SCIENTIFIC ABSTRACT RYSANEK, C. - RYSAVY, F.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001446510001-9
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: September 26, 2002
• Sequence Number: 1
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

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CZECHOSLOVAKIA
RYSANEK, K.: VITEK, V.: SVEHLA, C.: Medical Clinic, Instit-ute.of
Corig. version not iven7
T-ost'g'or-a-M29~rMedical Trainir~g. Prague. 9
"Hydroxylation of Indoleacetic Acid and of Tryptamine In Vitro;
the Action of Monoaminooxidase Inhlbltors.11
Prague, Activitas Nervosa Superior, Vol 8. No 4, Nov 66. pp 373-11,
375
Abstract: The influence of iproniazid and tranylcypromine.ori
hydroxylation of 6-hydroindoleacetic.acid,in vitro was investi--,.
gated. -Liver tissue had 10. t,j;mes as high a hydroxylating
Indole
activity for tryptamine as acetic acid (IAA). Small
Intestine mucosa can hydroxylate.tryptamine to o-hydroxytryp-
tamine, but its 6-hydroxylating potency is only:1/10 that of
the liver. Ipronlazid Inhibited conversion of 6-HT by 161co;
tranyloypromine showed no Inhibitory action. 1 Figure, 1
Table, 3 Wes,tern,.l Czech, 2 Japanese references, Submitted
at the 8th Annual Psychopharmacological Meetirv-c'at Jesanik,
18 - 22 Jan,66. Article is In English

CZECHOSLOVAKIA
RYSANEK, K.: SVEHIA, C.: Institute for Postgraduate Xed1cal Train-,
-TE`g-,'M'd-YdFmT-Cl ini c, Research Institute of Experimental Therapy,
Prague, Kre., rorig. version not given
"Metabolism of Indoleacetic Acid Following Monoaminooxidase,tIn-
hIbItIon."
Prague, ActIvItas Nervosa Sup r1or, Vol 8, No 4, Nov 66, pp
375-376
Abstract: Substances giving kynurenine reactions were found in:
the urine of some people who were subjected to a serotonin.load.
In a follow up experiments on 5 volunteers are described.
When 3 9 of Ia were administered excretion of kynurenine type
substance:3 increased significantly. Chloramphenicalcaused an,-
increase of a much more limited nature. When certain pathways._
of the.IAA metabolism are Inhibited by.MAO Inhibitlon,-other~'
pathways are used. The compositioxi of kynur'enIhe substances
was not determined. No references. Submitted at the 8th Annual
Psychopharmacologloal Meeting at Jesenlk,.18 22-Jan 66.
Article Is In English.

CZECHOSLOVAKIA
1/2
i
m

C ZEC.--.',OS IJOVA;~- LI
RYSAT,=, K., VITIM, V.; I~ediical ClinIc o.--.- Pest-rarllu:~-Iq "'c6ice-I
TftI,:r1uMMu 8',"PrI-Igue; Researcia Institute for
Pra--Ue. /Orig. version not Given-7
T
"The a;:cretion of 6-'Hydroxyla~ted i-Letabolites of I-ndoleacotic Ard
-Poll-owin- Peroral Loadin- with Indoleacetic Acid."
To 66-, pp
Prague, Activi as Nervosa Suporior, Vol 6 No 1, v
378 3130
U4
Abst-ract: Hydroxylation of DkA in the O'tli 7)osition is discussed;
-,ical me.-aing ur! I . --
1 .0
is probai).-y one I
its physiolor, n is cnown, bu Ui.
the detoxication reactions. The 6-hydroxylated com.-ounds of indole.:
affect hhe GNS -,.-,ore than the original coi,,mounds. E~-:creti on of
7
ter a peroral load of 39 of - IAA was s Ludied in 0" la c a 1 tit
6-HIAA a a
ly
jects. excretion of 6-HLUI increased to 26 7?:~ dany fron',
sub
r.- .1 1 1
an original 8.2 mg as a result of the loading. 1 Pi ure 8 ~-Jesu-
c_~
ern, 2 Czech references. Submitted at the 8th Amiual Pr,-jc*---oT)har-
nacoloE.-ical. Mectim- at Jesenik, 18 22 Jan 66. Artl'Cli~., is in Eng-
1 ish .

CZECHOSLOVAKIA
1/1

a
L 29471-66
ACC NA, SOURCE CODE COMOiQ
Amo19979 CZ/0079WOO
Pr ek, Ve
AUTHOR: lZysanokt Ke ague); Vit
ORG: Medical Clinic, Postgraduate M'edical Institute, EKqZue_
TMIR* % * Evaluatio onversion fThis pape
n of the,Sloerdsna tost of serotin c rwas pre-
,sontl ad at the 7th Annual Psychopharmacological Meeting, Jesenik, 20-23 JanuarY 1965 1-1
SOURCEt Activitas nervosa superior, ve 7. no,, 3, 1965, 264
TOPIC TAGS: serotonin, enzyme, biochemistry
a*
ADTINUCT: The test is a valuable indicator of tha.monoamino oxid a irdiibition in
ran if the investigated,subjects havo a rdmiram basic conversion of 50."6, and'if th6'
Variiability of tho convorsion was examanod bofore the test* ~ The excretio.n'of 5-kvdrol'
xyincloloacotic acid rust be chock-ad after moro.than 8 hours after to St An inhibitioz
n ma bo taken as a clear proof of-monoamine oxidase
of conversion larger tha 50p"'
irliibiti=6 fOrig. art. in EnZ.~,cipR-S7
SUB.CODS: o6 SMI DATE i none
Card

