SCIENTIFIC ABSTRACT SORM, F. - SORM,F.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001652420017-3
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: August 26, 2000
• Sequence Number: 17
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

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I CZ/8/52(82)/10-26/39
AUTHORS: 6orm, F., Keil, B Holey5ovsk-Y, V., Meloun, B.,
Mke-g-,O. and Vani@ek, J.
TITLE Proteins.XLIX. Comparison of the Microstructure of
Chymotrypsinogen and Trypsinogen. Prelimin
Communication (0 bilkovinAch.XLIV. Srovngn
mikrostruktury ch5motrypsinogenu a trypainogenu.
Predbeing sdglen-i
PERIODICAL: Chemick4 Listy, 1958, Vol 52(82), Nr 10, PP 1992-1995
(Czechoslovakia)
ABSTRACT: This is a continuation of tho discussion on the micro-
structure of proteins in which the authors draw on their
own experimental results (previously published) and
those of others. Attention is drawn to the repetition
of certain peptide residues in the two proteins
considered.
There are 3 tables and 34 references, 12 of which are
Czech, 22 Western.
Card 1/2

CZ/8/'52(82)/10-26/39
Proteins XLIX. Comparison of the Microstructure of Chymotrypsinogen
and Trypsinogen. Preliminary Communication
I I
ASSOCIATION: Biochemicke odde"lenil, Chemick@ ustav,
deskoslovensk& akadmie v6d, Praha (Biochemistry
Di'vision, Institute of Chemistry, Czechoslovak Academy
of Science, Prague)
SUBMITTED: March 13, 1958
Card 2/2

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k'THORS@ P*jxos-, J. " gorn P. CZ19CH/8-52-11-15/30
TITIN: Oi Steroids (0 stridech) XXIIX. Splaer3c 2- arl 4-trox-
Derivatives of 3-otoacl-ost.no (InU. lp.'=@raf 2@broz
a 4-broadarivity 5-ketosadrostanu)
PERIODICLL: Chomlck@ Listy, 1958. Vol 52. Sr 11. PP Z115 - 213!
(Czechoslovakia)
A63STRLCT. The prtparstlon of the epizeric 2- and @tromndertvatlv*s
of Andro6terone, 3o, 17.3-d1ridroxyAndrostaze,
3117-dIketoaAdrostace and d.-hydroteaccaterofte or* des-
cribod The original bromohydrits were ;r,p&:.d ty tLe
docamp;sItion of the related ap.2x1d#s and reaction.3 uvr:
'
carried out to prove tt.* structure Of the stated ZAterl 's.
The 12. spectra &Ad optical rotatton of tht *plmerlc
2- w%d 4-broso-5-katoderivativ* are discussed. & prowtoua
report (Rot 1) has described tLe preparation of a series
of steroidal hormone analogues *-.tb a brozo-substitl4ent
In the 16 position. The 2- " 4-broao-derlvatlvea -ere
staued to stow the effect of substitution an ;rya;.olog'.cal
activity of the hormones. It use considered at tte sazo
Cardl/4 tisto that these substances would be of Interest from the

steracbealc&I and spectroscopic view"Int for the dis-
placement of %Le c&rboxyl maxlza In Uroacketomes for it
Is possible to Infor the configuration of tX* tMzjno
Atca and even, In certain cases, tzo eouforzatLom @f tr..
related ring. The structures of the various compound& r"t
discussed In considerable detail. The following prvp&rat@oz.-i
ar* gIv*Az 2o,3a-*pozy-I?-itoto and-rostame; 2j-bM"-3a-
tjdrcr:-I7-koto aAdrostaus;
&nd.rostans; 20-broso-3a-acato7,7-173-bydrozyandroat~s;
20-b"ao-3a.170-dl&cstoxjandrost&"; 20-brozo-3c.190-
acetoxyandrostane; 1?D- ace toyj azdra &Lane (2);
2a, 3a-spoxj-170-sce to)Va nd" a tans - 3a 4a-opoxY-l7J-
toxyandrostane; Za 3a-
Zj 5%-dta,#toj$-
17-keto andr,sto-no; 213-acetaxy-3a-rosylov-17-'4*to-
AAdrostano; 20.30-#pozy-17-ketoandros taut t
0.30-opoxy-170-bydrnandr &tans% 23-broxo-3,17 dikwto.ndr-o-
Card2/4 !to"; 20-bMw-33,I9D-d,iLy rorJandrostate; 21-broso-30.
170-41acetoxyandrost*val 3-kera-173-bidroxyandrostono;
Zm-braoc-3;1 I7D-dj1tydroxyardMsta=o, 2m_brQ=*.3j3_j'.-j_
d1scstoxya;;AMszazot 2,1-brozo-3-4*to-llii)-acdtoxjxr.4rcat&,A;
2a-brcao-S keto-173-acetoxyanirostame; 23-bromo-3j.
bsdroxj-I'j0-acw toxy aniro a tame; 2a-bMzo-33-hydMxy.l',1j_
3Q,4Q-*poxy-l7-k*t*ndMst&r,*;
.'t y 0-bromo-17-k*tcamd atone, 3Q_ryd.Mxj_j_
ires. 152stame
et", azdra scal 3Q_acotoxy_Q_bMxo_li_,4to_
abdrosts.no; 5. TdIk* Zo:Z3-b Moo andro *tans; 3,17-dikoto-
#WIL-bromoondrosta". 3Q-AcetcXY-4.)-brow-273-acetaxyar4--o-
t&A@; 3Q.l?1)-dlACotoXy-43_bM andro6taAftj a.*to-41f.
:rQAo_ tans' .
androstama. 3 itsta-170-acatoxyLadrostano (4).
Tb4rf are I figure, I table and 2@ references, 2 of wtjct
are CS*Ch. 15 Snglish, Z Swiss and - German.
Car43/4
ASWCIATZO"s Odd;ltmf pffrodnfch
CtakcslovomskA ... do,
.j* -01. Praha (D&v, wm or
ftt-cl Products, It"
Ac.04., to of Ctl*x1atry, C.*c4')dljv'"
_5UhUITTXD' Ik-Ich 12,

AUTHORS:
' Mikes. 0. and CZRCH/6-52-1-1-2,@/50
TITLS: '--
J?optLd.tc Growth Factors (Peptidcic' rastovi stizulatory)
121- -100lation of a Peptidic Growth Factor ?rum an
2=72AUC HYdrolimate of Caseln (111. Isola Ptidlck;.%c
C
P
mlaivroke-taktoru a eovxatictska Aydr*aitu
k:.
.Inu)
FMODICLLt Chealckhlat 19rd, Val 52 rr 11, p; 2160 - 2168
l
+ 2 112 platemi
dz*c oslovaltisi
ABSTkACTs wain-active
A SiApl@ LOLL04 Of *XtraCtLOV. Of strtpt
P*p%Id*s froa a partially (qnzyzatIcAlly hy@lrolYsed
j
eavein (Pronulan - Britlab manufacture) is C@.Yem It
Is baa
d on &A ItAtial caumtercurrect fractlotatlQn in
Craig ounttr-ourrent zschim* )pLemal - vater ayatem)t --It=
:
@reparative paper-
-d flnslly
on cat1*4-oze"O'" resins Zr
chromatography and preparative p par electropLareslx to
:
ion-ezcLaz@@e fraction.
give &A active traction T . Th
&%Lou gave three troupe (Inactive trtaic, active neutral,
;ctlv* acid). A pure simele bexapeptidt was Isolated
ron the acid traction and tLi* sh@-ed activity in the
blo-=Af with Lactobatillus cas*,.. It was &Lawn to
408t sol aspaxagine. I mol supartic acid, 2 tal
C.r4l/2

LealeucIno &Ad Z tol praline. A-diultro;benyl aspartic
acid was fouild In the bydrolyeate of the 4lmtropL#nyl-
derivative of the peptida. Tne structure may t-hus be
Asp. (Lap MR2 Pro 2' 11SU2)
or
'SP'
fters mrs2 figurea, I table and @5 references, 10 of
which are Czech and 5 English.
ASSOCIATIM Slochemicki odd.'..d CLsZ1'Ckj Ustav, Eeckoolovellaigg'
akademis v(d, Praha Iblochealstry Departzont. Imj,-.-tuta
of Chealstry, Czechoslovak Ac-Sc., Pr*gue
509111 t Sovoab*r 4. 1957
card 2/2

