SCIENTIFIC ABSTRACT OLAH, G. - OLAKOWSKI, T.

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SCIENTIFIC ABSTRACT
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k -4i JIGAM/Organic Chemistry. Synthetic Orgazic ChmIstry. B-2 Abs Jour: Ref Zhur-hhimiya, 11o 6, 1957, 19292. Author Olab Gy., Pavlath A., Elhn 1., Eerr F. Inat Title Synthesio of OrCanic Fluorire Ccirounda. XVI. Prc!para- tion of Fluorine Derivatives of Pyribenzamine. Ori g Pub: Magyar Tud. Acad. hen. Tud. Oazt. Kozl.., 1955, 6, 110 3.4, 327-330- Abutract: nethods of s~-nthesls of fluorine eerivatives of pyri- L.-.,izaminc t .pyridyl)-ethylene- dir=ine) r-re develcped. o-and n-fluoropyribezaninea (I and 11) vere dbtained and their antibystanine activity was compared. In a Vainea-pig) I Y of byatamine noutra- Lim the action of 0.05-0.1 \/ n-fluoropyribenzamIne (111), 1~ 11 and 10 Y 1.1, 110 111 are lesB toxic, than other baoid sastituted pyribenzamines. 0.1 mole VpV-41ime- Card 1 1/3 MMMM/Organia Chemistry. Syntbetic Organic Chomistry. E-2 Abe Jourj Ref Zhur-Wmiya) 31o16) 1957) 192829 thylethylenediamine is boiled 12 hrs vith 0.05 mole A - fluoropyridine (IV),, from the filtrate is Isolated 11, If- dimethyl-N'-~ A -pyridyl)-etbylenediamine (V), yield 42.6~ bipw 150-152 /25 =- To a suspension of 0.19,10 110H in 30 cc toluene Is added In "_ a (stirring, 105 ) 0.1 mole V, boiled 2 bours, -tben at 50 is added in drops 0.09 mole 04%M~02Br, on cooling 10 cc vateris added and from the toluene layer and In Isolated 4 g. V and 1, yield 34.5-j';' 001)* 165-1750/3 =j mnohydrocbloride, M.]p. 198-2W0. Ara- logically are -obtained: frcm n-NH4CH'2Br --II, yield 40~ b.,v. 148-1550/1 m; monobydroeblorldej n.,p. .145-1470j fz= n CHrr -.III) yield 56.4. o.1 mole n-NH4CHiH 'n6 b ilb.d 8 bours vltb 0.05 mole IV, coo ed the "fid (V'Z) 11 mass Is extracted vItb 200 cc n-bexane, the bot solution Is filtered., andafter tooling from the filtrate crystal- ize n-fluorobentyl- -aminopyridLine (VII); vitb the =ther Card 2/3 ELIJIWY/Orpnic Chemistry. Synthbtic organic Chemistri. Abs Jour: Rof Zhur-ilizlya., vo 6, 1957, 19282 liquor the reaction mas Is extracted two tizeB movi, yl-ciding VII 831,')., n.p. 950. To a sunpension O.O.J role VaOH In 40 cc toluene Is added in drops 0.05 0mle VII, boiled with Stirring for 3 hours,, then at 50 Is added a so1vtIon 5-4 9- (CH3):)?7CH2CR2Cl (VIII) in 10 cc tcluer'e, b,~iilea 6 bourn, frora the cooled off filtrate is obtained 111, vield 58.&;. 0.1 mole hydrochlDrl,~u VIII is boiled :ic-x-s witb 0.2 -.ole VI in 200 cc toluene, slmXen with ~,c 611 uv% is obtalmd 11,11-di--ct.,.yl-lll-(n-fluoroben2yl) -othylence-innine (IX), b.p. 132-1340/12 =., Yield 321". 0.1 mole IX boiled with 0-05 role Mn 25 cc toluene 5 hours As shaken with 30 cc 6n ))son is obtained III, yield 61-%- Part XV see RMOAm, 1956o 39629. Card 3/3 , V I , ME Lrjl) (cf ii. CA V.. 3 s ir M, rund Is ;..Oil InS ~!l c Ck it f u! 0,111 floorill't (011~ ~"I %lovo I mt'i~ it -_- _'! i! I , 1, U I tyle, 'd-11- .1 w, ~; 'o." "I, .... ...... 195.1N1 2 pit Gf, rl~t "IrT, 1. W, 1 i.v I I. 1wtv 'VWA(tw'A by r".'tucitir tiw _cA- fluordwritcut-S with Ittle and 11111toollia"I vhl"IH'~ 11% 10-rhi, ! I- I _- t"-f ........ 11 1,0- 111. 0", T, 0 11 1 ... ... It Lill 11. Az% of I, Iv) ..0 tn' fht-" ph' obtjaIn,,I fri-Im al;fflrle~ bi way A .1;Iphut 11--fIgA iny. If, mc~ -)v' 1; I- I vn- b) thu lixtIp.) cf, Imol.-f.iI iF~ c.~U at 1, qI at -4-ti, "ar Itior, (7 L Dintri 4F,2c Slatheflis 0( olganic flumine rompnuf0s. x1f. 0~ of fluorobeuttae. ("All A Kslisil. and Gy. Var&6uly -MmL T -krian Amid. Sri., Thi j~,J) J,1,4 FnAlih); cf, CA. ~G. jj'~Iyj- wal nitrated by the I'Al"WinK wcv'-~" ~ '1I.A the prop(wtion of FeJ4NO, L;LxIIcTS k4lit'd it, I& fna.l tj'- Ultmvialet afmnrtion opectra rcagcnts' 'I'a 'WT, t0i,f) 4.1 rmetiou, and % jl~, o-, and intmets givm~ (%p. gr. 1.41)and M g.concd.1fSO.,84.5. -10',W,S,-; 40 X. H.S0_11jO, 25 g. &)01 11.50., and W C. N:040,, A-5, (*-7011. 90 a I - 'ACON6Z 71.2. 0*. 96, 4. -; DzON('h. 004, COZ4, 100, -, -, Mi + NA. 03.8, m4A, 72, :N. - Hqutd N04, - W5 C. from :N1 It. trmsm lcmp., 79: 111. 