29463-66 -------
ACC NR: AP6019986 SOURCE CODE: CZ/0079/65/007/003/0271/0273
AUTHOR: Viek, V.; Rysanek, K.; Voitechovsky, M.
O'aG-.'-Research Institute for Experimental Therapy, Medical School of Postgraduat~_
Medical Institutev Prague; Institute of Human Nutrition, Prague
TITLE: Excretion of tryptophan d catecholamine metabolites after . Za nistration7
jLn dmi
of cycloserine'Ysomers in man ZTh.is paper was presented at the 7th Annual,IPsycho-1
gtr-7
pharmacological Meeting, jesenik, 20-23 january 62/
Activitas nervosa superior, v. 7, no. 3, 19659 271-273
TOPIC TAGS1- tryptophan, biologic metabolism, pharmacology
A---ST?,kCT-. 1-Cycloserine (GS) Is the Isomer that interferes most strongly with
'tryptophan metabolism. CS interference with tryptophan metabolism'is not shown
1.71 the excretion of indo-leacetic acid either in healthy '7 or in sick subjects..
Orig. art. has: 1 figure. Zorig. art. in Eng--7 Z-7PI-1V
S UB CODE. 06/ SUBM DATE:* none/ 0MG- REFt 005 OTH REFs 008/ SOV~REF: 001,1
Card 1/1 fv

C
V. VOT._,~C1TOtr3-cy I.L,
--nd -[JTIc,,, E., Clh_air
1~. - -z of
I i -n-e- - ',-abed -itute for "He Pos'
_e Icil-le L, ni ra) , inst U u
U, r a d u a e iillrairling of _'Physician. L
S (us-, av Dro dosk-olovan~ lek
Research institute -for '2`..-_-oerime-ntal he-any (Vyzkv_mny ustav ex-
Lerimentalni teraDie), __Prag7ze, D-ocen-tt, 0. S-HAIEEL, I-Qu , Dr o-f
Sciences dia7ec-~;or; and institute -fo_r iwt:ritvion Research (,Ust-av
.)r o -,.- .-. I I Dr ol"' Scien-
Pr of iJ.SEK HID
jziaun vyzavy- lidu), PrE4~me,
ces, d:L:,.-ec~.or [_ijiC:"Ii,,ridual wFfliliations can:aot be deteruiinedj.
__sect_ of 2eno" axmaii on the llxcr,~'4orn of 5-1~,,-droWindoiacetic
c-" d and 'etilo.-A-i-4-F-ydro.-.--j-,.qandelic Acid in Nan.
Prague, Caso-)io Le Ceskyeh, Vol CIT, xio 40, 4 Ocu
tober 633,
uthors' 1 1 i s h s u:, LT.
trac' riGdified] A comaparxison. of
Abst Y7
the concentrat-i on of' electroDInoretically divided lipopruteins 2M
ffering I-Prom avitami
(,uinea pigs satva~uted.T,,d Uh vi--amin C and sua,
osis showee, t-hat early stages of 'he C avitwainosis inc-reased.
V
s,-,nificantly the level of x, and.decreased the Ileve! of OC2
liDoDI-oteins. A liver dariage caused by administering., eaz-bontetura-,
ch-loi-ide had a cousiderable effect, on t-he se-rum level of the-:Ii-oo
'02:~Otelrl fractions. in them fi_-st 'u-Yo days of intoxication both the
saturated and z:witan-Lnous gai-nea pigs showed an increase -of the
1/2

C~,,ECHOST,U1.4IT'j I
P~agae, Casoi)is Iel:~--u Cesi-.,r Vol Cli-, i,1040, 4 October 63,
L -L.' ch
pp 1099-1102.
i 'ei
---d O-f"---ac~uions , in d adro-o of the oc~.--ra-ction o -rjoDrot
On tI-Ie seventh day, after CC!,-, admi-nistration, botil- san-.Ln-aued and
showed a conspicuous tendency for normal-
avi -a-Minous r,,,ui-nea pigs
u
'esults:T)roved that the early stage of the,C avitaminosis
iza L-Lon. u
had some c'-' m which eg-alates 'uhe,-.ormal s e
~rec-u on the mechanis
level o.-t' 1!Do-oroteins, but had no substantial ef-,---ct on the
course of re-pa-ratory processes after live3~dam-age caused by tetra-
chlorme ludil~g 3 Czech and A, Russian..
'Uhwq. T"hirteen references, inc
2/2

iCZECHOSLOVAKIAL
-V1. VITEK
M. VWTECH%-J~ISKY and R. VFJDOVSKY, Exrerimental
Ther'aFy Research Ins
(Vyz* ...iy usta
Litute u-- -3v rro experimentalni terapie),
Chair of Internal Medicine of Postgraduate Medical College (Interni
lZatcdra UDL), institute Lor Research in Hu-man J.'utrition, and Tuberculosis,
Denartment of Thomay'crAllospital (Oddeleni tbc pri Thomayerove nemocnici)
Prague.
I'llechanism of Psychotroric Lffects of Cycloserine Isomers."
Prague, Acti'vicas Ncrvosa Surcrior, Vol 5, No 2, leffay 63; pp 168-170.
Abstract. Studies on effect.on tryptophan metabolism of d-, l-,. and
racemic cvcloserine rcvealed that the 1-isomer has scrongest LIffect. It
also had tranquillizing and antidepressant effect in 5 of 8 patients
given 50 to 100 mg. thrice daily for 2 to.3 weeks. Five Soviet 2 Czech
(I unpub.) 3 '11estern and I Japanese reference.
10