AU"HORS: U.. HzrAk. r. ar@d !@rz T.
TITIZ; On T1 Z45 (0 tor;enech) XC-VlI. !:,* Constitution of
L.d.ll*XCVIL. 0 1-d-lu)
FZRIODICLLi ChemicicsILiit:, 195,61 V211 52, Nr I' I pp 21,58 - 21qO
(Czechoslovakia)
ABWRACTS Kiryalov (Her 2) proposed I for 19dal (C15"2603 a
"squiterpons Isolated from L*duz -,&.'uatr4 and certain
other plants. Title structura Las te*n criticleed by
do Wo and by laboy and 7--hertor. CR f -). The "Itzer - -
showed the absence of an absorption Md In the r*,310A
the Infra-red s;*ctre of ledol. which
5C24 - 2058 cc In
Is characteristic for c7c-opropano rL"s with unsubstit
mathylons, 6roups, On the basis of ttis observation and
certain further resuats, wrich the authors now report
in mor*,dot&il. two alternative 4-rUCturtS. II &Zd 111,
are propostd. analogous to the struct@rws " f globulol
and Lromadendrens. In the Infra-re! spectra of ledol and
desox,yledol the authors failed to ottaLa &a absorption
C&rdl/8 band of about 1173 ca-1, which corresponds to an Lan-
p3op7i gi;@up. (Desoxyledol Is roduced from Ledol
by bydrogenalyols of t he alcohol group. Both.Kox2pa
(Her 9) and lir)alov (Hot 10) cal. It 4-1hydroltdone and
fall to d1ff9rr%.1mt* it from the dehydration Lad
hydrogenation products of ladol. Its Infra-red spectrum
Is similar to azvmadsndr&=* and dif.'ars fundamentally
fro:rtb.@Apectrum of it&dlnano.) 'Le required frequency
see a 0 7 in the spectrum of *t*trmb4droI*daiecs0.
This derivative is produced by the hydrogenation of
Unsaturated bjdrocarboD8 .1-th two double bonds obtained
from lodol by the action or alcoholic "'. %-a*
"action leads to the detjdzation Lad degradation of the
c:clopropone rtzg. CL*m-lcal evidence also oxiaze which
support* 11 &ad III . With the op*ninL7zho c:c lo;rop*ze
ring with R Dr and the dobjdrota;zgena%.-o= of bromo
derivative produced with collidlIns an unsaturated h7d"-
carbon was obtained, the ozonioa-l;z of rich :Ioldod
acetone, formaldehyde antl a r
at . C:11%u a of higher ketones.
An absorption band I-X was discovered in the
C4Lrd2/8 lata-r*d Spectra of the higher Xeton* aiz't%Lre, which Is
characteristic for carbot4l groups In seven or higher-
&sabered rings. SMIllar result* war* also obtaized by the
nisation of the hydroca--bon prt;ared by the
Zfodosozyl*dol GA sil:.ca colu.@r@. So direct evi.4soce
:
yet been given for xLe pasitijr-ln& of "a tertiary U:d
iup an the five-meabtr*d rir4@ of led:l; Xiryalov
r1q;l) showed that the hj'iroxyl is 0. Arbon wa-ch also
had a setbjl group. After Zte oxidation of ledena (IV)
with INW4 (both derivatives are formulated on the beat
of the I*dol atruc%@r* for at--plicity) the autbara laol:t.,,
&part from the main ;rcd,@:t, the dio. C 153260.2 already
described by Klryalov (11955) ry4roxyeatont T in saa.11
Quantities. Thl, po&4@a"&, according to Infro-rad
measurements, ax: togrup In the fly*-a*mbered ring
Cob"rption bead Z I @A-s cm-I ). Kirfalow observed an
interesting traxaformAtion, on corv*rt&ng the diol
Cl5ll2602 %a a decalin derivative (4saign*4 atr=tkLr* TI)
this reaction cannot be a aLzpl* pinaeoline transformatI...
According to the amitharoz wives. tr.# %tLr**.cwabwred ring
par%itipates in a reaction witz Ayza nixed z*cb&"&a
wblch can only be fOr-lated with certainty on the t@aala
of the formula 11 for l*dol. by ZLO *cL*" ; VjI- VIXI
The establishing of the actual structure of the 4&cmjju
derivative end verificat.,on, of Us 1*401 structure is
US XubJect 0.1 turtier w@ra by tr.* eutLrs.
Mwerim*ntal. D0403LY-0-301. 'L*trakj!r*l#dd1sn#* and ledco.
::rs prepared according 'G JtLr4al*v ( 11-451). The products
to Purified crromatcC.-sphically on LI 203.
,01 Dosoxjltdol (@J- or,)
INCH"
If a. cc rouo acetic acid (- &I.)
tur&604 with *,Iroesn tramld*. Alt-r 3 hours' shaming
NL 20 C the mixture, 111 wr-Ich two layers bad f4rced, ra,
red into water (10 &1.) &n,j the neutral produ,t jgols,@
Coluz1he usual procedure. 11,ftl0ecu was determined d@r*ctly
after evaporation.
For C15IWr Calcul.-.od. 27.&-.@ Hr
youlwk. hr.

CZXCK/ 6- S2 -I 1- 2 6/ @O
On Terpeass =11. The Constitution of LAdol
ro derly.tly- 11 C-@Ildlee
4Frr.2t:'.0@',W'NN'2' @vr..2:A 0 [goo Z@@,) %as tett.4 to
boiling point for @ hours w4tL collidin* (@C 411.). L
calo%rloss liquid (490 ad ; B.Pt. ll@_lid P =) -as
Isolat*d by the usual proced-@re. C,02,6(20c..) -
Wculateds 67.50% Ci 12. a
Found& 87.2e% C, 12.69% H
0.22 mothyl.. double bonds .*.-a found by the Saves (Rof Il)
asonimation zatbo4 for the datercl@%Ioz of notbilena
9"u;$.
Isomerloation of lies Gel
Daso a r -41,11ca gel colv.=
gliledol ki-193 6)
(9 heated witz bazzyl&lcotol. The oluted hydrocarbon
Cl*gLrtd of the desorbeAt by chromatography an an
'411MI. A.1 2 03column (10 g; akt.I-11 ). The product 14
acolourless liquid (59.8 ad; B.Pt. 123-124 o/9 zA) which
9 ves &a Intense yellow colour with tatraultromethace.
C15,26(200.4) Calculatolt 57.30% C; 12. ?CP)6 8
round4 87-15% C1 12.64% a
The loves QsoalsatLon method for zzethylene groups Save
0.26 aethilena double bonds.
Pfi:o=;tt1:n oldtilUns:,tF&tC*15gvdrocarton. -
rat; rl c on ag) ouLainet by the
dohy,irobalogenAtiou of the tro=odrivative by collidine.
was asoulsed for 45 &In in acetic &old. The reaction was
diluted with water (10 al.) and reflux*d for 15 min.
5 al. was distilled off from the mixture into a cooled
receiver and th& mixture of t_10.er ketones volatile in
Items sapsrat ad off. Us distillate we& Cleared of
rarmaldo@do by haatirg wMt & saturated aqueous scl4tilaa
of KMW,, 5 al.) and the residual volatile products at
the asoalsatioa steam distilled once more.
2 4--dInitroph@AqtjdrLs8n* 'prepar*d from the distillate
U1 ag; Z.Pt. 5-12b C) did not give a depression .1th
&A authentic sampl* of the acetone e.@d1n1tzopherjlhydrAso".
C9NjOA,04 (238.2) Calculated: -5.3c".4 Ct 4.20 H; 23-5N .11
Found: '65.11% Ct 4.50% H& 23.3N .4
Paper cbrOMAtographq of this to a 4inethyllorm"Ido-
Gyclohsxa" system kRef 13) hal an R. - 0.37 as did
the authentic &le of the 2.@dinitrophoaylhydrazoze of
acetone. 1: The masottLrated Lydrocarbou (M xe) ottalzed
by the lsoa*rlaatlon of dosoxyledol on allies gel
.odor am" logaus conditions to A, the d1.n1tro;hAoylbjdra&ar.*
of mc.n@ (135 us).
V. Iade.. (1-113 6) in acetone (40 al.)
&M.M.strom MA.; was CXWSed, with water cooling
shaken with ZXW, (1.8 6). The neutral product Isolt'*1,
b the usual procedures
): wr=zstographod on us@tral
'U2 05 (activity III-IV (B.Pt. 265-l-,0 112 an)
was elated with b*natne.
C,592402(236.4) Calculated; 76.22% C, 10.244 9
round. 76.4.9% C. 10.4@% a.
The first fractiom olutta with at),
'or contalned the
GrYstalll." diol d*scrlbad by Klrjslov (1951)
(015%602 B-Pt. 151-152 C).
I . are 13 reference , 3 of which are Czech, a jz6lt@
r
And 1 :rALan.
ASaOCIATIOR Odd;lonf pr1ras:4ch 141toic ICrealck; ustav,
,,,:k*&I0vsuMAif eked al* vJ4. probe N tur&l Products
An. isLan.41natituto of CLfaidtrf, Cz*cbcolovaLin
SQ.. ague)

