SCIENTIFIC ABSTRACT NUZHDIN, N.I. - NUZHDINA, T.M.

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SCIENTIFIC ABSTRACT
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t7(40b) SOV/20-126-1-51/62 AUTHORSt Nuzhdin, N. I., Corresponding Member AS USSR, Nizhnik, G. 7. 60 TITLE% The Effect of y-Rays of Cc on Early Stages of Embryogeny in Rabbits (Vliyaniye gamma-luchey Cc 60 na ranniye stadii embriogeneza krolikov) PERIODICAL: Doklady Akademii nauk SSSR, 1959, Vol 126, Nr 1, PP 187-190 (USSR) ABSTRACT: Among the poorly examined aspects of the biological effect of ionizing radiation, the effect on the embryogenj of mammals has to be mentioned. Even the latest work dealing with this problem (Refs 10-13) leaves a lot unsaid. In the present article results are given concerning the subject mentioned in the title. One hour before pairing, a female rabbit was treated with rays. The single dose amounted to 850, 300 and 100 r. The dose intensity was 150 r/min. The femaleanimal was then impregnated with sperms of the male animal, not treated with rays. The develop- ing zygote was examined 20, 24, 48, 72, and 96 hours after the female had been paired with a male animal which had undergone a Card 1/3 vasectomy. After opening the abdominal cavity, the zygote was 6o SOV/20-126-1-51/62 The Effect of y-Hays of Co on Early Stages of Embryogeny in Rabbits washed out of the oviduct and of the uterus with a 0.9% NaCl solution. The living macrogametes and zygotes were picked out of the liquid and examined in a hanging drop under the micro- scope. In table I it can be seen that 40 female animals were treated with rays and ovulation occurred in 32 of them. The rest showed no opening of the follicle. All of the 20 female animals used for the purpose of control showed ovulation, there was no exception. 70% of the macrogametes of animals treated with rays were fertilized (control 97%). Due to the results achieved, the authors arrive at the conclusion that ray treat- ment of female animals just before ovulation, does not only reduce the capability of impregnation, but also disturbes the further development of the fertilized macrogamete. This is ex- pressed in the inhibition of the division of the macrogamete and of the development into further stages. Furthermore the macrogamete of the female animal under ray treatment stays 24 hours longer in the oviduct than that of the control animals. The doses of 100 and 300 r also disturbe the normal develop- ment of the zygote (Table 1). On account of all this one may Card 2/3 say that the macrogametes of female animals which underwent ray 60 SOV/20-12b-1-51/62 The Effect of I-Rays of Co on Early Stages of Embryogeny in Rabbits treatment as mentioned above, are highly radio-sensitive. There are I table and 14 references, 3 of which are Soviet. ASSOCIATION: Institut genetiki kkademii nauk SSSR (Institute of Genetics of the Academy of Sciences, USSR) SUBMITTEDs February 25, 1959 Card 3/ 3 NUZHDIN9 N.I.; POMERANTMAI, M.D.; KUZUETSOVA, N-11. Changes in the radiosensitivity of animals resulting frm previous I irradiations. Izv. AN SSSR. Ser.biol. no.6:85i-864 11-D 160. (MIRL 13:11) 1. Institute of Genetics, Academy of Sciences of the U.S.S.R. Moscow. (X RAYS--PHYSIOLOGICAL EFFECT) HUZHDIN N,I.-,--SWIRO,, N.I.; CHUDINOVSKAYA9 G.A,; PANKOVAg N.V. Effect of protective substances on mmalian gonads. Zhur. ob. biol. 4 no.6:430-438 N-D 060. (MIRA 1/.:.I) 1. Inatitut genetiki i Institut biofiziki AN SSSR. (RADIATION PROTECTION) (GENERATIVE WAM) LYSMO. T.D.;_ MUZEMIN.-N.I. For matertalien ia biology. Trudy Inst. ge'a. mo. 27:5-53 160. (KXRA 13:12) (BIOLOGY) SUZEDIN. 9.I.; DOMARVA, O.P. Direct and Indirect effects of ionizing radiation an the mitotic activity of corneal epitheliumo Tru4y last, gen. uo.27:339-347 060. (MIRA 13:12) (Z rays-PtWstological effect) Oraryokinests) HUMEDIS, R.I.; NIZHNIK, G.T. Iffect of gamma *rays of Cd6b an Garly stages of embryageassis in rabbits. Trudy Inst. gen. no. 2?:34$-358 160. (KIRA 13:12) (Gaama rays-Physiological effect) (Rabryoledy-lbamals) 17 (10) s/o2O/6o/13o/o6/05O/O59 AUTHORS: Nuthdin, ff. I., Corresponding BO11/B017 Member-AS-XMSRV Romerantseva, X. D , Kuznetsova, N. N. TITLE: Increase of the Resistance of Animals to the Effect of Ionizing Radiationoas a Result of Previous X-Ray Treatment PERIODICAL: Doklady Akadenii nauk SSSR, 196o, Vol 130, Nr 6, pp 1359 - 1361 (USSR) ABSTRACT: The authors wanted 1) to investigate the type of the change in radiation sensitivity of animals as a result of previous irradia- tionj 2) to determine the dependence of the protective effect on the experimental conditions. For this purpose 2.5-month-old (mainly male) white mice were used. The authors studied a) the dependence of the rotective effect on the dose of the first irradiation, and b the same from the period between the first 5 and the second irradiation. The first radiation was made with 6 doses: 15, 25, 50, 100, 150, 200, 250, and 400 r. The dose of the second irradiation was 600 r. The following served as characteristic values of the radiation damage: I. survival of the mice on the 30th day after the second irradiationj N. Card 1/3 average lifetime of the perished animalal III. change of the Increase of the Resistance of Animals to the Effect S/020 ,/60/130/06/050/059 of Ionizing Radiation as a Result of Previous B011/BO17 X-Ray Treatment body-weightl IV. changes of the characteristic values of the peripheral blood. The following results were obtained: I. A protective effect is achieved by previous irradiatlon with doses of 50-250 r a fortnight before the second irradiation (Table 1). The maximum protective effect was achieved by a deae of 150 r of the first irradiation (Fig 1). Using 800 r in the second irradiation no protective effect could be achieved. A previous irradiation for 4 times with 50 r at intervals of I week pro- duced no protective effect. II. In all cases of an effective protective effect of the first irradiation, the average lifetime of the test animals was somewhat longer than that of the control. III. and IV. No protective effect could be observed. Therefore, the type of protective effect due to previous irradiation dif- fers from the effect produced by chemical protective agents (carbon monoxide, sulfurous compounds, narcotics). In the latter case also a rapid restoration of the body-weight and of the system of blood formation takes place. Among the hypotheses con- cerning the nature of the protective effect of previous irradia- Card 2/3 tion the authors regard two of them as being the most probable: Increase of the Resistance of Animals to the Effect 3/020J61,)/130/06/050/059 of Ionizing Radiation an a Result of Previous BO11/B01"j X-Ray Treatment 1) The protective effect is perhaps connected with the increase of the regeneration processes in the previously irradiated or- ganism. 2) It may also be assumed that the protective effect is caused by the production of antibodies against the products of protein decomposition by the organism. At present, sufficient proofs for this or that hypothesis are lacking. However, they do not exclude each other. They may be only two sides of an adaptation reaction of the organism to ionizing radiation. The increase in the radiation resistance has also been found in plants and bacteria. At present, it is still difficult to find out whether this phenomenon is based on a common rule. There are I figure, 1 table, and 22 reference% 6 of which are Soviet. ASSOCIATION: Institut genetiki Akademii nauk 89SR (Institute 2f Genetics of the Academy of Sciences, USSR) SUBXITTED.- November 26, 1959 Card 3/3 HMHDIN. R.I.; HIZHNIK, G.V. Affect produced by irradiating rabbit spermatozoa with gamma rays on fertilization and early, stages of embryonic development. Dokl. AR SSSR 134 no.6:1457-146o o o6o. (MMA 13:10) 1. Chlon-korrespondent AN SSSR (for Nuzhdin). (Gamma rays-Physiological effect) (Spermatozoa) NUZHDINq N.I.; DOZORTSEVA, R.L. Effect of oxygen on barley seeds irradiated during the period of organic rest. Izv. AN SjSR- Ser. biol. 26 no-5:679-4W S-0 161. WMA 14:9) 1. Institute of Genetics, Academy of Sciences of the v4S.S0R.' Moscow. (PLANTS, EFFECT OF GMVA RAYS ON) (PLANTS, EFFECT OF OXYGEN ON) (SEEDS) NUZHDIN, N.I.; NECHAYLT, I.A. Inherited interlinear differences in the radiosensitivity of mice. Trudy Inst.