8; NA Yapor, - (4 f=t 14 g. W. DO, 10. Took re2czinns give tArgcly p4.winicrIL mfx~l t y j~el~ --T'Die presumably give 73-8% p- and 10-28170 radical type mechialm 907o o- &M 101"'D m-Lwmncrj. MM(NOO, (1), bm 153-6", was prrpd. in 4917, yirld fmm 67 1. PhP with 70 g. HkOj1fO and 75 C. fu hl'~ M N('h at C.11'1" - 5 to 0* In 24-817# yk-M frocn 10 1 g. 2,4 X-1 (NO'), in 1(11 -20 Ig. dry KV. and the prmm reptAtcd 3 timel" I%I:-j in 79,8% yield. m. 24'. fron) 4 g, PbF rrAA--d and A irri'l with 0.5 a. NA added in antall p-,Ttions. I (I I ) atiil~i 4 V. 60% olcuta at 0* with 3 It. U.S43,140 and 3 F. runzir- 11110~, the mirt. heated to 90' 2 lira, and to Pb) 10 hrs.' coolled, and poured outo ice ykMed 30% rym-FC4!1,(NcA4 ta. 35'. Fnnbcr citration of 5 It. I with 5 g. NA . Pu!~Iyt nrTS4 is :,4"" M A C"f,*jL J*'11W tlt~~14!4i,li ij;~1113 ;f a Al''livil 1'r VI. I,, fi-f I)J;f v 'A C. X111. Vclirali-~d C.1 jllt'i~;~~':hjl~' O"kh, Amil 1"VE'oll' CS'.4 I ti, C A . 4 9. 1 i, 5 1, 11 !1- 1 ~i bl'ahjas, R'Nift OicliIIII!, iq f"'J-1 t:~ MoIr CICIVCHAF (1) 1') 0 R I'll, ct " ~''l a J~tp, n1L,*~wg i~, wht, 1,) --iiml o%rciright. III, t"allal OK ;11?) clv'f4. 11, 1-0)~ c-AfeCill.. ~"V;4r' 0!, 1-4*, CN-III; P- 'Iff V%. 17 -15'. FU16; 0 64 . 'q; P P,, .11., t-1 (Wf" hexane' 111- tP N cl~~ N(-,If" 1(11~ Etoli, fl, (Trjl~iv r-. t-~ '. . -j JiC411, Ft,011. 'JIL-2" 81,1; j 3 124r--5* (Yellow), K1.7; .-P i7~1;; V4! 4~ 'c "(..C"), 'i 83 121 -1. .fxtAyWivrdAax. 91-2: 4 Sjnthcj;j of Of9an"4 Z-Jlvoro~hyiu rvj)kj .68-9., WA. With esterase bi,xLg agents (eg. dj)-o- Propyl fiuorQpho%phnfe). toxic doscs of them cotuvds. ad- ininistcred to aninials pfoductd no toxic Fymptonns. The compds. are being tested as growth inhibitors for rapti. cancerow lumm. Xy. Decomposition reactions of de- tire tires of fluaroacc tic acid. GyOrty0lih.Attilaparlith. and G t "I lbid. 451-3.-Fluoroacetatti (1) r withM& give the flumoacetsmidt whose 15% 1110 sola. Is stable. This v31n. treated with thlw;de of li-be Hofmann rCQCtWD) dtCMO. 0~1 plettly. 2-Fluoro-etbanol 11) is also completely decompd. an i0k. (midation witb 1 cWt.wideoflime. Diol.cffectsoffandfliresimilar. MI. Wepamtion (if 2-fluor"tbylarafmo. Gy6rgy OlAh and Attila, Paylith, Ibid. 461-1-Set C.A. ", M542o. janet U. Austiopo" 4 t7 4"P P;N M k.;4 or tj Ilk. Ut !WL BMIWM/Orsanic Chemistry. Synthetic Organic Cbemistri. L-2 Abs Jour, Ref Zhur-2aiiniya, vo 6, 1957o 192B1. Author : Olaboy-r,~vlath A.) PAjor Gy B. Inst : Title : SyntbeBia and Investigations of Fluororganic Coqpcundo- XV. Decoqposition of Fluoroacetic Acid Derivatives. Crig Pub: Acta chim. sead. sci. 11uns., 1955)'T vo 3-4, 451-453. See MhMim- 1956P 39629 Abstract: r1o abstract. card : 1/1 A 1A Ypzi " w l "', 'V""S3 st:p-t~$. 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I+-,- lily, oofi it 41' V C.P, 0 8 it -ilk 1, 0- KOO" atc ~tduc fih"~d ld, -WO ip tv4i R- W VTJ m, k- 4~o ~N-. A'Lo'~ " til3M'JE~~ LVI&E L500 14*0 p" V V of KOU. VU V41 hodi"m it v r A. lit V~r J li('Ar if, JT..t- -L' j; i-f m b" '.0 fE?~ "TO -&~d to M 6N, I lydii,lFtnis i a ~Sajmu~ di%il4v t,, th. o.i-i-v-.~-m J YZI I., X M Fr-mfWma- 46 r .11by'l W~ V V lip, .4,1~1' 0- 1 M '01 ~~Ul hall, ttw ww q 1~ r 'f t) w A;'c aud t' 'fl -ay w4iw~ .~f ib 194 g MCI., 4od Ch. railtj WWW-j Cq;'!' W*' -f~d L-W -1.1 .01. lbir -OAr-4 A# i~j'mv ! ww-jx%j t" fj (I Itm. xtm-m ap-0 ths dbtWa!n "t"W so k.0 2 # Ul i *') 4 "t'1 ww% �~V' a4 -mD1 .$9, - amt W&.IW4 th rwxo trup'. Omwo~. puft-4, rmv~ ke raW w4h RtA. seed It* HhUsalm. dbtii. fiviu, 1 5 A iff I& 10 1 11 F, ftm*-A. to t!~lat 7, g I (W;~U(A'y -'VA~I-d w - I ') kz 10&6 t n ~h" V-1w to I A. f~jw-f tW vv~v 13F. 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P-eivetitwi;A1 bman tdflw~rkk 'I fI-.ujd4T! at liquid -air Eesupe%stwx Ylkkw a coolptot Ar 0&00 by it& ratedvity thig czuIplex xpfu~afid to 6w An too I h 9flikik tm titc Nbrmtw of *:AY spattipg 4-%tirILIA 'file -titte-tuvr 4A tht compttx 6 of) repTeu'llt-Od ~)i Ok ~~Jrlmlim WILb fbe AW (4 06 odupwx Yhrimix aloalkstiv c(9r'..'OUA(h Oakh em on= the rmctUxI (A, t6e 6j4t~" witix iovahu~z die cc OT aryl -'gMmItim Wagenidet form-'alom al I~Iw ON !M"~An- 4- 11 ) 04,o9,;?, U~ EUNGARY/Orzanic Chemistry. Synthetic Organic Chemistrj. G-2 As Jour: Ref. Zhur.-)Wmi~mj Vo II, 1958~, 36288. Author Olab G., Kuhn 1. Inst Title SynLhv-3is and InveBtigation of Fluorganic Substances. rAI- Synthesis of Acetuldehydefluoride and of Aliphatic Fluoroxetbylketones. OrIS Pub: Magyar tud. akad. Ken. 0B2t. 1021., 1956, 7, NO 3-4, 481-483. Abstract: flo abstract. Refer to Ref. Zhur.