SCIENTIFIC ABSTRACT SERGEYEVA, T.I. - SERGEYEVA, V.F.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001548120006-4
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: August 23, 2000
• Sequence Number: 6
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

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L-38636-65

AGCESSION NR: AP501137
6

10 MM161 A 21~_, w
(for Mice)., Treatmia vi
i-perfring'ens-type-A--brought' h4j- I r jaww lbe.'2 at
1 dayw
Tn. this case there vas~dbserved a :tYpical: anaer6ble _A~ Ws after food.
Poisoning-:caused by:Cl*-- -t-M A -
perfr1ilge1w --which -4~ Vwy- rare- occurrence

in medical practice.-.--
- -
Vi_a4t,_:,o
ce ld woman-'V" str 610
in the- cond: 6-1 sita-49-
a
I .
ing,after eating roast duck --and. pastry. - Mie -dieC41ti in: 10 btiurs. cul-
iuies of samples taken from thii~, liver an&: siall intest Was revealed a I

*-mi isms- Cif _tfii oil
-grow
croorgan
morphology characteristic for
.
,
Thii-adtftitrAl. --ths*
-Biochemical-tests also- confiriWd, --this*.
8:MLD/ml_and 4 MW/61,for the-4amples- fr;am the liver: 434. Aftestlws- re-
spect1wily.
Institut epidemiblogi :4
ASSOCIATION: AMN_ SSSR;.-(

of Epidemiology and Micro iold AMN 'SSSR).
b gui
suBmiTTED: 29mar63--
NO ITEF SOV-.. 002

cc
rd

ACCESSION NR: AP4009077 S/0016/64/O0O/OO;/OlOI/bIO8
AUTHOR: Ivanova, L. G.; Sergeyeval T. I,-
TITLE: Changes In the nitrogenous composition of broili made from the dry KPD pre.
paration during growth of Clostridium botulinum types A, 8, C aii~ E
SOURCE: Zhurnal mikrobiologil, epidemlologii I Immuncibiologil, no. 1, 1964, 101-
108
TOPIC TAGS: botulism, Clostridium botullnum, botulln production, Clostridium
botulinum metabolism, Clostridium botulinum nitrogen metabolism
ABSTRACT: -In order to provide information as to the nUtritive requirements of
Clostridium botulinum, required both for diagnostic put-poses and to Improve the
production of botulin, the authors determined the total, protein and amino nitro-
gen, peptone and tryptophan, as well as the amino acid composition, In a broth
prepared from the dry KPD formula (described by Ivanovit et al., Lab. delo, 1962,
No. 4, P. 33), before and after 5 days' growth of Cl. totulinum types A, B, C and
E. Biological assays of the amount of toxin produced yielded values of 20-50
thousand Dim/ml for the Memphis strain of type A and the Nevin strain of type B,
compared to 50-100 thousand Dim/ml for strains No. 98 of tgpe A, 175 of type B
and 91 type C, and only 10,000 DIm/ml for strain No. 18 -20 of type E after
Card f12

ACCESSION NR: AP4009077
Inactivation with pancreatin. Chemical analyses showed that the amino nitrogen
content increased 3-fold during growth of types A and B, 2-fold during growth of
type C and. 1.5-fold with type E; the peptone levels were inversely proportional to
the amino nitrogen levels, as was the concentration of tryptophan, which com-
pletely disappeared during growth of types A and B, decreased 50% during growth of
type C and remained essentially unchanged with type E. Chromatographic studies of
the amino acid composition of the medium showed that many amino acids take part in
growth and toxin production. The levels of glycine, threonine, and glutamic and
aspartic acid increased sharply during growth of types A, B and E, but remained
unchanged with type C, while serine, arginine, lysine, histidine and some others
decreased or disappeared. In contrast, phenylalanine appeared In the medium only
after growth of types A or 0, and hydroxyproline appeared only after growth of type
E. OrIg. art. has: 2 tables and 3 figures.
ASSOCIATION: Institut epidemlologii I mikroblologii im. Gamalel AMN SSSR, Moskva
(institute of E.-pidemlology and Microbiology, AMN SSSR, Moscow)
SUBMITTED: 12Dec62 DATE ACQ: 03Feb64 ENCL: DO
SUB CODE: AM, BC NO REF SOV: 002 OTHER: 009
Card 2/2

-VANOV.A. SLR,~!-.YEVA. T'
Cn-ange~- In tne n~---.ogen content of bouillcn from dried KPD
pre- k,
, pa*-!; --or, in -,.he prr,,-,ess of growth of types A, B, C and E
,:~f -u-I -1.9,r, paLholgeris .Zhur. mikrobiol., epid. i immun. 41
n o 1 8 (MIRA 18:2)
'olk--i mikrobiolog-*i imeni Gamalei AMN SSSR,
Me k-za.

