SCIENTIFIC ABSTRACT PALY*GA, G. F. - PALYURA, I. P.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001238910020-5
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: June 15, 2000
• Sequence Number: 20
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

AOCZSS:ON N,-I; A74042722 S/XX/63/L I
000/000/0510/0514
YarmonerK0, S. ?.: Kurlyandakaya. E. B.; Avrunina. G. A.; Gaydova, Ye.S.;
Govorun, R. D. ; Orlyanskaya, R. L. ; ?aLly*ga, G. F. ; Pononareva, V. L. ; Fedorova,
V. ~'. ; S?.zaAova, N. L.
TI-LE: Reactions to radiation an chemical protection of animals subjected to
-n c -1
'recta or high-energy protorj
SG~;aO~ -. Konferentniyr. po aviata4ozinoy i 'Aosmicneakoy meditsine, Ic)63.
Aviatalonnaya i cocmlche"kay. ..Ztainu (Aviation and space medicine); materialy*
konferentoii. Moacow, 1963, 510-514
T
~GKC TAGS. corpuscular radiation, high energy proton. synchrocyclotrou, gamn,
ray, radiation effect. radioprotective agent, RBE
ABS~NACT: Experiments were performed to determino the immediate and the delayed
effecta of high-energy protons and their RBZ on animal organiGma. lUgh-enera
protons of 660 Hev were generatod on a syncrocyclotron. Comparative taste using
ga=a rays from a Co6O a6urce were used in establishing the RBE. Nonpure strain
mice and rats were u&ed, in addition to mice of the BALB axA C-57BI etrai".
Cord

ACCESSION NR: AT4042722
All materials were subjected to statistical analysis. in comparative experimcnte
performed on rats subJected to a dose of 500 rad, tne dej;ree of injury to nomo-
poictic organs by protons was considerably loan than injury caused by gamna
radiation. The depression of Lezopoicai6 In the bone narrow and the spleens of
animals irradiated by protons was less profound and lcG5 prolonged. and regenera-
tive processes
began earlier than in ir,4urie3 prouuced by produced by gamna rays.
Tnis difference of effect was particularly clear in the dynamics of the peripheral
blood. After ex-posuro to gzanma irrariation, a profound and prolonged anemia
developed, accompanied by a 'losi, .' -,-% of the erythrocytes and 51% of the nomo-
globin. An equivalent ease o: n; * -... caused only inaii;nificant lowering or there
Indices. Similar effects were ou.-rved in the white blood corpuscleo, particularly
in respect -.a neutropnllc&. The rc&"Ita obtained confirm that the condition of
peripheral blood doer. not reflect the true depth or radiation damage to hemopoiesia.
In exper-1
I iments with white mice, a study was made of early destructive changes
in the brain marrow, the dynamics of mitotic activity, and the kinetics or coil&
with chromosomal injuries. Exposure to protons induced typical radiation do-
go&erat-zon of calls of the bone marrow. a slowing down of mitotic activity, and
izi;.rios to the chromosomes. A atrong'linear relationahip of injury-to-do" w&z
Card 2/5

F
o~oc:-" in a_ tr.rec inaicer -.t'Ir. tne 25C,--', r. ra..r,-. ixpo:- re tr
P,-OnOL.-.C"Q ndicating t~.at
coz-cza of pror.~Cec--
...c of protono ~s eq.~~valent to 3-5--G.7. ?reliminary of radio-
protec-'~ve aFc..-'3 M2.% 6-,crcapLovtry!aninc),
a-l~ P the rLmzc.- a.' aegeneratinj-. and
cc-,s 4n L`c lbore marrow a , opor'.ion to L,,.e effect of tno ,nalcatcG drugs
on s6rvival. Tne roat effect!V, appeared to be a combination a,' FIL-A and 5-MOT.
w,,osc -"" assured tne rurv`val a-' 5U4 a,' tne nice when irradiated by doceG of 1900
rad. .tionatcd, tAe prot..tive effect of the drurG in re-
-f irradiation
duccd sharply. or it disappears alto~atrcr. in experiments on male mice of the
BALB strain subjected to doses of 500 and 700 rad, reversible chanf;es were obrerv-_
ad in the -e42;ht of teaticles. Tre chanZa a,' we1z;rt and its rulosequent recovery
was due to the dcath and the subsequent rei;oneration of germ calls. Protons have
a --ypica.1 sterilizini; affect on tne 1;enltalia, but their RIIES. in comparison
wzth ga==a rays, lies between 0.6 and 0.7. -he use of antiradiation drugs
did not prevent the sterilizing action a,' protons, but it caused a somewhat smaller
loss of wei&ht of the tersticles and produced a shorter period of sterility. White
male mice which had beer. protected by AE:r, FXA, 5-MOT, and cystamine from the
k effects of proton doses of 1300-1600 rad recgvered their generative functions
i Card -3/5