-YhiTniya,, 1957, 63581. Card .1/ 1 XIV 1,14 0~1*pirr4,sl nr j~110m~l-WhOM- rt-mark* ~,iztive ti s now P7 Op#rj%tjUn Of t~~ Wyl tsual i'It 20" L- f "tkw oy A AK MR1 7".- mm- liw4 t.; .;k~ ~.u~ C~l i., Hame, tt~c. %Nv .4 By, 4"d PbMe, Ph,?. PbU, PUNOi, A- 17 Prspo~ ~- i ya 1-44 0.1, t1i Kbtlix, smd llivin Fifti'l A"7 , -r Z T~ 0, peg), 4j. C-4 Sol IMA24. -RCOF "I m~46-.d mcihtd 4 Newovvaiwi anti A.-In Ic ~O-Jtld Ir ) ronlz RC 0 ?7 mrA~ I'lir., flc ltzi2-- h,-Ikt.-d l4owly on w water "Auh !(" at s~ loul: and 41IZ7 j lAr. htAtb',j' rthtd.. KI, u;f -~he f'Alowltx I Al onk'.%ad b.p givW~ H, FI . S. C. Pr, sde~clj. "'v fl, ru- 2'. Dtt' M.6 Kit 41 V"CllCH" 04.A. 'VP- I A m. *7. U; 1 -13 * ,I hr 1'0*' 69 b, R8- 4; i. Cdli' ! " El A t JV) t"' 6!,-: Uq (i 9. at Im, -7W C'f~' 1>'t :'&-im -$11" , ". h" m 180- W) U. b,, -'51. C'F" 2h," - m, -68', CH.U. M-". M -6". S-A -f'; it - [ at )e.3.6, and lutviv air t,~rtj.A fj~ the rftu-u"~ "f 41P~; .% In 1440 .1th h ' addins &;I% 'rd il~* nuxt -~3ui'jm' t!lv'. t~ldmc I S t~ NaF. Ci" qtivt oo'O~cr V4 bol- oad Itftmolwaly dittl it III tu 141-.V*; TtmOrg &JP.C()P wub 1,4. C. OWN-t, ~W 411 n 6 r R F ~wl- mg u~- th, mix-. an beitnit jgi~-r Ifec"rif-T 1, 4' :10 1 Tht lo-i"ww. ~t~ 77. ,;7 0' ii!, .0, P" 4b 4'~w 114 40'.!9 114, 8 W1 re 1r,4qjo with bdu fluioAeurl + W"mri 'K u.,111 ~ '1111(tKill 130 -NA, jfi. PP, Ai6 71A 14,W;. i,~i, pa-i,411ng R', Ov I q lr2~ W.111 BF, at Olt i4ir kw flit f,ATF4vx a-, 01C Rk ~01~ ~iz k~,t cvi,~p to rt- o, -'It , wl tvmtm ~IWJI- :fV ~, -"j)4 ", 1.~, I r ~-',Jnq :, g Plihic w,,rmius A~-.is Io t HCOV ctmle-.: V-)11, 1 ;-4 wanvtilq 111, mal 121 2% s, 1U14M."Is 1hr -oin T CC. ~ ,, , , " . "? (~~ t m C 6, Y~ Vitif 11)c--. 4t!?,-r hnt- Kie L IVP rn XTJ - w~ n, !o l I - Ll I w-W 11 "i e )5- I f I K'l ij 4 'g t, q vr I, El" rijitt" t~~v Ink I ZIP W I xt,] f 1.- 12, E .1 fl I 1~t -ro" Ti Yll ! gl.-V "~'! .5 9 M k!,Cl ICCIV C,M., Mki, I W, I ~M M OIS t id,th Ptirri;k-, and NaCl-lc-a uwoliAg ffooj~ -W ivpriata amins in 30 cc. abs. 9 taiTF-1. tOO and a LU ~IV give tN RRINCROO of %44& thfo: f0, ng y1sati, tvtd b.p, or m. P~. 4trn)l. - 2-t b, 176-8111 1A, 94, N -pipard b, --P'fnAMUaJD Of and --40moc* WIA . A Min g I 1'.~ a ith at VH% studd kwacows ---. -/ -V% '- " - au>le wjimiary af-aino, 0-4 alirl to DAU.. ~'acsi,u*ily 4inlo.. tho dhem-4 W1.). thr IOUOwkug RR' R', `,, yizLd. wcoej b p, pivm.)- NI, pt, go, j-1,4*, INS,; By, r't. R-q. H, W) ~~ 30*: Me, K-.Ch . . ~X. 1'11,'L-il~,~, 79, b~ i:M--4C1'. R - fl.). to, 2le". ~t Addi,g'X~.bf A. En 'M4 portkwm w UtOll of PtOll Iztfr - I gi~M %M, WeOti(), t- - 14 to -~O~ " rtop. Addhil 0,A -x~e n iw~Anl~mi %nd 41% PKINO. n A&-w , ~i- tNO v, ','.'-A:' h 87- Ml,' Q'Ims 031 F ~~S "i V. ~l vtwl ponkills t" 0 ~ M;~'f mr. e~"' I )'~' f- Ai' -ing P~ I'V(h (R. '11, V"d. ~.d M, V MA~ ("ff.p. S~t. TP, 'X Isolation of Lho alablel CDWp Oxes of tho me OMPIR (w Mu. plex) 8.7" T G 0 YT rAj Art,%,, 6' J. 933A ill 4k TfFv Y U k)w pointa and spteirk _Oat -OTris 86 lImp-smdea and iuvestAgrilw of dimtqj And J Xua.:1 (Unoirdwhm Me, Fl, FX,,d Pt to yi.-[Al Dr vila tan TIM bw f., %,m with Bxf". 8tp ~ 168 2,) was cWted In Ag app of r~,Yll, D,4) wAs added, t-be wtraj,~ wwclEd r, dil,:d MT rbw DF lh-v d6ti:we being ;,nll It"ve III I", lli~ ~!.x r~distd. A Y'-td wd~, ol~lAlstve- t 'WF MOT NOV 7+f; C-A Iv PIZ i R 4! Dam UK oh3y "m A ".1 Distrt 4VcAM6/4Z3d/4Vc(J) A41.' A study of the elect,'ophIlic 114111,111W toluene by deuterium fluoride and boron fllfluoride3or- I-MY %X -GW-7-K CY 11 a v I A t b, G_y 0 1 A 11. J, IN' udom tsrv Ahafitnia mmiai Tudomilmy6k ~,,,,ag F 0S , .4 KMeminyei. Vol. 9, 1957, No. 1, pp. 3"2 In the courfle of the studies on electrophilic aromatic deuterization the reaction with denterium flufoside was lumt4atcd In the presence of boron trifluodde. A almVe, new latmatory procedure has been developed for he Preparation of deutatim fluorld* through the deuterol. ds of organic add fluorides such as benzoyl fluoride C lear deiderltation, exim-_rIntents, have been made substituting toluene. A aWdy of the Intertutdiary com. Ilem of the electrophilic aromatic substitutions revealed hat cornplexes of methylbentenes with hydrogen