ORIG. RUSSIAN: EFFECTS OF EXPOSURE TO SMALL DOSES OF RADIOACTIVE SUBSTANCES IN CHRONIC EXPER.

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP88-00904R000100130002-5
• Release Decision: RIPPUB
• Original Classification: U
• Document Page Count: 45
• Document Creation Date: December 22, 2016
• Document Release Date: August 31, 2009
• Sequence Number: 2
• Content Type: STUDY

 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
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Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
 Approved For Release 2009/08/31 : CIA-RDP88-00904R000100130002-5
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 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
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Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
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 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
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Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
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a Talc:.-,e HOBO Odpa3oBaHHble HepBHbie BOn0IOHL);a C Bblpal eHHbIMY, peaKTNB-
HHMI1 cIB.ueHziiMM (nOBwuellHasi apreHTOCI)Y1nwi ). C TeueHNeM Bpelremi
y1JaCTItiI1 110906HOI TlcaH14 yBen14t1LMBaJOTCn, a rrepec'ipoi1 Ka IOCTHb1X CTpyK-
TVp ycnnNLiaeTr'I. PaccacbInaeTCn IcaK CTapasi KOCTb, Tai 11 BO3HMIcluasl
B TetleHLie 3adOneBaHl4n. 11apa;lnenbH0 0dpa3yeTCA He3penasi 06bI3BeCT-
BneHHaFi 11 HeO6LI3BeCTBneHHaSI KOCTb 14 KOnnareH. Tax14M o6paJoi.1,no-
CTeneHHO g00PLIMpy10TCFI otiarbi naTOnor14lecxor, IcOCTN c yclueHHo ee
nepeCTpciiEOr . IIoAo6Hue U13iieHeHYIA MOT B AanbHeiiweM 3aKaHti1BaTbCSI
pa3JMT3reMM: onyxonL1. PenTreHOnorI ecx1, no ,gauHbiM P.N.?1axapbltieBOI1,
naTOnorIr ecxee icocTeodpa3oBaHNe onpe)JensieTCSI B BJ4 yyacTIOB doJree
RROTHOi'I KOCTHOii CTpylcTyphl C HenpaB14JIbHO pacnono cen1mlM1 rpydbJmIrr,
ypOAJILIBbHIMII4 IOCTHbIM11 TpaOelcynaMl4 B CnOHrUO3HOM Cnoe KOCTYI.
C TetieumeM BpeMeirn Icon1geCTB0 xneTOx OCTeoreHHOi TKaHI Bce
donee yBeJII4t1I4BaeTCn, npM 4CM cpeA14 HI4X npeodna,U,aIOT CBOciO.1IH0 uexautze
pa3Hoo0pa3HorO BNAa 14 pa3MepOB KneTic. OCTeoreHHa1 TKaHb, 000TOSI-
luasi X13 no,il;o6Hblx KJIeTOK, o6pa3y eT IIpOJIImcl)epaTbI, OTn1tlaloiuie..c$I c ioxcHo-
CTbIO CT9OeHI4n Irr pacnpocTpaFSrlou.14ecsl BHyTPX KOCTHO-MO3rOBOr4 nOJIOCTY1
C pa3pyllleHi4eM npeAcylueCTBy10u~14X ROCTHbIX CTpyrcTyp (pl4c.22 ). IloAo6Hhre
143MeH1eHMSI MoryT dbITb pac eHeHLI icai npeAonyxoneBble Nii KaK Hatlanb-
Hble OnyXOneBble. PeHTreHOnorneclc1 B MecTaX IIaTOnOrl4tiecfcor0 xOCTeo0-
pa3OBaHI4H BWIBJISIIOTCSI 43MM1eHEHi4 i odlueii CTpyKTypbl aTI4IU1tIHOYI IcOCTX C
4Ctie3HOBeH1eM t1aCTM danop. 14 HOIBJIeHY1eM HoBblx.
3aTer.i Becbr;sa cxopo cpeA14 cxoIlneH1Yi He3penblx, aTIlnM4Hux ocTeo-
? Approved For Release 2009/08/31 : CIA-RDP88-00904R000100130002-5
 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
-25-
Approved For Release 2009/08/31 : CIA-RDP88-00904R000100130002-5
reHHbix KJIeTOK, IIOSIBJIRIOTCf1 61ICTpo yBenvrtlr;salon 1ecR y3enEx (pic .23),
KOTopwe, paCnpoCTpaH$ 1Cb BH3TpN KOCTIio-Mo3rOBOli nOJIOCTN,pa.3pywalOT
KOCTHbI1I M03I' N ICOCTb, a 3aTeM IJWXOASIT 3a npe).reJIL1 I opi4KaJIbHoro
CJIOA KOCTN. flo,I1;o6Hble GI3MeHeHi4n CBHAeTCJIbCTliy10T 0 pa3B14TNI4 onyxoJIUI.
Hatiairo 3noKat4eCTJ3eHHOro pOCTa xopoillo onpe)J,eJISJeTCR N peHTreHOJIoriJ-
,iecKN. flpiT paabvIT014 npeNr1rytueCTBeHH0 OCTeornJlacTNlJemix Onyxoile1
nor'IBJI1eTCSI ynJIOTHeHLIe IcOCTN, IcOTOpOe y13eJiU4tijBaeTCR B pa31.,iepax;
npvr pa3brTNN npei4 yl.ecTI3eLiHO oCTe0JMT14t1eCKYJx onyxoJIeii npeo6JlaAanT
SIBJIeR44sI pa3pyweHr4 J ICOCTN (yi3e:INtleuxe oiaarori pa3pe,ii(eHMs1 XOCTHO>i
TKan).