ACCE&SION NR: AT4042722
almost completely four to seven mortha after irrndiation. 'he development of
the first generation or 290 mice ootainca by crossing the protected and irradiated
males with Intact ferales took place without visible somatic in,jurJes. The
relative effectiveness of protons and gamma rays 'in causing somatic mutations
*was studied on livers of white rats who ere suo"ected to doses or 150 rad. Re-
gcnera,~41or, of the liver was induced by removing the large left and the front
right lobes of the liver. The operation was performed 24 hours after irradiation.
The animals were killed 30 h-~urs after the operation, i. e.. during the first wave
of the increase of mitotic activity. Control aximalis hid 6.% of aberrant cells,
while after irradiation by protons and i;anma rays, the number of aberrant cells
was 20% axid 2'1'~, respectively. This indicates that the RBE or protons in respect
to somatic miutatlons is around 0.7. New data were obtained on the blastomol;cnic
effect of protons. Out of 85 irradiated rats, tumors were found in 39. Twenty-
:ive of them had multiple tumors in various locations. in experiments on non-
;Y~re strain white rice, 'it was possible to show that antiradiation drugs, whi-e
ir.creasinZ thL- --*.io resistance of the animals, do not prevent subsequent develop-
ment of now Growth. Out of 65 irradiated mice who died at various periods
after exposure to protons in doses from 1300 to 1500 rad (after having previously
receivou artiradlatior. ;~Cotectioa), fourteen had I*ucosls and four had sarcona.
Card 4/.5

C C _7 S S3 ,., N 3 2 5 : 2 3 S/024l/64/0D9/)03/3066/337L
Yarmona--ko, S. ?.; Paly*ga, G. F
or machanism of antiradiation agents
i.-.g :hc --' r a p ;)l z: i o z, (:I ro ze c t i ve a cr on o f re ct a I I y admi n i s z e rad
a r a-, io,-.:i
S 37Z C ~'.c dz s i -. sk a y a r ao I oi y avn o . 3 . 19 6 4 , 6 6 - 7 0
-,,,GS anti radiatio.-. t, Arcamine, 5-methoxytryptamine,
'A C7 o z o x; c p :- o t .2 zv e e-',a c : o f me r c5 -
ry;~ z L m, nc we -IC e xe r i T-, e a " s v
male mice to Y-.'-rac~.ation
f
GUI*3-7-80,~ apparatus with ra,~ 2-.1 rad/min. T he a:, a i o
arentG were introduced inz rape ly , oral:y, or
33 min before irradiation- 7he toxic !ct pro(--,;cc,~
adminis t rati oR of all' three ?reparaLIO.- was lower
Coto I / 2

.- "..' :: -.,. : :' ? 5 3.
r
0 r 0 -" C a 1 a r (150 mplkv') p r c) d ~~ c e
;7, Z: %2 C '
I Ve 0 C C Ij e 0
(I -a 'I ly, inLranerizonez.
7. 7. 7. -1 r J) C C C: '71 7-~ a r C '-C; v C e a a a r, n i s -
-ect, rect
r a i a r c c -a s i 7.;- e - c o y wz- e n larger doses
0 C Z: a .4 M' n s -, r a t i 0 ZI o f 5 - -.,e 0 x V -
C: U
e a ra C' r v c t I VC e ffect on z ~ t C t e s
U c s ~,L 66 . 7' survival a dose
01 3 3 e c t a I a i s L a t i on o f me r cam. n e
:7:7, " -- I I
s u va 3~)' mg/kg mercam
I " , 0.:~ ce n e , a
z e s M ce a d '- a r a-.y radioprotective effect when in-
z: r ') Z; C e C a 1 c p r o -, c! ctive effe c t o f c o mb i n e d i n r r a -p e r i -
taneal a~~-,inistration of mercamine and 5-methoxytryptamine
~151) + 7j mg/kg) resulted in 95/. survival. The same dose intro-
duced rectally resulted in 50~ survival, Orig. arc. has: 3 c a b I e s .
AS S D C : AT 1 ON none
5 1:3 ~' 17 7 Z D 1 a r 6 3 DATE ACQ I 7Ap r64 ENCL: 00
SU~'~ COD--- N' 0 R 7-7 F S 0 V 000 0 TH E R 000
Caro 2/2