~gen. no.28:381-401 361. (1411A 14:1-1) (X RAYS-PHYSIOUGICAL EFFECT) NUZHDIN ; NIZHNIK, G.V. _!1ZHD.1 1_j" Effect of gamma irradlation of spermatozoa fertilization and early stages of development in rabbits. Trudy Inst. gen. no.28; 402-409 161 (14111A 1J.-.11) jGA!44A PAYS-PHYSIOLOGICAL EFFECT) (SPERMATOZOA) -4. yuwo AUTiORSg TITLEs 8102 1 1 37/002/018/020 ~B ~~ B103 B215 Nuzhdin, Corresponding Member AS USSR, Pomerantseva, M.D. and Kuznetsova, N.N. Comparison of single and fractional action of fast neutrons on the testes of mice PERIODICALi Doklady Akademii nauk SSSR, v. 1379 no, 2. 19619 438 - 440 TEXT& The authors compare the biological action of single and fractional treatment with fast neutrons on the testes of mice. Data published on this problem differ considerably, Above all, the authors studied the to- tal damage caused by fractional treatment. Changes in weight and in the histological aspects of the testes characterized the degree of damage. Fast neutrons were produced by a 100-kw nuclear reactor, The application of a radiation dose of 100 rad wass a) single and total, b) divided in- to four parts with a total of 25 red each per day. The animals were killed between the 2nd and 70th day after irradiation. Their testes were fixed with Zenker's liquid as modified by Maksimov [Abstracter's notet not explained in the text], colored, and microscopically studied. Histolo.- Card 1/4 ?0744 S/020/61/137/002/018/020 Comparison of single and ... B103/B215 gical sections -~.are made at different moments after irradiation, on the ba- sis of the tyl,,:,3 of germinal epithelium cells found in different stages of gametogenesi~ (method by L.C. Fogg, R.F. Cowing, Cancer Res.9 11, 23~ 19519 Ref. 4), The authors supplemented these methods by classifying the system into three stages. All cells of the germinal epithelium were divided into five groupes spermatogonia, prespermatocytes, spermatocytee, spermatids, and sperms. Table 1 shows the effect of dividing the 100-rad dose into four fractional doses on the change in the weight of the testi.s. Hence the authors conclude that the latter is considerably reduced by single and fractional irradiation, i.e., mainly on the 35th day after irradiation. Fast neutrons are 5-6 times as effective as X-rays. The degree of weight reduction is constant regardless whether the 100-rad dose os applied to- tally or in four portions of 25 red each. On the 70th day after irradia- tion the weight of the testes had not been restored. The intensity of re- generation was equal in both experimental groups. As to the spleen, the case was different since its lose in weight wan lower with fractional ra.- diation doses (Table 1) and X-rays. Germ cells, starting with the youngest (opermatogonia), gradually disappear under the action of fast neutrons. At a dose of 100 r, spermatic ducts were found to be not completely empty, Card 2/4 Comparison of single and ... S/020/61/137/002/018/020 B103/B215 as destroyed mature cells were replaced by younger ones. Also in this case, the biological effects of single and fractional doses were practi- cally equal. The authors state that the action of fast neutrons is not re- duoed by fractional doses. They thank B.M. Isayev, Yu.I. Bregadze and V.A. Kvasov for valuable advice. There are 2 figures, 1 table and 5 re- ferences: 3 Soviet-bloc and 2 non-Soviet-bloo. The reference to the Eng- lish language publication reads as follows: G.J. Neary, R.J.'Munson, R.H. Mole, Chronic Radiation Hazards, London, Paris, N.Y., Los Angeles, 1957. ASSOCIATION: Institut genetiki netics, Academy of SUBMITTED: December 10, 1960 see %a e0c'r ;;~ 0 ;WX Cam "Kaxit 0,;;- to Card 3/4 123 0.V to CeA eNKA . 1 1 kkademii nauk SSSR (Institute of Ge- Sciences USSR) 2 7 A- sec 41(c. j-aec AO ^K- T- oo 100 rad 17" W 0 54 0'6'1 7 25 r&dX4 151 0:52 1 13' [ 70026 100 ad - ' 93 0.32 8 25 sdx4 53 6 S 11 1 0,40 6 73 0. 31 7 S.- Phylt.1-0cal --4 1111-1-isiltal Pecallsliles of Mice .11h Diftering Inborst Radlosensill,ify 0. %f. Graye"Ismys, N. 1. NvLMbR, 1. A. Nectuir" 04 R. N. Scfw4fl" M------- A Inveslilplions on the radiosmitivity of different strains of animals do not, as a rule, involve the analysis of physiological, metabolic of anatomic peculiarities defining the giwn straint. in contraut, studiti of physiological and biochemical differences between strains am generally carried out without relation to radisiscr,0111vity. A comparison was ninds: of the body "vight and bight of liwr. spl"n. Auptaienal glandi. thymus and iciticks, and or the level of adrenal and carbohydrate metabolism, belween [bite strains in a normal state (CIALII/c, CjI( and CC.,Dr) and one population (Mbirso) of mice characlersicil by differing radjuscissillvity as dcflned by she ILD 50130 close. It has been the" that ndior,tsistant ttr,int of mice (CC-Hr and albino population), as compared with radio. sensitive orses (RALYI/c and C.11) have greater %vichit of liver. spWri and thymus, a higher content of catecholAmitt" In the4ups-arcruil glands, and a reduced glycoges, k~l In the 11vtr tissuc. T1w lattte phe-~ sprevim to b. of . c..4acy -d- and derndt to a consisIciatble ast"t on the Inteftity of the estirch%lamInst metabolism In the upraressid glands. USSR At- roport PmentaA at the 2rA Intl. C*aveae of RaUatUn Reglearah, ZMMAftt*/1Ork3h1M. Gt. Brit. 5-21 Aug 1962 S/872/62/000/000/001/006 ;X C B144/B'60 AUTHORS: Nuzhdin, N. I., Dozortseva, R. L. TITLE: Cytologic analysis of barley seeds gamma-irradiated in the state of organic rest (Peculiarities in the formation of chromosome aberrations, oxygen effect) SOURCE: Deystviye ioniziruyushchikh izlucheniy na organizm, Inst. genetiki AN SSSR. Ed. by'N.I. Nuzhdin. Moscow, Izd-vo AN SSSR, 1962, 5-30 TEXT: After a comprehensive review of Soviet and Western sources, the present experiments are described. Three types of barley seed with different organic rest periods and radiosensitivity i.e., Moscow winter (A), Odessa-17 (B) and Yugoslav winter (C), were CoIO irradiated.-nith 12 cu. The frequency of radiation-induced formation of chromosome bridges in the cells of the rootlets was investigated for each barley sort in 3 groups of seeds after passing out of the state of organic rest either: 1) spontaneously; 2) artificially after removal of the seed coat and puncture near the seed bud, with immediate germination; 3) as 2), V/ L"\ Card 1/2 S/87 61/000/mc/1001/0006 Cytologic analysis of barley seeds ... B144YB150 but rith germination after 10 or 20 days. In all ~ barleya the all romoLjorriu nborl. ,It Ion a liol-41 " 1 00~,,, hiplior in .~rouypfj 1 rintl )' than In 2. To resolve the controversies on the cause of orLanic rest, which many authors attribute to anoxia, the effect of N 29 021 air and vacuum on the number of chromoijoine aberrntions wan .9tudied in it further nerien of tents where A and B were irradiated in orpnic and induced rent. 'Pho pu'nultu are represented by the order 10 = JA = JIJO = -IIA )IN = IV = JID = IIA 2 -,7% N V N V M I I T I I T -.,,-nere I are seeds irradiated .1r, organic e/ ~ in ina'Luc' est after this; 11 are rest and ~~ p ed r seeds treated as in !, but germinated immediately after leaving the state of rest; III are seeds irradiated in induced rest; 11 = nitrogen; 0 = oxygen; A = air; and V = vacuum. Two previous assumptions are con- firmed: The state of or.