Mechanism of the rearrangement of "sdurn olithalate
and carboxylation of potassivin benzoate. jostf Ratuskg-
and Frantilek Sorm (Cftkodov. akad vid Praguej.
anits. of
0 d KxC% with 10010 powd. a 60 min. to
05. . sealed tube in an autoclave yielded J@-CJ-IACOH)i
(1) conic. approx. 50% of the specific activity of CO& used In
the reaction. Heating similarly an equimolar mist. of
BO, KOCIO, And.211 80 Min. to 410-20* gave I conic.
85.5% and PhCOH conic. 33.5% activity. . On the basis of
this evidence as well as of expts. with changed cunditiom,
the authors suggest that in the course of thenual rearrange-
ment of X phthalate only I C0,11 group of its awl. under.
goes statistical exchange with C% from the reaction atin.
il
l
I
h
b
i
f PhCO
l
ti
i
X
t
e car
on o
on r
nutr
n t
at
as
reac
oxy
a
I
y
9
11 with
results In statistical exchange of the benzoate C
labeled COO and the casboxylation proceeds tu-the further
step with benzoate already labeled with C'4. Reaction
mechanism are discussed. L. I-AL*mek
Distrs 4E2a(j)

Diatr: bE?C(J)
b-3
/ManufactuftS t*M'hthaJU add by theimal rearrsaW
most of lIQM$".--T!&WdV7R&t j Fri
@jsod PrantVA
737793W.-My K SopHUBLIaLe t1l
Czedt. 01,60s, Sept.
(48.4g.)wW2g.Fepo*derhesLtedqukklyinsLnaitt
with 30 atm. CO, to 4"0, the temp. kebt. 30 min.. the
"I y powd. tnaterW extd. with 3 1. hot water. the
light g tertd off, the dear hot filtrate treated with HCI,
CS
thV.Yh3tItfej t. sq)d., boded with water 4 times, filtered,
and dried re hrs. at 140*/10 mm. Save So S. terephthalic
"M (ED, which yielded a di-Me ester, m. 140*. Other
examples featured powd. Zu and Cu as catalysts. temp. 410-
MO. wA mixts. of 1, 11. and X phthalste as starting ma-
tedab. L. Urbinek

17 ( 0) SOV125-5@-6-13149
AUTHORs Sorm, FrantiTek, Academician ((@5i)
TITLE: What is now in Cancer Re3curch
PERIODICAL: Nauka i zhizn' , 1959, Nr 6, PP 28-30 (US,7111)
ABSTRACT: The editorn firrt cive a short bio,,raphy of the zot-or 0-ran-
tigel: "(
Oorim), born 1,013 in PraUue, Doctor of Technical :!cien-
cc3, 111ember and Vice-President of thc Academy of @+cicn^i_31
Director of the Institute of Chemi3tr,; dAtt@'.cied to the
same Academy, Active 114ember of both the joviet and the
German Academies of 3ciences, and JTonorary Ye,-.br@r o" tho
HiuiCarian Academy of Sciences. The author then rc*c@rts on
the contemporary situation in the anti-cancer ntruC,71c in
general, and in SR in Dartictlar. Particular attc;r%tion is
paid to d!ooxiribonucleoproteid, discovered by the Inotitute
of Chemia'.vy Attach.-d to the Academy of Sciences, 63R, to
nucleinic acids (D"K, i.e. desoxiribonticleinic acid, anl
RNY, i.e. ribonucleinic acid), and to ti.,o new a' : t i c'!*ncr.,r
preparations: the 6-azouracil an,,! the 6-azoilracilribozid.
Card 1/2 The author is optimistic in r-spe@,,t to the fin@-.! -3ucc ss of

SOV/25- 314 9
71hat is nr---.-i in Cancer Research
the anti-cancer crusade. There are 2 photos and I drawinG.
Card 2/2

SORM, Yrantinek, Maidomik; KNIWVA, Ifolona, Dr.
Effect of elementary sulphur on antibody formation. Neoplasma, Bratial.
6 no.1:27-30 1959.
1. Inatitute of Chemistry, Czechoslovak Academy of Sciences, Praha 19,
Na evicisti 2. Prague.
(ITMOPIMMS, extracts,
nulfur-containing tumor extract, eff. on antibody form.
(SULPM, effects,
sulfur-containint tumor extract & free sulfur, on antibody
form)
(ANTIBODING,
eff. of sulfur-containing tumor extract & free sulfur on
antibody form. )

XARA, J.;SORM, F.
Adenosinetriphosphatase as the factor inhibiting the enzymic Ayn-
thesis of diDhosphopyridine tracleotides in the tissue of rats and
mice with transplanted tumours. Neoplasma, Bratisi. 6 no-3:225-235
1959.
1. Department of Biochemistry, Institute of Chemistry, Czechoslovak
Acnderq of Sciences. Prague, CBR.
(LDWYLPYROPH06PHATA611, metab.)
(NUCLZCBIDMB AND NUCLAOTIM metab.)
(NIOPIASMS metab.)

.BHQRM;-r. [Sorm, V.I. do)ctor tekhn.nauk, akademik (Chekhooloraklys)
Now developments in cancer research.- Nauka i zhyttia 9
no.10:60-61 0 159. (MIRA 13:2)
1. Vitae-proxident Chekhoslovatskoy AN, direktor )Dnimichaskogo
instituta Chokhoolovatakoy AN, deystvitel'W chlen Cheldioslovatskoy
AN i AN SSSR, pochetnyy chlen Ugorsko7 AN.
(CANOM RNSFARCH)

SORM, F.; MIKES, 0.
"Growth factors with a peptic character.* IT. Chemical properties of growth
factors from protein hydrolysates. In Geman. p. 1525.
COLLECTION OF CZECHOSLOVAK CMYAICAL CGHMICATIONS, Fraba, Czech.,
Vol 24, No. 5, MaY 1959
Month-ly List of East European AccesslonB (EFAI), W, Vol. 8, No. 6, Sept. 59
Unclassifi6d

SORM. F.; SUCHY, M.; HERCUT, V.
*Terpenes.* XCVIII. Proof of structure of arctiopicrin with a note on its
stereochemistry. In English. P. 1542.
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, Prahs, Czech.,
Vol. 24, No. 5, May 1959
Monthly List of East European Accessions (EF-Al), W, Vol. 8, No. 6, Sept. 29
Unclassified