Acassics im. AM42216
S/O0W/6k/1W/OW/0WQ/O463
AUTHOR: A. Tarmonankop S. ?.j, Shapiro, 1. He
TITLE: The repair or chromosome Injury in mating liver calls at rats mom
chronic gimmas irradiation
SOMM: An S83R. Vokl&W, v. W. no. 2,, ig&, 46D-463
TOPIC TAGS: chrowsome, chromosome Injuryp radiation Injuryp resting Uver ceU.
chramosam Injury repairp rat liver,, single radiation exposure# prolonged radiation
exposure,, low dose radiation exposures;M& do" radiation exposurep curAlative
radiation effect, adtotic index
AW12AM: Rarlier studies have sbmm that radiation inJuries of chmaosomes causaid
by a single exposure an retained In resting liver cells or adult rate and nice
for m=y months. The present study atteWted to detemim the possible relation
between. the tim during which a certain radiation dose Is absorbed and the repair
proms of Injured chromasomese Tests van conducted In 2 lots of whito rats I me
I" xud do"
grow& readved &.%im at e6 red/min. 9 the other go same dome at
17010L3 to 598920 aid/alm* The latter were Irradiated araml tin sleek except
'Card

ACCESSIM NR: APM*2216
when cells were rmoved for examination. The mitotic index van determined in
controls and the animals of the first lot. Following stimulation of liver cell
division by removing part of the liver the animals were 3acrifIced. The mitotic
4naex, number of damaged chrcmmows and extent of damage were determined. Results
axe figuredo The mitotic index of the second lot did not differ such from con -
trols. The lover the dose,, the lover was the percentage of cells with chromosome
aberrations. This effect Increased with time; after 6 months hardly W difference
from controls was observed. This was apparently due to repair of chromosome
injuries In the resting cells (60% with one injured chromosmel 40% with 2 or
more). On the basis of observations It was calculated that with tim~e the number
of repaired cells tends to reach 100%. This finding is supported by the absence
.of cells with 2 or more acentric f nts and bridges upon longer exposure. The
concepts an the cumadative effects of exposure may thus have to be re-examined.
Such sumary effects may weaken or fail to appear with very low dosess It appears
that the deteminant, factor in tbase tests was the Im does rather then prolonged
e3gposure. It may thus be possible to r*gulAte chrowe irradiation witbout recourse
to observations fma a single irradlatica* OrIg* arts Me: 2 tables wA 2 figures6
ASSOCIMCM s Institut glgiemr* truds, I profsabolevanly Akadamill misdits"makilch
[cord -.-2/3..--

AccEssion xR: APW*2216
nnxa SSSR (Institute of Work and professional Hygiene, Acad. of Medical Sciences
SSSR); Institut norfologIl shivotayfth Ia. A, I. SevorLsovs Akademil am* SSSR
(Lastitute of Animal NorpWIogyp Acede ftlences SMI)
NNW=: 28D~c63
INCL: OD
BUD cow. LS no jaw sov: oo6 OZHU: 007
Cam 3/3

AccEssim NR: Ap4o42216
nn,jilr SSSR (Institute of Work OAA professional Hygicne,, Aced. of Medical Sciences
SSSR),* Institut morfologil shivatayfth In, A. No Severtisova Akadeall nauk WSR
(Institute of Animal NorpbolWO Aced. fiaences SUR)
8WKW=: 2Wec63 ENCL: 00
Ma CMR.* LS No mw sov oo6 r, TO 007
Card 3/3

L- 2415NS6 uff ii)
ACC MR: APSO01317
SOMICE CODE: tit/0249/65/000/009/0044/0052
AUTHOR: Vo A. A.; Tkaphey, A. W. Chekmov. A. S.; Obehiunikova, G.
ytkovich, -A.
G. r.
1J
ORG: Institute of Medical Radisim, ANN SS
AR,-QbA1* (Institut meditsinskoy
radioli;2" AM-SUR)
TITLE: Reaction of the neurosecretory nuclei of the hypothalamus, thyroid, and
adrenal Slands to radiation Injury of the organism
SOURM.. ANN SSSR. VestftZ, no. 9, 1965, 44-52
TOPIC TAGS: ionizing radiation. pathogenesis, endocrinology, polonium, radiation
~sickness, radioisotope
ABSTRACT- Study.of the neurosecretory nuclei In rats exposed to polonium 210 reveal-
ad a three-stage development of changes In the neurone of the paraventricular and
supraoptle nuclei. Immediately after exposure the neurosecretion flowed rapidly
a2mg the axons, after which elimination and synthesis were in a state of relative
ibalance. lUany, Imbibition-of neurosecretion set in, ending in partial destruc-
Wei 617-001.28-07 : [616.831.4+516.441+616.451-008.6-076.916
Card 1/2
... ... - --------

L 14152-66
ACC NX; AP6001317
'tion of the neurons. The adrenals were studied on the same material at different
periods of acute'radiation sickness. Within 24 hours of exposure the glands increas-
ad in weight almost 11/2 time. This increase as well as the histological changes
were Indicative of marked hypertrophy of the glands due to intensified production of
hormones. The structural and functional changes observed in the thyroid were more
or less similar to.those in the adrenals. Under normal conditions the peripheral
endocrine glands are elements in a "closed" system--hypothalamus-hypophysis-thyroid-
.--adrenal-hormone--mtabolism in peripheral tissue. Introduction of Po2 0 disrupts
homone metabolism, which gives rise to compensatory intensification of the thyro-
tropic and adrenocorticotrapic functions of the hypophysis, resulting in hyperstim-
ulation of the thyroid and adrenals. The isotope accumulates selectively in the
~neurosecrstory nuclei of the hypothalamus and ultimately destroys them. Orig. art.
bas: 2 figurais, 1 table.
SUB CDDC: 06/ SUBM DATE: OSJun65/ ORIG RM 012/ OTH RM oDo

i
q.

