SCIENTIFIC ABSTRACT YUNUSOV, S. - YUNUSOV, S. YU.

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• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001963120020-7
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: March 15, 2001
• Sequence Number: 20
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

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non!.~tho A!kalolds of Plantu of the Favily Papfivorac~-as. Vi. T:.,) Alkn_lolds of, th-
GLnbrilliFenuqn, Zhur., Ob.-;hc)-... 9~ No. 21, 1939. Alhaloil Dupi;.
AU~-Ubioli SoCI.-R=. DuAco-PhanmcAti C-al inst. Ivoni S.
Reculvea li..Juno 1,052.
9. 4W-Report. U_ 1626., 11 ~iin 1952

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URIMOV, U. 1. -YUMSO R demik, otvetstvemWy redaktor;
lYMEGHA'AMTA',T.'X..r9i~ktor izdatelletva; SHMLIKOV, A.T.,
takhnicbeski7 re4ktor
[An unimown woA by.al-Razi, 'The Book of the Secret of Secrets,*)
Neizvestnoe sochiramis ar,~-Rzzi 'Eniga tainy tain." Tashkent, lzd-vo
Akad.usuk Uzbekskoi SSR9 1957. 190,p. (MIRA 10:11)
1. Akademlya nzi* Uz3SR (for Yunusov)
(Mubammad lbu Zakiri7a,.Abu Zakr, &I-Razi, 10th Cant.)
(Alcheni)

f.-

YUMOV, S.Yu.,akadsmik; PIMIMOVA, N.V.
--Sir
-2
Study of TrIebodessma Inamn= alknloldo. X)okl.AN Uz, SSR r0.
4:31-33 '57. (MMA 11:5)
1. Inatitut khimli rastitelinykh veshchestv AN UzSSR.
2. AN USSSR.
(Alkaloids)

el
~t~

USSR Cultivated Plants. Medicinal. Essential Oil- M-7
Bearing. Toxins.
Abs Jour Ref Zhur Biologiya, Be 2, 1959, No. 6478
'
Author :'Yunusov, S.
Yix.; Plekhanova, N. V.

Inst A of
*;7111M&Myr.~ ~~-enceo UzSSR
Title Study of Alkal6lds in Sophora Griffithil
Stock
Orig Pub Dokl. AN UZSSR,-1957, No 8, 17-19
Alkaloids derived-from the leaves and Beed8
-of B. griffithil.Voro isolated. The content
of alkaloids In leaves (-4.65%) was
approximately thesame.during the fruit
bearing stageand after the fall of fruits;
1.6% of pachybarpino and 0.57% of cytisine
were obtained by separating the alkaloids.
5.93% of the alkaloids wero Isolated from
Card 1/2
159

,____~USSR
Bearing.. Toxins.
Abs Jour Ref Zhur - Biologiya,,No 20 1959, No. 6478
seeds. 4.12% of cytisine were obtained by
separating these alkaloids. Tho method of
extraction of tho alkaloids, their separation
and Identification are described. .1. .1.
Zaytseva
Card 2/2
/.Cultivated Plants. Medicinal. Essential Oil- M-7

t~;
F..*.'i,,-I,-, ,
'y ~!, Z - I I .

A11THORSs Yunusov. S. I A.Muazimov, Kh. A. 79-12-36/43
TITLE: An Investigation of the Four Types of Alkaloids From Ungarnia
(Issiedovaniye alkaloidov chetyrekh vidov Ungernia).
'PERIODICAL: Zhurnal Obshchey Khimii 1957, Vol. 27, Nr 12, Pp. 3357-3361
(USSR)
ABSTRACT: The alkaloids-of the plant.species Ungernia were subject to
few chemical and pharmacological investigations. Only the
tazettine was separated from the species "Ungernia Severtzovii"
and the'llikorine7l from "Ungernia tadshicorum" . On the in-
vestigation of the first species a production rate of
0,7 - 0,29 % of alkaloid from the bulbs was established. It
was succeeded, to isolate three crystalline radicals from the
alkaloid mixtdre of the bulbs. One of these forms a series of
crystalline salts A free alkaloid was seperated from the
purified chlorine hydrate. An empiric formula C19H2311'05 of
this alkaloid was computed on the basis of an elementary ana-
lysis of the radicalitself as well as of its nitrate. It
was called ungerine. After the removal of the ungerine from
the remaining alkaloid mixture the already mentioned tazettine
was separated on the basis of their different solubility in
Card 1/2 acetone and.alcohol. The third alkaloid from "Ungernia