CZECHOSLOVAKiA
RYSJUNEK,-K. and VITEK, V., Chair of Internal Medicine .(Katedra
'!-n-te'i~yil ' esearch Institute for Experimental Therapy
(Vyskumny
ustuavexperimentalni tuerapie), Prague-YXc, Docent Dr 0. SIDIAEBL,
Dr. of Sciences, director.
"Ef f ect of Pathological Serum on the Oxidation of Adrenaline
Prague , Caso-ois Lekaru Ces ~.ch, Vol CII, No 37, 13 September 631
pp 1021-TO723.-
Absturact [Authors' Enp sh summary, modified]: Investigated was
inhibitory eff,~ict'of normal sex-am and serum of patients with
malignant tumors on adrenaline oxidation. Serum of patients with
a malignant tumor had a,smaller inhibitory effect. Nfo direct
a correlation was found between the Drotein-spectrum of sex-am and
its inhibitory capacity, nor was there a direct correlation between.
U -o w
liver tests and the inhibitory ef-Eect of serum. No relationshi. as
-Lound betwee- the inhibitory effect of serum and the albumin/glo~-'
bulin quotient. No conclusion is made on.the diagnostic value of
the test. Ten references.
13

9(2) CZECH/14-59-2-9/4,61''
AUTHOR: Rysanek, Vaclav, Engineer
-----------------
TITLE: Dielectric AmDlifiers,(Dielektricke zesilovace)
PERiODICAL: Sdelovaci Technika, 1959, Nr_2,~pp 51-56-(Ozechoslo-'-
vakia).
ABSTRACT: The author deals with the characteristics and the''us'e
of ceramic dielectrics. These new materials hav.e',a
very.high d ielectr .iceonstant. with .,great aependance I
on tension,and heat and a particular type of polariza-,
tion. They are known~,under the name: of,.ferroelectries
and found importan-Vapplication:in the construction-
-
of dielectric amplifiers* The. dependancelof the, di-
,..
.
electric constant'.on ension is an essential factor,
in the functLoning of dielectricamplifiers. . Among
these materials are RaTiO which is,~the most import-'
'
~
about
ant, ands SrTiO A.chang
intension can bring
N

a-ch nue of t
dielectric constant 5 l." 11=tu
A her
a g
characteristic o.flferro6lectrics Ii6;their.:dependance
on heat'whi'ch determines,a significant change.An.-the

Card 1/3 n
dielectric consta t, which~increases,parallel to

Dielectric Amplifiers, CZECH/"14-59-2-9/46
ture and reaches a maximum value at a temp r-
temperau
ature called the point of Curie. This"poinu is a::
typical constant of all types of ceramics. The ir.
dependance an frequency is not significant, :The
basic principle of the dielectric amplifier is'the.
nee on tension of.the
exploitation of the dependa
dielectric constant of ceramic dielectrics forming
a thin, flat-condenser whose capacity and iorce de--~,
33end.on.the tension of thF; signal to.be amplified.
There are two types of 8.ielectric amplifiers: tfie
:,non--resonance:and.the resonance type, In the non-
resonance amplifier, the nonlinear capacity used.for
amplifying an electrical signa.l.w6rks in away~~Silni7~
lar to that of magnetic material, in a magnetic ampli-.
fier...With an increase of the.signal tension,:,the
capacity of the conde nser dependent on tension, de-
creases and consequently the reac*tance increases.-,-
The author then refers to thework don.e.in thielfield.,
by Penney, Horchand Sack.: Thefunctioning o f . the
resonance amplifier is based on a'different principle.
Card-2/3 It c an b eused as an amplifier.of tension. I ti 3