J)JIWAJ~) 2 RO
A C CAN I 1'600643 .1"OURGE COM", U11/0016/65/(OU/001/0112/01.16
AUTHOR: Sergeyeva, T. I..o Orzuyev, M. 1.
_777 _777.
ORG: Institute of Epidemiology and MicrobiOlOF-V IM& N. F. Gamaleya. ANN SSSR
(Institut epidemiologii I m1krobiologil AMN 3.53M)
TITIE: Toxigenic properties of Clo tetan-listrains Isolated from soil
SOURCE: Zhurnal mikrobiologlij epidemiologii I irmmmobiologii, no. 1, 19650 132-116,
TOPIC TAGS: toxicology, bacteria, bacteriolopy, soil bacteriol
ABSTRACT: The authors compared growth dnnanClcs and t-)xitk
i production in
strains ot the C1. tetani isolated from Tadzhikintan and Uzbekistan soils
and in laboratory strains. They found that the growth or the soil strains
began sooner and was four-five times more r%pid Win that of the labora-
tory strains In a variety or liquid media (Gluzman's broth, Marten's
broth, canein-yegetable medium, broth rron dry whale liver-yeast medium).
The soil strains produced the most potent to-xins in G.-luzmans broth,
whereas the laboratory strains Droduced -Loxins of almost the -same
titer in all the media. The peak of toxin production by the soil strains
occurred during the first 24-48 hours of cultivatioa, but on the 6tb day
.the titer of the toxin decreased 2-10-foldl dependiag an the strain. The
maximum toxin titer of the laboratory strain occurred on the 3d-4th days
and remained unchanged to the 6th day, after which it grodually decreased.
Card 1/2 UDG:__ 5_7L454w!55l-W7.t_29_

ACC NR: AP6006(Y+3
Growth and spore formation of both soil and laboratory strains began sooner and
was more rapid in the broth made of dry whale liver-ytiast medium than in all the
other media. The activity of the toxin in this mediini reached a peak during the
first 3 days but decreased sharply by the 6th day of cultivation. The whale
liver-yeast medium is recommended as a means of detecting Cl. tetani In the
environment, with only 3 days of cultivation required,. Orig. art. has: 2 tables
and 1 figure. [JPRS)
SUB CODE: 06 / SUBM DATE: OlFeb64 / ORIG REF: 005 / OTH FEN 002

fkl~, Ell K.
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i. TnsrJtut, ep-,Jemij'cgi- cF) mc, n
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AYN'

ACC NRt AP601637,4
JK
SOURCE COM
loon/00161
AUTHOR: Serp-eveya, T. I.--Sergeeva T. I.; Matveyev, K. I.-44atveev., K!. I.;
Vasilevskiv, V. L.-Willevsky, V.
ORG: Institute of Evidemioloy-y and Yde robioloxy im. N. G=alpya. AMN SSSR_ Instit ut,
epidemiologii i mikrobiolog'ii AMN SSSR)
TITLE: Current tetanus prevention in the USSR and it:3'effectiveness

SOURCE., Zhurnal mikrobiologii, epidemiologiii i immumbiologii, no. 6, 19650.11-14"-
TOPIC TAGS: immunization, human ailment, bacterial dLsease
ABSTRACT: The basic measures planned for the 1961-1565 -period to reduce and:
'
'
:the zonal pAtterns'of
;eradicate tetanus In the USSR were 1) study O
f
'
l
f the entire r6r6l 'population Iti zones,
.tetanus Infection'; 2) Ammunizatio
lof high Infection, ioe.9 w4th an I-n'aex of 3 pet-100tC00-or higher; 3) (;0m-.'
i
duction.
L.pulsory active immunization'of all chlldren;'a~d 4) widespread Intro
of active-passive tetanus~Oreventl one Analyses of the "results of m6asurea.'
Itaken in the 1959-1963 period show that the Incidence of-'the disease I
,declining after only 3 years-of the 5-year'pl'a'n 4o*r tetanus control., Buf
~in spite of the higher incidence of the dIsqase lh'tte r6ral populationt

,in only a.few republics I qiacclnatlod moreintense In r al areas than In"
tur*
towns@ Another. reason why, -the results are,n6t--be
one-half or one-third of-vacolt*A a to-ovaeoinated.:
ipublics only
.1p _ppVond ar
.
Cnrd 1/2 UDC.6 616.981-551-~084 (47)

ACC NRI AP6016374
l
so, new active-passive methods of tetanus treatment. are.not being applied;
A
'in most republics. 2he authorB.recomend t4at compulsory vactination be.
icarried out in all rural areas where there Is an Inelde"'ce of 2 cases of
R~tetanus per 100000o 7hey'l ;Ialso suggest further aWdy ol'the zonal pattern A
;of tetanus In'ordek to pr6W& bet ter. Oirl entadon~"for ddbsequent. 'anti
tetanus measures. Orik-. art. has: 4 tables*' [JPRS,
SUB CODE: 06 SUBM DATE: 22SeP64 ~ORIG W-A 005

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