-An Investigation of the Pout Types of Alkaloids From Ungernia 79-12-36/43
Severtzovii" appeared to be new and was called ungeridine.
It has the experim'ental formula C20H25 N04 and its structure
was determined-moreexactly-(see formula!). It appears, that
two new alkaloids were obtained apart from tazettine and
likorine from "Ungernia Severtzovii". From the bulbs of
"Ungernia tadshicorum" likorine and ungeridine were isolated,
from the bulbs of "Ungernia Victoria" galamantine and likorine,
The bulbs of"Ungernia ferganicall contain tazettine and likorine.
These alkaloids were all four eamined pharmacologically by
Mushkovakiy M. D. There are 8 references, 8 of which are
Slavic.
ASSOCIATION:' 'Institutc; of VegeUble Rav Hateriale, and
Cottcn. Chemistry (Institut khimii i rastitellnogo syr1ya i
khlopka)
SUBMITTED: August 2i, 1956
AVAILABLE: Library of Congress
1. Alkaloids Sources
Card 2/2

xs;, SID%Mxt Gol~,,; 7mwvsj~~*. akmdenlk~
Of UPIOI)'A7l3zm follov= Vr&do; foUosidtw, Zbk:L, All
U*. SSR -w*-5:23-26 ~10. (xm ntB)
MoV

Alkaloids of Haplopbyllum follaosum Vved. Structure of dnbinidine.
Dokl, AN Us. SSE vo*8t?7-29 158, (MIRA 11:9)
l'Inatitut ihimll raefltellnyM veshcheetv AN
UzSSR. 2.AH UzSSR
(for Tutusov).
(Dabinidins)

TUMMOV, S.Tu.,akadeislk; SULMOV, IT.T. - PMW&NOTA, N.V.
Alkaloids fro"s ConTolva-as. subbirautus l4d. arA *hme of the
famI17 Convolvulueau.. Tok.~ANX;.= no-10:17-20 158,
(mm il: 12)
I* Inatitut ii rastitel'mykh veshchestv AN Uz&M#2, Chlen-
ko.rrespondent*,,AN 330 1 akadmik AN UzEM (for TIMUSOV).
(A oids) (33indweed)

PWKWOVA, Nev.
Alkaloids from Rindera cyclodonta Dip. from the Boraginaceae
fAM117, DckI.AN Uz,MR- ro, 12:27-30 - 158. (RM 12: 1)
2. Institut Wmil rastitellnykh veshchestv AU UzSSR- 2..tN UzSSR i
eblen-ko-.7aspondent .0 SM (for Y=usov).
.(Asia, cantial-Sora&) (Alkaloids)

IDTAKINO G.P..;BBSSONOVA, I.A.;YUNUSOV. S.Yu.
Allmlol& of seeft of Haploohyl lum perforatum: Perfor In. Dokl.
AN Uz.SSR 116-101-33-35 159 (Hla 13:3)
1. lustitut khinii 'rastitelim7kbveshchestv AF U265R. 2. Chlen-
korrespondent AN'SSSR (for Tunusov).
Ok

Yanusov.-S. Yub and kekhanova, 11, 1. SOV/79-29-2-66/71
-.TITLEs Alkaloids of the Plant Trichodesma Incanum (Alkaloidy Trichodesma
incanum)
Struoture of Incanine and Trichodesmine (-Stroyeniye inkanina i
trikhodesmina).

PERIODICAL:-
pp 677-684 (USSR)
Zhurnal obshchby khimii, 1959, Vol 29) Hr 2
ABSTRACT: Men shikov, G. P. and Bubinshteyn, X. M. (Ref 1) separated the
alkaloid trichodesmine.(00075 %) from the subterranean parts of
the above plant. By lengthy extraction with ether and chloroform
the authors obtained from its seeds various mixtures consisting of
bases (Ref 5)- On separating the alkaloid mixture (from ripe seeds)
four crystalline bases were separated by making use of their differ-
ent solubility in ether, benzene and acetone. The first alkaloid was
unknown and was given the name of "incanine" M; the second was
the N-oxide form of-incanine; the third was foand to be trichodes-
mine (11), and the fourth was the'B-oxide form of trichode8mine.
Both the quantitative and qualitative composition of the alkaloids
in the seeds vary markedly depending on the degree of ripenose, on
the place of growth, and as far as the subterranean parts are concem-
Card 1/3 ed, on the plant developing stage (Table). Thus the following new