fluoride and boron triffluorMe consW in (ad of protonsted met h I bemcnes of the oidum Ionic x4tt (or a compl~m. C-1, Ci Ogg"" :1,95 -~-CO 0 ~,p e0 0 "Bg Cog 16 C) V 190 S~ ~lc e, O-C f~ soi ,is~99J Due Al 0 ue INC, C) CNS 0 0 0 Ove 13 1,91P C;Q, 0: (Al INV. "a V. r,0 0, u 0 ~Tvs~,o es~ e 0 JO lro~ON-' ~P~ %;,, ~'V, ~, '0 ,us 0'- 06:11. &N, epo kx'p- ,~ -re j\j, r,v- , Ov S HUNTGARY organic Chemistry. General and Theoretical G Problems in Organic Chemistry. J"IbB Jour :Ref. Zhur. - Khimlya, No. 15, 1958, No. 50193 Piuthor :olah, Gyorgy Inst :P_ - Title :A Study of an Intermediate Complex, Between an Aromatic Nucleus and a Cation, Which Takes Part In a Reaction of Electrophylic Substitution of an Aromatic Ring. Orig Pub :Magyar tud. akad. Kam. tud. oszt. kozl.., 1957, 9) Tr2, 113-131. Abs :Upon low temperature interaction of a.~otnatlc compounds of a general formula ArH with RF and BF3 colored and stable complexes (C) of a gen- eral composition A3il a RF - BF3 are formol. They are characterized by sharp melting points Card 1/10 HuNG.~,jy organic Chemistry. General and Theoretical G Problems in or6anic Chemistry. Aba Jour Ref. Zhur. - Xhimlya, No. 15, 1958s No. 50193 and a comparatively good electrical conductivity and are e complexes (c--)-C) of structure (I-XVIII). The latter subetancon when reacted with one atom of C (sp-hybrld) and with an elec- tronic configuration of a pentadiene cation lead to Intermediate C, formed during the electro- phylic substitution of an aromatic nucleus, This is caused by the interaction of an aroma- tic ring with the impinging cation. Structure I Is substantiated by Its formation due to an interaction of 3 (or 67)-fluorri-l-methyl cy- clohexadiene-1,4 (XV111) with BF3- UPOn a careful thermal decompos:1tion the cumplex is obtained with good yields, corresponding to mono R substitutes. The products (which consist in Card 2/10 HUNGARY or,3anic Chemistry. General and Theoretical G Problems In Organic Chemistry. Abs Jour Ref. Zhur. - Khimlya, no. 15, 1958, 110. 50193 the case when C Is obtained from toluene, of a mixture of orto and para isomers) contain small quantities of di-R derivatives. A yield of a 50% corresponding to mono-deutero derivatives Is obtained from V-V111. The mere fact of isola- tion of the complexes and their properties in- dicate that intermediate C which determine the speed of reaction of electropbylic substitution in an aromatic nucleus are not -7,--compleyea but V of I-XVII type. R4 \_ R:~i BF4 R '~3 R2 C ard Vlo HtWGARY Organic Chemistry. General and Theoretical ProblemB in Organic Chemiatry. Abs Jour Ref. Zhur. - Kh1miya, No. 15., 1958p NO. 50193 1. R = R2 (or R II. R = R2 III. R = R2 IV. R = H, V. R = D., (or R VI. R = D, = R3 = R4 H and RI z CH3 Ri = R2 R4 = H and R3 = CH3) = R4 = 11~ RI R3 = CH3 = H, R1 R3 R4 = CH3 Rl = R2 R3 = R4 = C113 Ro = R3 R4 = H Rl = M-13 Dp R2 R3 = R4 H, R3 = CH3) R2 = R4 H, Rl R3 = CH3 Card 4/10 HUN,-,ARY- Organic ChemictrY. General and Theoretical problems in organic Chemistry. Abs Jour Ref. zhur. - Khimiya, No. 15, 1958, No. 50193 VII. R D R2 H R1 = R3 = R4 = mUH3 VIII. R D Rl R2 = R3 = R4 = D IX. R C2H5, R2 .93 R4 H Rl CH3 (Or R = C2H5, Rl R2 R4 H, CH7) X. R = 02H "! 51 Rr R4 Hp R1 = R3 -H3 v Xl. R = C2H5, R2 11, RL = R3 = R4 Cji3 XII. R = CHO, R2 R3 R4 H, Rl CH3 (or R = CHO) RI R2 RIr H, R3 = CH3) Card 5/10 HUNGARy / organic Chemletry. GDneral and Theoretiaal G Problem In Organic ChemlotrY. Abo Jour Ref. zhur. - KhimiYa~ 110- 15., 1958) NO. 50193 X111. R CHO, R2 XIV. R CHO~ R2 xv. R CHO; RI XVI- R C2H5M (or R = C2H5'"UOP XVII. R = N02, Rl R4 = H, Rl R3 CH3 11, Rl = R3 R4 CH3 R2 = R3 = R4 CH 3 R2 = R3 = R4 = H~ Rl = CH3 Rl=R2=R4 =H. H3= Olt) = R2 = R4 = H, R3 = OF3 Card 6110 HUNGARY / organic Chemistry. General and Theoretical G Problems in Organic Chemistry. AbB Jour Ref. Zhur. - Rhimiya, No. 15, 1958, No. _50193 Below are listed in the order chc%,,m, meltliir, points in OC and electroconductivity mhos (ohm-1 cm-1) of the molten complexes, measured at the melting temperature - 1. -65, 0.8 IX. -80, 0.2 XIII. -52, 0.5 11. -55$ 2.0 X. -75, 0.1 XIV. -16, 0.7 Ill. -15, 1.6 XI. -15, 0.2 XV. -10, 0.7 IV. -10, 0.6 X11. -70, 0.3 XVI. -2, 0.2 XVII. -50, - Properties of deutero complexes V-VIII are prac- tically the same as the correBDonding properties of I-IV. A general method for preparation of complexes I-XVI consists of passinZ- BF3 through Card 7/10 HUjjGAR.Y / organic Chemistry. General and Theoretical G Problems In organic Chemistry. ;,ba Jour Ref. Zhur.