BOROS, It., ; PAIYI, A. , ; KOS, T.. ; P'LJZS' Za.
Selection of food by rats and Its relation to productiou of
conditioned reflexes. Acta phyniol. hung. 7 no.):251-2,")5 1955.
1. IL Klinik fur Innere Redizin der Nedizinischen UDivermitat,
Budapest.
(FOOD,
selection, conditioned reflex in rata)
(RIWLXX. CONDIT101M.
food selection in rats)

BOROS, Eva.; PALYI, Anna.; KOS, Tibor,; PAJZ5. ZBUZB&.
Selection of diets in rats during production of conditioned
reflexes. Kiserletes orvootud. 7 no.2:176-185 Mar 55.
1. Builaposti Orvostudomayi Iffetem II. oz. Balklinikaja.
ONFIR , CONDITIOM,
prod., selection of diets in rats)
(DIETS,
selection in prod. of conditioned reflexes in rats)

HOUR, Imre, Dr.; IAWYI?Sl, Klara, Dr.; PALYI, Anna. Dr.
Administration of oral antidiabetics in liver aiseases. ~rv. netil.
98 no.35:958-960 1 Sept 57.
1. A -~udapesti L)rvogtudomgnyi F4Vetem 1. sz. Belk linicajanak (igazgato:
Huszn.vak Istvan dr. egyet. tanar) kozlemenye.
(DIABBTBS MELLITUS, compl.
liver dis., indic. & contraindic. of carbutamide ther. (Run))
(LIVIR DISWES, compl.
diabetes mellitim. indic. & contraindic. of carbutamide
ther. (Hun))
(ANTIDUBSTICS, ther. use
carbutamide in diabetes mellitus with liver dis.. indic.
& contraindic. (Hun))

i AL', , ' 'BFT,
L-': n-I.;-. , ?.em. I-In-.,,ni'rat "117--
(1950)

PALYI, F. - Vol. 1, no. 6, June 1954. (jaryruvek es
Data an the designing of silagge cutters which fill silos. p. 190.
SO: Yonthly list of East European Acc,.-ssionB, (EFAL), LC, Vol. 4. 11o. 9, Sept. 1955
Uncl.

PEM, Ferenc, dr. (Budapest VIII., Rakoczi ut 27/b); RUSZNAK, Istvan, dr.
(Budapeet III. Norvin O.u.44); fALYI_t_' Wa (Budapest XII, Meredek
u.43); SZABADOS, Ida (Budapest XI., Moric-zls-igmond korter 14)
Investigation of adsorption waves. I. Investigation of the reduction
of anthraquinone-l-sulphonic acid at the dropping mercury electrode.
Acta chimica Hung 24 no.4063-370 6o. (EW 10t4)
1. Department for Applied Chemistr7, Technical University, Budapest.
(Adsorption) (Anthraquinonemlfonic acid)
(Electrodes, Dropping mercury) (Riboflavine)
(Methylene blue) (Polarograph and polarography)
(Diffusion) (Phenazinol)

I ETM, Fereric, RUSZNAK, Istvan-, IMI,Yl, (,yiil,,I; -,ZAB-D,'~, 11 1-1
r. .r *--Ive,3. 1. ~~,X%Mjna~,',rj r,,f - - -
ne-1--iulfonic-acid reduc-.ion -,,. ing P-' en-'-r . ' :,~
kem fol-ioir 66 n( -5:178-101 Yy 160.
1. Budapesti MuszpkA- ',,gyetem Gyakcrlald Kemiai Tanszeke.

hUS2,14AK, Istvan; PETER, Ferenc; kALYI,, Gyula
Polarograph-47 -investigation -f i~~a aminor--7-oben?z,%c- deriva"veE.
Mata kem folv:)ir 66 no. 3.81-84 Mr 160.
l.Budapesti Muszaki Egyetem Gyakorlati Kemial Tanszeke.

PALY1, rlyula; PETER, Ferenc; SZEBERENYI, Istvan
Polarographic investigation of xanthene-type phthalein de-
rivatives.Il. Reduction of quinoid and lacto form of 3,6-Di
(diethylamino)-9-(21-carboxyphonyl)-xanthydrol(rhodamineB).
Magy kem folyoir 67 no.lOt424-427 0 161.
1. Egyesult Veg)rimuvek (for Palyi). 2. Textilipari Kutato Intezet
(for Peter). 3. Petrik Lajos Vegvipari Te-chnikum (for SzebereTlYi).