SOV/79-29-2-66/71
...AlkaloidB of the Plant Trichodesma Incanumo Structure of Incanine and Tricbc--
desmine
alkaloids were aeparated from the seeds and the upper part of the
H
0
plant Trichodesma incanum, (Bge)DO: incanine (C
n)' the N-ox'de
l.,
27
5
---of-incanine, trichodeamine (C; 18E2
061R), and the K-oxide of trichodes-
7
mine. Depending on the type of eaponification of incanine, new
geometrical acids are formeds incanine acid and icoinconine
from the comuosition, 0 R (V). The conversion of the former into
10 1604

the latter and vice versa was put into practice. The reduction of
the methyl esters of both acids with UAIH trioxy compounds
4 gave
having the composition 0 1E 0 (111).,Compounds (V) are r-lactono
6 22 3
of 2-0'Y-3,5-dimetbylhex"e-2t4-dicarbonic acid (IV). Incanine (I)
has the structure of the cyclic diester of retronecine and of 2-oxy-
-3,5-dimothylhexane-2,4-dicarboni-o acid. The structure of tricho-
desmine acid (VII), Which AY, an
.Is a .1--tonic acid of 293-dioxy-3,5-di-
A
methylhexane-29,4-dicarbonic ac
(VI), ras determined. Trichodewaine
is a cyclic diester of retronecine:and of 2,3-diqxY-3,5-dimonthy1-
hexane-294-dicarbonie acid (11)., There are 1 table and 10 referencea,
Card 2/3 8 of which axe Soviet.

m

5W.,
Tunnsor, S. Tu., Abdua-Zimov, Kh. Ao
AUTHORS: SOT/79-29-5-67/75
TITtEr Investigation of the Alkaloids of Vngernia Severtzovii
(Issledurvaidys alkaloidov Ungernia Severtzovii).
Structure-ofTngerine" (Stroyeniye ungerina)
PERIODICALt, Zhurnal obBbehey khimlip 1959, VPI 29p N.- 5P PP-1724-1728
(USSR)
-ABSTRACT: On diatM-lng~"Ungerlno" with-~zinc dust the authors obtained
phenanthridinol amd.in the oxidation with potausi-am peTmanganate
they obtaihea hydrastic acid. In the Hofmann decomposition-a
second double bond is forned in the tetrahydro benzene ring B,
and a thira by cleaving the methoxyl group as methyl alcohol;
the ring is thus aTOMati2ed. This was established bry the faut
that benzDic acid was obtained in the oxidation orf' dva-H--mvttrr1
"Ungerinel-~ 'Ungerine" is a derivative of phonanth-rittrre, -tyr -
which the -methylene dioxy group is in position 6-~;-The doubie
bond Iles most probably between the carbon stoma 1 2, the
nethoxyl group in position 3.
Card -1/2

5-.3900 77414
SOV/79-30-1-75/T8
iUTHOM.. Sldyakin, 0. P., leskairov, M., Yunusov, S. Yu.
TITLE:. Alkaloids of the Ha
pl3phyllum Foliosum Vved.
-
Structure of Dubinidine
PERIODICALi Zhurnallobshchey khimii, i966, Vol 30, Nr 1, PP 338-
345 (USSR)
-ABSTRAM is a-continuation of the investigation of the
This
l
enus Haplophyllwn A, Ju3s. (family Rutaceae)
Yunusov, S. YU -. Sidyakin, 0. P., Zhur. Ob3hchey
~
Xhim., 22, 1055 (1,952); 25, 2009 (19535); D_)Iclady
-Akad. - Nauk, UzSSR, -12, 15 - (1950) ). The aut horLi
.
studied the-alkaloids of the specieo' Haplophyllum
foliosum, Vved. (from its stem, leave3, and green
seeds). Four alkalqids were isolated: dubinidine
(which was first obtained from Haplophyllwn d-iblum
Eng. Kor. -- see the reference cited above),
skimmianine, and two new alkaloids called by the
Card 1/8 authors "foliosine" (foliozin) (Doklady Akad. Nauk