- Khlmlya, No. 15, 1958, ~No- 50193 a solution of RF in ArH while keeping the temperature between -250 and -800. Upoii '.1lie addition to C2H F BF of an equimolar amount of toluene at 100: IR is obtained. By anal- ogy XII is prepared by interaction of tHC-07 + BF4 - (see Ref. Zhur. Rhim. 1957, 77160) e10.1 x 10-2 mhos-1) vith toluene. By adding, (at -800) 0.1 mole of N02F to 0.1 mole Of CF3C6H5 I then by reacting the mixture with 0.2 grams of BF3 at - 1200, and subsequently by mixing and viarm- Ing to -1000, XVII Is obtained . CHOU" BF4 - does not react with CF306H50ven at + 1000. To 1 1 of liquid DH3 at -800 are added consecutive- ly, 46 g Na, mixture of 92 A toluene with 64 g CH30H, 20 g '"if30H~ 18.5 g Na and 36 g CH30H. Card 8/10 HUNGkRY / organic Chemistry. General and Theoretical G Problem in organic Chemistry. Abn Jour Ref - Zhur. - Mhlmlya, No. 15, 1958, No. 50193 This mixture is then stirred for 2 hourn, and kept for about 12 hours. Subsequently NH3 10 driven off by vaporization and the mixture Is decomposed by water. The yield of methyl ey- clohexadiene (XIX) is 52.5j'o. Its b.p. = ]U4.5 _1150. into a solution of 19.29 of XIX in 200 ml Of CC14 are added 37.4 g of N-bromo succini- mide (1 hour.. mixing, 100 C). StIrrInS is con- tinued for 4 hours, and the mixture is kc~A for about 12 hours at 00. The Yield of 3 (or 6?) -bromo-l-meth,vl cyclohexadiene-1,4 fXX) Is 55.2%. Its 00D w 1.5676, and Its decomposition temperature = 400/0.01 mm. Into a colution of 17.3 g of XX in 20 ml Of CH30 is added, ubon Card 9/10 Iiij.n&~Ry / organic Chemistry. General and Theoretical G Problems in OrGanic Chemlotry. Abs Jour Ref. Zhur. - LllmiYa, NO. 15~ 19582 No- 50193 ctirring, a solution of 14 g ASF in 50 ml CH3CN. Stirring is continued for 6 hours, the solution Is a3ed for 12 hours, then it Is fil- tered, vaporized, washed with iced water and finally the remnants of the solvent are driven off (0-05 mm for 12 hrs.). The yield of XVIII Is 46.6%. its n2OD = 1.4975. 5.5 9 of XV111 Is saturated with BF3 at -500 - -650. The measured ma6nitude oT electroconductivity of the reacted mass (-650) is 1 x 10-2 mhos. Upon thermal decomposition the yield of toluene is 24%. C ard 10/10 pIr Qj tit, "QWWt - p Ftirrill contltw 14'x ~cf 0.82 L tab) 'be IV4- amim-11PI W.Move I I Vw .. 'at 4* "i Old S."M11PEt'g '~o fT$'j'j"jf od ja 0'~o Wa* fm,?7V,4. in CS g, t;jzoH in o'- cow "a -g, -i"In m( the ox-lire L' 25 7-f. c- g, and ole, rcbxu~m T"-shIVI ro in ;M;I~t f0ming pre, .1-1. fR U~gj R' rtd A rpa, ~*m gi .4, 4,42t (4.)1 kz--'q- ";q 7D ~-'A-Mecwgp" Fj- B'77j ' jab~-4'1 A. &I. a thv newly 1-1kiry vi ortr 20D ;52" ~ 9 tar, 5 ~4 I a 4e, I', V vxjmk~iA to 0.1 m'-- NW, 400 F by "In of 1~-l mrhe hF? *t - 126'. On wvm~ -l~ , WE te 100 ~ I MAIZ l1r. *" v~ 114 yot" vm -M, *16s a NA tov"d, mi 0* a valvan wm It ve A )llsb T"i of Az ansum d-rwtwv sm tiated Pw uw M., 7fti ut the -4b 'MG* AV wmm o-~ x2mi, 4fg 0, was:* tit ~,' -,- q% -I-1k 441-MAX 71 14MG:X-Cf/Physical Chenistry. Radicchenistry. Isotopes. n-7 Abs Jour: Ref Zhur-Yhim., No 13, 1958, 42474. ;,uthor nlah Gyorgy, Pavlath ;,'%Itiln, Kuhn Istvan, Mali Gycrane, Nobzko Laszlo. Inst Title Study of Rlectrophiuc reutorization of Toluene with Deuterium Fluoride arA Poron TrIfluorlep. IriC Pub: V;agyar tud. akad. Ken. tud. oszt. kczl., 1957, 9, No 1, 301-42. Abstract: No abstract. cards.:. 1/1 13 AR~M%:ovm-, Ii vi-!~., ., A, F, . ol-,il, 1. of t~~e int.'ridtict'nn o4$' p.,rv.,ou3ly mp _1t;), th- .ir , r, I- Po"!Ilain cm 41, 4 1 3 propel'tlo.'3. P'11 A si 7ohn %jr 9 no-2:341-348 jl-,~) 164.k L QLAH, Imre,; SZABO, Gyorgv. Methods to 3measure sensitivity of the cornea. Stmeozet 92 mo.2: 93-96 June 55. 1. A Budapeati Orvoetudomanyi Jastem Lsz. SzoaklinikajamA Jigazgato: Radnot Magda egystemi tanar, az oryostudoatnyok doktora) koslameiWa. (CCnU, physiol. sensitivity, new measuring Instrument (Em)) (OMPAIROLOGY, apparo & instrumentis instrument for measuring corneal sensitivity (11un)) OLAH, Inre. Principles and clinical application of also trore 'tinogmphy. Ssamesset 9-7 no.4:276-283 Deo 55- 1. A BudapeBii O"ostudommWI 3E7atem 1. as. Szemklinikajanikk ,Jigazgsto: Rad:uoit Magda egyatemi tame, , as oryostuclomanyok dDktora) koslemenye. (RITINA, physiol. electroretinography, technic A olln. value. review (Hun)) OLAH, lare Changes In corneal sensitivity In tracbDMA. Slezessat 93 no-2: 79-82 June 56. 