PETER, Ferenc; PALYI, Gy-ula
Polarographic investigation of xanthene-type phthalein
derivatives. I.Effect of substituents on the reduction oc-
curring on dropping mercury electrodes of phthalains. (To be
contd.) Magy kem folyoir 67 no.10:420-423 0 161.
1. TextiliFarl Kutato Intezet (for Feter) P. Egyesult Vegyimuvek
(for Pa3vi).
1100'r

PETER, Fereno; PALYI,--G~Iula; SZABADOS, Ids
Investigation of adsorptiop waves.II.Investigation of anthra-
quinone-1-5-diBulphonic acid reduction on dropping mercury
electrodes. Magy kem folyoir 67 no.10:428-431 0 161.
1. Textilipari Kutato Intexat (for Peter) 2. Egyesult Vagyimuvek
(for Palyi) 3. Orazagos Kozegeozeegagyi Intezet (for Szabados),

RUSZNAK, istvan; PETER, Ferenc; PALYI, Gyula
Folarographic investigation of some triphenylmethane derivatives.
Magy kem lap 16 no.6:287-289 Je 161.
1. Budapesti Muszaki Egyetem Gyakorlati Kemia Tanszek.

PETER, Ferenc; FALYI, Gyula; SZABkDOS, Ida
Investigation of adsorption waves.111.Reduction of anthraquinone-
1,-8-disulfonic acid on dropping mercury electrodes. Magy kem
folyoir 66 no.6:234-236 Je '62.
1. Textilipari Kutato Intezet, Budapest (for Peter).
2. Egyesult Vegyizavek, Budapest (for Palyi).
3. Orsaagos Kosegeszsegugyi Intezet, Budapest (for Saabados).

PrMR, Ferenc; SZABADOS, Ida; PALYI, Gyula
Investigation of adsorption p~enomens occurring ob dropping
mercury electrode.I.Effect of leuco-anthraquinore sulfurinc
acid-ester derivatives on their reduction occur2ing in the
nitro-benzol-3-sulfo,mi,! acid agent. Magy kem folyotr 68 no.3:
101-105 Mr 162.
1. Textilipari Mutato Intezet, Budapest (for Peter) 2. OrszaRos
Kozegeassegugri Intezet, Budapest (for Szabados) 3. Egyesult
Vegvlmuve~, Bud.speat(for Palyi)

PALYI, Gyula; PE, 7z;17, Feranc
SyntAiesis of polarographically pure diaxanc. Nagy kon lap
I
17 no.8:354-356 Ag 162.
1. Fgyesult Vegyimuvek (for Palyi). 2. Textilipari Kutato
Intezet (for Peter) ,

PALYI, Gyula; PETER, Ferene, dr.
Application of oacillopolarograpf.7 in certain tax-tile -& -1
investigations. Pt. 2. Magy textil 15 no.7-.28-3-28? JI ,~-).
1. Egyesu-It Vegyimvek (for Paly-i). 2. Textilipari K-utato
Intezat (for Peter).

FZTLR, Ferenc, dr.; PALYI, 'J)%,da
Application of oscillopolarograp:.y in certain textile ciienical --'n-
vestivations-Pt.3. Magy toxtil 15 no-10:462-466 0 163.
1. Textilipari Kuta-I-o Intezet, I~Udaptjot (for ,.. Fryesult
VeQ,imuvek, budapest (for Palyi).

P "-' , " - , j-lr,- I-a
St7uc Lure de:,o- or tr.r. 1 ,'~ - , , f,f-
o-rp,aT,.i c cG.-.i c-.L; . P ~. 1. fc :- '71 no. 3: 1- r)-L I
41 - I-
Mr '65-
1. "n-' te. --% 1 '-,orlr-.r, , Tiu- ~; -V, ~. - .~Ili --., '- ~ ",! 11 ,

L 1WA-66 T/1WP(J) Fd4
ACC WR i APbOO85M SOURCE CODEt HU/0003/65/073./00.1/00.1/0005
AUTHORs -Pelyi., 2M-Ess Peter. Ferene
ORGs United Cherdeal Works, tgajmst (Egyasult Vegy1mvek) j Re -search InstitutAP
for Uw Textile Industm Budapest (Textilipari Kutatointezet)
I e
i TIM : Appikications of oscillo-polarograpbV in som text "ies.
Part 6t Relations between the structure of 2-1WdrmW--5:M-pHVmni11de and its
derivatives mad their cocillo-polarographic behavior
SOURCEt Magyar kamilai folvoirat, v. 71, no. 1, 1965* 1.5
TOPIC TAGSt polarograpby, adsorption, electrode, desorption, organic nitrogen
compound
ABSTRACT: [Part 5 of'thii*series was published InoChem. Zvesti:'Vol IS
1964p p 4441 The oacillo-polarographic activity of 2-hydroxy-3-naphthanilids'
and its substituted derivatives.was attributed to the adsorption and de-
sorption of the molecules at the surface of the dropping xwrcury electrode.
The tendency of foriming adsorption layers to caused by the part of the zole-
cules-havLag the structure of salicylic acid antlide. The applications of
Cwd 1/2