-anic rest is the result of anoxia caused by the impermeability of the seed coat to oxygen. Irradiation produces real and eo potential breaks of.chromosomes; und r the effect of 02 the potential breaks develop to real breaks (the aberration percentage increases), and in the complete absence of 0 2 they disappear. There are 4 figures and 12 tables. ,aru' 2/2 112631 S/747/62/000/000/002/025 D268/D307 Aumoas: Nuzhdin, X. I., Jhapiro N. I. and Nechayev, I. A. TITLE: Comparative characteristics of radiosensitivity in diffe- rent lines of mice in relation to,genetics. The role of hereditary charac-Leristics in animal radiosensitivity 60,6RCE: Radiaisionnaya genetika; sbornik rabot. Otd. biol. nauk All SSSR. Moscow, Izd-vo AN SSSRt 1962, 24-38 T.T,'XT: Radiosensitivi-,,y was studied in ca. 2 1/2 month-old male and female mice in 4 lines and 1 subline, irradiated with single x-ray doses at 350, 425, 500, 575 and '050 r. Interlinear differences in radiosensitivity were ooserved. Por males TuD 50/30 fluctuated in the V~ range 538 - 413 r and for fena-les in the range of 559-465 r. A close similarity in irradiation reaction in intralinear males and females was indicated by the hi6h dOsitive correlation coefficient for LD 50 values for males and femaies of a single line determined in inter- linear mortality comparisons. The data showed that females were - -' /2 6/747/62/000/000/002/025 Comparatice charact,_:r-~._-.ics 3f ... D268/D307 8omewhat more resiSta:.t :..aies. ~,J 50/30 for males of line 33 NA was 12.8~o above that fj.- ana 3 - 4% for the other lines. Ave-a-re life duration uo --Le dose increased. Interlinear difier'~ences in life r e mu re pronounced at 350 and 425 r, even4n~ out somewha,. ie-.Iiai effects were approached. in contrast to males, fQ.-.aleB sh3.:ed little interlinear differences in life duration. of !-;fe duration in males and females in 3 lines showed 4t -z. be ~o-e-a'-,a-~ :,~~her in the former than in the lat-~er at 350 and z~zD r. 1-. was good in females at 575 and 650 r. The p.h,ysioLogical of radiation death in animals of lines differing in ra";_4ojensi-.iv_,ty seemed to be uniform. There are 7 figures and 6 lables. A 6 6 OC IAT 1014 lnstl-,u-z. L;enotik-.'~ 366R ( Ins titute of Genetics AS j66R) blologichesk.)y fiziki AN SSSR I Mos- kva (Inot_"~L~te of ~3iological Flrjsics AS USSR, Moscow) Card 212 6,~ 9 oC j2- OL t3 se -q p- -01 5). - 0 -IL ea3 J - ji Z3 ji 61, j/k.)2~ e Of ),~ vu e s 3 f n c LL CA V I V on n s fo-, c I -z--.e -~~z3e 3-, r -c zi U 1. .'cv,2r, -r-~.c ona on UIVI 0 -47fc~c ts 0 f .,.,a t:- or, Pr e -r. - -V e zjc..'~tes z, uf f c: ian Le- -- e ~~ry i c ao e f 1 2 e j nu -.1' f n e i c a T, 11 T 1 0 1 e S,CD -~J I."- ul t,~-.e cff olog4 cal Phys'-I'S AS Jlj")i R, 42690 j/747/62/000/000/011/025 D2 96/D'307 Jhapiro, N. I., Petrova, 0. N. and Ki- tuyeva' 0. N. influence of x and Cradiation.upon the oestrus of mi c e -OU2,OL: Radiatsionnaya genetika; sbornik rabot. Otd. biol. nauk hoocow, Izd-vo Ali 6j"JR9 19629 133-179 Histologrica" and crous-breeding methods as well as observa- -t--on of -uio oe6trus nave been extensively-used to study the mecha- -sin resjonsible for radiazion-produced sterility. The authors cri- -.1--ize -cl,c technical shortcomings of previous studies which led to contradictory results. TheyL;tudied the effect of ionizing radiAtion .-,~.)n tlie fertiiity of female mice, by following up the oestrus as- ~n- un.,3tained vaginal umeL~rs, taken daily in the first three months, t ~ Z -L."d uijo in the sixth minth after exposure to total body radiation. ;~'a pl'-.uses of the cycle were established qualitatively and quanti- -1 -'.~-uively on the basis of the relative droportion of the 3 main ele- rd 1/3 6/747/62/'000/000/011/025 .Zhe influunce of x ... j2 961/ i) -~ u7 e,~i-une`al cc-- es. t~s the -L _L ~j' fluices and leucoc," a saLijfactlory bu-C neverTioless indirect index uirj nui,iu(_,r )ru,;-,ancies and of progeny %%,as also re- JL1-'_iC:1L'.1Qr1 I.If6cr the irradiated femaler, had been -~Pt .11iti, I'J k~ 1JI. in-le exoosire to x rays was found -u,) -.~ucfeaL;e 'u:.a namL)-_-r o.- I c,,,rc-es and their frequency in the group --ithir, -.no clo-'e the )roportion of the pro-oestrus and oes- zrus z3zae were dimin_*,3hed and t`ie proportion of -,i-ie met-oestrus Ji-j; L3zruo sra,,re c;J.1're6,)ondin--1y increased. e decree of t.-lese -iroctiy uz:pon,lent on the dooe and on the time since -_e .,xpoj,,tre. jose8 ur-or 5J r had no effect upon the oestrus ai- -_urlulllty was imp:Lired even Oy doses of 15 - 25 r. After ex- 1.0 1)0 f a "!atency .juriod" of 6 weeics durin;, which r`ii_oc-u _~l 1,10ticed .~;.d ~.-.,i,ich becomes shorter after (_.xposure to ~\JO - 4VO rj. ~ MOnthli llft0l~ thO ifl',Adiation no cycleB .~e o jLe.,vA in ~L,-," of the animals. The disorders Were irre- a-~ --east fD2 pcriod if observation (6 months). Nulli- _u1'u_;,,..r,ju,3 as -,,-ell as mice of different strains 1*~j6,1j...~!Ca in a 61Mi -_'Lil' -_L1i.,cr. Ikironic exposure to r rays, even in C"-;-rd z/3 3/74 62/000/JOO/011/025 e e n c e u f x ... YD307 D296 ~~;;,aii do,t~.;, very clo-jo to the maximum purmissible J fter a latericy period of 12 months zotal uoje 118.7 r) up to 15 months (0.2 r daily or u.! r Uaiiy - total doue 36.4 r). O.J5 r,daily -a oes,.rus. There are 15 figures and 12 tables. dose, led to si- (0-4 r daily - - total dose 72.8 r had no effect upon "'juC LLTiON: Ins%J tut genetiki Ui L;,jJR (Institute of G enetics, Ab U-0ja) ana Institut biologicheskoy fiziki AN i3z3~~,R, i."osicva (Inz.,ti-vu-te of ijiological Physics, AS USSR, "108cow) r'ard 3,'5 L. 14 91c) S/87 62/000/000/005/006 B144YB186 AUTHORS: Nuzhdin, ff. I., Nechayev, I. A. TITLE- Effect of radiation blockers on survival and changes in the internal organs of x-ray irradiated mice of different radio- sensitivity (Diethyl stilbestrol effect) SOURCE: Deystviye ioniziruyushchikh izlucheniy na organizm. Inst. genetiki AN SSSR. Ed. by N.J. Nuzhdin. Moscow, Izd-vo AN SSSR, 1962, 173 - 197 TEXT: Three inbred strains of mice, CC 57-brown (1), C 3H (II) and BALB/c (III), wero subjected to a single whole-body irradiation of 600 r in order to study the effect of one prophylactic sc injection of 0.2 mg d.iethyl stilbestrol. propionate (D) administered 10 days before irradiation. The LD 50/30 for these mice were 538, 490 and 442 r, respectively. Administra- tion of D reduced the total mortalit b 50 ~ in I and II and by 66.7 % 9~ y in III, the first peak (UP to 5 day being significantly reduced and the second peak (10-12 days) disappearing almost completely. The weights of Card 115 S/87 62/000/000/005/006 Effect of radiation blockers on ... B144YB166 thymus, liver, spleen, suprarenal glands and testes were determined,2, 4, 7, 14, 21, 30 and 60 days after irradiwt-ion. Groups II and III differed originally only in the weight of the tectes, but group I had distinctly higher liver and spleen weights than the two others. In non-irradiated mice, D administration did not affect the total bodyieight. The.radia:- tion-induced weight variations of the thymus were similar in the 3 groups and not affected by D. The highest weight of liver with the least fluc- tuatione was found in the moot radioresistant strain 1. The effect of D on this organ became-evident 2 weeks after the irradiation. The weight curves of the spleen whose radiosensitivity is reflected in the second peak of the mortality curve (failure of the hematopoietic system) showed the highest absolute values and an earlier period of overcompensation in group I. D accelerated regeneration, inhibited overcompensation and equalized the otherwise differing spleen reactions of the 3 strains. The--- weight increases of the suprarenal glands produced by separate and com- bined irradiation.and D administration were similar in the 3 groups. The difference in natural radiosensitivity was not reflected in the weight curves of the testes chose regeneration was not improved by D. The diver- gent radioresistance of the 3 strains is attributed to the different radioresistance of their spleen and liver, which is evident from the Card 2/3 S/87 62/000/000/005/006 Effect of radiation blockers on ... B144YBI86 weight curves as well as the diethyl stilbestrol effect. There are 10 figures and 20 tables. VAk Card 3/3 h2691 S/747/62/000/000/012/025 D296/i)307 J, 1. , ~'iuzhdin 14. 1. and Kitayeva, 0. N. 'I'," 'tudy of cau seG leading co disorders of the oestrus .r, mice expoued to total body rad.iation C; Radiatsi onnaya g enetika; sbornik rabor. Otd. biol. nauk. AN SiijR. "lobcow, I_zd-vo 4...N L;JJR, 1962, 180-210 1-1,2: In a previous japer 'Jb. rabot po radiobiologii, Izd-vo AN 1 15-14,j) t.'