'Alkaloids.of the HaplophylDum Foliosuim Vved. 77414
Structure of Dubinidine SOV/-[9-30-:L-755/T8
UzS9R, 2, 21 19
'0
H and "foliosidine "(foliozidin)
(ibid., 5, 23
95 . Dabinidine was precipitated
f:rom aqueous Bolution of the alkaloids (this solution
was obtained by tj~eating the chloroforin extracts of
H. fol-iosum withoulfuric.acid) with gaseous NH 3'
The preCiDitate was dissolved in acetone md converted
intothe hydrochloride (mP 195-1960, [a]
(-53.920)).

Pure dubinidine lip 132-1330,
[CLI D
26.5
(-62-950)) was
,
obtained by addition of concentrated NHI,,OH to
aqueous suspension of its hydrochloride. Its ultra-
violet.spectrum is shown in the figure below, along
with spectrum of dihydroflindersine (which has a
pyranoquinoline structure.).

Card 2/8 --------- --

M
n
I

Alkaloids of the HaplophYlil-un FuIlooum 771114
Vved. Structure of Bubinidine SOV/79-30-1-75/78
F11111.11'e, 0- ra v I o It,
ab,,;orption upectra, (1)
-dine; (2) dihyd~,o-
roine; 4-metiioxy-
flinde
quinoline-2.
4.4 -
02 -
J40
;L np
Card 3/8

Alkaloids of the Haplophyllum, Folloaum 77414
Vved. Structure of Dubinidine SOV/79-30-11-75/78
'Die following derivatives of.dubinidine were
prepared and investigated:_ hydrobromide(mp 197-.1980);
8
hydrolodide (mp 161-i6:20, ECL] ' (-47.320)); nitrate
I D
(MP i~6-1770 , ECLI "- (-52-390)); methiodide mp 153-
1540 which, uponDaddition of-alcoholic alkali, gave
isodubinidine, compound (II) in the figure above (mp
214-2150, ECtj 25 (+2.1.-050)); diacetyld-.ibinidine (mp
D
108-1090, EA1 19 P17 .700)). Oxidation with YJ4.1011
led to-an aldehyde and then to the optically in-
active dictamnini.p.acid.(III In the figure above).
Skimmianine was separated from the other two
obtained from the
chloroform extracts of the aolution which was left
rafter precipitation of dubinidine by triturating
-themixture in.acetone, which disso.' -ves fOliO3ine
and foliosidine),The-mixture of the two latter com-
Card 5/8. -pounds was purified by subsequent addition of 10%

Alkaloids of the Haplophyllum Follosum 774114
Vved. Structure of Dibinidine SOV/79-30-1-75/T8
HC1 and axrLwonia -and extraction with chlorofo.,Tr,
.(followed by distillation of the latter). The
residue was dissolved in methanol and:acidified
with alcoholic HC1. The optically inactive foliosine
hydrochloride ~np 253-2540) fell out after addition
of threefold amount of acetone to the cooled solution
and waa converted 0to foliouine by addition of 2-%
NHL,,OH (mp 188-189 ). Tne following fullosine "'
deMvatives were prepared: hydrobromide ~ip 249-250o
(decomp.)); hydroiodide (mp 225-2260 (decomp.
nitrate (mp 170-171-50 (decomp.)); methiodide
210-2110); and perchlorate (mp 229-2310 (decomp.)).
Its formulawas found to be: C HlOP(NCH ) (CH 0
15 3 2 2)'
The alkaloid residue Isolated from the acetone
solution, which was left after precipitation of
f 0. lios-Ine, contained- mainly: T olir idine, C1 H ~O5 N-
T 2
mp 1 __25 (+4 1,620 'Its more de ailed
141- 420 and ECLI D
Card 6/6 -formula was- found to be C H 0
15 15 2 (NCH3 )(OCH 3)(OH)2'