L 16534--66
Acc wRi APW5M
i tIhese findings.to the analytical chemistry of Wap4thol-As type dye compo-
ments won discussed. Thq authors thank Nobel Mae winner Prof* Je H!UO-V$&,
Mr. j. Kuta and M. Heyrovsky for valuable coments and advice* Further thanks
is -gl-ve-n-Va Gyorbire for the polar raphic radiometer
and neasurementee OrIg. arr; ~-ws 13-figunso PPJM?
suB coDzz o7 sum DATEt 3DDec63 ORIG RJWS 002 OTH RJWI 006
CZ$
2 2,

CZIEWSLAYVAKIA
PATjjp 0.1 JESM, IL
1. t1hited Cbmical Wo*sp bod"Ost (for PAOI) 1 2. Grow for the
Db* of Fkjmiad Methods In Auslytical Cbmi*Uy, Oexuas AeadwmW of
Sciemmes, Berlin (ter jobving)
PmmVwp SLIleatim of Cusebowlevak Chim4eal Cammmisatia" No 120
See 1965p pp ON-4349
*Depeadmoo of Wo admorption of oramie eampumda at the droppift
mwwA7 electrode es the structme. Part 61 Comparison of admarption,
""wily or malleylamulds md X-&Wdv--y-3-mpbWmIlId* affiviatives*0

L 39565-66 FWP(J)JT DVGD
A-CC-N-R. --Ak0M-j7
D1.
AUTHM: 'Lilyi, qula--Palfx fB-,d;ip-st!; Peter, F-renc 'Doctor;
ORG: UritAd Chemical Work5; Research -,Ap for t~~e Tex" ,.rdustr..,,
TITILE; Application of oscillopolarography in ,-,tne
Pam 6: Correlation between the structure and o,-.cifl-0PoT-arogrfip1Jc ber,*',/:~,r of
2-hydroxy-3-naphthanilide and its derivatives
SOURCE: Academia scienlilrurr, hungAricip. Ac~;i v. no. ', '-f-:',
TOPIC TAGS: polarographic ~maiysii~s,
compound
AKTRA-~-- "irt 11 of ser;es Was pu~!~She,4 In ChoTr-
V,ic accivity of the various derivatives oi Napb-
thol AS (2-liydroxy-3-,-iaphchanilide) was ?ractically identical. The results
of t'~,,esa sztdies i--dicaze t~.zz chis ty;>e of azo-(1ye cow,)orenL -ay be em?-
loyec~ by z''-e samz mechoc, ir7,~spec-,Iva of co-.-->osicion, and chaz -~e osc4lllo-
palarograp C: Ck:Chlique is Z. ble me~-n-. _nv,2:s c ina L in excile C`L:
cr
i -.allure.
:'or ,.,ier
-r. E, arG Dr. X.
for po F, s iI ethese exper:-;ien~:.
a polarograph Radior-e-.,er .axes. L j PF4-1
SUB C3DF: 07 SUBM DATE: ~F13 iiEF: Cx)3 / Cri ~ FFF:
Card

L 41713-66 T - DS
ACC Nks APb03168l SOURCE CODE: HU/0005/65/071/(,-'/0427/0432
AUTHOR: Jehring, Harry; Pa l* Gyula I /
ORG: (Jehring] Work Group for Physical Methods in Analytical Chemistry, German
AcadenW of Sciences, Berlin (Arbeitagruppe fur !Vsikalische Methoden der Ana ischen;
Chemie der Deutschen Akademie der wilssenschaften); LPalyi] Uniteif Che cal Wor
Dwapest (Egyesult Vegyimuvek)
TITIE: Data on the structure of film forming on the surface of the
dropping mercury elect ode Part
SOURCE: Magyar kemiai folyoirat, v. 71, no. lop 1965o 427-432
TOPIC TAGS: adsorption, electrochemistry
ABSTRACT: The tensa~etric curves of a number of substances, specifically
of 4-(14"-methoxy-6"-(hydroxyethyl)amino-triazinyllamino)-4(14"'-ethoxy-
6~"-(hydroxyethyl)auinotriazinyllamino)stilbene-2,2'-disulfonic acid and
4,4'-bisl(4"'-sethoxy-6"-phenoxytriazinyl)aminolatilbene-2,2'-disulfonic
'acid, show characteristic depressions. A study of these depressions indi-
cated that they could be explained by the formation of adsorption layers
on,the surface of the dropping mercury electrode. The forsistion and struc-
ture of this layer was investigated. Orig. art. has: 10 figures. 1JPRS: 33,5401
SUB CODE: 07 SUBM DATE: l0Feb65 ORIG REF: 006 SOV REF: 002
OTH REF: 022
Cwd 1/1