1. A Budapesti Oryostudomamyl 7gyatem 1. as. Ssemklinikajanak (Igglg8tO: RadnOt, NSdga bg3retBMI tanar, as orvo9tuaDman7ok doktora) kozlememye. (TRACHOMA, *pbyBiol. changes In cornnal sensitivity (Ban)) (CORNMA, pbysiol. sensitivity, cbangeD in trachoma (Hun)) M 1AH kDNGT, )L ;..0 , 1. The affect of light on the number of eo3inophille blood cells. Acta mod. hung. 11 no.3:393-393 1938. 1. 1. Aupenklinik der Medi2inischen UniTersitnt, Didnpest. (30S321OPH11 COM eoninopanin Induction by prolonged exposure of eyes to light in human voluntearn (Ger)) (LIGRT, eff. prolonged exposure of eyes to light inducing eosinopenin in human volunteers (Gar)) SOLT12 Ferenc; PETER, Agnee;.--OLAH,-I=aj- SIMONTI, Guasta-vj ISKUM, FAklvs; REV, Juditj HERMANN, Robert Effect of rodium nitrate on the cerebral circulation, central retinal arterial proBsure and cerebrospinal fluid premBure. Kieerletes orvoBtud. 3.3 no.3:305-310 Ja 161. :1. BudapeBti Orvostudomanyl Egyatem 1. oz. Belklinikaja.en Numv- logUi klinikaja. (NITRATES pbarmacol) (BRAIN blood supply) (RETINA blood supply) (CEREBROSPIKAL 77-UID pharmatol) I OLAHY I!nre, dr., FMO, Egon, dr. Correlation betvean beadao-he and hypotenslon of -the central arte:17 of the retina, Om, bstil. 202 no.27-1256-1258 2 Je 361. 1. Budapes-ti Orvostudomanyi Zgyetem, Neurologial Klinika. (FMADACH2 atiol) (RETINA blood suPP3,v) SOLTI, F.j MIER,, A..,, OLAII., I.j ISWI~ M.3 REVI J.3 )IMIjtAMJ3 R.; Z. Effect of nicotine on cerebral blood circulation and venouv pre:;2ure. Xioer2. orvostud. 14 no.3s269-272 Je 162. 1. Budapesti Orvostudomanyl Egyetem 1. sz. Belklinikaja es Ideftlinikaja. (BRAIN blood supply) (311COTIM- pharrmcol) OLAH, I=e,, c1r.; IXBORZY, Gyorgy, dr. A mw mothod for -.1he diagnosis olf tlrombc3is of' he internal carotid arterY. IdmoogY. Ozer-le 15 no.C,:175-182 Jo i62. 1. Budapestl Drvostuda=yi Egyutem Neurologial Mnikajanak (Igazgato: Horanyl Bela dr. egyetami tanar) kozlomenys. ITIMOMMSIS diaE) Cvuommy) OAR(rm ARTEMES dia) (CEUBRAL SIMOLISH AND TUE1.01-IBOSIS diag) SOLTI, Y.; FEM, A.; CLAN, I.; ISMI, M.; REV, J.; HMWPN, R.; The acute effect of nicotine on cerebral blood flow and cerebral venous pressure. Cor vasa 5 no-3:197-202 163. 1. Firat ~%dlcal Clinic and Neurological Clinic of the Uni- versity Hedical School, Budapestt~ (CEREE-BIROVASCUIAP CIRCULATION) (RKRIAL VESSELS) (BLOOD PRESSURE) (BLOOD FLCW VELCCITY) (NICOMP.) Oudill Lmri~; Jano3; Gizelln Changeo in syaternic and retinal hy;,ertensicn in patientp lnfluerc~:d by hypotensive agents. Kiserl, onrcotuj. 16 no-4:4301-443 Al, 16/.. 1. f).-MSt,Udu*r:unyl Neurologial Klinflut.ln eo Rol~f~Ct K.,iroly k-rt.-I korha-, I Polryogyaqzatl Cl.,3zt.alya- ROJILICH, Pal, TOROK, Laszlo, OLAH, Imra; Medical University of Budapest, Institutv of Histolory and F,-nT-r-Y-STv-2Y--TBudapesti Orvostudomanyl Enretem, Szovet- es Fejlodestani Intezet). ORibo3one Helices.0 Budapest, A Yar;Mr TudomanXos 0adpnin Diolorl-111 Tudomanyok Oaztalyarsak X'o%lrMPnY41I' Vol V1110 No 20 1965, pages 179-166. Abstract: Helical structure was observed earlier by the authors on the ergastoplasm of pigment cells In mollusk eyes. In the pre-sent, morpholorical study, pictures of the ryoblast cells of 5 day-old chick embryos are pre- sented in which the helical structures are clearly visib)e. Fixation was achieved with osmium and later with a combination of glutaric aldebyde and osmium. The dimensions of the belix are; width 450-600 R, thickness of the line forming the helix 160 R, distance between threads 250--500 R. Helices with more than 10-20 threads were not found. if we assume that the helix Is produced by polymerization of the ribosomes, about 150 of then may be present in the longest helix found. When the presence of helical ribosome structures is considered in different cell types, they are found mainly in differentiating cells wherr free ribosomes, not bound to membrane, are present. It seems that helical structures are needed not for the syn- thesis of proteins to be secreted but for the formation of the own. pre- sumably filamentar, proteins of the cell. Detailed studies are needed to con- 1/1 firm this hypothesis. All 12 references are Western. 