.o _iuthorB had *hown that the oestrual cycle mic ei~s i.i~-hiy rLdio"Qnsitive. In the present study the authors tr.ed to eoTabiis1i w),eti,er the sterility qaused by ionizing radia- -,j ~ae a) to Jm,airr-,,~nt of prALICtion of the gonadotroijhic o, 10 r,.-, '_-1 11 efrom, the pitai-.a.ry gland, b) interference with the res'ponse t~ t-e vainai epltl.clium to oe6tri-ena, c) destruction of the ova- Y " , U i 1~ ;an 101."~cies, or a) ozi.ur cau.,;es. '.-'.ey also tried to devise an sechnic-lue fir the restcration of the oestrUS. Mice were expo6ed to total bouy ii-radiation by means of x rays in a dose of 1J6 r; homo,;enales of ifie pituitary 61ands were then used to carry Card 1/3 ~V'747/6 2/000100010 1 2/25 ,;tudy of the c"--6e6 ... D2 jb/D307 0-1, ~-t zoncle'c veaction on infanTile mice and were -,o possej6 t..o nor~,j- -onadotr,),p1iic activity. The va,~inai of 'Llie 6ave a normal response to injec- Oes-~rDl-, as shown by vaginal smears. '2'.D tli'ir t.,.-,1U .,.'wer-exp,)sure to rudiation of the follicLos ~UU6e ~)` the oejtr~lai aisorders, tne transl)iunLca nj-,-,7,,L' vuries Jn-.o the irr~tdiated :,,,ice, w Iriere- .,,o normal oe~,-.rab c-lcie laao restored. If t.%e transplanted lv~'Lrio-3 ."ere Ve;aoveu or under,.ent rL,~-)r,,tion the cycle 3ecame a1z;ru,-ved. ,oio:,Jcal inveotigat~on revealed com- -o~,ence of fo~-iicjes ana art almost comple-.e lack of corpora i.utea in Ll'e ovaries of u;,c ifradiated mice. These ovaries mainly c,,n~,-iszcd of strom" -.1'e transplanted ovaries showed a nor- L;L.---tare. '2o Whether very high doses of gonadotro- cau~u L,~)duce a response from any residual ova- C! -r, -'-~raa'ated ovaries the mice were riven 60 mouse ts of 1:-oruao-uro,)ki-Lc '.'..~rmorie. The ovaries and uterus responded increase in -,lci_;ht. bind size but no restoration of the atro- couii je obu-rved. There are 13 fiures and 6 Ca-~'Seo 8/747/62/000/0 tut D2961-0307 00/c) ,Iiv I Ogi Cl 121()25 rls t i ~Cva ( 8;~?y fizik, tu e lrl~ t.1 t Ut t Of Genetics 9 Ase it t USO&D'Ologicalu genF-'tlkj 1106COW) Physics and 42692 ~i/'14Y0 2/000/000/01-3/J25 U2,j6 1)307 6, 6hap4ro, N. I., Suzhdin, X. I. and Petrova, 0. N. influence of x rays upon the survival rate and fer- zility of guinea pigs -Uu.,.'Cl~: ;-tadiatsionnaya Genetijca; obornik rabot. Otd. biol. nauk AN J3~;R. Noscow, Izd-vo jiN '6*0"Oll, 19062, 211-235 T Ab a contribution to Lhe COL]parative radiobiolo[;y of -xi.-Mals ztadicd the le~.I,al effects of x r, -ays u,)on guine;i pigs LIL -exes ~nd L~,~ ~jLcrility caused by icradiation in fe,,iale jj~-s. 250 uni,-.ials were expoL;ed to total body radiation with .K [-L4y2 irl do~,es rangirVfrom 100 to 2150.0 r at a rate of 42 - 56 i-/niri. ;Lialcu )roved To ue much nore radio~;cnsitive: the k.,ouc for mulou .-as 500 r comi):,-red to IJOO r for fera-cs. -es .-,.c cc;~j,)ective values for Lji 5o/30 ware 235 zLnd 365 r. The mz4j. ,)L,ri~;hcd more rapidly and lost more vrci6ht. 'This marked sexual bi- haa not been previously dci~cribed for any othor mammalian Curd 1/3 ~j/'! 000/ J,),)/'O 1 `5 025 ay 6 ... ~..,c -iflucrce of x r, J 2 -j o /if~ 07 L To :jzucly the sLerii-ity zoL~Li b,)d 'y i -Lve b t, tea the r,~,l u %~ncy .~.-, ~-Ors ii d r;urat ion o f t'-.c on,,:, in fe:::Ula~; UzAa, 00;61: Of irwic.%tor: r.- G e 0 2~,c,. u,21'ec-~ ol' irrad-.-.-- C 0 (IUZLI.~-- J i, 111 'i r~IZ lrQ 0 -L',- V - i_' 0 co IF. ' Oil- -.'Orl, IT T, -aL :-ao of tlc -row- d3L,~; C! -act il~:~ rad-.- uxe) (iff-C 1-0 U~)Jrl t, r t 1"0 C ~:L- c i -~y D a,~ --* t ho um- t o ,.c 6 c .k"C' (101~- Of tLiO Wa~-ICS f o II c e ~i c u un -. e d .i L3 ..: a s n c, a ~: r 3 t'iu hc;.-.ca Tj;e i:, no --d-ex of sterility jy izraci:.,~Oa. -.ccordi--n,,,- -ci the.-ir own invest irration~; C---.cci 2/3 5/747/62/000/000/013/025 influence of x rays ... D296/D3J7 d' -tta in '.fie literatixe, 4 mammalian species can be arranged in the fj.Liowing (decreasing) order with regard to their radiosensitivity: C. mju~,e / man -ra' >guinea ,ig. There are 6 figures and 5 tables. -'iT i 6 N1nL;titui biolo~;icheskoy fiziki i Institut genetiki kN 66oR, L-Ioakva (institute of Biological Physics and Institute of Genetics, AS USSR, Moscow) Card 3/3 NUzwkN' N.I.; DOZORTSEVA, R.L. Characteristics of the formation of abrowsoma aberrations in irradiation of seeds in the state of organic rest. Zhur. ob. biol. 23 no.l-.12-23 JaF 162. (MM 15:3) 1. Institute of Genetics, U.S.S.R. Academy of Sciences. (Caomasass) (PIAMS, ZMCT OF GAM RAYS 09) (SE9W) G10SHCHENNO, N.I.; NUZHDIN, U.I. Biological scionces toward the fulfillment of taakn set in tba-program of the GFSU. Zhur. ob.biol 23 no.3:161-175 My",10 162,, (141RA 15:6) (BIOLOGICAL RMEARCH) S/020/62/143/003/028/029 B144/B101 AUTHORSt Nuzhdin, N. I.v Corresponding Member AS USSR, Kuznetsova, N. N., and Ramayya, L. K. TITLEt Effect of x-ray irradiation of pregnant animals on variations in the peripheral blood of their progeny PERIODICAL: Akademiya nauk SSSR. Doklady, v. 143, no. 3, 1362, 717-720 TEXT; The postnatal effect of a single intrauterine x-ray irradiation of 200 r at different embryonal periods was studied in mice by complete blood counts. (1) Hemoglobin quantity in newborn mice was most reduced after irradiation on the 17th day of intrauterine life (i. U. 1.) '. P.- (H - 8.6), but was soon restored to normal values; in 45-day old mice, irr%diation on the 13th day of i. u. 1. produced a significant reduction R - 7-0) in spite of almost normal values at their birth. 2~ Erythrocyte numbers varied consistently with the hemoglobin quantity. ~3 Reticulocyte numbers were temporarily reduced in newborn animals ir the 13th - 19th day of i. u. 1. (R - 3.7 - 5-3). (4) The white blood count of newborn animals revealed no aignificant Card 1/2 S/020/62/143/003/028/029 Effect of x-ray irradiation of ... B144/B101 variations. Myelopoiesis was not inhibited. In 45-day old mice leucocyte numbers, neutrophils as well as lymphocytes, were significantly reduced after irradiation on the 12th day of i. u. 1. (R - 3-1); whereas irradiation 1 day later affected only the number of neutrophils and reduction approximated significance (R - 2.5). Thus, the maximum effect on the red blood of newborn mice was detected after irradiation on the 17th day of i. u. l.; this is probably the most important period for bone marrow formation. Development of leucopenia and anemia in 45-day old mice irradiated on the 12th and 13th day of i. u. 1. may be due to destruction of mesenchyme rudiments of blood-forming tissues. There are 4 tables and 7 Soviet references. ASSOCIATIONt Institut genetiki Akademii nauk SSSR (Institute of Genetics of the Academy of Sciences USSR) SUBMITTEDt December 11, 1961 Card 2/2 I -NUZRDIN, N.I.; MECHAYEV, I.A.; GRAYEVSKAYA, B.M.; SHCHEDRINA, R.N. Some phyaiological and biochemical characteristics of mice vith different natural radiosensitivity. Dokl. All SSSR 143 no.4097-1000 Ap 162. (MIRA 15:3) 1. Chlen-korrespondent AN SSSR (for Muzhdin). (X RAYS--PHYSIOLOGICAL EFFECT) (ADRENOCORTICAL HORMNES) (LIVER-GLYCOGENIC FUNCTION) -NUZHDIN, N.I..; KUNETSOVA#U.N. Effect of I rays at different periods of embryonic development on the testicles of pubescent mice. Dokl.AN &SSR 145 no.6:1393- 1395 Ag 162. (,,g-T?A 15:8) 1. Iwtitixt genetiki AN SSSR. 2. Chlen-korrespondent All SSSR (for Nazbdin). (I RAYS--PHYSIOLOGICAL EFFECT) (TESTICLE) NUZHDIN, N. I., DOZORTSEVA, R. L., and SAMOKHVALOVA, N. S., "Dependence of the Effect of Dose Rate on the Physiological State of Irradiated Objects. " report subndtted for the llth Intl. Congress of Genetics, The Hague, Netherlands, 2-10 Sep 63 NUZHDIN) N. I., and NIZHNIK, G. V., "The Effects of Protection Against Genetic Damage caused by Ionizing Radiation in Mammalian Sex Cells." report submitted for the 11th Intl. Congress of Gerietics, The Hague, Netberlands, 2-10 Sep 63. L 19o66-63 EWr(1)/E~T(m)ADS/F0(.J)_. AFFTC/AM/ASD AH/K ACCESSION NR: 5/021.6/63/000/004/0514/0525 AP3004278 AVMOR: Huzhdin, N. I.; Dozortseva, R. L.; Samokhvalova. H. S. TITLE: Dependence or chromosome aberration frequency on irradiation intensity and physiological condition or barley seeds SOURCE: AN SSSR. Izv. Ser. biologichaskayat no. 4. 