SORM, F.; KEIL, B.
11 Proteins." XLVIJ. CyBteic-acid peptides from. apartial chymotrypainogen
hydrolyeate. XLVIII. Cysteic-acid peptides from a partial trypain
hydrolysate. In English. p. 1558.
COLI-ECTION OF CZECHOESLOVAK CHEMICAL CWUNICATIONS, praha, Czech.,
Vol. 24, No. 5, May 1959
Monthly List of East European Accessi,-ins (EEAI), W, Vol. 8, No. 6, Sept. 59
Unclassified

rill r"V7, A,
7 e,,@ h o s L cj,.* a k i a
j 07 Orgrinic Onerni@-,try--Thevretic.41 orga!Ac chemintry
T':M. I RZXh1-m,j No* 5 1960,, NO. 1772,7
A ij III Of
C?.Tn MR,
i'ADS17@ACT
ABS. JOUR. I RZKhia.s Not 5 19601 NO# 17726
TITU.
MM.
ABSIRACIT f of C02 [sic], from which the authors conclude
that the reactidn I --vIl proceeds aa an Intermale-
,,,tjlrj.r rei@ction with the pArticipation of the CO,
Uroispht@ra. It im hypotheatzed that the reaction
17erin.nwith the lonization of I to Kive a carb-inio
011) .0th an -orshared pair of electrons Ln + @Jv@
or-rho-PoLAtion to the carboxyl grokip and K ; V
re,trrangcs into thi@ more stabl.e _,3ori,@r Witt, an
unni,,,Ared electran pair in the parq-ponition M,
which rubeequently adds C02 tind 11 + to give IT.-
f'AM
I R-Itus!'Y' J. and. -Sorm, F.
I !,'OL riven
t On the Nechunisri @,f the Rearrajigement of Potausium
Phthalate and of "he f'.9rboxyl-Jion of Potan!'111ir
Benzoate
I 1@ollectlon, Czec@oslov Chem Coninun,, z4, lio F31 29156-
No 1@, ?528-2335
"1./1,9 (1959); @-qe:n Listy, 5?,
9 Th,@ neck,.asism of the rearran.-4-,nent of K phthalato
1) to F terephthalate and of the cirboxviation
of F benzoate (11. 1) wiUi tho formation of 11 ir3r,
been ir.-.ostiFated. The rearranrL,@-Aimt cf .1 unier
-in nt@,,os,.,nere of '1140, glvas active It. The heat-
-ingr of I with 1140, to the reaction temperature
in the absence@of the catalyst or with the catalyst
but at i) lower temp;@rature does not Kive active. 11,
11 labeled with C14 4.n
the carboxyl group practi-
cally does riot lower the activity in an-@atmosphera
jr,

CATSG(BY
I
'AB9, Jam, RMdm&# NO# 51960p NO*
V35 IPA CT j--, zipparently initiated by the ioniZation of
Ill wit'@, the fotmatior, of K% C0j, jnd the anion
Cji4 which undergot-E. an exchange reaction with
Cz Hf, and V. The Lv t I., @r 4 !@, f,jr tha-.r con-
IT
in an atmcjsphcrt@
J. Kcv@r
4/,
(J.

LABLER, L.; SORM, 7.
Steroide.niv. ?A 1&dihydro2y-5*pr@gnan1-20-on@ (18-20 cyclo-
hemiketal) from nolarrhimine. In Inglish. oll.Cz.Chem. 24 no.9:
2975-2985 S '59. (nAI 9 '- 5 )
1. Department of Natural Products, Institute of Chemistry, Czechos-
lovak Academy of Science, Pregue.
(Steroids) Oihydroxypregaanone) (Holarrhimins)

KELOUN, B.; HOLEYSOVSKY. V.; VANICCEK, J.; KNIL. B.; SORM, T.
Proteins. LIII. Paptides of aspartic acid and glumatic acid Isolated
from a chymotrypsinogen hydrolyeate. In ftlish. Coll.Cz.Chem. 24
no-9:3002-3006 S 159. (MUI 9:5)
1. Department of Biochemistry, Chemical Institute, Czechoslovak
Academy of Science, Prague.
(Proteins) (Peptides) (Aspartle acid) (Glutamic acid)
(Chymotrypoinogen)

YAJKOS, J.; SORM, T.
Storolds XXXIX. Xplmoorle 2- and li-brozo derivatives of androstan-3-
one. In ftlish. Coll.Cz.Chem. 21s no.9t)115--)135 3 159.
(Ml 915)
1. Department of Natural P@roducts, Institute of Ghemistry, Czachcoloyak
Acadenq of Science, Prague.
(Steroids) (Adrostanone) (Bromine)

VAHCEK, J.; KEIL, B.; MMLOUN, B.; SORM, F.
Proteins LIT. Isolation of some peptides from tryptic hydrolyeates
of,chymotrypsinogen and diisopropylphosphoryltrypoin. In English.
Coll.Cz.Chem. 24 no.ge-3148-3153 S 159. (33AI 9:5)
1. Department of Biochemistry, Czechoslovak Academy of Science,
Prague.
(PROTEINS) (PMIIXS) (CHTMOTRTPSINOGIN)
(TRTPSIN DIISOPROM PROSPHATI)

GUT, J.; MORAVEK, J.; PARKANTI, C.; SKODA, J.; SORK, F.
Nucleic-acid components and their analogues. III. Antimicrobial
effect of some pyrimidine analogyes and related compounds. In
Anglish. Coll.Cz.Ghem. 24 no-9:3154-3162 S 159. OMAI 9:5)
1. Department of Organic Synthesis and Department of Biochemistry,
Institute of Chemistry, Czechoslovak AcadenV of Science, Prague.
2. Institute for Research, Production and Utilization of Radioiso-
topes, Prague (for Moravek).
Oncleic acid#) (Pyrimidine)

RTCHLIK, I.; BKRANKOVA, Z.; SORM, F,
The Influence of some physiologically active substances on In vitro
enzyme synthesis in mouse pancreas. In Anglish. Coll.Cx.Chem. 24
no-9:3163-3168 S 159. (XUI 90)
1. Department of Biochemistry, Czaahoslovak Academy of Science,
Prague.
WZYMAS) (PANCRFAS)

SORM, F.
Proteins, LV. Identical and analogous tripaptide atructures In
proteins. In English. Coll.Cz.Ghe-. 24 no-9:3169-)179 S 159.
(Y-UI 9:5)
1. Institute of Chemistry, Czechoslovak Acnden7 of Science,
P@rague.
(Proteins) (Peptides)

SIGHER, J.; RAJSInM, M.; RUDINGIR. J.; ECKSTMIN, M.; BORK, 7.
Amino acids and peptides. XXVIII. Synthesis of threo- and erythro-
dl.,V,e-diamino-@-hydroxybutyric acid (-r-aminothroonine and r-axlno-
allc threonine). In Inglish. Coll.0s.Chem. 24 to-11:3?19-3729 N 159.
(IUI 9:5)
1. Department of Organic Synthesis, Institut of Chemistry, Czechos-
lo-7ak Academy of Science, Prague. 2. On leave of absence from the Medi-
cal Academy, Xrakow, Poland (for Baketsin).
(Amino acids) (Peptides) (Allothreculne) (Amino group)
(Threonins)

HOLUB, M.; HEROUT, V.; HORAK, M.; ___?. - - -
!@@x
Terpens. 017. The constitution of betulenols from oil from the buds
of white b1rch. (Betula alba, L.) In ftlieb. Coll.Cz.Chem. 24 no.lls
3730-3738 N 159. (UAI 9.5)
1. Department of Natural Products, Institute of Chemistry, Czechos-
lovak Academy of Science, Prague.
(Terpetes) (Betulinol) (Birch)

HOLUB,M.; HEROUT,,V.; SORK.Y.
On plant substances. VIII. Analysis of substances extracted from
the root@ of a Werpitins lattfolius L, 11, Identification of
3,4-methylonedioxy-5-nothoyqproplophanone In the roots of
Laserpitium latifollus L. Coll Cs chem 25 no.12:)926-3937 '59,
(MUI 9:6)
1. Abteilung fur Naturstoffe, Chemisches Institut Techecho-
slovakishce Akademis der Wiseenschaften, Prag.
(Laserpitium latifolium) (Propiophenone),
(Methylene group) (Nethoxy group)

VRK0C,J,; MOUT,V.-, SORM,Y.
On plant substances. X. lsolati,,.@L -.1. crystalline parts of the
evelasting sand Helichrysum arenarium MCH. Coll Cz chem 25 to.
12:3938-3954 159. (F-RAI 9:6)
1. Abtelljng fur Naturstoffe, Chemischas Inatitut, Tachscho-
alova@ische Akademie der Wiseenschaften, Prag.
(Helichryoum arenarium)

IABIJM.L.; SCRK,Y.; GXW,V.
Steroids. nVI. Partial synthesis of 3.3.20-trimetboxy-18620-
epoxy-5 o(-- pregnane from dib7droholarrhialne. nVII. Partial
synthesis of la-benzoylamino-5 -pre&mane-3 -01P-20-ane from
coneasine. Coll Cz chem 25 no.12:4010-W21 159. (1UI 9:6)
Depart'sent of Natural Products,, Institute of Coemistry,
Czechoslovak Ac@dsl'w of Science, Prague.
(Steroids) (Metho37 group) (Holarrhimine)
(1po3wregnans) (Amino group) (Prognanons)
(Conessine) (Sen20Y1 group)