3 OLAH~ 19tvan 14 operation of condenner loudappalkerse n0.1112 of covvr N 164. (,!. ~ ;1, 1. '. 1 1) ~: T! - .11 - . If : 'Q ;. ft f, ~' " t.yj 6- 1 ? ; Y - i ! ; I - I - - i : '-;~ j ~ 1; 9 *~ *, . ffrZ'~ i C. T.1! :~; r~ ~j ;Irl 2 11, f : - , . ',' : - -. ', '- ,",r ) T I ,_ , I 1~ !,. CLAP, Istvan The AR 612 type "Facairtan radio rBceiver. Pt.2. Radiotechnika 14 no.8j299-302 Ag Q4. 4, , Ito IW' pt -90*4 ctllo ow ~ha%lf. fow cir-t4. CLAH, J. Mobile laboratory Of 30il machanits. p. 243. HIMYEPITESTUDOMANY1 S77AT . (Kozlekede3- as KozIekedesepitestud=an7i Eg7vsulet) Budapest,, Hungary, Vol. 9, no, 5, May 1959. Monthly liat of Bast Rampean Accessions (EEAI), IC, Vol. 8, No. 8, August 1959. Uncla. HMULIM, Bela, dr.; CLAH Jano dr. .. .9 Data on the atiopathogenesis of angina pectorio and zymasi-dial irLfarct. Orv. hetil. 104 no.1:15-18 6 Ja 163. 1. Gyula Megyei Korhaz, 1. Beloaztaly. (ANGINA PECTORIS) ' (MYOCMIAL INFARCT) (STRESS) (F.11GOT ALKAMIDS, HYDROGENATED) (ACETYLCHOLINE) (IMOSTIGMINE) - A, 111 '. .; Oll .."i 11, 1 ,:- -~.r.ri !!~' i-',, "'I 1"10g;' it. Relationshin bi-tweeel an~7ina p~ctoJ3 an,4 -u-r-naarv I- . . -1 .1 1 ~ I- ~~ 1.- Or-7. hetJI. 105 no.32:1498-111U) 9 Ag 164. 1. Gyulai lvlegyc-A Korhaz, 1. 5r-]gyogy-asvat es Korlbon~tanj oo-"'.'ily. F gep&~;zm~---nck ~ EASZ TO MY, La9z I Jero. ckl-3velezi ne7--.;c.k y e pi I.- e s t ud 5 7 C, m I D '64~ Ch!,;~f, Ruad mnJ Ru,.lrc~-d PlannAng ',for Burkw) . 2, RcHd anl Pallrcad PIRnninF .1 Entcrprl.-~e, BaNipest (fcr Rasztc:izk;,r at-,,3 Oleah). GYPOTMATI Istvan, dr. (Budapest.. 11., Budafoki ut 8)) CLkH 3 KB31= Nudapest.. XI., Budafoki ut 8) ------- AnalysiB Df the rate entropy production b7 tbermodynamic "oqus:tions of notion." Acta, chimica. Rung 35 no.1:95-105 763. 1. Department for Th7alcal Chemistry., Technical 'University, Budapest, `--OLAH9 ORZ4~KarDlYl (Budapest XI, Sztoczek, u.2) On the theory of the alkaline error of the glass electrode. Perlodica polytechn chem 4 no.2:141-156 160. (EEAI :10.4) L Department for Physical Chemistry, Folytechnical University, Budapest. (Alkalies) (Glass) (Silicates) (Hydrogen) (Electrodes) (ion exchange) OLAH,LaJDB---- .- - Comparing soil -temperatures measured on different Boil typ9m. ores meteor int 'boas tud kat 25:96-101 161 (Publ-162)a KAHAN,, AgDB-t,' OLAH., Miklos Lamallar aclaroplasty in the treatment of retinal detack;ment with poor prognosis, Szemeazet 100 no.43201-212 D 163. 1.-A Szegedi Orvostudomany Egyatem Szemklinikajanak (igazgato: Kukan FBrenc egyetemi tanar) kozlemenys. 4 KARM, jlgont, dr.; BaMM, Gyorgy, dr.; CLAH, Miklos, dr. UOLATIM, lazzlo d.r. On the side effect of chloroquine therapy in rhe=atoid ar- thritis and systemic lupus erytheratosus. Orv. hetil. 105 no.19:883-888 10 rt?64 1. Smagedl Orvostudonanyi Egyatem, SzonAlinika es 1. Belklinika. ~A_ OLk,H., ?a:L, dr.; FAIATKIi, dr., riz lkin~,Iatuoa P13MOlytic p:-Operny of extractc of chic?en-i lnf-ps~,-j with chkken chplorb virus. Psgy nllatrri Inp 19 no..":4P..5'~ F 164. 1. Phylada Stw.e Vw,.cAnc TroAncing ln3tltll*.U- (Ilrect-vri Dr. Jonef MoInair .), Bud-~+v-st. QlAHj P.j PALATU., 2. e---- Haemolysing proport7 of organ-extraots containing tl* vlrumen ,of infectim canine bepatitia and diBtezper. Act& voter RmE .12 no*4%409-,415. 362* 1. State Serum Institute "Yhylaxiall (Diroctor: Ja Mcl-nar)2 Budapeat, MAH, Fal, dr.) PAIATKA, Zoltan, dr.j as &Uatorvostudomanyok kandidaturm Control of the pathogenicity of the virus strains of the fowl post CC pigeons through intraoorebral -vaccination. Magy anatory aap Vrp- 168 162. 