L 41959-65
ACC NP .----',-LU9 SOURCE CODE: HU/OC)05/66/000/001/0029/0030
-.1nOR: Jehring, Harry; Pal.)q, Gyula
-------------
3RG: [Jehring] Research Group for Physical Methods of Analytical Chemistryo DAW
zu Berlint Berlin-Adlershof (~Arbeits~gru fur Prhnysikali5che Methoden der
u~ p
Analyt ~sc qn Chemie der DAW zu Ber in al i United Chemical W6ik&p Budapest
i Y~
(Egyesult Vegyim-u--v--e--k)-
TITLE: -Aq,~ti~on~potential range of 2-hydroxy-3-naphthanilidelderivatives
SOURCE: Magyar kemiai folyoirat, no. 1, 1966, 29-30
TOPIC TAGS: adsorption, desorption, polarographic analysis
~iABSTRACT: During an &.c. osaillopolaro-
~graphic study of 2-hydroXY-3-naphthanilide derivatives a capacitive
!incision was observed at the cathodic branch of the dE/dt - fl(E) curves.
,This incision has been attributed to a dosorption process, and it was
~assumed that the compounds are adsorbed over the potential range betw
;the positive and of the oscillogram and the incision, on the electrod:!r
I
Laurface. In the present work this assumption is confirmed by means of
!the tensametrio curves of the investigated compounds. Orig. art. has: 2 figures.
ZJ-PRSS 34,80,9
SUB CODE: 07 / SUBM DATE.- 311day65 / ORIG REF.- 004 / OTH REFt 002,
Card 1/1 o aL ---

L 47?62-& JAJ
--A" NKs -HU/0005/66/0DQj.QQ/0097 101
6AP60-3468C SOURCE CODES
AUTHORS Palyl, G-yul&,__and Jehring. Harry ~Alyg United Chemical Works, Budapesf(E&
ultveaimi'i-7-ve~JEiM~:ir~g/Work Group for Physical Methods In AnalytIC&I Chemistry
German AcadecW of Sciences in Berlin (Arbaltsgruppe fur Physikallache 16IMen der
.Analytischon Chemie Deutsche Akademle der Wissenschaften zu Berlin) Berlin-Adlershot
93tructure-5;~ndence of the PolarographiefAdsorption of organic Compounds.
11. Investigation of ~he Tensametric Curves of 434'-bi&(tri&z1nyl&mino)*tjl-
bow-2,21-Disulfonic Acid Derivatives"
Budapest, Ksf-ryar Kejniaijolyolr~at, Vol 72, No 3, Mar 66; pp 97-101.
'Abstract [Authors' English abstract]: The tensametric curves of some variously
substituted 4.41-big(triazinylamino)stilbano-2.21-disulfonia acid derivatives
have boon investigated. It was found that at least from -0.10 V to -1.10V
(SCE) the compounds are present on the surface of the dropping mercury
electrode in adserbamd state. Owing to this adsorption, the electrode capacity
Is decreased in this potential range, and then the desorption process at
-1.10 V gives rise to & ton3ametric wave. With some compounds deviations
are observed in the shape of the polarogran indicatinj: that although the
substituents of the basic molecule hr-o no effect on the adsorption ability at~
the mercury drop. they may affect the structure of the adverption layor-0
Orig. art. hass 10 figures -and I tab
, 416-OOZZ
TOPIC TAGS: aderrption, polarograpffishns-LY-0 orprion, organic
sulfur compound
ES 07 1 SUBM ]DATES 10 IP*b 65 / ORIG REFS 005 / OTH Rtyl 004
8,! 2d C 0')
I/

EXCERPTA MEDICA See 16 Vol 3/8 Cardio. D19. AuR 59
2211A. Effect of digitalis on nerveless heart tissue PAI Y1 1. and RA111rLs N 111"t. tit
tfi4;tol. and Embi-vol., Med. Univ . littdapet Art~_~tW._Acad. Set huvvg~ 147)8, (4 1
(71--78) Graphs .1 Illus. I
The effect% of lanatoside% A, B and F (digtlanid') were stit(Ited on explanted cardiac
tubes obtained from ",-hour-old chick embryos. Pulse rate wa-,; depressed only by a
high concentration (10 ;Ag. /ml.) in the culture medium, whereas AN conduction w as
impai red even at lower concen t ra t ion s. A t 10 g. I m 1. and I ;Ag. ! m 1. t he d n ig ret arded
proliferation and increawd cellular degeneration. At 0.01 pg. iml. it appeared to pre-
vent degeneration of the cells. Lu - Ottawa (I[, IS)

