SCIENTIFIC ABSTRACT HADARAG, EL. - HADLIK, J.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R000617810013-4
• Release Decision: RIFPUB
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: January 4, 2017
• Sequence Number: 13
• Publication Date: December 31, 1967
• Content Type: SCIENCEAB

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RUMANIA/Pharmacology. Toxico16~y. Antibiotics.

Abs Jour: Ref. Zhur. ,-Biol.~ No. 22~ 19~8s 1029~3

V

Author

Inst :

Title :

Oeriu, S.; Balaneseu, I.V.; Burulana, L.;
Hadarag~ El.; Niculescu, P.

The Effect cf Some Antibiotics and Synthetic
Chemical Substances on Hyaluronldase and
Hyaluronic Acid.

Ori~ Pub:
Abstract:

Probl. terap., 1956, 3, 159-172

The influence of streptomycin~ preparation Io
(sulfosalicylate-allylthiocyanate-streptomyc~n),
pencillin as well as PAS, sulfosalicylic and
salicylic acids on the system of hialuronidase
(I) - hyaluronic acid (II) was studied. Ail
these substances activate the I-II system.
Pencillin stimulates it in small concentrations

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� ~FBURI3IANA, L.M.; }L~DARAG, ~

Adaptive modifications of the erythrocyttc phosphomonoesterase in the
course of t,he phylogenetio evolution. Stu~ii cero biocb{mte 5 no.3~
3?7-382 '62.

1o Catedra de chimie biologica, FacultateA,~'.,d~(,medicinn veterinara,
Bucuresti.

V

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HA?JtAN, C-h.~ CIULEI~ i.; ~it]~I, ~.%; .DO-TAT-LOi~ ~b~DARAG~..ETLena;
Db$~IT~U-C~L, ~ia~ B~CI~ f.

Buo~ost, Fa~aci% No 5, ~ay 1963, pp 271-283

"Cont~bu~ons ~ the ~tu~ of Gek~o Gecko L. ~ract."

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BURUIANA, L.M.; HADARAG, El.; PAVLU, V.

Research concerning proteins in seminal plasma. Studii cerc
biochimie 5 no.4:507-516 '62.

1. Catedra de chimie biologlca, Facultatoa do modicina
veterinara, Bucua'esti.

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1. Chair o� Bio~o,,]cr~], Chemisbry~ Tnstitute of Veterinary Medt-
cine~ Blmtlareato Submitted December 31, 11963.

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.... ' ~ ! ~ ' ~'. I!' q!~: -~'~l~l!~:;~ ~ '![JP '.'

Particular sensitivity to heat of some cereus-enthracis-mycoides.
phage strains. Arch. roumo path. expo microbiol. 23
S'63

1. Travail de la Fac~CLte de .~e~icine Veterinaire et ~u Centre
National de Pha~e~Re�ere~oes B~cares~.

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CZ/ouS;~/[;~J/0 x5/oo510,~0~1o,~o'2, ~

OS,S: Chair of Pharmacology,. Faculty of Medicinc, Brno (Farmakologicka katedra
lck. fak. )

the l~th Pharmacological Meeting in Smolenice l0 Feb. 1966]_

SOURCE: Ccskoslovenska fysiologie, v. 15, no. 5, 1�66,'402

TOPIC TAGS: toxicology, pharmacology, physiology, biochemistry,
s;api~ylococcus toxin

ABSTRACT: Previous investigations have confirmed the ability of certain com-
pounds to counteract the spasmodic effect of staphylococcus toxin. The anti-
spasmodic and relaxant properties of such compounds may be inhibited by calcium.
, Recently~ these antisl.)asmodic pro. perties and the effect of talc', xum upon them were
* studied in chlorpromazine, LSD}~gsynthetic phylline, magnesium, nitrogen, NaCN,
and DNP. The inhibiting and relaxant effects of chlorpromazine and LSD were
suppressed by an increase of calcium in the nutrient solution. The inhibiting effect
of synthetic phylline could be controlled both with calcium and with washing; how-
~_~C~rd 1/_2 ~

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"ACC

eve:k', c~,icium did not change its relaxant cfi'cot. In these tests calcium could be
replaced wi~h barium and st~'on~ium, bu~ not with magnesium. Spastic reaction
the staphylococcus toxin was observed in isolated smooth uterine muscle under
conditions of anoxia and metabolic i~ibition. It was shown that NaCN and DNP
suppressed the onsel of spasms; after flushing ou~ NaCN, the spasms developed,
whiTLe spasms did nol develop after flushing out DNP. [WA-50]

SUB CODE: 06/ SUBMDATE: none/ ORIGREF: 001/ OTHREF: 002/

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~-1"I'I$2.,.b7 ~- ~ "� '"-"" ' d

AP6032378 SOURCE CODE: CZ/0053/66/0).5/005/0403/0't03

AUTHOR." Hadasova, E.; Gulda, O.