Dielectric Amplifiers "CZECH/14-59-2-9/46
Card 3/3

a j IL L -AL-X-,r-o 31 if X x V a a 0 #1 a a M 0

SPFCTRUM ANALYSIS Of METALLIC ANTURMY By muss or.COKPRESSESD
M.ECTFODES. S. V. SOLODOV11K AND A.~ 9. RISAKOV.I(ZVE ST. ANAD. NAUF S.S.S.P.,
1945, (Fit. )~ 9. (6) 636-638) (rn russ an~)' . Spark spectra of tablets
mde frois pondered Sbwre used for the awaysis of Sb alloys containing
'
Pb. Bi, Cu, Sno Ago UP As. Aus
Co, Ni, Kno said Fo owd tablet of,the lines
used are rjvon. 4ynthetic standards wre made froin Sb alloys.:poWored and
00~ -diluted with prive3b. thericher alloys were also diluted for alalysis not
00, that comparisons were only made with < 'r),:) A' ~ r" "-.of the ele ent present in
m
goo
Ge'r the tablet. The method results in a probable
oreor of
365% of the oonc go*
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31i9lO- P6026592 SOURCE CODE:, CZ/0034/66/000/002/0112/0119
-Marie--Rishava, M.; Bizek,, Vaclav;
AUTHOR- Lobl, Karel--Lebel,,,K.; ~Ys~y~~t
Abusinov,~~Mndr--AbusEnov, -A-r-
ORG: State Research Institute for Materials of Construction, Prague (Statni vzkumny
ustav Ea-terialu.)
~,TITIE: Influence of heat treatment upon the structural properties of cast steel
CrlBN.,. 9Ti
SOURCE: Hutnicke listy, no. 2, 1966# 112-119
TOPICTAGS: cast steel, solid physicalproperty, annealing, corrosion protection,
material fracture, metal heat treatment/Crl8Ni9Ti cast steel
ALBSTRACT: The influence of the wall thickness, of mechanical properties. on.the'
annealing temperature, and4the time needed for annealing in the elimination of,.,,
intercrystalline corrosionlis investigated. Isothermalannealing at-750T was
studied; long term heating to 60U- 700*C in materials with.varying ratios of Til:: G
'was,investigated with respect to notch strength and the appearance of fracture,
surfaces. When casting is.made at 700 - 800*G the notch strength is decreased,
significantly because of precipitation of carbides and of,signa,phal3e. Orig. art.
has: 25 figures and 2.tables, [Based on authors' Eng. abstract] [JFRSi
3497791
SUB CODE: 11, 20, 13 SUBKDATE: none CRIG REF: 005 BOTH REF: 001
15.26-194
Card 1/1 669-15: 669o

Lii A fiv e- s t
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------- P_ i-ille Clattsius-Claj)cyron equattod'it N-dedu~cd:
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the nature of the
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to b'! tile auguic
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all rildhis of curvatl
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surfur size Of tile PlAn.'rincielis is defined by Me
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this nucleus and tile Client. jitit - Itial
tile solid.suln., I'lle crit'. size detil., ill t)li:; 'way agrt.,.i Ili
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alf.
study of above dolect shown th&'
urvanoe of decar, des
it is Cau"d by 0"
Incubation pe
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Picture trama, fornustim In bladtismart malleable Iron.
Ri celelfa mand Alarir' F
11 - yk._ Hats irkl Uily 3.2"211-7
l95I)).-Aprrliticc;J in all castings made
i1c a ways occu
=esentemelteve" thew are annrelsial in differtnt Imis:
however, parts anneal"I in the same pot may show different
behAvlor it they orlainsir frout different inelts; the thick-
nem o( the Wight edge of A fracture Is the 3mine as [he inclal.
lographically detil. one and Imalt are equal to the thickn"%.
of the flake-Irce surface lajr~r; while the core of picture
frante I'm puts is a pure ferrite, iiarts with a decarbutist4l
alge relaits a partiv prflitic structure in the core after the
ann"ling prow-%. C. soul R. conclude that the iotro-itY
.4 lite uIchusti."T '11 the steel to lx%-oIuc tualleahle IIA~ a
dee6ive hifiuenvc.~ All fact," I-axibenine the incul-tiou-
e.l., Cr cootVat. inclea'al VC0, Content in
.4ution. It content. presence of nonconitiensated S. Wing
at-nit Octure fnunt Foristation, while all faclon vshich
shorlen the intullation tinies. e.g. increase of the Si content*
inoculation 'etc., act against decarburintion of the Tdg". a
int
I'hcrc arc * fications that the saint can be jai~l about the
fortnAt ion-( an axktixcd surface layer (clay fracture). This
w~ms to represent a second stage of picture frame which dc.
VCJUPS (luring longer su"I More intensive u%M&tjuu.'
Fugene Gros

In

. . . . . . . . . . . . . . . . . . . . . . . . .

I
w
.I
.I
4
,;tl
!f
~

CZECHOSLOVAKIA
RYSANEK, K.: VITEK, V.: SVEHLA, C.: Medical Clinic, Instit-ute.of
Corig. version not iven7
T-ost'g'or-a-M29~rMedical Trainir~g. Prague. 9
"Hydroxylation of Indoleacetic Acid and of Tryptamine In Vitro;
the Action of Monoaminooxidase Inhlbltors.11
Prague, Activitas Nervosa Superior, Vol 8. No 4, Nov 66. pp 373-11,
375
Abstract: The influence of iproniazid and tranylcypromine.ori
hydroxylation of 6-hydroindoleacetic.acid,in vitro was investi--,.
gated. -Liver tissue had 10. t,j;mes as high a hydroxylating
Indole
activity for tryptamine as acetic acid (IAA). Small
Intestine mucosa can hydroxylate.tryptamine to o-hydroxytryp-
tamine, but its 6-hydroxylating potency is only:1/10 that of
the liver. Ipronlazid Inhibited conversion of 6-HT by 161co;
tranyloypromine showed no Inhibitory action. 1 Figure, 1
Table, 3 Wes,tern,.l Czech, 2 Japanese references, Submitted
at the 8th Annual Psychopharmacological Meetirv-c'at Jesanik,
18 - 22 Jan,66. Article is In English