BORK, F.; SKODA, J.
Antimetabolites of nucleic acids as carcinostatic substances, Cae, lek*s
ceak. 98 no.28:868-873 10 JulY 59.
1. Biochemicke oddeleni Chemicky ustav, CeekoslovenakR akzkdemis ved,
Praha, prednosta akademik Yr. Sorm. F.S., Praha 6, Na evicisti. 2.
J.S., Praha 12, Ritranska 7.
(OTTOTOXIC DRUG6, eff.
6-azauracil, bacteriol. & carcinostatic properties (Cz))
(URAGIL, antag.
same)

KONIG, J.; MOM, Zd.; SKOIWL, J.; SH&HRL, 0.; 503M, Yr.; SV3HIA, Ct.
Prospects of development in the chemotherapy of malignant tuxors in
CzachoBlovakia. Cas. lek. cesk. 98 no.28:877 10 July 59.
1. Interni katedra Untava pro dookolovani lekarn v Naze, prednosta doc,
dr. 0. Smahel, Bioahemicke oddeleni Chemickeho ustava CSAV v Praze,
T)rednouta akndemik Yr. Sorm. J. K., Praha-Krc, Budejovickft 800.
(ITSOPIASMS, ther.
chemother., progr. in Czech. (Cz))
(GH3MOTXWP'T, in various dis.
cancer. progr. in Czech. (Cs))

Identity of jatsmansone and valerspone.
kpln*#.
Herout. and F. Aorm (Cxechn-sMYaTMd.S8' p9m).
r.-7r-q Mtbij LOM17W. No. 3. 9-12; cf. CA 53, 3M.-
Comparison of ploys. cmists. of derivs. and of degradation
roducts proved the Identity of &Kviled jawnansone
ovindachari, et al., CA $4, 4657f) and voleranone
M
(Stoll, d al.. CA 52. 4550e). Redo. of U with
valeranol, Cnths(). do 1-M46, xV l.UW. JaIV 611.4*
(CHCh). dehydrated with P.C#HACOW at :r7a.-WO to
valerene, CoHn, do 0.904.'t. MY DOW', hydrogenated
with rereduced Pt(]@ to valeane. Ckil", do OSM' %V
1.4M, also obtained by treatment of Il ethylenethloketal
with Raney N1 In dimane. The phys. coasts. of U, t6
0.9712. M? 1.4944 jaj'V -43.0% m.ps. of semkorbasone,
205-7'. oxime, 113-14 . and 2.4-dinitropheny[hydrazone,
99-1000. were very similar to the corresponding values
0.9623, IA88, -40.1% 206.8% 112% and 1OL* recorded
forl. Ozonfutiono(UmanobettzytWenededy.,m.101-2*,
and cyclization of the dicarboxylic acid, CI&HxOl (III). M.
236-7% with Ils(OH)v save the cyclic norvaleranone, q,-
H,40, P 1738 cm. -I (semicarbuone m. 238-40*), @onverted
to a liquid monobensylidene deriv. and ozonized to not-
ic " (IV). C14H*04. m. 143'. dehydrated by py
valeran
rolysis or on treatment with AcaO to the cryst. anhydride:
Ct,HnOo (V), m. 77-8 0, brominated to a cryst.
hydride (VI). in. 14"'. Quant. bromination showed that
a me@ lene grou and a quaternary C atom were adjuent
to the 40 group & U. Dehydropuation of valeranol with
S at 190* 4 hrs. or Se at 28D-3W' I hr. or of valerene 1.5
firs. with 5 at 180* or 6 hr3. at 200-W* or 30 win. with W.
dine at 290' gave no detectable amt. of an aromatic derly.
of I te. Only 2 hrs. dehydrogenatim of valeranot
lb 50"i @",d-C at M-40' led to a mixt. a( atuleak hydro.
carboin. The degradation of I save products. m. 233-4'
.143*, 8"', and 143'. corresponding to III, IV, V. and VI:
A provisional formulation with it partial structurto
suggested. C. R.

JAKUBOVIC. A.: KEILGVA, H. ; SORM, F.
Certain properties of liver catalase inhibitors present in the
medium after tumor cell culture. Neoplasma.Bratisl. 7 no.1 suppl:
?1-75 l6o.
(NEOPLASKS)
(CATAIASE antag)
(TISSUE CULTURE)

KEIIDVA, H.; JAMMOVIC, A.; SORM, 7.
On Inhibition of the liver catalase activity. I. Influence of
media after cultivation of Nola btrain tuwizr cells on the
activity of liver catalase. Neoplassm,Bratial. 7 no-3:257-267 160.
1. Institute of Chemistry. Cxechoelovak Academy of Sciences,
Prague, C.S.S.H.
(LIVER ches)
(CATALASE chem)
(TISS" CULTURK)
(NEOPLASMS exper)

SMRT, J.; BERANEK, J.; SORM, F.
Nucleic-acid components " their analogies. IV. Synthesis of
.4 -d-ribofuranosyl-6-azauraell-51 phosphate and phyrophosphate.
Coll Cz Chen 25 no.1:1)0-137 Ja 160. (EUI 9:12)
1. Department of Organic Synthe3isq Institute of Chemistry,
Czechoslovak Academy of Science, Prague.
(Nucleic acids) (Phosphates) (Pyroph03phates)
(Ribof'uranosyltriazinedione)

LABLER, L.; SORM, F.
Steroids. XLIII. Partial synthesis of 18-hydroxyprogesterone from
holarrhimine. Coll Cz Chen 25 no.lt265-269 Ja 160. (EW 9:12)
1. Department of Natural Products, Institute of Chemistry,
Czechoslovak Academy of Science, Prague.
(Steroids) (Hydroxyprogesterone) (Holarrhimine)

VONASEK, F.; HEROUT, V.; SORM9 F.- I
Terpenes. CVII. The composition of essential oil from false cubebs
and the structure of cubeb camphor. Coll Cz chem 25 no-33919-926
mr o6o. (ERAI 9s12)
1. Department of Natural Productsp Institute of Chemistry,
Czechoslovak Academy of Science, Prague (for Herout and Sorm).
2. Aroma, Prague 2 (for Vonasek)
(Popper) (Terpenes)

KASAL, A.; CERNY, V.; SORM, F.
Steroids. XLIX. Preparation of methylester of 18-dimethylamino-
3-oxo-5oL-androstane-17#4 -carboxylic acid. Coll Cz chem 25 no-3:
927-933 Mr 160. (EEAI 9112)
1. Department of Natural Products, Institute of Chemistry,
Czechoslovak Academy of Science, Prague.
(Steroids)
(Eaters)
(Dimethylaninooxoandrostanecarboxylic acid)

JOSKA, J.; FAJKOS, J.; -SQT!@- F.
Steroids. L. Analogues of androgens with the B-nor3teroid skeleton.
Coll Cz Chem 25 no.4:1086-1090 Ap 160* (EUI 9;12)
1. Department of Natural Productsq Institute of Chemistrys
Czechoslovak AbaderW of Science, Prague.
(Steriods) (Androgens) (Norateroids)

MALUNOWICZ, I.; FA.TKOSj J.; SORMI F.
On steroids. Part 411 Epimeric 2-bromo and 4rubromo derivates of
cholestan-3-one. Coll Cz Chem 25 no.5-.13519-1370 My '60.
1. Department of Natural Products,, Institute of Chemistry,
Czechoslovak Academy of Sciences, Prague, 2, On leave of
absence from the "Wyzsza szkola rolnicza, Katedra. chemii
ogolnej," Wroclaw (for Malunowicz).

NOVOTNY, L.; 11LAOUT, F---
On terpenes. Part 109: A contribution to the structure of
absinthin and anabsinthin. Coll Cz Chem 25 no-5:1492-1499
My 160,
1. Department of Natural Products, Institute of Chemistry,
Czechoslovak Academy of Sciences, Prague.

IqOVOTNY, L.; ILEROUT, V.; SOM, F.
On terpenes. Part 3-10: A contribution to stereochemistry
of absinthin and artabsin. Coll Cz Chem 25 no.5:1500-1505
14Y 16o.
1. Department of Natural products., Institute of Chemistry,
Czechoslovak Academy of Sciences, Prague.