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OTHOCSJTCSI K TaK Ha3bIBaeMWiri OCTeonJIaCTI't1eCKIIIJ OIIyx0JinnM (oCTeodiiac-
TocapicoMa, OCTeo 1AcapIcoMa, OCTeocl epoTMtiecKasr caploMa), pese -
CMewaHHbIM NJUQ npeMMyneCTBeIIHO OCTe0JINT14geCKIiM (noJlNLiop4JoHoxji.eTOtI-
HBA, zpyrnoKJleTotluaR capxoMa). BCTpetlaIOTCS1 C N6pocap1OMN N ocTeo-
XOHApocapKoMli. IIocneAHNe o6JraAaloT 06hIgH0 OCTeJINTJrJtlecI iib CBOYCTBa-
MN.
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350 AHeii nocjre BBeAeH 1 pa,Il;NoaITNBHoro Beu(eCTBa B onTJiJMa1:bHbix
6JIacToMoreHHNx A03ax, Y KpOJI'n oB - uepe3 20-20 MecRueB, y codai
uepe3 2-6 JieT. OnTNl'IaJIbHLIe 6JIaCToMoreHHbie A0311 Ana pa3Hb1X BZAOB
ICMBOTHbIX N pa3JINtIHbIX 143JIytJaTeJleii He OANHaKOBbI. ]3 HaN6onbrueM npo-
t eHTe ony xojiN pa3BNBa10TCR y Oemix xpbJc (,go 70-80,",2' OT odtuero KoJrN-
tIeCTDa OrLITHUX i.-MBOTHbzX), npNtiem y 60nbiuei ziaCTN ;:I-1BOTHIJX BO3HN-
KaeT OAHoBpeMeuxo HecIOJIbHo onyxoJI J3bJX y31IoB. 0006eHH0 tiaCTO Ony-
XOJIYr pa3nMBaI0TCR B AJINHHblX TpyOtiaTbIx I'OCTSIX, a TaK'r e D 1103BOH014HZ-
Ke. McTacTa3vrpyJ0T OnyXOJIN BO BHyrpeHHNe opraHLI, n0 cepo3HbIM noxpo-
BaM 14 B JILI1vi(JaTNtIeCKNe y3JILI.
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OCHOBHOM cxo,leH. KOCTHaR TxaHL KpbJc, Mbrlueli x KpoJINKob oOJla.naeT
6onbluo1 pea1TNBnnoCTbio N ee YJ3MeHeHNSi y 3T14X BNAOB LIBOTHHX npo-
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Y Kpbic x muweii IIMeeT McCTO donee 6LIc Tpoe pa3BI;,TNe OCTeoreHHok,
TKaHm c 06pa3OBaHIfieM He3pe)lok np4M14TTIBHOk KOCTN, tJeM / co6aK.
Y KpbrC, MbiDe1l N KpOJINKOB KOCTHaSI TKaub paccacbinaeTCB rnaBHbJM o6-
pa3olw NO TNny OCTeOKJracTLStlecr.oI-l pe3op6L1N, TorAa Kai y co6aK
I1MeeT rdecTO na3yurasl pe3op6Lj7R.
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0oJlbfUee KOn14'4eCTBO onyxo ie1I y,gaeTCH noJiytlaTb y deJI x Kpbic,KOTopue
paCTYT donbWylo LIaCTb }KH3HH. EcJIN ?Ke paANOaKTHBHOe BeUjeCTBO Dona-
,uaeT BO B3pOCJIbdi OpraHH3M, TO HMeeT McCTO 60JIee paBHOMepHoe, HO
McHee Bupa>KeHHoe nopaxeHY1e cKeneTa.
Kai H3BeC THO, pa3JWlHble H3OTODbl TaK Ha3bIBaeMO'I "KOCT H0 !" rpyn-
nbI He BnOJIHe OAHOp,O,f HO pacnpeAennX)TCa B CaMOI KOC TH. HanpHMep,
P-H3JIytlalouw2 CTPOHL1 k HaKafJIHBaeTC$I no npeHMyUjeCTBy B 3OHaX
3HXOHApaJIbHOro OKOCTeHeHHFI, r,ge z NMeeT McCTO OCOdeHHO 3Ha 1HTeJb-
HaS BacIyn,qpI3auwli H r,ue Haudouee NHTeHCHBHbI o McHHble npoL(eccbl. OA-
Han TOT ?ite CTPOHuH17I, BBeAeHHbN I }ICNBOTHOMy (codaKe) C 3aIOHt!eHHNM
pOCTOM KOCTek B AJIHHy, pacnpe,genNeTCH donee paBHoMepHo. ,U,pyrHe,
3neMeHTbl ( j3 -H3nytlalouMg HTTpM17[, a -H3JIyt1aI0ll HLI nnyTOHH9 ), En
H3BeCTHO, pacripeAenAroTCB B cxeneTe donee paBHoMepxo, C HKCNpygcb
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ce HaKannNBaeTCH B HaI donbmeM KOJINL1eCTBe TaM, rAe NMeeT McCTO POCT
KOCTH W,CneAOBaTeJIbHO, rAe OdMeHHMe npoueccN KOCTHOI TKaHN donee
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BeUgeCTB B cIe.IeTe, MbI He CMOr)H OTMBTHTb cyUjeCTBeHHOkI pa3HHtjbU B
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Bb13uIBaIOT Oo iee rnydoKHe N3MeHeHH,9 cIeneTa. HpM ;)TOM L1eM goJlbme npo-
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Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
BaeMLJM AoJIr0; 1ByI. mjj4 3JIeMeHTaM11, O,uHaICO B gwlbHeliiwem no xo,11y tr)Ii-
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Approved For Release 2009/08/31 : CIA-RDP88-00904R000100130002-5
 Approved For Release 2009/08/31: CIA-RDP88-00904R000100130002-5
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