SCIENTIFIC ABSTRACT WETZLER, I. - WEYROCH, J.

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CIA-RDP86-00513R001961520019-7
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December 31, 1967
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SCIENTIFIC ABSTRACT
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HO,Z,A, Frantisek, inz.; WETZLER, Pavel, inz. A complex study of boring technology development. Geol pruzkum 6 no.9:262-263 S 164. 1. Central Geological Office, Prmgue; State Commission for Development and CoordinatLon of S3ience and Technology, Prague. ME= f 11-MORSK.I. Stefan, dr in3. `cat Economizing --teel in the '"ght, of requirere3rts of i,-,n rules.. Bud okretowe Warsvvia 10 no.3.,79, innart A,B-(;,tj Mr 165. 1. Gdansk Technical Unluvernity, -ICERHA MEDICA Sec 18 Vol 3/6 Cardiovascular June 59 1423. Malignant hypertension NadcisnienieZIO',IiAVCSZCZEICLIKL. III Klin.Chorob Wcu-ne-trznych A. 31., Wroclaw lViad. lek. M8, I VA 1-12 (493-501) Graphi 2 After an introduction concerning the pathology of so-called malignant hypertension, tile author give!; details of 30 personal cases. The "vssential" form of malignant hypertension was found in 18 patients, the remaining 12 showing the "secondary" malignant hypertension during c-r subsequent to a nephropathy. rhe. author finally gives some therapeutical examp~.es, and states that a simultaneous administration of hypotensive drugs is advantageous. A distinct remission of all clinical symptoms (including optiad symptoms) was found only in 3 cases, The improvement was 0 bs, d 2 years after therapy. (XVIII, G-) e~v~, -A CNRIU, A.,; VOINISCU, M.'; SIMICIM. I.,; 01MIU. I..; V_W-Mt B.,; ANGMLESCU, I.,; RADULISCU, D.,; BUNESCU, G.0; W2ftkkT-z2~R-:--; LAURI", S. Preparation of substances inhibiting the development of bacterial resistance during therapy of tuberculosis and active In therapy of leprosy. Stud. corcet. inframidrobiol.. Bucur. 6no.1-2sl87L197 Jan-June 55. 1. Institutul Prof. Dr. Is Cantacusino, Sectia do chimloterapie, Bucuresti. (TUMMOULOSIS, therap)r diaminodiphenyl sulfone deriv.,prop. & value in inhib. of beat. resist.) (T-PPROSY. therapy diaminodiphonyl sulfone deriv., prop.) (SULPOIAS, therapeutic use diaminodiphanyl sulfone deriv., in leprosy & tuberc.) OMIU, S..; VOINNSCU, M.,; LUPIJ, A,; MItT. I.,; VXXLXFL, B11 Study of derivatly's of 4immilcotinic acid lWdraside. 1. is.onicatinoylbydrasone derirativei of ketone &ctds. Dal. stijnt.L sect.' nod. .7 no.2.657~-563 Al)r-june. 55 1. Moubm corespondent &I A(ademisi M. (for Oeriu) (HTDWIlJM,* derivatives isonicotinoy1hychuzono deriv. of ketone acids, chem. study (MrIM ACIDS same) WHERE =ms= I Country cato-t-.;ry Abs. icur Author instit,ut. Tltla- Orlr~ Pub. 1.;'ibstract I Card: RUMANIP. Organic: Chemistry. Synthetic: Organic Chemistryl Ref Zhw M%JZ-, No 5, 1959, No. 15357 Oierlu, S.; Voineseu, M.; Wexler, B.; Gloter,El I Synthe.-iis of Some Asymetrically Substituted 1 Thioureas with Potential Tuberculostatic Acti-I vity Report I Studli si cereetari chim.,, :L958, 6, Nc) I.,p 155-16o With the purpose of investigating the tubercu-1 lostat~ -c activity (TA), 4-ROC 6H4MCSNHCH2CH= ' C112 (I i (where ~ R =C,31 (E) 02 R5-0 CH2 =CHGH2f f a) CA, S 04H9, (D iso-G4H99 (1) G8H 109 and 4- C2H50Cj~14'NHCSNHR (II) (where R=3,4-diraethyl- isoxazolyl--2) were synthesized. Synthesis of I is aeacmplished by boiling 4-ROC6"4. NH2 (III) with CJ12=CHCH2NGS (IV) in GH 3OH. I, quanti- tie a o,!.k origiinal III IV in g, and CH30H in v1. 1/3 Couratry G lAbs. Jour Ref Zhur Xhim., ft 5, 1959, No. 15357 lAuthor I List Itut. Tltl Orl- Pub. 0 0. (from alco-! ,yield of I in mp. of I In hol) are given: Q 5, 7, 5, 77, 79; 0 26, i49 100o 60t 9Z;(Z 20, 10, 70, 54, 74 (from aqueoun alcohol); W15, 8.7, 50p 60, 66; ~ 6.5, 3 23,40, ft-85;- 0 9 5.2, 30~ 55.5- 105-10~? S 3, 1-5, 10, 70, 66-67. Analogous'ly, from,7 g. 4-C2H50COOGS and 7.3 9. of 3,4-dimethyl- 5-aminoisoxazol in 7 ml. of CH OH II Is ob- tained,yield 40%, M-p- 171-1720 ifrom alco- hol). TA (in relation to 3trains H 37Rv and H. 2/3 Country G f Abs. Jclar Ref Zhur Maim., No 5) 19~9) so. 15357 A lluthar 0, TA1 Ori,~-; ?ub. Lbstract in dilutions of 1:180,000 :Ratti) eb.anges with cont'd. and.1:1,800,000. TA of JI develops In a dilu- tion of 1:10,000,000.-- V. Skorodumov Card.- 3/3 -G 31 RUM-IIA Organic Chemistry. Synthetic Organic G Cheadstry. Zhurimj K11imiya, No. 15, 1958, No. 50312 Abs Jour Ref. Author Arventiev, B..; Strul Millexier, H.,, Cahane, D. Inst Title Preparation and Study of Some Aryl Thioureas - IV Oxy and mathoxy- naphthyl Thioureas. Orig Pub Studil si cercetarl Stunt. Acad. RPR Fil. Iasi. Chim. 1956, T, JL1, 24-30. 7r Abstract Oxy-, methoxy and carboxymethoxy derivatives of -naphthyl thiourea (I) were synthesized. The toxicity of the prepared substances was studied. Heating the solution of 1-amino-2 naphthol- chlorohydrate (II) vilth KH4NCs(III) in glaclal CH3000H (IV) yielded 2-oxy-I (V). By analogy 4-oxy-1 (VI) was obtained from 1-amino-4-naphthol chlorohydrate (VII) and,III. Methylation of V Card 1/4 RU W Ik Organic Chemistry. Synthetic Organic Chemistry. Aba Jour Ref. Zhur. Khimiya'~ No. 15, 1958p No. 50312 in order to obtain 2-mothoxy-I (VIII) led to a formation of a previously syntheal."Ied 2-amino, nWDhthoxyazole (IX). The latter compound may L e also prepared by interaction of V and CrOH2- COOH in an alkaline medium and by heatinS of al- coholic solution of V with HgO. 4-methowy chlorohydrate M or 2-methoxy-l-naphthylamine chlorohydrate when reacted with III or IV yielded, correspondingly, 4-methoxy-1 (XII) and VIII. Reaction between III, 1-amino-4 naphthoxy acetate (XIII) and IV yielded 1-thiouretedine-4 naphthoxy acetate (XIV), While reaction between .o