MOTLf 0.; WOUT, V.; SOM4, F.
Terpenes. CXII.The composition of the oil from Juniper ozycedrus L.
berries. Coll Cz Chem 25 no.6tl656-1661 Je 160.
(EEAI 10:9)
1. Department of Natural Products., Institute of Chemistryq Czechoslovak
AcaderW of Science, Prague,
(Terpenes) (Juniper)

MIKESP 0.; KAKOLp I.; ZBROZYNA, A. J.;.SORM, F.
Proteins. LVIII.Growth-stimulating peptides from neutral fraction
of a partial acid bydrolysate of obymotrypsinoges. LIX.Growtb-stimu-
lating peptides from neutral fraction of a partial acid hydrolynate
of diisopropylphoaphoryl trypoix. Coll Cz Chem 25 no.711938-1951
J1 160. (MI .1029)
1. Department of Biochemistry, Institute of Chemistry, Czechoslovak
Academy of Science, Prague(for Mikes and Sorm) 2. Present address:
Department of Biochemistry, Marcel Neacki Institute, Warsaw, Poland
(for Kakol) 3. Present addreas'. Department of Biochemistry,, State
Institute of Hygiene, Warsaw, Poland (for Zbrozyxa)
(Proteins) (PeptideB) Obynotrypsixoges)
(DileoprophIpboapboryltr7psix bydrOly2ateB)

DOWS) L.; SORM, F.
Terpenev. CXIII.Structure of aromdendrene, alloaromadendrens,'
globulol, ledol and virid1florol. Coll Cz Chen 25 no.731837-1843
JI 160. (RUI losq)
1. Departnient of Natural Products, Institute of Chemistry, Czechoslovak
Academy of Science, Prague.
(Terposes) (Aromadendrene) (Globulol) (ledol)
(Viridiflorol)

JOSKA, J.1 FAJKOS, J.; SORM, F.
Steroids. LI.Derivatives of 5A - and 511--b-norandrostane. Coll C2
Chem 25 no.9:2341-2357 S 160. (Kul 10:9)
1. Department of Natural Products, Institute of Chemistry,,, Czecho-
slovak Academy of Science, Prague.
(Steroids) (Norandrostane)

TOMASEK, V.; HOLEYSOVSKY, V.; MIKES, 0.; SORM, F.
Proteins. UII.Peptides isolated from peptic bydrolvaate of diinapro-
pylphoaphoryltrypain. Coll Cz Chem 25 no.9:2369-2375 S 160.
(EEAI 1039)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.
(Proteins) (Peptides) (TrMin) (Isopropyl group)

VANECEK, J.; MELOUN, B.; KOSTKA, V.; KEIL, B.; SORM, F.
Proteins. LXI.Peptldes isolated from peptic bydrolyeate of chymo-
try-painogen. Coll Cz Chem 25 no.9:2358-2368 S 160. (EKAI 10:9)
1. Institute of OrgaDic Chemistry and Biochemistr7 Czechoslovak
AcademW of Science, Prague.
(Proteins) (Peptidea) (Chynotrypoinogen)

CEKAN, Z.; PROCHAZKA, V.; HEROUT, V.; SORM, F.
Terpenes. CIV. Isolation of globicin, a guianolide from Matricaria
globifera (Thunb.) Druce.,Coll Cz chem 25 no.10,2553-2558 0 160.
(EEA1 10:9)
1. Research Institute for Natural Drugs, Prague (for Cekan and
Prochazka) 2. Department of Natural Products, Institute of Chemistry,
Czechoslovak AcadeuV of Science, Prague.(for Herout and Sorm)
(Terpenes) (Globicin) (Matricaria globifera)

BERANKOVA, Z.; RYCHLIK, I.; SORM, F.
Enzymic inactimtion of oxytocin. I. Selective inhibitors of oxytocin
inactivation. Coll Cz cbem, 25 no.10:2575-2580 0 160.
(EEAI 10:9)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Acadeny of Science, Prague.
(Oxytocins)

SUCHY, M.; HERCUT, V.; SORM, F.
Terpenes. CXVI. Structure of cynaropicrin. Coll Cz Chem 25 no.11:
2777-2782 N t6o. (EEAI 10:6)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science* Prague.
(Terpene3) (Cynaropierin)

GRUNBERGER, D.; CERNA, J.; SORM, F.
Intracellular peptides of Escherichia coli. Coll Cz Chem 25 no.11:
2800-2806 N 160. (EEAI 10:6)
1. Institute of Organic Chemistry and Biochemistr7, Czechoslovak
AcadevW of Science, Prague.
(Peptides) (Eacherichia coli)

CERNYj Vs; SCRMO F,
Steroids. LII. Preparation and acme reactions of 18-amino-3d)-
pregnane-3,4 g2O� -diol. Coll Cz Chem 25 no.11:2841-2848 N 060.
(ELU 10: 6)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.
(Steroids) (Amino group) (Pregnanediol)

KASAL, A.; CERNY, V.; SORM, F.
--- - -------------------
Steroids. LIII. 18-benzoylaminoproge3terone and a-,me of its
reactions. Coll Cz Chem 25 no.11:2849-2854 N l6o. (EW 10W
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.
(Steroids) (Benzoyl group) (Amino group)
(Progesterone) .

LABLER, L.;,SORM, F.
Steroids. LIV. Some derivatives of (200-315 020@-dihydroxypregn-5-
en-18--oic acid (18-20) lactone. Coll Cz Chem 25 no.llt2855-2862
N o6o. (EEAI MO
1. Institute of Organic Chemistry and Biochemistry Czechoslovak
Academy of Science, Prague.
(Steroids) (Lactones)
(Dihydroyyprognenoic acid)

KARADZOVA, M.; KEIL, B.; SORM, F.
V-
Peptides isolated from acid hydrolysate of edestin. Coll Cz Chem 25
no.11:2878-2888 N 160. (EW 10:6)
1. Institute of Organic Chemistry and Biochemistryq Czechoslovak
Academy of Science, Prague.
(Peptides) (Edestin)

SORMCVA, Z.; MELICHAR, 0.; SORM, F.
Some pyrimidine derivatives as new types of plant stimulants. Coll
Cz Chem 25 no.11:2889-2898 N 96o. (EW 10:6)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.
(FYrimidine) (Plants)

SEBESTA, K.; BAUEROVA, J.; 6OM,-F.,--SQRMOVA, Z.
Transformations of uracil analogues in cucumber seedlings Coll Cz
Chem 25 no.11:2899-2905 N 160. iEEA1 lOs6)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.
(Uracil) (Cucumbers)

M
BAUEROVA, J.), SEBESTA, K.; SORM9 Fa; SORMCVA, Z.
The effect of uracil analogues on the metabolism of pyrimidines in
cucumber seedlings. Coll Cz Chen 25 no.11:2906-2912 N 6o.
(EEAI io.-6)
1. Institute of Chemistry and Biochemistry, Czechoslovak AcaderW of
Science, Prague.
(Uracil) (Pyrimidine) (Cucumbers)

5/081/62/000/023/108/120
B101/B186
AUTHORS: Ratusk Josef, Sorm, Frantisek, Ulbert, Karel
y
TITLE: Method of producing organic substances having the properties
of electric semiconductors
PERIODICAL: Referativnyy zhurnal.- Khimiya, no. 23, 1962, 742,.abstract
23P476 (Czechool. pat. 100972,. September 15, 1961)
TEXT: Polymeric organic substances of the semiconductor type are obtained
by thermal decomposition of inorganic salts of acetylene carboxylic or
polyacetylene carboxylic acids, followed by separation from the inorganio
salt by boiling with inorganic acids, or by leaching out with water and
using the carbonate dissolved in filtrate*to neutralize the acetylene
carboxylic acid Ahen producing the initial monomer. Example: 50-5 9
anhydrous powdery acetylene dicarboxylic K (1), obtained by neutralizing
the acetylene dicarboxylic acid, is heated to 265 - 295 0C. The resulting
mass is cooled, pulverized, leached out with water, and filtered; after
drying in air, 5.19 g powder is obtained, the conductivity of which is
Card 112