CZECHOSLOVAKIA
RYSANEK, K.: SVEHIA, C.: Institute for Postgraduate Xed1cal Train-,
-TE`g-,'M'd-YdFmT-Cl ini c, Research Institute of Experimental Therapy,
Prague, Kre., rorig. version not given
"Metabolism of Indoleacetic Acid Following Monoaminooxidase,tIn-
hIbItIon."
Prague, ActIvItas Nervosa Sup r1or, Vol 8, No 4, Nov 66, pp
375-376
Abstract: Substances giving kynurenine reactions were found in:
the urine of some people who were subjected to a serotonin.load.
In a follow up experiments on 5 volunteers are described.
When 3 9 of Ia were administered excretion of kynurenine type
substance:3 increased significantly. Chloramphenicalcaused an,-
increase of a much more limited nature. When certain pathways._
of the.IAA metabolism are Inhibited by.MAO Inhibitlon,-other~'
pathways are used. The compositioxi of kynur'enIhe substances
was not determined. No references. Submitted at the 8th Annual
Psychopharmacologloal Meeting at Jesenlk,.18 22-Jan 66.
Article Is In English.

CZECHOSLOVAKIA
1/2
i
m

C ZEC.--.',OS IJOVA;~- LI
RYSAT,=, K., VITIM, V.; I~ediical ClinIc o.--.- Pest-rarllu:~-Iq "'c6ice-I
TftI,:r1uMMu 8',"PrI-Igue; Researcia Institute for
Pra--Ue. /Orig. version not Given-7
T
"The a;:cretion of 6-'Hydroxyla~ted i-Letabolites of I-ndoleacotic Ard
-Poll-owin- Peroral Loadin- with Indoleacetic Acid."
To 66-, pp
Prague, Activi as Nervosa Suporior, Vol 6 No 1, v
378 3130
U4
Abst-ract: Hydroxylation of DkA in the O'tli 7)osition is discussed;
-,ical me.-aing ur! I . --
1 .0
is probai).-y one I
its physiolor, n is cnown, bu Ui.
the detoxication reactions. The 6-hydroxylated com.-ounds of indole.:
affect hhe GNS -,.-,ore than the original coi,,mounds. E~-:creti on of
7
ter a peroral load of 39 of - IAA was s Ludied in 0" la c a 1 tit
6-HIAA a a
ly
jects. excretion of 6-HLUI increased to 26 7?:~ dany fron',
sub
r.- .1 1 1
an original 8.2 mg as a result of the loading. 1 Pi ure 8 ~-Jesu-
c_~
ern, 2 Czech references. Submitted at the 8th Amiual Pr,-jc*---oT)har-
nacoloE.-ical. Mectim- at Jesenik, 18 22 Jan 66. Artl'Cli~., is in Eng-
1 ish .

CZECHOSLOVAKIA
1/1

a
L 29471-66
ACC NA, SOURCE CODE COMOiQ
Amo19979 CZ/0079WOO
Pr ek, Ve
AUTHOR: lZysanokt Ke ague); Vit
ORG: Medical Clinic, Postgraduate M'edical Institute, EKqZue_
TMIR* % * Evaluatio onversion fThis pape
n of the,Sloerdsna tost of serotin c rwas pre-
,sontl ad at the 7th Annual Psychopharmacological Meeting, Jesenik, 20-23 JanuarY 1965 1-1
SOURCEt Activitas nervosa superior, ve 7. no,, 3, 1965, 264
TOPIC TAGS: serotonin, enzyme, biochemistry
a*
ADTINUCT: The test is a valuable indicator of tha.monoamino oxid a irdiibition in
ran if the investigated,subjects havo a rdmiram basic conversion of 50."6, and'if th6'
Variiability of tho convorsion was examanod bofore the test* ~ The excretio.n'of 5-kvdrol'
xyincloloacotic acid rust be chock-ad after moro.than 8 hours after to St An inhibitioz
n ma bo taken as a clear proof of-monoamine oxidase
of conversion larger tha 50p"'
irliibiti=6 fOrig. art. in EnZ.~,cipR-S7
SUB.CODS: o6 SMI DATE i none
Card

29463-66 -------
ACC NR: AP6019986 SOURCE CODE: CZ/0079/65/007/003/0271/0273
AUTHOR: Viek, V.; Rysanek, K.; Voitechovsky, M.
O'aG-.'-Research Institute for Experimental Therapy, Medical School of Postgraduat~_
Medical Institutev Prague; Institute of Human Nutrition, Prague
TITLE: Excretion of tryptophan d catecholamine metabolites after . Za nistration7
jLn dmi
of cycloserine'Ysomers in man ZTh.is paper was presented at the 7th Annual,IPsycho-1
gtr-7
pharmacological Meeting, jesenik, 20-23 january 62/
Activitas nervosa superior, v. 7, no. 3, 19659 271-273
TOPIC TAGS1- tryptophan, biologic metabolism, pharmacology
A---ST?,kCT-. 1-Cycloserine (GS) Is the Isomer that interferes most strongly with
'tryptophan metabolism. CS interference with tryptophan metabolism'is not shown
1.71 the excretion of indo-leacetic acid either in healthy '7 or in sick subjects..
Orig. art. has: 1 figure. Zorig. art. in Eng--7 Z-7PI-1V
S UB CODE. 06/ SUBM DATE:* none/ 0MG- REFt 005 OTH REFs 008/ SOV~REF: 001,1
Card 1/1 fv