ORG: Chair of Pharmacology, Faculty of Medicinet Brno ('Farmak�logiclca ,
katedra lek. fak.) '

TITLE: Pharmacological dynamics of staph,Ylococcus toxin,l~ Part' II [Presented.
the 1.~t_h_~ha_~?_a_c__o.!c.~i..c__al___N[' eeti_n.g, i_n_~S..m..o!..enl..e e.. !..8 .Feb:. 1. .9_~'] . . ..: ..

~OURCE: Ceskoslovenska fysiologie, v. 15, no. 5, lg~B, 403

TOPIC TAGS: toxicology, pharmacology, physiology, bio6hemistry

ABSTRACT: Dolsin, synthetic phylline, and hydrocortisone, administered before
staphylococcus toxin, suppressed typical toxin spasms in tests with a rabbitts
aorta. However, magnesium, heparine, phlegomasin, aad LSD had no effect on the
onset of spasms. The histamine-liberating effect of staphylotoxin was tested as
well. In a test tissue where calcium had been removed with EDTA0 the toxia
released statistically significant, lower amounts of histamine when tested in '
calcium-free solution. When a calcium solution was used, markedly higher

Card

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amounts of histamine were noticed. The histamine-liberating capacity of
staphylotoxin was decreased with heparine, and was completely suppressed with
hydrocortisone. [WA-50]

SUB CODE: 06/ SUBM DATE: .none/ ORIG REF: 001/' OTH REF: 003/

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CZECHOSLLVf~I~'JCheuical Technology. Chenical
Products and Their Applications.
Water Treatnent. Sewage.

Abs Jour : Ref Zhur-Khiniya~ No 7, 1959~ 23804

Author : Berka~ J., ~ Hlavikova~ Ye. ~
Jelinek, V., oN-oVak, Z.
Inst : - �

Title ~ Investigation of Operation of the Quick
Acting Sand Filters.

Orig Pub : Voda~ 1956, 35, No 12~ 382-387

Abstract : The investigation was conducted on a seni-
connercial scale. Filters (F) had areas of
1 x 1 n and O.1 x 0.1 n -and were equipped
with devices for the re~oval of water sm~p-
les. and for tho pressure noasureuents at

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CZECHOSLOVJ~KIA/Chonic ~l Technolog�. Cho~.~ic,~ H-~
Products and Their Applications.
Water Treatment. Sewage.
Abs Jour : Ref Zhur-Khi~iya, No 7~ 19%9~ 23802

Author : Had~k~
Inst : - -
Title : Effect of Reclrculation of Coagulate on tho
Purification of Water.
0rig Pub : Voda~ 1956~ 35~ No 12~ 392-394

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Abstract ~ It has been established that coagulate (O)
forned in the coagulation of surface ~/aters
with FeCI~ and A12(SO~)3 (I)~ loses rapidly
its adsorption capacity. The effect on the
purification of water is negligible because
of absence of tho perik~etic coagulation.

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F, xh[bl'ts on water' s~pply and waste water puri~taation at the
[.~rno I~ternat�onat Fair. Vodni hosp lA no.ll~A]A-A35 '6A.

,. . :~! ~ ~'!~'~-' ;!~.'~i!:'i :!: i i
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" : ' I ! ! i !'ii ~ dl~':.

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H~[DEK, .liris inz.; SMC~';i.i~'~i ~ .~os{~,.!',

A neu water treal,[~,nt ?D~nl, for the
hosp 12~ no.8:289-291 '64.

1. Water Resources :,',~nailement Agency of the city of Brno (for Hadek).
2. Hydroprojekt, Ostrava (for ~�molka).

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; .... ~t ~ i ~ ' ~ ' ',i'~:' ~IH!:I

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AUTiIOR:

H~dek, V&clav

2 22:
Z/O28/60~J~O/O03/O01/O0�
D253/D302

TITLE:

PERIODICAL:

Variations in the intensity of cosmic radiation

Pokroky matematiky, fysiky a astronomic, no. 3~ 1960,
249-2?5

TEXT: The article is concerned with research and results in the field
of the periodic variation of cosmic radiation. During the IG� the number
of stations was increased to 126, distributed all over the Earth's sur~
fa~e. In Czechoslovakia there were two statisna: Lomnick~ ~tit lat. N
48 , altitude 2634 m, and Praha - Karlov N 48 , at sea level - ~11
equipped for recording ~ - mesons~ and neutrons. The values are shown
for the average daily vhriation obtained at l) Nuaacayo 2) Cheltenham
3) Christchurch and 4) Godhavn obtained for an 8 year period (since
1936) ~ - particles were measured and the 'daily variation - amplitude
was ~round 0.15 - 0.20~. From these curves it is clear that' the geo-
magnetic latitude has a great influence on the amplitude and on the