1963t 514-525 TOPIC TAGS: barley, seed, chromosome,, aberration,, irradiation intensity# gamma irradiation# natural dormancy# forced dormancy ABSTRACT: Two types or barley seeds, Odessa 17 and Hibernating Moscows were gamma-irradiated to study the effects of high and low radiation intensities on seeds in states or forced dormancy and natural dormancy@ Odessa 17 and Hibernating Moscow were gem=- irradiated in both states with doses of 12 kr and 15 kr respectively at different intensities (Odessa 17, 423 r/mIn and 55 r/min; Hiber- nating Moscow, 301 r/min and 43 rfidn). The frequency of calls with chromosome aberrations (dicentric bridge and acentric fragments) in the meristems of the root tips was investigated during mitotic divisions. For seeds irradiated during the forced dormant state the effect of the radiation dose rate Is sharply axpressed regardless Of, Card 1/2 L 19066-63 ACCESSION NP.: AP3004278 germination time. The high radiation dose rates produce much.highor percentages of chromosome aberrations in the root cells than the low crates. For seeds brought out of natural dormancy artificially and .germinating 1-1=ediately, the percentage of root cells with aberrations is the same for both the high and low radiation dose rates. The same .seeds brought out of natural dormancy artificially and germinating 10 days later show dirrarencos in radiation intensities identical to the ;seeds irradiated in a state of forced dormancy. The frequency of ,chromosome aberrations in root calls depends on the physical conditiors of irradiation (type of radiation, dose, rate) and the physiological state of the -eeds during irradiation. Orig. art. has: 2 tables. ASSOCIATION: natitut genotiki akademii nauk SSSR (Institute of Genetics, Academy of Sciences sSSR) SUBMITTED: OBApr63 SUB CODE- AT-1 Card 2/2 DATE ACQ: 15Aug63 110 REF SOV: 004 ENCL: 00 OTHER: .034 NUZHDIII,_ I.; SHAIIGIN~-BEREZOVSKIY, G.N.; PASTUSHERKO-STRELETS, N.A. Change in the radiosensitivity of' barlev under changing life conditions. Trudy Inst. gen. no.31.55-79 164. (141RA 17:9) 1111ZHDIN, N,',; R,T.; "AlMOKKALOVA, N.'. Foo%radiation effect of otcruge In barley scirj6, irrar,!&Iod -.1, th gamma rays (C,,~O) , in the ctpt,-3 of L,rgan!,i ar,(j forced dormanry. Izv. AN SSSR. Ser, biol. no.~,577-586 JI-Ag ltl,. ( MJ RA 17 , ---0 ) 1. institute of Genntlcq, AcudjriCt of Sclen~!et; ~f tnp F.~ S.R,v Moscow. NUMINT, II.I.; Kl]ZNFTSOVA, N.N. Radi-~sensitivit7 of the lymphocytes of the peripheral blood in vitro in animals belonging to variaus genotypes. Dokl. AN SI,3R 159 no.4z923-925 D 264 (KIRA 18-.'L) 1. Institut genetiki AN SSSR. 2. Chlen-korrespondent AN SSSR (for Nuzhdin). W L 63 EEO tj)/tss, FS (7 -2/3 dG (r ~/EMI 555-~65 EW6 !(I)/ - (a e_1 7~~ E~MjMl La I w. 2 P0-1,ZFe-5L~g=h_/Pa~.=h&a A 3ESSION nR:- AP5017766- CC Ug/0216/65/000/004/05T6/0580 -581. #16T:629.195.2 ATMOR:-. Nuzhdin Pastushenko-Strelets, N. A. SamokhviObva N. 5- TITILS: The- -Vfect:,of space-flight factors on seeds -of the spindle tree (Evonymus europaea). SoURCE. kvssml,~ lzvestiya. Seriya bidlog cheskWa,:no.~ 4, 1965, 576-58o TOPIC YAGS: manned space flight, Von t 6k _5 plant seed, ge-mination, space flight, 0,ological ef fe.ct weightlessness, gamma ra'diation, plant genetics, mitosis Ax~ . ~im i i I! r OR-8- imul A7, we -rrin f ~( _% - v - 7 1-6f I ~ ed cn, gh7t_jdi!t- A eeds opean r ion -an 6 f f hii 71. e s, upind!6::-t~ee-, U, Von imp fo -8 months &nd then ymi).s.europaebL)--.~ierekept-.at---rooti-ti eratute r irradiated with C660 gamtaa rayff (do'se, 10 krad; Inten5ity'i i'27T-,rad/min). Irradiated G-nd unirmdinted seeds were sent on the Vmitok-5 flight. One control 13roup of li- radiated and tmirradiated. seeds was flovn to the cosnodrome~ mid another was kupt in IMoscov. Spindle tree jjee6s were chosen' for this stutly because they have a I.ong ,germination period (12-18 months) and becatise they rxre in a state of forced dormancy, 77 L 63555-~5 ACCESSION-R-I'LL -AP5-017%7766- ie~ ~-that - ce -flight.:-_fact is do); 0 as oppose o orga-hie'.dormancy; X had, beerv suggest, ~d spa not sti"mulate germination, but only cause the trans4-tion of seeds from the ritate Of i orgKnic_domancy. After the flight, it was necessaxy to stimulate germination of the seeds which obscured the study of the space-flight effect. After germinat ion,,.,,,. J, rootlets vere~fixed and the number of cells with chromosome aberrations was _:j counted. Cytological analysis of the first series of experiments (seeds not pre- .viously irradiated) showed a reliable difference between experimental seeds and both controls. However, with previously irradiated seeds, statistically reliable differences were observed only between experimental samples and the Moscow control., The increased frequency of abnormal.cell divisions in experimental material is proot -that__spac~_-~ightfactors cause -chromosome. injuri6s in tells of spindle tree seeds. 1 pr6i*_ WT-. iadat - -o-f -A de-c Fs an & t he - :a ub a e qu ant in t-wa&~_c one udeVtl id gamma. _.fir flue a-s ..e ec on~t e:_formati nce-. 6 sp --6t -ten f ace--fliiht-lAdtors upp emen on with abnomdl~iitos6a'.' :The increased nxuaber of chtomosome aberrations among s8Mpl60--_--' flown to the cosmoaromd, Uhich was approximately the same In both series of experi- Iments, is unexplained.and requires further study. Orig. ai-t. has: 1 table. ASSOcIATION.t. -, Institut genetiki AN SSSR (Institutj~ of Genetics, AN SSSR) suwamm iWan65 ENCL! 00 SUB CODE: IS NO REF BPV*. Ole -OTHER,. 001: ATD pREss: 4050 Card 2 Z'We~ ~ tutluence at &nnLbLtors:&nd,~&ctLvatorv of cellular metabolLd on the numfier.otchr6mosome aberrations after s Lngle.- dose and fractjon~ - a-t- d., a re e .g mma. ir 4istion ot barley seeds ~SOURCEs ~~,AN SSSRO-Anstit'Ut -gens tikie' Trudy.,no, 32 VeystvLye: 1965.: iotiiztt'uy~ushcULkh',:'Lxlucho'nL*. na~: rat t te V nyy i zf&ir*tnyy organi zmy L --(Effect ~of:'LonL zing ~'rsftatLoa ow pt 4t and organismis) 4-17 TOPIC TAGS,u. plant: genetics, radiation plant effect, barley. gamma irre- diatlan, an tib io ti c, a trap tomycla, levomyce tin ATP AB STRACT,., 'Ur-drLed see,ds:of two 4arietL4s:-of Winter barley, odeaskiy 17': 'And ZinuyushchLy we re: j Irr&diated,w*jth:Co6O gamma rays in 's d1ofie: of k1rad -wi th dos3. power of -.361 rad/mLas Seeds were irradi- _St6d' by ~ two methods. An.: one,: dos e and in two'.-dooes, of - 7. 5 krad -each sep- ,ara.ted bj-.,,&n. Latervall, of :15. days, Twen.Ity-1our.hr after the first Lrra- A181iozkbi the,1ractLonated-methods and 24-hr:'after,single irradiation, sea do vice 'so' eked lor: 24 hr -to solutionsof levosycatin, streptomyeLn, a rd ;ACC.NRt n5o24242 SOURCE COM. UR[26TO16510001032/ooie/oo6o e R -Fastushenko4trelets M. Al-' AIMOR Nuzhd1n (Corresponding memb r AN SSS Shangin41erezovskiy,--G. N. m:ssu (iustLtut:genttiki WWRY .. ... .... ORG:-..jjjjjtute!6f -Cosuatics ,L d _~h. TITLE. ~:Thii -effect 6 ecological cativation',condLtiong an lhi-, *s1ol'agical II- ti of A." d i on eeds:, degree of maturity) on radloseinsitivity,and the frequency and ch .-acter'of hereditarjr,. changes. in, gamma-irradiated. barley. SR. etiki e ionizirti" - SOURM: S-6 Trudy~ no. 32, 1965 Deystviy 64161dift-laws idi nit.' -i,,zhivdtnyy organi=q (Effect of lonizing radiation Tastitel nyy: and a6iiid or ganiew TOM C T.AG.S,-. Plant'. genetics biblo ic miitition,~hereait it -ology,:radia- X, p ant physt -effectj plint ecology ne -:Of fferen did AWTRAM-,` Experiments were co6diated td,determl the effect dl t ecdlogl c6nditi6n~ -the on, sensitivity to::irradiation.of garnma-irradiated barley seeds, The: aose' of ga=w, ra*&' varied - but: did not - exceed 12.: krad. Experimental.;, and control -seeds LP ni khibiiy.'.Cdes- sa- -.'K-h: ark6v Leninivahi Xedabiek Kelbed-: 1408CPV f Sto' ISkI ~z ar,. and showed, a ~ d6f. nite:- relationship, bttireen the radiosensitiiaY r_p1ii1A8`9raVn froaltimidiated4eeds conditions.