C
V. VOT._,~C1TOtr3-cy I.L,
--nd -[JTIc,,, E., Clh_air
1~. - -z of
I i -n-e- - ',-abed -itute for "He Pos'
_e Icil-le L, ni ra) , inst U u
U, r a d u a e iillrairling of _'Physician. L
S (us-, av Dro dosk-olovan~ lek
Research institute -for '2`..-_-oerime-ntal he-any (Vyzkv_mny ustav ex-
Lerimentalni teraDie), __Prag7ze, D-ocen-tt, 0. S-HAIEEL, I-Qu , Dr o-f
Sciences dia7ec-~;or; and institute -fo_r iwt:ritvion Research (,Ust-av
.)r o -,.- .-. I I Dr ol"' Scien-
Pr of iJ.SEK HID
jziaun vyzavy- lidu), PrE4~me,
ces, d:L:,.-ec~.or [_ijiC:"Ii,,ridual wFfliliations can:aot be deteruiinedj.
__sect_ of 2eno" axmaii on the llxcr,~'4orn of 5-1~,,-droWindoiacetic
c-" d and 'etilo.-A-i-4-F-ydro.-.--j-,.qandelic Acid in Nan.
Prague, Caso-)io Le Ceskyeh, Vol CIT, xio 40, 4 Ocu
tober 633,
uthors' 1 1 i s h s u:, LT.
trac' riGdified] A comaparxison. of
Abst Y7
the concentrat-i on of' electroDInoretically divided lipopruteins 2M
ffering I-Prom avitami
(,uinea pigs satva~uted.T,,d Uh vi--amin C and sua,
osis showee, t-hat early stages of 'he C avitwainosis inc-reased.
V
s,-,nificantly the level of x, and.decreased the Ileve! of OC2
liDoDI-oteins. A liver dariage caused by administering., eaz-bontetura-,
ch-loi-ide had a cousiderable effect, on t-he se-rum level of the-:Ii-oo
'02:~Otelrl fractions. in them fi_-st 'u-Yo days of intoxication both the
saturated and z:witan-Lnous gai-nea pigs showed an increase -of the
1/2

C~,,ECHOST,U1.4IT'j I
P~agae, Casoi)is Iel:~--u Cesi-.,r Vol Cli-, i,1040, 4 October 63,
L -L.' ch
pp 1099-1102.
i 'ei
---d O-f"---ac~uions , in d adro-o of the oc~.--ra-ction o -rjoDrot
On tI-Ie seventh day, after CC!,-, admi-nistration, botil- san-.Ln-aued and
showed a conspicuous tendency for normal-
avi -a-Minous r,,,ui-nea pigs
u
'esults:T)roved that the early stage of the,C avitaminosis
iza L-Lon. u
had some c'-' m which eg-alates 'uhe,-.ormal s e
~rec-u on the mechanis
level o.-t' 1!Do-oroteins, but had no substantial ef-,---ct on the
course of re-pa-ratory processes after live3~dam-age caused by tetra-
chlorme ludil~g 3 Czech and A, Russian..
'Uhwq. T"hirteen references, inc
2/2

iCZECHOSLOVAKIAL
-V1. VITEK
M. VWTECH%-J~ISKY and R. VFJDOVSKY, Exrerimental
Ther'aFy Research Ins
(Vyz* ...iy usta
Litute u-- -3v rro experimentalni terapie),
Chair of Internal Medicine of Postgraduate Medical College (Interni
lZatcdra UDL), institute Lor Research in Hu-man J.'utrition, and Tuberculosis,
Denartment of Thomay'crAllospital (Oddeleni tbc pri Thomayerove nemocnici)
Prague.
I'llechanism of Psychotroric Lffects of Cycloserine Isomers."
Prague, Acti'vicas Ncrvosa Surcrior, Vol 5, No 2, leffay 63; pp 168-170.
Abstract. Studies on effect.on tryptophan metabolism of d-, l-,. and
racemic cvcloserine rcvealed that the 1-isomer has scrongest LIffect. It
also had tranquillizing and antidepressant effect in 5 of 8 patients
given 50 to 100 mg. thrice daily for 2 to.3 weeks. Five Soviet 2 Czech
(I unpub.) 3 '11estern and I Japanese reference.
10

CZECHOSLOVAKiA
RYSJUNEK,-K. and VITEK, V., Chair of Internal Medicine .(Katedra
'!-n-te'i~yil ' esearch Institute for Experimental Therapy
(Vyskumny
ustuavexperimentalni tuerapie), Prague-YXc, Docent Dr 0. SIDIAEBL,
Dr. of Sciences, director.
"Ef f ect of Pathological Serum on the Oxidation of Adrenaline
Prague , Caso-ois Lekaru Ces ~.ch, Vol CII, No 37, 13 September 631
pp 1021-TO723.-
Absturact [Authors' Enp sh summary, modified]: Investigated was
inhibitory eff,~ict'of normal sex-am and serum of patients with
malignant tumors on adrenaline oxidation. Serum of patients with
a malignant tumor had a,smaller inhibitory effect. Nfo direct
a correlation was found between the Drotein-spectrum of sex-am and
its inhibitory capacity, nor was there a direct correlation between.
U -o w
liver tests and the inhibitory ef-Eect of serum. No relationshi. as
-Lound betwee- the inhibitory effect of serum and the albumin/glo~-'
bulin quotient. No conclusion is made on.the diagnostic value of
the test. Ten references.
13