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Variations in the intensity,.,

26322
z/o28/6o/ooo/oo~/oo~/oo5
D253/D302

position (time) of the daily maxima and the question arises to what
extent temperature influences these variationse The work of Z.�o
Dorman (Ref. 6: DAN SSSR 95, 49, 1954) shows the opposite to be the
case~ as the tempera2ure has a compensating effect. Observation values
for the amplitudes at the Czechoslovak stations are given by J.
sad~ P. Chaloupka, V. Kade~ka, T. Kowalski and P. Mokr~ (Ref. 7:
� gas Fys.gs 150~ 1959)o Apart from these 24 hour variations there
are 12 hour variations and the results are given of the Fourier
analysis for the same stations mentioned earlier. Other influences
have been observed: One of the more important is the direction from
which the particles arrive; further there are seasonal variations
as given in Fig. 4e observed at ~oscow during 1951-52.-A further in-
fluencing factor is a magnetic storm. The increase is shown of the
amplitude of variation during the magnetic storm at Tokio, June
1948. Magnetic storms also have some influence on the time of the
daily maxima and this is also shown in tabulated for~. Variations for
the following periods are shown in Fig. 10: 1) 1937-42~ diminishing

Card

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Variations in the intensity,..

26322
z/o28/6o/ooo/oo3/oo1/oo5
B253/D302

sun activity; '2) & 3) 1942-44 minimum sun activity; 4) 19,14-47 growing
sun activity; 5) 1947-52 maximum activity and diminishing. �) & 7)
1953-55; 8) 1956. The drop of intensity of radiation has been observed
over thirty years (for ~ particles, at sea level) during magnetic
storms: the pattern is typical, a sudden drop at tile beginning of tile
storm, followed by a slow growth. The results show a similarity of
observations at widely spaced observing stations. On the increase of
cosmic radiation during eruptions in the ciwomosphere, iL is noted that
these have been observed during the last 20 ye~mse these eraptions are
of much greater intensity than any of the previously mentioned varia-
tions, and observations are shown at Godhavn~ Cheltenham~ lluancayo,
Christchurch, and Climax Colorado (5500 m alt.) on November 19, 1949.
Observations of the neutrons at blanchester on the s~e date are also
given. Against this increase of about 600~,the ionization increased
only by 11%o The latest observed ~ncrease~ took place on February 13~
1956 (Ref.46fLGold, Ii. Elliot, The solar cosmic ray outburst, 1956~
February 23, (collection of cosmic ray, solar, ionospheric and magnetic
data relating to the event, Royal Greenwich, 0bservatory~ 1956).

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26 22
z/o2e/eo~ooo/oo3/oo~/oo5
Variations in the intensity~.o D253/D30,2

There are 20 figures, 5 tables and 47 references: 7 $oviet.-bloct and
40 non-Soviet-bloc. The 4 most recent references to the English-

-language publications read.as follows: R.P. I[anes Phys. l~ev., 98',
130, 195~; P. blorrisont. Physo Rev., ~01~ 1397~ 1956; To Gold~ ti.
Elliott~ "The solar cosmic ray outburst~ 1956~ FebruiuV
(Collection of cosmic ray, solar, ionospheric and magnetic dat~
re~ating to. the eventot Roya! Greenwich Observatory~ 1956);
Parkert Physo Rev�~ llO~ 1445, 1958.

Fig. 4

(For Fig. 10 see next card)

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HAIIKK, V.{ KULKA, M.

Contribution of beta and gamma radiation activity to total
dose intensity of fission products. Chekimsl �iz zhurnal lA
no. 61~11-&16 '~.
� Institute of~cromolecular Chemistry, Czechoslovak
Academy of Scie~es, ~'ague 6, Na Petrinach (for Hadek).
2. Tesla Pardubice Nati%nal Enterprise, Research Institute
Premysleni (for Kulka).

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HAD~I, HUlO

D~v~lopm~nt of ph~m~�~uti�~l industry in th~ ?~opl~'~ R~publi�
of Ch~n~. Sh~n~t. pop. 1~6-50 ~6~.

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}LqDERf4A, J., Dr. of Law

Kraj Comrt (Krajsky soud), Ostrava

Prague, Praktick~r lekar, No 13-14, 196~, tEF' 5]O-532
"Tacituzn~ity in Interz~lpted Ages."

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I[ADEIUf, A~ j,

Home ,~-isits of 'toddlers from childr~n*s homes 'from the
legal standooint.. Cesk. pediat~.

