hypothalamicohypaphyseal system. Probl. endok. I gorm. 11 no.4t68-73 JI-Ag 165. (MIRA 18:11) 1. lAboratoriva gistafiziologli (zav.- kand. biolog. nauk Ye.A. Moiseyer! Dutituta evolyutsionnoy fiziologii i biokhimil imeni Sechen,va (dir.- chlen-korrespondent AN SSSR Ye.M. Kreps) AN SSSR, Lenifigrad. KON,91INTIN1011A, M.S.; MOISEYEV, Ye,A. Change in the basophIls of the anterior lobe of the hypophysis in rats following the extirpation of upper neck sympathetic ganglia. Izv. AN SSSR Ser. biol. 30 no.1:113-118 Ja-F 165. (MIRA 18:2) 1. Sechenov InstItute of Evolutionary Physiology and Biochemistry of Academy of Sciences of the U.S.S.R., Leningrad. KONSTOTINOVA, M.S. Hypothalamohypophyseal neurosecretion following adrenaline and acetylcholine injections In rats. Dokl. AN SSSR 165 no.4t974- 976 D 165. (MIRA 18:12) 1. Institut evolyutsionnoy fiziologii I biokhimii im. I.M.Sechenova AN SSSR. Submitted January 13, 1965. BIRYUKOVA . N. .;' CHMMK.. A. , vrach; GRACMffA,, A. otrakhova delegat; KUIAKOVA, V.., tkachikha,-, _N,_,,_&yaremyy vrach; KIWLEVA , V. PaYmento out of state funds are not "a hirden.4 Okh.truda J sots.strWch, 5 no,1:24-25 ja 162, . (MIRA 15:2) 1. ZamOstitell nachgllniks medsanchasti Gusl4Qwuptallniogo zavoda inani ]Dserzhi6*ogo (for Biryukova). 2. 2-ya Kovrovolca~-,N bolinitea (for Chernyak). 3. Viadindrokay& kontora irri,axi (for Gracheva)- 4. Karabanovoikiy'tekstilinyy kombinat (ior Kulakova). 5. Mookovskiy gorodskoy sovet ~ professionallmykh sayusov (for Konstantinova). 6. Spetsialtnyy korrespondent zhurnaU *Okhrana truda i sotsialinoye strakhwaniye" (for Khmeleva). (Vladimir Provinoe-MWicine, Industrial) KOFSTANTINOVA- N.A. Ecology and relative abundance of carp in the lower course of the Volga River in 1957-1959. Zoo2. 2hur. 40 no.61873-881 Js 161, (MIPA 14,.6) ~ 1. Stalingrad Section of the State Institute of Lake and River Fishery Managemente (Stalingrad Reservoir region-Carp) .44 NIKIFOROVA, K.V.; RENGARTEN) N.V.; KONS OVA N.A. -~~N - Quaternary formations in the southern area of the European part of the U.S.S.R. Biul. Kom. chetv.. per. no.30:3-25 165. (MIRA 19:2) .t~ HENGARTEN., N.V.; KONSTARITINO j A.; NIFIFOROVA, K.V., otv. red.; ~- -VkA, -W PFILVE) A.V.,, akademik, glav-nyy red.; OZITETSOVA, K.T., red.; MENNERP V.V., red.; TIMOFE-YEV, P.P., red. [Role of facies-mineralogical analysis in the reconstruction of the Quaternary climate; as revealed by a study made in southern Moldavia and the southwestern Ukraine.] Roll fat,41allno-mineralogichesko-o analiza v rekon - strakt9ii klimata antropogena. Mosk-.ra, Nauka, 1965. 120 p. (Akademiia nauk SSSR. Geologicheskii institut. Trudy, no.137) (MIRA 18:11) KONSTAINITEJOW, N.A. Find of remains of Archidiskodon gromovi Ganitt et Alexeeva from Lower Levantine (Lower Poratian) sediments in the southwestern part of the U.S.S.R. B-Jul. Kom. chetv. per. no.30:171-175 165. (14IRA 19:2) KONSTANTINOVA, N. A. KOWSTANTINM, N. A. -- "The Dynwdes of the Basic Biological Indexes of Bream in the Northern Portion of the Aral Sea (The Biological Basis for a Rational Utilization of the Atock of Bream).* Moscow Order of Lenin and Order of Labor Red Banner Stat'~ U Imeni M. V. Lomonosov, Soil Biology e Faculty. Moscow, 19~5. (Dissertation for the Degree of Candidate of Biological Sciences.) SO: KnizboAn 11topts', No. 4. Moscow, 1956 XONSTANTINOVA, N.A. Data an Bevan trout stock during 1948-1949. Trudy Sam g1droglol. at&. 14:77-120 055. i WaA q: 8) (Seven, lake--Trout) -MMTARTINOVAt II.A. V"1448i~, i" ncipal biological Indices of bream in the nortbM part of the Aral Sea. Top. ikht. no.10:60-89 '58. (MINA 21:10) I.Vaesoymnyy nauchne-looledovatellakly institut morskogs rybaegs, khosyaystva I okeanogmfit, (Aral SM-Bream) NIKIFOROVA, JC.V.; GRMVA, V.G.; KONSTANTINOVA, N.A. -, , I Stratigrapby of aonti-4ental Cenozoic sediments in central Kazakhstan and their correlation with equivalents in the Urals, TargW Gates, northern Aral Sea region, and the southern part of the West Siberian Plain. Trudy GIN no.26:204-247 160, (Mru 13:12) (Kazakhstan-Geology, Stratigraphic) DOBUNIN, G.K.; KO I Insh., retaonzent-, FILIPPOT, S.D., inzh.. N,, tekhn.red. (Painting machinery for delivery to tropical countries; experience of the Ural Heavy Machinery Plant] Okreska meshin- nogo oborudovantle, post&Tlimwgo v strany a tropicheakim klimtom; is opyta Ural2skogo ~avoda tiezhelogQ mashinostroaniia. Sverdlovsk. TSentr.bluro takha.informstaii. 1959. 38 P. (MMA 14:4) 1. Russia (1917- R.S.F.S.R.) Swardlovskly Abnomichaskly admi- nistrativnyy rayon Sovet narodnogo khozyayitia. (GV8rdlovs;::XIntIng. Industrial) KOICTANTIVOVA, N.A. Significance of the high-water pefi9d.In seaoon'al dymics of biological indices of some fish.opec!,as in the lower course of the Volga River. Trudy sov. J~klt. kom. no.13:420-,~6 161. (MIRA 14:8) 1. Stalingradelcoye-otdeleniye Gosuda'retvennogo nauchno- isoledovatellskogo instituta ozernogo i rechnogo i7bnogo khozyaystva GosNIORHh. (Volga River--Fishes) I- -- KONSTANTINOVAq N.A. - Structure of continental Quaternary deposits in southern Moldavia and nd~acent regions of the southern Ukraine. Dokle- AN SSSR 140 no.1:1-89-192 S-0 '61. (MIM 14:9) 1. Geologicheskiy institut AN SSSR. Predstavleno akademikom D.I. Shcherbakovym. (Moldavia--Geolop:y, Stratigraphic) (Ukraine--Geology, Stratigraphic) KO N.A. Adaptive changes of the biological indices of the floodplain and river fishes of the lover Volga River during the construction of Volgograd Reservoir. Vop. ikht. 2 no.21247-261 162. (NIRA 15:11) 1. Volgogradskoys otdoleniye Goeudarst"nnogo nauchno-issledovatel'skogo instituta ozernogo i rechno o rybnogo, khozyaystva. IVo1ga River-Fishes)