9(2) CZECH/14-59-2-9/4,61''
AUTHOR: Rysanek, Vaclav, Engineer
-----------------
TITLE: Dielectric AmDlifiers,(Dielektricke zesilovace)
PERiODICAL: Sdelovaci Technika, 1959, Nr_2,~pp 51-56-(Ozechoslo-'-
vakia).
ABSTRACT: The author deals with the characteristics and the''us'e
of ceramic dielectrics. These new materials hav.e',a
very.high d ielectr .iceonstant. with .,great aependance I
on tension,and heat and a particular type of polariza-,
tion. They are known~,under the name: of,.ferroelectries
and found importan-Vapplication:in the construction-
-
of dielectric amplifiers* The. dependancelof the, di-
,..
.
electric constant'.on ension is an essential factor,
in the functLoning of dielectricamplifiers. . Among
these materials are RaTiO which is,~the most import-'
'
~
about
ant, ands SrTiO A.chang
intension can bring
N

a-ch nue of t
dielectric constant 5 l." 11=tu
A her
a g
characteristic o.flferro6lectrics Ii6;their.:dependance
on heat'whi'ch determines,a significant change.An.-the

Card 1/3 n
dielectric consta t, which~increases,parallel to

Dielectric Amplifiers, CZECH/"14-59-2-9/46
ture and reaches a maximum value at a temp r-
temperau
ature called the point of Curie. This"poinu is a::
typical constant of all types of ceramics. The ir.
dependance an frequency is not significant, :The
basic principle of the dielectric amplifier is'the.
nee on tension of.the
exploitation of the dependa
dielectric constant of ceramic dielectrics forming
a thin, flat-condenser whose capacity and iorce de--~,
33end.on.the tension of thF; signal to.be amplified.
There are two types of 8.ielectric amplifiers: tfie
:,non--resonance:and.the resonance type, In the non-
resonance amplifier, the nonlinear capacity used.for
amplifying an electrical signa.l.w6rks in away~~Silni7~
lar to that of magnetic material, in a magnetic ampli-.
fier...With an increase of the.signal tension,:,the
capacity of the conde nser dependent on tension, de-
creases and consequently the reac*tance increases.-,-
The author then refers to thework don.e.in thielfield.,
by Penney, Horchand Sack.: Thefunctioning o f . the
resonance amplifier is based on a'different principle.
Card-2/3 It c an b eused as an amplifier.of tension. I ti 3

Dielectric Amplifiers "CZECH/14-59-2-9/46
Card 3/3

a j IL L -AL-X-,r-o 31 if X x V a a 0 #1 a a M 0

SPFCTRUM ANALYSIS Of METALLIC ANTURMY By muss or.COKPRESSESD
M.ECTFODES. S. V. SOLODOV11K AND A.~ 9. RISAKOV.I(ZVE ST. ANAD. NAUF S.S.S.P.,
1945, (Fit. )~ 9. (6) 636-638) (rn russ an~)' . Spark spectra of tablets
mde frois pondered Sbwre used for the awaysis of Sb alloys containing
'
Pb. Bi, Cu, Sno Ago UP As. Aus
Co, Ni, Kno said Fo owd tablet of,the lines
used are rjvon. 4ynthetic standards wre made froin Sb alloys.:poWored and
00~ -diluted with prive3b. thericher alloys were also diluted for alalysis not
00, that comparisons were only made with < 'r),:) A' ~ r" "-.of the ele ent present in
m
goo
Ge'r the tablet. The method results in a probable
oreor of
365% of the oonc go*
VW .
.
o
of the element estimate Id.- E. van S,

00
A a - L a , ETALLUPWAL LITERATLAC CLASSIFICAT100 C-Z- a

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PROC91683 &No PaGpIlrill Not.

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.
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i
mil
(temper C.5 by Irtrilts) W Multheirt 106
t -
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th
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cvrn it thry aft awwak-d in di&-frat t&; Ird
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the t may bcbavt difierv
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96 thicknesa of the bright rim of a frwAwc is thr same
f
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Al that of the flake-frer surfacCi laYVr- (c) N%lii
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Wit""
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aGNIibilM commoaleck in On, www 1-1 inny
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bright nns of a froi-ture jO 11- 44,10- ~If t6' Oft"-IM~
awfam lmyW; 13) whi6i Om -n-f on-mi. will.n.1 Wit['- c~.
let
I- J~N~ lrffd~. Pon. with a W~mlmoftl "in rVtain a j4rll~
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is-,r- ao,II FrO iii -4mI m" bydroam a-
'11. mkw In Alwon, ariel iri~ulavicbn, trtul to ~ivppf-d~mr