1. Phylaxia A.Ilami Oltoanyagetermelo Inteset,, Budapest. Hu.: 3 ARZ -1 OLLH,_ Pal, Dr, IIIAU'ILIKA, Zoltan, Dr, candidate of veterinary medicine; The Phylaxia National Vaccine-Pr",ucing ln!;titute (A Phylaxia Allarni Oltuoanyagtex-nelo Tntezet) (director: YOLNAR, jo-sef, Dr). "The Hezaolyltic Effect of the Pancreas Extract of Norral and 5wine Fever -Infected Pigs." Budapest, ;-a7yar Allatorvosok Lapla, Vol 5, I;o 18, May 63, pp 210-211. Abstract: CAuthors' E'nlglish s=rary nodified] The henolyltic activity of pancreas extracts of pigs decrea~,e,d after infection with viralent swine fever virus or inoculation with. lapinized virus. The pancreas extract showed a hemolytic activity in dilutions less*. than 1/512 in 87 per cent of the infected pigs, but 78 per cent of normal pig ext- racts produced hemolysis even in a higher dilution. The denonstration of the decrease of hemolytic activity serves no diagnostic purpose since it varies greatly with the age of the ani:mal and because it can also be demonstrated using pancreas extracts of pigs infected with Aiujeszky's disease or swine ory-sip-olas. 4 Weztern, 3 Laztern European rafarance3. 13 1 4 .- ,OIAH., Sanaor M~dification of postal standards. Ssabyany kozl 24 no.9:20J. S )62. 1. Xozlekedea- es Po.3taugyi Mlniasteriim 17. ?oztafoovzta3,T., 24aaaaki Yejiesitesi oastaly. i :,All, '-.*il,-.c;s , d . 4. .. f ~ - -.r. Y. I.,- , , I - I . --- j~j ") Is I (!rv. "IfAl] . I it; r" 0; , I -1 1, 1 CIM, Jan; -UJAH,. Zoltan burg Ical Anatomy of the supr^cnr4lal neryms In the dog In ralAtion %v OxperlmentAl donsmilom of tho boarl. Aoshl, chir- )7 mr).4$25L-265 Apr -58. 1. UBtAV UlitOj aMtDIDiS LM V Bratislave, pTedWSta doc. MUDr. X. Xratoohvil, a laboratorium experimentaluej chirurgis SkY, r1aditel akademik X. SiBka. J. C. Ustav uzitej anatomie, Bratislava, SR%inkova 2. (MURT, innery. denerv. in dog, surg. anat. of suprucardlac nervem (Cs)) VACBSX&U, A.; OIAH, 2, 3xp er Imental 2 clerot oxy with a f Up. Cas. of Z. 15 no. 2:196-201 -hm a 5 9. 1. Ocma klimika UK 7 Bm',,islare, produosta prof. dr. A. Gala. (R3TIRL1 1EMOMONT, surs. exper. sclerotoW with flap In dogs. (Cz)) MISOVA,V.; 07AH,Z. Cataracta darmatogenes. 'Genk. oftb. 16 no.6:397-4oo s $M" 1. Ocna klinika Ul -7 lratisla-ve, prednosta prof. dr. A. Gals. (CATAMGT compl. ) (SUN dis. ) C ZZIC H 0 S L OVAK i A FulIN J. , 0 P _2L&2YA,_,L1;._1nstitute of Experimental Hygiene, ilovak Academy of Sciences (Ustav Experimentalnej flygieny SAV), Bratis- lava. "Dynamic Recording of Volume-Pressure Curves Obtained in Pat Limp,. Under !~'ornnl Cond4ltions and After Inhalation of Surface-Active SubstanCes." Prague, Ceskoslovenska ;siolorrie, Vol 15, Ho 2, Feb 6'p P 75 Abstract: Th(.1 authori describe an az)naratus for continuous recordiz~l-, of th~~ curves obtained with isolrtt~.,-_ rat lungs. Acnin!DLration of tho surface-active aRent the intrapulmonary ?r,~ssure. 3 *.-Jestern references. Subriitt,,,v,' "16 Days of Physiology" at Kosice, 29 Sep, 65. GL,-Iijos, Arpad, fooloado Xmployment of npocialists. Stat szemle 43 no.3-259-278 Mr 165. 1. Central Statistical Orfice, Budapest. CIAM -~Olsaf 00 W--Mmwom"Mooo Yor the developmot of the HunWian zac'hi induatry. Fhi~r .12 zo.W-3 Ag IQ. 1. Xoho- *B Gepiparl MirAszteriva Partbizotteaganak elso titkoara. (~Un, %7 J"t LIS Vol. 10, Oct- ID' -1959. 01. OLAJJ oz. Mor~hologlcal chargeD Lri advarced )-.,Ydrophtha3mOB. CeB4 oftal. 20.r.o.lt27-31 JaIJU. 1. D=a klJmlka l4kara),vt BratialAvej prodroBta: prof.dr. J,Suzlter. OIAJOS, Arpad, fooloado Some more im;ortant labor data on the mWntrIaB and local councils. Stat szemla 41 no-4235Lt-368 AP 163. 1. Xozponti Statio2tikai Hivatal, OLAJOS, Jozaef IAt us vorker3 attain our 6,3sired objecItivas. Hurls 8 no.12:1-3 D 119~. 1. Szaka2ervezatok Ornzagos Tanaesa tarmaleal 03Zt&lya VaZOtOje. CLU,OwsrL 1, T.. 'The epidemiological significince of recurring jaundice. J.hyg. spidem., Prahn 3 no.4:393-404 1959. 1. InBtituts of 3pidemiolW nnd Xicrobiolopj, PrAgue. (EXPATITIZ 113WTICUS apidemiol.) PRM)MI1, Yeliks; BOBROWOLSKA, Ralina; DLAXOWSKI, Tadeass; STAIMM, Regina; NA3WSZEWICZ, Damuta. Vaccination In Poland v1th a 1ITO attenuated -vaccine sgalni3t POUDDY81itil, Med,doswouDmobe 3.2 no.1:1-14 160. 1. 2 7.akladu 2irusologli P-.2-H. (PMIOMMITIS immunol.) (VACCINES) OLAX.CWSKI) Tadausa INS of gama Z20bulin in the prevention -of i-afectious hepatitI3. Przegl. epidem. 24 no.41,431-,439 160. I* Z Zakladu Epidemiologii F.Z.H. Kierowniki prof. dr J.Kostrzewski. (NUATITJS IN?LCTIOUS prey & control) (GAMA GLOBULIN ther) OUKOWSKI, TRdeusz I Some aspects of radio-epidemiology. POBtepy hig. mod. dosw. 16 =.2: .173-210 3L2. 1. Z Zak3.ndu Ochrony Zdrowia Instytu-tu Badan Jadrowych w Varnnwie, Kierownik, prof. dr B. Kowalski. (RADIATION INJUR7) (RADIATIONS)