-PALYI, I.; GiL-CZI, E.
Evaluation of the effect of chemosherapeutic agents on tissue
cultures. Neoplasms. 8 no.2:195-201 161.
1. Oncopathological Research Institute, Budapest , 'Ungary.
(ANTINEOPLASTIC AGE14TS pharmac.1)

PALY I I Iron, dr.; AFRA, Danes, dr.; CSANDA, Ehdre, dr.
Behavior of glionas In tissue cultures. I. The astrocytom-Clioblastoma
group. Ideggyogy. 99mle 14 no.8:225-237 Ag 161.
1. Budapeati Orrostudomanyi ffgyetem Szovet- as Fejlodestani Inuzete
(Igazgato: Toro I=* dr. akademikus) I az Ora) zagoe Idegaebeezett Tudo-
manyon Intezet (Igazgato: Zoltan Laszlo dr. .
(GLIOMA exper) (ASTROCYTOMA exper)

"6 2/ j 0
0 Hs
2 _-EH
'21,ew I, d 1 6- Of Y I I
i.c. S.-Pply and in pa -L c i i 7-ILC 4. r c s u e
re ay -.ime opera-uion s con'~ro_ led ~,,y -,!~e res 4 stanc,~ f I X i
time delay. ~.he relay -'s c-L3sed uy a ~:ey aided by tl~e
Abstracter's note: Complete ~runolation._7
Card 112

Delayed semicuriducLor ~)I;/ (,ff 0
Card 21,'~,

FALY1, Iren, -- Dr-egTetemi tanarseged (Budapest)
Ir --
The effect of Ionizing rays in tissue cultures. Term tud
kozi 6 no.2-59-62 F 162.

J~-# Jr., A.; PALYI, I.; HFMA-DI, F.; VALXI-NAGY, T.
Search for antagonistic actinomycetae in Hungarian soils.
V. Effects of fermentation liquids in various in vitro tumour
tests. Acta biol. acad. sci. Hunff. 14 no.2:101-109 163.
1. Institute of Pharmacology (Head: T. Valyi-Nagy), Medical
University of Debrecen, Research Institute for Oncopathology
(Head: B. Kellner), Budapest, and Department of Antibiotics
(Head: T. Valyi-Nagy), Research Institute of Experimental
Medicine, Hungarian AcadeEy of Sciences (Director: I. RuBznyak).
(ACTINOMYCETES) (SOIL MICROBIOLOGY)
(STIREPTOMYCES) (CARCINOMA, EHRLICH TUMOR)
(AITTINEOPLASTIC AGENTS)

7A`
cient4fic lns-L--ut, La.,,zio, r/ and Yedical
a:.: :n,.*,-i*,u*,e (,~--'rector: TCK, 1-rre,
es ~-uja;~est.,
Orvos tU4 z)many-i E:-yetem
"The Behaviour of in -issue Cultures."
I XT*j, No 7, July 1963, paves 19
!~jdane5~t, ':-
t ra t~
A ---t. 'Aathors -,ar:..-,n surr-.;iry mo~lif !Pd 6omi-,a rat1,j,-- 1-i ~ie
made or Sanples tikeri (!ur'.r,,, t,.e first arcl secc:-..,, op-ration in four cases
of ~IiO7.a. pati---rAS w-it,- o?-;.io3la5tc;,ia -.~dt-,forme ana one with astro-
cytor.a mali6nw. ra,iation treaLment after sur,!ei-~ while a sf:,conc
patient witl~ astrocy-Loma. maliC,,num was not treated loy irradiation. The ir-
ra,Jiatel tissue cultures showed uvidence of ,4e-7enera-.ion already In the
third wte~. -.he decrease of bllolo,-)-cal activity In irradiated tumor ctll~-
can be considt-rc-!,1 the result of raciiation effect. Durint-, recidive ziur,--ry
there was evi,;crice or a chan;-.e towaird Increa.-I-eu mali-.nancy in the non-lr-
radiate-4 tumo;, tissue. In one of tne cales, the activity of the tumor ti,,-
3ue removed auring the ini-~.Lal showel-4 evidence of malignant astro-
cytom.a, Indicating the malijnart chan,-.e which was actually found in the
-,issue which was removed durIng the second operation. 2 Hungarian, 14
Western references.
1/1

ZOLTAN, Laozdo. dr., JALv' kF -A, D`~';"
T I 'tu:
I he be aa v ' c, r r, ' g - I C,fnil 3 e ra,ive
studies on gi.,Dma3 irraLii;it--i -.,. vivD. sze.-le _'b
nc.
(lgtlzf7ntc:
Zc. itan Las L IT Bud:i pf, I C'i tu"liomanyi i.gyeteip.
e t - a 7~ 1 Torc Imre dr.
J e:'.

PALYI, lren, dr.
Animal tissue culture. Elovilar 7 no.3:.-