A2kaloids,of.the Haplophyllum Foliosum 77414
Vved. Structure of Dabinidine SOVIT9-30-1-75178
The ultraviolet spectrum (in alcohol) has the
f ollowln$ maxima: 234 (log 4.94); 252
(log E, 4.92); 324 (!Wt', 3.98); 234 m 4 (log E
3. 84) Abstraeter'8 Notes Two maxima max 234 are
given In the article, The following deEivatives:
were prepared: hydr8bromide (mp 167-168 ); hydro-
chloride (mp 162-164 ); foliosidine picrate (mp
.182-1830); and diacetylfoliosidine (mp 129:-1300
[CL] 18 +.14.~50)). There is I figure; and 14 ref-
D
erences, 7 Soviet, 5 German, I U.K., and 1 U.S. The
U.S. and U.K.,'references.are: G. Sidney, A. F. Smith,
-E. C. Horning,.J. Am. Chem. Soc. 79,, 2239 (1957);
R. P. C. Brown, J. J. 'Hoobs, L. K. Huges, E. Ritchie,
Austral. J. Chem., 7, 4, 348 (1954).
ASSOCIATION: Institute of Chemistry of Plant Substance3) A-cademy
Card 7/8 of Science,s of the UzbekSSR (Institut khimii rastitell

-A2kaloids of the Haplophyllim Foliosum 77414
..-.:Vied. Structure.of Dubinidine SOV/79-30-1-75/78
nykh,.veshchestv Akademii nauk Uzbek-3koy SSR)
SUMITTED: October 29, 1958

.3L 10, 5.3900 779'8
AUTHORS: Yunuzov, S. Yu. Akramov, S. T.
TITLE: Investigation or Alkcaloid,~ 01' 1,01111M. QUIlUatUill.
Commullicatlon 11.
PERIODICAL:- Zhurnal obshchey _16ilmill ic)6o, Vol 3)(), 141-2,
pp 6y'(-68,,2 (ussa)
j., tg,-'-
ABSTRACT: The aUthon', reported pvc-viou:_;J,~
Q
Vol 25, 1) 1813) tlv~ sufjarutJon or 3' -li-vi
-a Ilift
Vroul ti 1,011um (au"u
Gramineac), which they IlLuno'd 1011.111dill (1), .101.1.11
_(II), and lolinLn (III).
.100(>N-. -N1
C
7 11 \COCII
(10
It was also established (Izv. AN.UzSSR, ser. Ichim.,
.1957, Vol 2, p 69)-that dichloroethane condenses
Card:1/5 readily. with alkaloids containing primary and

investigation of' Alkaloids of' Lol-ilum 7 7 9.181
~ - '7
Cuneatum. Communication II. SOV/79-30-2-6--,/
secondary 11itro'Pen atoril-'i in Lhe moRc0c, and thfij.
C,
it forl-no type (IV) oi, ~V) c(;rjipoundz;
can form also type (VI) or (VII compoill-,C].--, on
densation with otronc, tert-lary bases.
NN-) N/ C711100I(>N-)(011)
\COC16)
M
M e i; I i y I a t I c, nof V111 with formaldchyde and Lormic
acid In 1:2:2 molar ratio gave N-methyllol-ln
(,(IV -Ulfurlc "Ic'j-d (2
whIch viltn K11nO,,1 anrl:
0), wu; O)Adlzled t.'-) IT; oxidul-LO11 111
(0 -atopio W p~ave VIII..
ell
(XIV)

--investigatiah of Alkaloids of Loliurn
77918
CuPeatum -.CQmmunication 11, 0 11/7 9 - 3 0 - 2 - 6
Lolin-II .was oxidized to VIII with Kfln04 in sulfuric
acid, There are 7 Soviet references.
-ASSOCIATION: Chemical Institu te-f or pl.ant Substances, Academy of
SCieliceo or the Uzpbok SSR ('rtj~jtjtkjt raot1te1'nyk'ii
~Voshcheotv Akademil nauk,Uzbekskoy SSR)
,SUBMITTED:, February 25, .1959
.,Card 5/5

77919
SOV/19-30-2-7O/T8
AUTHORS: -Yunu.sov,,�, Yu., Akramov, S. T.
TITLE: Inveetigation of Alkaloids of Lolium Cuneatum, Communi-
cation III
PERIODICALs Zhurnal obahchey khImii, 1960, Vol 30, Nr 2, PP 683-689
(USSR)
ABSTRACT., Norlolin (1), lolin (II.), and lolinin (III) have a
common heterocyclic ring; this has been demonstrated in
the preceding study by the mutual conversion of one of
the above alkaloids into another (our abstract 77918).
N/) -N
11711100 -No( -.N