- -:6ult vation.con tions:fd' ~Iantis of. t e gen~ratiim preceding ir-. ...Furtherm6re, t~e- I di r h Cwd AM Wt~ AT50242k2: radiation"significaatly influenced the radlosensitivity oflseeds~-callected from them and so',wu under. identical cohditions.~It'is known that seeds of the same variety, ir- radiated ~at a different. degree of maturity', have' different radiosensitivity. It has ~also been establii3hed that different ecologidal'donditions influence the variability of. 'quantitative plant, characteristics (such as height of theculm and length of the spike) differentlj~ in- the, first generation of. barley grown tram irradiated seeds. important differences-in'thede indicesarealso observed between control plants of thli. same v ety~:growh under..diff6rent conditiom-;. Experiments showed that the in- fluence of. conditions 'Of cultivation prior: to irradiation on -the, variability - of these quantitative indides-is ma ifested, fairly clearly and, 16'retained in the second gen- eration6 Anothe.r.part.of this series of experiments howed that the number.and char- acter- of structural - changes in barley during. irradiation. frequently depends on the ecological . conditions in which the plants. grev: prior, to and . after irradiation. The 4ariabilitj of.quantitative and.morphological features observed in- the first genera- ant ti6n. of pli 8 is. a, fucation of the 4ifferent iftturatlon.phase of the seeds frou vhich~ they _. Grev. Structural. changes in the.barley-spike arethereault of Irradia- tion. Thus it was determined that the, chara'ater of structural -changes is connected Vith the Maturation. phase of irradiated: seeds.'.; The, frequency and character of lethal ch1drophtlIzutations'In the necond:generation of gamma-irradiated barley clearly-de- pends qa~the oultivatioti conditiond.or:the,,first.generation. It-was shown that cul- .tivati ii hditions of the'mot r eve an ease 0 co he prior to IrreAutioit h in. fluence 6n.the frequency ofappearance and dharactet of lethal chlorophyll mutations ion. Agai ney,of appearance of chloropbyll imutationt ln~the second generat, n the frqque L'~ 5137-66 ~`EWT(M) SOURCE CODE: UR1267016510001032/01191 5 :AUTHOR.- '.wvzhdfti,`:, Ni, 1. (Correspondin mber AN SSSR); Gray gme, oavskaya,, B. e-, cademy 4,8 SSS -R' (In t tiWIZene tild Akademi ORG: 46saitut Of dineticis, A, c ence s i Lya haitk'SSSR) TITLE:: The%bioche icalcharacteristics and radiosen~!~of different strains _a d n of ammals n specie, m SOUR CR.~ SSSR:',- lostitut'genet'lki. _Trudy,~. no, 32j :1905,' De stviye ionizi **^ " - - - _ ~ ~y _, _ Iruy -usfichiii, izIuc'hem' ~ ' sti dtq~~ i zhiVotnyy.-organ1,zxhy. (Effe of'lonizirig radi- y.hara , t ation~on pljiiit",and.animal;irg~tn*nii.3),:~U9-135 ~TOPIC TAOSI, animal -physiology,: radiation biologic effect, radiosensitivity, 0 0 c ii~etAollsm . -r mo'se at P rabbit, guinea pigi hamster ~-ABSTRACT: E#erlraents were, -condticted. ith *.reht species of mammals and, w -differe .n,t. strains.ofthe savie . species .to.cion'2pare_ their ra -d1o sensitiv Ity and me Itabolic characteristics,' Male rabbits'. goldenL'bamsters, guinea pigs rats, and mice (4 Aiderent strains) aged 2-2. 5.,months were used. - After x-ray irradiation with dose "Tower-of.41 5 2 rad/min, the - LD j- of each experimental anfinal was determined, 5F Q 0, and 1hey, were arranged in order creasing radiosensitivity as follows: rabbits Card 1 2 JID!Ci 577- 391 4!)Q~ 1~ 40 Z 47, -66 L5137 4CC NRS kT6624246 (750 83.0 rad); ri'at's (600 rjid),- mice, Kryu 1~owa ya a. taln (563 rad);- mice,C strain-, (536 pad); golden haxnstera (5311rad);, mice, iBALB/c:,straJa ~(442 radh a5n guinea pigs..(400 rad). Ex:periments showed a higher level of 6atechol amines in the adrenals of more radiGresistant species and strains. (This difference .was more evident: in Individual species.) More radidresistant strains of mice also have '-a lower:jlycogen content in liver tissue. and -a lower blood-~sugar levelthan do less -,radioresistaht strains. Furthdrmore,.: there 'is a distinat difference in the charac- L., tee of.blood-sugar changes when adrenaline hydrochloride fs.admin istered. In more radioresistant micethe blood-sugar level increase Is leasA marked upon introductioi L of adrenaline hydrochloride. Irradiation of radioresistant mice intensifies changes in thicr blood-sugar inx6sponse to-.adrenaline. whereas inradiogensitive mice irra- diation first depresse6 this , reaction Exil& then intensifies ft In the spleen and liver Of more, radioresistant strains and species, proteolytic processes:proceed more slowly. The ability of proteinases isolated. from these organs to break down casein. Jimini W reased, natural radi6resistance of animals. The a gradually ith inc yeasons the correlations observed are -discussed, together with the possibility of :using the se - biochemical dikerences to asses s the relative radkmenaftivity c4 Oiij. art, has: 4 figures and 10 ubles. Vs, )DE.- LS/,$UBM DATE ORIG jRE3F.- S f -,GTH. REF., -007 2 _--mmommumm- Ma L 5 6 EWT(m) ___4 SOURCE-COVE: U17~67.a7r,.51,000103210136tGI46 AUTK0kL_KjtihdL 9. Im (64tresponding member'AN -OSSR) I It ii~.16f~:Gen at Les. Ace desty~of Sc Lance ORG. at SSSK (Institut'gemettkif'' net u Akedealya- nauk:,SSSR) TITLE ft~v t r blood con I t o.~ and' in vivo tedlosensitivLty of.pariphetat tu'6 f in tat I of different genotypes AA stsits. ~zn -gsnetlkL~. Trudy,,no ~32, 19 Deyatviye :SOURCE:;. stitut AaLz ruyushchfth' Lzluche a-Ly- na, restit'alln7y L,,zhIvotnyY.orgaULzKY ~(Eff act of ii, I' and.entuAl _LonLzL gradLatLdn on p *at organisms), 136-146 ,.T0P.IC'~TACS,:_,rkdtatLon biologic effect, radLoresistance, souse* leukocytes. "phocytej peripheral blood, It" is-:. demonstrated, ,that, the number of- leukocytes, In the 1 16 d'~ flafte. or al, -coladftLo i,.~.con -be.. used to a 0 an e a 'a e- a' u radioresLat'in 0 However', no, . ~.connectLon- was estab- eterm a, 4, L- C dr~bet d -Iiiiie- ivtenv-~:. i'ed b I oad Ind Lce s,. an 'the radLor.ealmunce of a xper sents- "-showed, thdt',~' sucv iv Lug'-- kriyukove aya,.' afte-had sore L 44"Priqr:~to LrrA stfod.~--t Ldh-died eukocytes Y the..'BALD c x tra a. 2, .,rv*re more -saiieroily of fteted' NJ ~vf b y -a tio -h hot L t an. - t a. d 'mtde~ dt;1tht ;CC *Br, f Ear'ence s Increased '~,-w*LtW 4' ec?e dl 5 a'- Lim tad Lon, dog&.-- 'Thkae Lat CaM 4/3 I . - L 9139-66 L 8239-66 ACC- N.Ra ATS024249- irradiated on.1the. ISih .'1,7th day of embryonic development, Maximum damaged to the.:testisfwas observed Inanimate developed from embryos irradiated onithelftkl'day of embr onLC developments This is due to th _~: -differontistLon processes occurrLnj,Ln~thG.tG'st4'G in just this:- perLo'A ~"Tho lowest'x~-rsy 4oses,-c&usL,n% injuries in the tastes for'Animals ~ irradiated In this Critical'- period wer .a 50--100 red With 56,rad, -these. Lnjiirioe-wer4i:obsecved*in~.manth-old-'mice, and-by i 1/2 months. sperstAtogenesis Was, ~ rag tored With a dose of 100 red, spernato- gonesis. was. restored onlyln..ths: 6th mouth and, the weIght of the -testo contLnuod-at &-.decreased -level. ~.X_ray doses-of 200 and 400 red :.caus4id Lrrevev'sible chan as Aq:Nouse testaist'' Anistals.irradistod, with 9 liz the -critical were.-sterLlse The R&E of yonic:p riod. f neutrons for: testei 'd 1 0 -:-development, as t. a. ur ng ;he period.of embry nLq In them case of both x-ray and a-decra&aes prop neutron Lrrij_LA.tL6n# the~:wilght -of -:one..tes.tIc1 ortl~8811* to'-thi'jozirabs ~of- the do* so Isee .?Lg., 1):~, fractionated period G:tes ItLeal'-eubryonte Aritadiii1on".-Injuir sis to: t~ to$As thoft-',cr, wom cuu61atIve*Q~-Ortgw ~actol-hasv 8,.bab too and:11,figurese,; (J's] -44 V. SUB VOM. LS/ SUNK DATZt ORIC RZF# 0091 OTH REY: 023 -4 :313: ACC NR: ATSOZ4ZS3 SOURCE CODE:, UR/Z67Q165/OGQ/G3ZIGZG6fQZZZ AUTH01u, NiAdLa o I* (Corresponding member All-SSSIE); ORGs.:-.1natitato--of GeketLcs, Academy'~of:ScLance_a 99SR (InstLtut gene-, ttlit Alkadea W: Sault 555R) -f fect~ of. TITLE v 'The~~' protectLvir. subsiancom an survLval-and changes- in, anw, of.:-mica of ~vavious after X-Vsy~ r -rIad f ca b ig noxL4' tatteM. 