S/081/62/000/023/108/120
Method of prolucing organic ... B1OI/BI86
0-7-10- 4 ohm- 1. cm-1at 200C, and!1.4-10-2 ohm- 1. Cm-Iat 300 0C. The
, . filtrate in tined for producing 1. When 5% by 0weight of CdCl2is used as
catalyst, I thermally decomposes at 385 - 400 C. IAbstracterfs note:
Complete translation..
j
Card 2/2

K,'"v%A, V.; MUSSIL, J.; IiOVT-'NY7 A.; PADOVLC, J.; S04!, F.
Chemoth!@rapy witii 6-azuuraGil in gynaecology. Acta univ. carol.
(mod.) 7 no.5:617-633 '61.
1. Klinika chorob zonskych a porodnictvi lakar3ke fakulty hygionicko
University Karlovy v Praze, vedouci doe. MUDr. J. Padovec Ustav
organicko chor-io a bioc' omie CSAV, prednosta akademik F. Som
Biochamicko oddolani falmitni nemocnice v Praze 10, primar MUDr.
WlDr. J. Oppit.
(GENITALIA ROULE neoplasms) (URACIL antagonist,s)
(AfiTII,'-','OP;ASTIC AGITTS ther)

JAKUBOVIC, A.; KICILOVA, H.; SORM. Y.
On inhibition of liver catalase activity - II. The influence of
cell-free ascitic fluid on liver catalase activity in mice.
Heoplasma,Bratial.8 no.1:45-51 161.
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Sciences. Prague, Czechoslovakia.
(LIVER metab)
(CATALASE metab)
(NEOPLASMS exper)

SORMOVA, Z.; S013M, F.
Anomalous course of thermal denaturation of deoxyribonueleic acids at
leukemic and irradiated animals. Neoplacm 8 no.6:619-,620 161.
(DESOXYRIBONUCLEIC, ACID chem)
(IMKENIA exper)
(RALDIATION INJURY exper)

DULLOS, L.;MLYI'L, 0.; SOUGM, M.; HEWUT, V@; @'-
On terpenes. Part 108: Epineric aromendendranes. Stersoisomerism
of ledol, viridifluorol and lobulol. Coll Cz Chem 25 no.5:VX3-
1491 MY 161.
1. Department of Natural products,, Institute of Chemistry,
Czechoslovak Academy of Sciences, Prague.

JAROLIM, V.; STREIBL, M.; HEM, K.; SORM, F.
Composition of lignite. I. Some substances present in montan wax.
II. Additional substances present in montan wax. Coll Cz chem 26
no.2:459-465 F 161. (Ew 10:9)
1. Institut fur organische Chemie und Biochemie, Tschechoslowakische
Akademie der Wissenschaftenp Prag.
(Lignite), (Montan wax)

--SORMY F.; KEIL, B.; VLNECEK, J.; TOMASEK, V.; MIKES, 0.; MELOUN, B.;
KOSTKA, V.; HOLEYSOVSKY, V.
Proteins. LXIII.Lower structures in the chains of proteins. Coll Cz
chem 26 no,2:531-578 F 161, (EEAI 10:9)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
IAcademy of Science, Prague.
(Proteins)

SYKORAY V.[deceased]; NOVOTNY, L.; HOLUB, M.; HEROUT, V.; P@RMI F,
The proof of structure of carotol and daucol. Coll Cz Chem 26 no-31
788-802 Mr 161. (MAI 10: 9)
1. Institute of Organic Chemistry and Biochemiatry, Czechoslovak
AcademV of Science, Prague. t
(Garrote) (Carotol)

SOUCEK, M.; HEROUT, V.;__@ORM, F.
Terpenes. CIVIII. Constitution of parthenolide. Coll Cz Chem 26
no.3:8U-810 Mr 161. (EEA1 10:9)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.
(Chrysantemam parthenium) (Terpenes)

DOLEJS, L.; HEROUT, V.; SOM4,
Terpenea. CXX. Sesquiterpenic compounds of Baccharis genistellvidin
Fera. Structure of paluotrol. Coll Cz Chem 26 no.3.-811-817 *r 14A.
(EKAI 10:9)
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.
(Baccharia genistelloides) (Terpenes)
(sesquiterpenes) (Falustrol)

GUTP J.; PRYSTAS, M.; JONAS, J.; SOM4, F.
Nucleic acid component4i and their analogues4 Part 9: N-%wtb71 deri-
vateo of 6-asauracil and 6-azathymine. Coll'Cz Chem 26 no.4:974-985
Ap 161.
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Sciences, Prague.
(Nucleic acids) (Methyl) (Azauracil)
(Azathymine)

DOLEJS IL.1 MIRONOVI A.; SORMt F.
On terpenes. Part 1211 Structure of bulnemol and otersochosistr7
of guaiol., nspetalic acids and iridomyrascins. Coll Cs Chem 26
no.411015-1020 Ap 161.
1. Institute of Organic Chemistry and Biochemiotryp Czechoslovak
Acadenq of Sciences, Prague (for Dolsjs and So:Z 2. Moscow Institute
of Light Organic Technology, Moscow (for Mirosov
(Terpenes) (Essences and essential oils)

VRK6e, T.-;'1MOUT, V.--j - SOHN, F.
On terpenes. Part 122: Composition of sequiterpenic ketonic fraction
of sweet flag oil. Coll Cz Chem 26 no-4t1021-1025 Ap 161.
1. Institute of Organic Chemistry and Biochemistr7o Czeeboslovak
Acadeny of Sciences, Prague.
(Terpenes) (Essences and essential oils)

MIMS, 0.; HOIZSOVSKY, V.; TOMASEK, V.; SORM, F.
On proteins. Part 64: The structure of peptides isolated from peptic
bydrolysate of dilBopropylphosphoryl-trypBin, Coll Cz Chem 26 no.4t
1048-1064 Ap '61.
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Sciences, Prague.
(Proteins) (Peptides) (Trypsin)

- SORMP F.
On proteins. Part 65, Some regularities in the structure of ribo-
nuclease. Coll Cz Chem 26 no.4:1174-3-179 AP 161.
1, Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Sciences, Pragud.
(Proteins) (Ribonualease)

SOWN.
On proteins. Part 66: Resemblances in primary, protein structure.
Coll Cz Chem 26 no.4:1180-1186 Ap 161.
1, Institute of Organic Chemistr7 and Biochemistry, Czechoslovak
Academy of Sciences, Prague.
(Proteins)

CERNA, J.; GRUNDBERGER, D.; SORM, F.
Nucleotide peptides in Escherichia con. Coll Cz Chem 26 no.4:
1212-1214 Ap 161.
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Sciences, Pmgue.
(Peptides)

JOSKA, J.; FATKOS, J.; SORM, F.
--------------
On steroids. LVIII.Sone analogues of androgens substituted in posi-
tion 7. Coll Cz chem 26 no.6: 1646-1657 -16 161.
1. Institute of Organic Chemintr@r and Biochemistry, Czechoslovak
Academy of Science.
(Androgens)

BERANKOVA, Z.; RYCHLIK, I.; SOR@j Tt
Razymic inactivation of oiUUcin. II.Fission of now peptide frag-
ments of the oxytocin structure and their derivatives by pregnancr
serum and liver call eap. Coll Cz chem 26 no.6:1708-1715 Xe 161.
1. Institute of Organic Chemistry and Bio-Zhemistry, Czechoslovak
Academy of Science, Prague.
(Peptides) (Oxytocin)

HOCHKANNOVA, J.; HEROUT, V.;-_@qH& F.
On terpenes. Part 127: Isolation and structure of seequiterpenio
lactones from common yarrow (Achillea millefolium L.). Coll Cz, Chem
26 no.7:1826-1831 Jl 161.
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Sciencesp Prague.
(Terpenes) (Lactones)

BENESOVA, V.; HEROUT, V.; '@O-RMJ-Lt-
.
328: The existence of oi'- -and 16 -bumalene. con
On terpenes. Part
Cz Chem 26 no.7:1832-1838 Jl 161.
1. Institute of Organic Chemistry and Biochemistry, Csochoslovak
Academy of Sciences, Prague.
(Terpenev) (Huzalene)

JOSKA, J.; ACHREM, A.A.j FAJKOS, J.; SORM, F
On steroids. Pat#t 61: Some B-nor steroid hormone analogues. Coll
Cz Chem 26 no.8:2050-2057 161.
1. Institute of Organic Chemistry and Biochemistryp Czechoslovak
Academy of Sciencost Prague, 2. On leave of absence from the
Institute of Organic Chemistry, Academy of Sciencep Moncow, USSR.
(for Achrem).