L AOCIALLANIISKAL WERATUR11 CLAISOKAICS
salvo
soma Nill 4-1 dot 4" Alk
u it As 20 u ,
is W P b PL t r
W st a
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- - - - - -
We'.W-6

JDZU
31i9lO- P6026592 SOURCE CODE:, CZ/0034/66/000/002/0112/0119
-Marie--Rishava, M.; Bizek,, Vaclav;
AUTHOR- Lobl, Karel--Lebel,,,K.; ~Ys~y~~t
Abusinov,~~Mndr--AbusEnov, -A-r-
ORG: State Research Institute for Materials of Construction, Prague (Statni vzkumny
ustav Ea-terialu.)
~,TITIE: Influence of heat treatment upon the structural properties of cast steel
CrlBN.,. 9Ti
SOURCE: Hutnicke listy, no. 2, 1966# 112-119
TOPICTAGS: cast steel, solid physicalproperty, annealing, corrosion protection,
material fracture, metal heat treatment/Crl8Ni9Ti cast steel
ALBSTRACT: The influence of the wall thickness, of mechanical properties. on.the'
annealing temperature, and4the time needed for annealing in the elimination of,.,,
intercrystalline corrosionlis investigated. Isothermalannealing at-750T was
studied; long term heating to 60U- 700*C in materials with.varying ratios of Til:: G
'was,investigated with respect to notch strength and the appearance of fracture,
surfaces. When casting is.made at 700 - 800*G the notch strength is decreased,
significantly because of precipitation of carbides and of,signa,phal3e. Orig. art.
has: 25 figures and 2.tables, [Based on authors' Eng. abstract] [JFRSi
3497791
SUB CODE: 11, 20, 13 SUBKDATE: none CRIG REF: 005 BOTH REF: 001
15.26-194
Card 1/1 669-15: 669o

Lii A fiv e- s t
the 0 efit
Vsava
to-,

1
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Distr; M.
4B
j
,
aguIg 0 A oys., Marie Ry�a AL Ad
tri f
"ne theory-of
tistay A m tic - St
-7-
I& I n icki IA!FTS 'f 0 RM2
g
------- P_ i-ille Clattsius-Claj)cyron equattod'it N-dedu~cd:
n3m
itily. curve is detil witi, tile sign Of %'0 1
the nature of the
-
and
nr. soln.
of the systein and tile reaction heat duil
cla,,
'

reasofil r the,
the element frinn'tile!sol
f e
!%
pp. Tit
supersatn. in tile solid soln~ during litietichilig Is considered
t',Ltit)ll Of tile tile"
to b'! tile auguic
n
,
'
all rildhis of curvatl
tr6 of its
at irn
potential of -tile particle
surfur size Of tile PlAn.'rincielis is defined by Me
-
1 tile therrawlitt',intic ilotentild nf
'ity 6f tile cjl~nl.
ant
this nucleus and tile Client. jitit - Itial
tile solid.suln., I'lle crit'. size detil., ill t)li:; 'way agrt.,.i Ili
tile splic-lical nuelcus with Lite nsual definition.

7
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.SUBMITTED 2 7:9.1

a
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-"UU A
almokkosia Aliffigodimp Irem 11"
Csoch.) Jlrf Coloda and Marie Ry"vaL
-kd LUty, V. 8. June low, V721- 701
alf.
study of above dolect shown th&'
urvanoe of decar, des
it is Cau"d by 0"
Incubation pe
0* A)!; burls* Ion dttjVOS
Hod 01 Stop itlat on of the comon-
tit@, The principal factor is, there-
bilizability of the iron.
the Incubation
fracture. and
P-1 I
ales
glj~e
ass
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too
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Picture trama, fornustim In bladtismart malleable Iron.
Ri celelfa mand Alarir' F
11 - yk._ Hats irkl Uily 3.2"211-7
l95I)).-Aprrliticc;J in all castings made
i1c a ways occu
=esentemelteve" thew are annrelsial in differtnt Imis:
however, parts anneal"I in the same pot may show different
behAvlor it they orlainsir frout different inelts; the thick-
nem o( the Wight edge of A fracture Is the 3mine as [he inclal.
lographically detil. one and Imalt are equal to the thickn"%.
of the flake-Irce surface lajr~r; while the core of picture
frante I'm puts is a pure ferrite, iiarts with a decarbutist4l
alge relaits a partiv prflitic structure in the core after the
ann"ling prow-%. C. soul R. conclude that the iotro-itY
.4 lite uIchusti."T '11 the steel to lx%-oIuc tualleahle IIA~ a
dee6ive hifiuenvc.~ All fact," I-axibenine the incul-tiou-
e.l., Cr cootVat. inclea'al VC0, Content in
.4ution. It content. presence of nonconitiensated S. Wing
at-nit Octure fnunt Foristation, while all faclon vshich
shorlen the intullation tinies. e.g. increase of the Si content*
inoculation 'etc., act against decarburintion of the Tdg". a
int
I'hcrc arc * fications that the saint can be jai~l about the
fortnAt ion-( an axktixcd surface layer (clay fracture). This
w~ms to represent a second stage of picture frame which dc.
VCJUPS (luring longer su"I More intensive u%M&tjuu.'
Fugene Gros