0 fact 'd t an 0- a $SS -R 111stitut kenettki- Trudy 32 1965. VeyPtVL ~~;61!gcz: A Goo yo A6iitzlruyushchikh Aslichonly, n&, rastitelon7y: L Zhivotn7y rManiziny, _-of.I_4-aV**LA'g_~ radiation on plant and asLual argauLsom). 9 206-222 _(Jiffect tA *0PIC TA T - a 1, a IM biologic ifte nt ai -phystolo adiatL" C gy, X ray _ArradLatL ar noudev xLdeq Itwer,,thysug gland, 'so Isen,, carbon mono o ABSTRACT: ::Dif fe'rences-be,tw4mu thiw off ects of carbon monoxide on two 4itteltent '$train# Of atcoi - Irra atod with ~the:, same' does of . x-ray& vs. a arialued, Nale of a' of dc, Zi (radiorisLstant) and C3H, (radio- S7 Mal strains were:uss rso tive: do These straLus are'also characterized by dif f it' iuces.~ b4ody: weight. and tn~tha-WoLght of certain- organs --w thymus a vors~,4pleeug and tastes--whi'ch wisto used --,&a indicators of the radia- sn 191 Mu COW: Ift ACC N14 ATS024253 tvin';iffict i A-radLatsd with x-rays In a ~~4 ow,2-0'5~ months. old.verw r dose of-- 0 6 0, -radwLth Adoe, powar ot -74-75-~vsii/ In. Experimental A a sted, -in, art -atmosishere of 0. a-- &at s4ave,_ rz dL .5z__ carbon monoxide; co t ro I a "We vs. Irradiated In a'normal:atmoirphere.. Results showed dLf-. ~f r ac -the,, IL of thessALfferent strains as I&,-. -morta ty tate..whan :Nice, were - L ad irith, Co As a protectore , IrradLat Lon, wLth.600 rad FradLat ~,caused ,dea'tik,-..ts-only~39Z'bf.'~nicig:,of tho.,radLovesistant' strain:- (CC 5750 protottod-W t 4 Lth4:?4Z:UorU1Lty In. the cointrolsj compare v SIxt y-wu ne:pii t dUthe.radio a one Iitiv a a I orcon. ice, (C3H) protected,',with ~CO'Aiiidq as' '-age ILast 9OZ of T. the: controls,*, -.It we* -noted that with the _Use:-ot~ C866i:, itonoxide all a radioprotectdrt unlike diethylstilbestro.19 U-Its thw c aracter sties of the %strain Influenced th - r a as -of irradia- . plistfid .,of: protectLon..o. the.- th,this dose Ignt organism: wL ii~~04.-41- f ~Vd f Ov. CjR: U c4- WItWCCS73r m ca 23 01v s75r mice band - 01 h -hematopotetLc systems, equally; to protected t 4, gastr Lat stinal and, ~the 'other s t rAt' h tive -of fect of CO was more -~howaver or. in-t a ptotec tho,~ gastrointestinal system Both! .,with and vithou evident: an t the -CC pro toctAon 'of carbon monolckde S75r.iLce recovered. Lost body weLght so vi rapidlj~ " f tit r'-- Lrra dL& tLoa _thani~~: C jH iiiLce a S Imi to r a -data wore.ob to Lned.,~ f ii, p-rovioud- itzparinatits.-wLth.dL4ithylttilbes,trol'-- For CAULce -thymu& glind~too'k:~Jodger.thau for CCS73r aLcee ivy. Once &'&In cartion.:mbnoxIde had no positive of fedt an thyatus- recov t'fiesd ~-rssults as .re .a_wLth:_results.of other .4zoarisents by the authors, 'C k,-u-A 4. ACC Me- AT5024253 Lit, whi ch.,,. the I,ack-'af E act on th thymus gland specL Lc ptq1tactLve eff e -VaUno 4 an's .4ore I he- use of h Lvil die thylsi tLIbestral tilt L t 1~i t*-csrbon monoxide -as, a, pro cc ove~~ Exper man a , tit ,ults, 'a so: showed t a -reduces ovoicoulponfeiLon of -'t'hia veLght of the livot'afte'r irisdistion with-,600 red 07 the 21st 10th,day.afterivradtation). The reaction A' oVth4.s.:ppl4eu_to- rradiation in a carbou,nonoxide.atmosphere was iden- t ca to-r ~ U44', traLSO-OVOice, - In, ICC57BV. Isice, Protected Iwith CO, a sharp iiiiiiamAn ~ the w4L~ht ~ U, 6 renai a served n the 7th a toad.. .16''Was b 0 after rra LatLon V on 4tothyl4tUbestra was "Gid.,so the pro- A ay L ta .Ctdi this: V,hon,oaenoa -was - o6soored -an thit_Iud~fth day &f tar -irradi- atloue.~'_It wash noted that- with 600 red of z--!rays,, CO does not, affect the :~iiaaIas,44, volahi, of the testes,*~ .. TbLs.lackof protection was also .0 sorvod'durtas.irradisiton of ufts.with the use. of diethylstilbestrolo OrL art fiAs s: 12j Lau rite. -and:!) tablise-~ Suveonst LS/ SVSK DATZ a' ORIC RZFs diot OTR.~IIRZFS 014 act QW -313 OUZHDltl, N,J.; NIZIMIK, O.Y. Spermatozoon prouv~tion In rabb!tn U- -m gi3rjiiti,~ 'La"lurlto tvAutiod by irradiation Ln v-~tro. T--udv rhat. gen. no.32t220,-237 ",5. (MIRE 18tlO) NMHDINA..,N.I,.; KWUSHNOV. T.S. Nattare of the effeat of gamia rays of varying Intensity on the frequency of the formation of chromv6amal aberrations in mamma-lian liver cgllo,, Trudv Inst. gen. no.329257-265 165* (MIRA 18-10) IT~*ZHLIN', FILEV, K.A. Re7ation between tre, rMe of tens ty of s,~ea rrad bit icn Lind the; r humiait MO nc-1:224-226 .,--a 16-). I 1. Institrt. genetiki AL i ISe! I-ral Inaya che3~ayu iab.Dratoriya, Scfil.,ai, Elol-,,mriva. SSSR (for ,L5 2 _4) - 6 6SiT(l)1Ei.1T(m )/T J.',, NRs AP6028672 SOURCE CODE: UR/0020/66/166/005/1217/1220~ AUTHOR: Nuzhdin, N. 1. (Corresponding Member AN SSSR); Samokhvalava, N. 3. 0- ===Z_ ORG: Institute of Genetics, AN SSSR (Institut genetiki AN SSSR) TITLE: Comparative an4ysis of the dependence on the physiological state of seeds of chromo,some, mutationsWinduced by che-m-ically active substances and by ionizing radiation (gamma-rays). Iq SOURCE: AN SSSR. Doklady, v. 166, no- 5, 1966, 1217-1220 TOPIC TAGS: biologic mutation, radiation biologic effect, plant genetics, plant reproduction ABSTRACT: Barley seeds in a state of enforced dormancy and organic dormancy (cf. N. I. Nuzhdin and R. L. Dozortseva, Izv. AN SSSR, Ser. Biolo, no. 5, 679, 1961) were subjected to the action of gamma-rays or of one of the chemical mutagens ethyleneimine (EI,, N-nitroso-N-inethylurethane (MIU), and diethanolamine salt of maleic acid hydrazide (HMA). The results obtained on irradiation with gamma-rays confirmed the earlier finding by Nuzhdin to the effect that the number of chromosome aberrations produced differed greatly depending on whether the seeds were in a state of enforced or organic dormancy. The number of aberrations produced by gamma- irradiation and EI was greater for seeds artifically brought out of organic dormancy and germinating 10 days later than for seeds treated in the same manner and allowed .5 L 38250-M ACC NRt AP6028672 to germinate without delay. The same difference, but to a lesser degree, was found for seeds treated with HM, while no effect of the length of time elapsed before germination was observed in the case of seeds treated with NMU. Upon the action of gama-rays, bridging and fragmentation of chromosomes occurred in a ratio of,1:1.0. This ratio was 1:1.6 and 1:1.4 on treatment of the seeds with EI and HKA, respectively. The results obtained showed that the mutagenic effect of gamma-rays, EI, and HMA depended to a considerable extent on the physiological state of the seeds. Orig. art. has: 1 table. IJPRS: 36,9321 SUB CODE: 06 / SUBM DATE: 29SeP65 / ORIG REF: 004 OTH REF: 014 Card 2/2 MHDIV, P.A.; ROW KIN, P.D. Nothods for the determination of peptic activity. Zmb. delo 5 no.l., 3-4 ja-l? 159. (MM 12:3) 1. Is laboratorli kafedrv blakhImU Omakogo veterinarnogo inatituta. (PVSIN) ffmim, P.S. All-union Communist Party work Political activity in the collective of the Kamyshin forest conservation station las. Khoz. No. 5. Kv, 1952 9. Monthly List of Russian Accessions, Library of Congress, Aup I ,ust 953~2 Unclassif led. SOIN, A.; NUZHDIN, 7. Work of a computing and business machine service center. Dan. I kred. 17 no.8:62-65 Ag 159. (MIRA 12:11) 1. Glav"y bukhgalter Daepropetrovskoy kontory Gosbanka (for Soln). 2. lachallnik mashincechatochnoy stantaft Dtiepropetrovskoy kontory Gosbanks, (f or luzhdin). (Daepropetrovek-Machine accounting) NUZHDIN, V. Transistorized millivoltmeter. Radio no.3:50-52 Mr 163. (MIRA 16z2) (Voltmeter) BOLISHOVY V., inzh.,- SIURNOV, V.; kq~HPI.Nj, V. Automatic device for measuring arterial blood pressure. Radio no.601-33 Je 164. (MMA 1711D) ACC NR, AP6035940 SOURCE CODE: UR/0413/66/0oo/020/0199/0199 '!INVENTOR: Zemlyanitskiy, A. N.; Karpovich, B. K.; Motin, 1. 1.; Stolvar, A. I.; ,~~uzhdin, V. V.; Ponomarev, I. V. ORG: none JTITLE: Centrifugal blower water separator for aircraft ventilation systems. Class 62, No. 187539 I :SOURCE: Izobreten:rya, promyshlennyye obraztsy, tovarnyye znaki, no. 20, 1966. 