FROCIIAZKA, Z.; FAJKOS, J.; JOSKA, J.; SORM, F.
On steroids. Part 60: Microbial oxygenation of B-nor steroids.
Coll Cz Chem 26 no.8:2068-2U71 161.
1. Institute of Organic Chemistry and Biochemistryt Czechoslovak
Academy of Sciencesp Prague.

NOVAK, J.J@K,; FAJWSj J@'-Aqim' F,-_
Relationship between chemical structure and insecticidal action
in the series of pyrethroide substances. Part 5: A synthesis of
trans-2., 2-4ichloro-.3-phenyleyclorpropane-carboxylic acid and its
allylrethronyl ester. Coll Cz Chem 26 no.8:2090-2092 161.
1. Institut of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Sciences2 Prague.

5URNAMEP Given Name3
Countrys Czechoslovak
Academic Degreess Lnot given
7
Institute of Organic Chemistry and Biochemistry, Czecho-
Affiliations alovak Acadovq of Soiencesq Prague
sources Praw" 0) WAMMMI
Vol Z6, go 10v October 61, pp Z496-2510
Datas "Amino-Acids and Peptides. XXV, Analogues of
OV,tocin Modified in Positions 1 and 2 of the
Peptide Chain% Protected Intermediates."
Authors:
JOST, K
RUDDIGER, J
SOMI, F

SUFITAMEp Given Names
Country: Czechoslovakia
Academic Degrees: [not given]
Institute of Organic.-Chemistry and.DiochemistrY.
Affiliations Czech6s-loiij@Acadomy of Soiencest Pragu--O'---- @
Sources Prague, CoUection of Czechoslovak Chemical Commudcations,
Vol 26, No 10, October 1961. pp 2551-2536
Datat "On Terpenes. CXXX. Isolation of Digerarql and Isodigeranyl
from Bergamot Oil."
Authors:
SOUCEK, M
@IHEROUT, V
SORM , F

HUME, Given Names
dountr:tt Czechoslovakia
Academic Degrees: Cnot giveqV
Affiliations Institute of Organic Cpq4qgy-and--Bio-Chq14#@9
Czechoslovak Acaderq of Sciences, Prague
Sources Prague, Collection of Czechoslovak Chemical Coununication-s-
Vol 26, No 10, October 1961, PP 2557-2W
Datat "Enzymic Inactivation of Oxytooin, III, Desthioo)Wtocin
and S,S'-Dibenzy1di1Wdrooxytoc!Ln as 0)Wtocinase
Inhibitors and Substrates,"
Authors:
BERANKOVA. Z
SOMI, F

HEROUT, V.; SUCHY, M.; -SORK, F.
On terpenes. Part 131: Isolation and structure of costunolide, balchano-
lide, iaobalobanolide and bydroxybalebanolide, moquiterpenic lactones
of germacrane type from Artemisia balchanorum, H. Krasch. Coll Cz Chem
26 no,10:2612-2623 0 161.
1. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Scienceo Prague.

SUFUIAMEp Ui-ven Names
Countrys Czechoslovakia
Academia Degreest Cnot given7
Institute-of organic Chemistry wd Bioaherdstrys
Affiliation i Czechoslovak Acadww of sciences. Prague
80"ce I pru"It 1,011061"a Ole GlObB0,1144 Ahni a
Vol, Z60 No lot ooww 1901t pp zhy--zw#z
Datas P&n7RU Loctivation of OVUO" IV . Characterization
of Purified P mtions of SWM 0MUCIMSO."
Authors-.
CIRAR, M
BMMOVA, Z
RrCF=, I
SOM, F

ZADRAZIL, S.; SORMOVA, Z.; SOFM, F-
Separation of nucleic acid components on Sephadex. Coll Cz Chem 26
no.10:2643-2650 0 161.
:L. Institute of Organic Chemistry and Biochemistry, Czechoslovak
Academy of Science, Prague.

3URNAME, Giv( Namds
Countrys Czechoslovakia
Acadeaic Degreest [not given]
Institute of Organic Chemistry and Biochemistry~
Affillations Czechoslovak Acadeaq of Sciencesp Prague
Source I Prague. C"W"Map op W&MInak M44wl PmenM&Mmf
Vol go, no 190 0010DW 19619 pp ZM-W5
Datat "Iril-Abition of the U 3-Contract-Ang Effect of
Owtooln by O-M*tkW1oVtocin.G
Authors:
BERANKOVA,
RYCHLIK, I
JOST, X
RUMMER, J
SORM, F

VRKOC, J.; HEROUT, V.; SORM, F.
.1-- .-
On terpenes. Part 133: Structure of acorenonep a sesquiter-
penic ketone form sweet-flag oil (Acorus calamus L.) Coll Cz
Chem 26 no.12:3183-3135 D 161.
1. Institute of Organic Chemistry and Biochemistry, Czecho-
slovak Academy of Science, Prague.

-S0Aj,_Frantisek, a1mdemik; MASTOVSKY, Otakar; KASPAR, Janj SIRACKY, Andrej;
VjUFA-,-Tosef; ZACHOVAL, Ladislav; RASKA, Karel; BLASKOVIC, Dionyz,
akademik; WICHTERLE, Otto, akademik; PRANTL, Ferdinand; CUTA, Frantisek;
JERIE, Jan; HEIMR, Kamil, akadeiiik; CAPEK, Ladislay; LINK, Frantiseki
STRUD, Julius
Report on the activities of the Czechoslovak Academy of Sciences made
at its 12th General As#emblyjand the discussion. VtBtnik CSAV 70 nool:
26-34 161.
1. Namestek presidents. Ceskoslovenska akademie ved (for Som).
2. Clen korespondent Ceskoslovenske akademie ved (for Hastovskyj
Kaspar, Siracky, Vana, Zachoval, Raska, Prantl, Cuta, Jerie,
Capek, Link and Strnad). a.' Predseda SloVenskej akddemie vied
(for Siracky).

SHQf@4, F._ISOIUI, F.), akademik; CHEMMKIY, V.P.; KHIADM, S. [HLADEK, S-33
VESELAY, Y.; SMRT, Y.
6-Azacytidine andita derivativea. I;okl.AN SSSR 137 no.6:139,3-
1395 AP 161. (MIRA 24:4)
1, Institut organicheskoy khimii i biokhimii AN Chakhoslovatzkoy SSR,
Fraga (for aU except Chemptakiy). 2. Institut organicheskoy khimli
Akadendi nauk USSR, Kiyev (for chernetakiy).
(Azacytidine)

S/058/62/ooo/ol2/033/048
A1601AI01
AUTHORS: Kell, B.., florm,
TITLE: On proteins. LXXI. An analysis of protein structures from the
aspect of amino acid interchanges
PERIODICAL: Referativnyy zhurnal, Fi;lka, no. 12, 1962, 36 - 37, abstract 12D26D
("Collect. Czechosl. Chem. Communs", no. 5, 1962,v.27, 1310 - 1319,
English; summary In Russian)
TEXT: The series of amino acids is compared to various porteins to find
the 3ymmetry or a similarity In the arrangement ofamino acids along the poly-
peptide chain by taking into consideration a possible substitution of one amino
acid by another. By using the methcd of symbols, A*was shown that the symmetry,
principle occurs rather frequently in the arrangement of amino acids. For r1bo-
nuclease and C cytochrome it was discovered that a definite series type Is most
frequently found, i.e., a major part of the protein is built from several main
series. This Is particularly clearly apparent in the case of o(-- and A-chains
of hemoglobin. Part 70 see ref. 12D259.
rAbstracter's note: Complete translation]
Card 1/1

,--F- -
F.
The effect of 6-azauracil,, riboside against vaccinia. virun in
rabbits. Acta virol. 6 no.3-282 My 162.
1. Research Institute of Antibiotics, Roztoky near Prague, and Institute
of Organic Chemistry and Biochemistry, Czechoslovak Acaddmy of Sciences,
Prague @IPJCLEOSIDES AND NUCLh;OTID4S pharrracol) (VACCINIA exper)