199 ITOPIC TAGS: aircraft cabin environment, aircraft cabin equipment, centrifugal blowerj j ;air conditioning equipment iABSTRACT: An Author Certificate has been issued for a centrifugal blower water iseparator for aircraft ventilation systems, consisting of a housing with intake :apertures and a nozzle; the housing contains a rotating drum with radial blades and ;has openings along its outer surface. To simplify construction and decrease its sizej ,between the blades and end wall in the back portion of the drum is mounted a guide I ~arranged to direct the flow in the opposite direction; the guide channels air into ,CLLI outlet duct, which is located along the blower's axis and fastened in the forward :part of the housing. :SUB CODE: 01, 13/ SUBIX DATE: 06Nov64/ UDC: 629.13.01/06 Card 1/1 66.071.7 137-58-6-11326 Translation from: Refe~ratt~ivn zhurnal, Metallurgiya, 1958, Nr 6, p 10 (USSR) AUTHOR: Nuzhdinv K. TITLE: Ways of Increasing the Extraction of Copper and More Exhaus- tive Utilization of Ore Material at the Tur'iiisk Concentrating Mill jPuti povysheniya izvlecheniya medi i kompleksnogo ispol'- zovaniya rudnogo syr'ya na Tur'inskoy obogatitel'noy fabrike) PERIODICAL: Byul. Tsentr. in-t inform. M-va tsvetn. rnetallurgii SSSR, 1957, Nr 7, pp 8-11 ABSTRACT: Investigations performed under laboratory and, in part, under pilot-plant conditions, with ores from the Tur'insk group of deposits shows that Cu recovery may be increased by the use of lime in the comminution cycle (10-30 g/rn3 CaO), while py- rite and calcite concentrates may he obtained as by-products by the flotation of Cu tailings, and,low-phosphorus Fe concen- trate by magnetic separation. Process diagrams and procedures selected under laboratory conditions are adduced. L. B. Card 1/1 1. Ore----Processing 2. Silic acid--Reductior, 3. -'res--Flo~a-.ion. AUTHOR: iuz-hdir., 11.i[. - ------------- L--- TITM, Use of C'Lre.-lat-~rq. W,~;ter af-, a Lleans of tlc C.-,SL of Flo,~v-atioa-,lConcei~tr-,-,.tes (Frimenenilye oborotiloy vody ut, VL srizheniyu sebesto-'mosti flotatsiom-,ykh :contsentr-tov) PERIODICAL: Tsvetnyye Metlall.,), lc)':"(, '10.1', 13 (USSR). 1 00 AFSTRACT: The auti-oi descilbe- wur'f~ car~Jel Dut jointly td- the Uralmekhanobr ox~_,anisati._)n and v.,orkers of th~e :nd production jJant at t.l.e SredlleLlrcal'Sk COP~)er-SLeltiDIE '03rkS (Sredneurallskiy medeplavillnyy zavod) to cor.". are t`ie chem-ic--! and tecllinolo.iic~_l pro,ertlG_L~ of fres- and ~-.faste -ater a t h E 4 C ~-orlLs. The aii- ,-as t9 rcduce t --e _ise if f costs 14 Kopeks per rii ai-d of ,-...ici. '.92 m -,.vere '-sed ii, 1~"~)C per ton of ore trc.-ted. TI-e results (Table 1) Indicated tlf.at waste water is s.-,tis.-Lactory for flo' -_~t'jn of co ,-.,er T'.. e author describes also lc~' .-.r~,tory cxpe, in -ch 'Ul-e vlor, flotation scL'-.,ei.,.e adc,~tcd usin, frcsh a-ld -.,.,a_-tc .-.-ater --,-n diff~--nt series: e r--2ults of t-,--e t--.j serie5 .,.crc s i 1 ar. Rcco=ncnded co-ndit--ons are sa, r a--d she-ts Ll.lef_ Resultq obtained they weie - _,ced arc d,L;criber~; ti-e-e showed no deterioration --ith i:-,crr:;._~3ii4_ r,-c'Lrculation. A-uai,yses of tl..e ~~,nste viater a,, v rioi, sl~a,c~, arE. i-di- C d' 1 catinG appreciable c1-anLes d-- -:--at, 'ovev,,-_., affect U-ze of CirculatiaL 7!atr--- aL a Lea-,-'s of Lo%,.,crin. t.'-,e Cost of Flotational Concentrates -lotation. The e=perimei-ts v:cre carried out with ores c;f t'he Degtyarsk deposits aad ti-,--- eneral conclusion i-s tLat v:-'th sinGle-staL.e flotatIon carse cop:.er concentrates with 7.25% Cu (recover5 '/5.61,6, .,.ithout allov,,inE. for copper intermediate products , easily .-,urified v)--*th activated charcoal. Data on materials consumptions are Civen, together with estimtes of costs made by Yu.I. LIJIL~chal'skiy of the Wor',,~-s. There are 6 figures and 5 tables. A6SOCIATION: Uralmekhanobr AVAILABLE: ij if (;., uq-7,--,L 2/2 1. Copper-Smelting 2. Water-Contamination 3. Water-Control systems MT., q PYATTGORSKAYA, G.Z. ~_Nffj lq$,M~ Ways for the complete utilization of copper pyrites from the Khudat deposit. TS-et. met. 37 no.906-10 9 164. (KRA ISO) .,. 11MIDN' YU, Fourteen days in Japan. 114est. prm. . i '..1,ind. promys. 2 no.6:36--t37 Je 161. (MIRA 14: 1) 1, Referent TilontrallnoGo komiteta profmy-t;m raboc' Vd. mestnoy promys! lennosti i kommomllnogo 'Adiotyaystva po mezhduna-rodnym si,7azyw~.. (Jap,oin-Peacription and travel) ITIJZHDIIIA, G. P. and GOLDM V, L. ff. Go=cerning the Isomerization of Ethine Diphthalide, r;;,t,-o 1275. Sbornlk State7 po o'bahebey khtmii (Collectlon of Papers on General Chcmlstry), Vol IT, Moscow-Leningrad, 1953. pages 1680-1686. Ural Sthte U Iment A. M. Gorlkiy NUMIDINA , L. A ; POPOV I V. S. ZI Device for measuring and registering corons, losses electric power transmiesion lines, Sbor. rab. Yop. noo5t287-298 161, Corona (Electricity)) Eldatrio power distribution) 3leatria measurements) i in high-voltage olektromakh. (MMA 14:6) NUZHDINA, L.A,; CHEfFSHEV, V,Ye. Voltage limiters for pre-renting overload of instruments. I=. tekh. no.3.-41-42 It 162. (MU 15:2) (Voltage regulato,.i) L 60211-65 EVIT(d)/EWT(l )/EEC (k) -?/F_EG-4/EEG (c) -2/EED-2/B,.A (h) Pn-4/Pc~-4/Pac.-4/ Pae-2/.Peb . GS- ACCESSION NR: AT5013569 UR/0000/64/000/000/0212/0222 A fCandidate of te-6hnical-scienceo T R ovSkiy's, X., 0 -Nuthdina,': -Popov, V. S. L. A. -o -o C tear' re$ :9 t' 1 961 lat on -perld ~VITL daver ance Into :e ec r c 1:k 'S6URCE.:,ANSSSR . histitut elekiromekhaniki. Avtomatika, telemekhanika 1-* 1. priborostr&veni-~e (Automatic control, re mote control, and Instrument oxture).._ 'Moacow. Izd-vo Nauka, 1_964, 212-ZZZ manuf TOPIC TAGS. con"rerti- r',t elernetering, tel6metering converter, resistance ire uen2X- cony rters janalog.converter ABS~RACT: A description, an error analysis, and the results of an experimental! investigation are presented of an analog converter (a laboratory model) that turns q electrical resistance into a proportional period of a-c oscillations. The converter 'includmi an, RG generator, a Wien bridge, and an amplifier. Two frequency- 'dependetit bridge arms, which constitute an L-shaped quadripole, serve as a positive -feedback circuit to the generator; the remaining two arms, an a _7 L 60211-65 [ACCESMON NR: AT5013569 ve e a- 0, cii-c it. -as a nonlinear resistori, negati 4e db u A 5 thermistor is used A- linear relatio- n between the input resistance and output period is claimed. The -_error, at high amplifier gains, is largely due to the variation of capacitances in ,the Wien bridge. The deviation of the output period, when the converter is used .as a thermometer, is determined by tho temperature coefficient of the resistance thermometer and by the measurand range. The possibility of attaining an overall I system&tic error of about 0. 1% at an ambient temperature of -20+ 30C and a supply --voltage variation of 10% io claimed; Orig. art. has: 4 figure a and 123 formulas. A SSOCLA TION: none OVAMITTED: 240ct64. ENCL: 00 SUB CODE: DP* EC NO REX' SO-Vi-005 OTHERi- 000 T NUVIDINA, M.I.; GESELEVICH, A.M., Prof... red. (flow surgical apparatus and instrumerts and experience in their use; bibliographical index of papers o. the scientists of the Scientif4.L; Research Institute of Experimenta-1 Surgical Apparatus and Instruments] Novye khirurgichaskie apparaty i instrumenty i opyt ikh pri- menerxiia; hibliograficheskii ukazatell rabot sotrudni- kov NIIEKhAI. Moskva, Nauchno-issl. in-t eksperimentall- noi khirurgicheskoi apparatury i Instrumentov, 1961. 47 p. (MIRA 17:9) GMOVA, Anna Samilovna- NUZHDINk V - , %Fppjt#JjjQb * XACIIKO. 16.1.. k; -&Z, ##~J&VaXW4 retsentent; XOGAM, A:W.. nauchnyy red.; ZAYTSBVA. T.N.. red.; KPbDVAM, L.Ta., tekhn.red. (Chemical finishing of footwear] Khimichookaia otdalka obuvi. Koakva, Goa. naixchno-t~khn.Isd-vo lit-ry po legkol prmW9hl.~ 1958. 199 P. (Kin 12:2) (Shoo manufacture) FROSKURTAKOVO R.1,; RUZHDINAp_T-,.U. Proteins of vheat germ and their enzymatic activity. ALuch.dokl. vys.shkoly; biol.nauki no.2:148-152 160. (MIRA 13:4) 1, Rokomendovana Imfedroy btokhimit rasteniy Mookovskogo gosudarst- vennogo universiteta im. N.V. Lomouosova. (WHAT MK) (OZYMNS) SALMAROVA9 L.S.; GORBACHKOVA, Ye.A.;_V2P~F4, T-.Y. Methods for determining the activity of cytolytic enzymes. Trudy TSentr.nauch.-issl.inst.piv.,bazalk. i vin.prom. m .9- 53-62 162. (MIRA 16ilO)