1. Krajsky soud ':.,' Ct~traTe.

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mciats. 1~ comL,,t/uf un RC oscilht~t ~f b~idicd-T
typu, a IOkc/s ~ry~t3t ~tatot %'~ ~C f~quclt~
~ividc~ ~nd � c.r.t. ~c

c~st~l oscitla~or and thc fou~-s~don RC
divider ar~ c,.~lo~d rot o~ural~ f~u~ncy
mont. t{~ lin~: b~s~ of thc c.r,t.
sub]nullipfc u~ I~,C c~tal ~rcq~Y. ~he fO~ctkln{a~
ur thc RC d{vld=r N {llustra~l ~ ii liuHl~r of

'' i

i i'{ '/'.!-:

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V. S. PoDov's ElectrlC ~easurements and ~;~as~zrinz kppar.~tus; a book review.
m. 556. (SLABOPROUDY OBZOR, Vol. 17, No. 6, June 195~, Praha, Czechoslovakia)

SO: Monthly List of East European Accessions (E~L) LC, Vo!. 6, No. 12, Dec 1957. Uncl.

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HADER/4A, S.
HADERKA, S.

Instruments for electronic measurements in high voltage electric engineering,
p. 542

Vol. 45, No- 11, Nov. 1956
ELEKTROTECHNICKY O~_ZOR-
TEC~OLCGY
Praha, Czechoslovakia

So: East muropeanAccessions, Vol. 6, No. 3, M~rch 1957

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I.,~-~1~'~'' ,~'l~'~ ! ~ ', J' ~ ~;: ~?. ~;,-'] ) 'i ' ~ ' ': ~PI~I ~1~!~

HADE[~5:A~ S.

A precise measurement of time and frequency, p.13~.
(Sdelovaci Techinika~ Vol. % No. ~ May 19~?~ Praha~ Czechoslovmkia)

SO: MonthlyList of East European Accessions (EEAL) LC. Vol. 6, No. 9, Sept. 1957. Uncl.

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H.iDERK:I, Stanislav

Vysokofrekvencni mereni. 2/dtl/. (High-Frequency Measurements. Vol. 2; a
university textbook. 1st ed. illus., bibl.) For the students of the Faculty of
Radio Engineering in Podebrady.

Bibliogra�icRy katalogs CSR, Ceske knihys No. 33. 24 Sept 57. p. 722.

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Ltthlum.bile luhri(atmf l~e~el. I~n,lrc �1mm nmi

e.irlh. ~ I~l~l,el h~.l ~n ~chl ,n. ~t(I.I), ~fl. nfl.

llllili~ i,il. (]lr:l~ lilllillq, lliilill' ~[ Iht llilillll dj lJlh
I. ~ l.I ~%:1: writ exaiml. TJI'~ with mine than

I~..~lifl~ry h~.l::~q. Thc AS~M ~cttat~
d~lnI ~la, ~'h~ ~millr ~ ~ll. rith~ N.

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Hr! ? f"�' Iq'. 7.

ri[~l~:u~n~/Chumzc,.1 Tochnolo/;yo

Gh,~'mic'~l Products r~nd
Thc ir Appiic~qticn--Tro:-:tmunt of natur?.l

Abs Jour: Rof" , '
z, hm-kh:lmiya, i,~o 3~ 9320

Author : ~yul, G., Vnmos, E , and !.a~ Io
Inst. : Not given
Title : Tho production of Colorless Oils by Chromatogra-
phic No thods

0rig Pub: i.[agyar Komikusok Lapja, 1953, Vol 8, No 9,
249-255 (in Hungarian)

Abstract: No abstract

Cared 1/].

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HUNGARy / Chemical Technology. Chemical Products and Their J-9
A~plication - Treatnent of natural gases and petroleum.
Motor and rocket fuels. Lubricants

Abs Jour
Author : Uadfy Kovacs Ivan
Inet : Not given

: Referat Zhur - Khimiya, No 2, 1958, 5953

Title

: Control of Spent Oils by Chemical and Physico-Chemicsl
Methods

Orig Pub : Kozlekedestud. szemle, 1956, 6, No 5, 174-177

Abstract

: On chromatography of spent oil on paper (a drop of oil is
placed on filter paper) there is formed a core of more
polar compounds formed in the course of the operation
process. The absorption of light by this core is measured

Card 1/2

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HADHAZY, CS.

"Investigations .of chondrogenesis. I. Definition of problem and general
histological investigations of neoplasta." In aerman, p. 139.

ACTA BIOLOGICA. (Magyar Tudomnyos Akademia) Budapest, Hungary, Vol. 9,
No. 2, 1958.

Monthly List of East European Accessions (EEAI) LC, Vol. 8, No. 6, June 1959.
Uncl.

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Resorption o:E insulin anc~ ast~molysin by the nasal mucous membrane.
Acta med. hung. 12 no.1-�:107-114 1958,
1. I. Medizinische [linik und Anatomisch. Histologisch-embryologiaches-
Institut der medizinischern Universitat Debrecen, Ungarn.
( I~ISULIN, admi~.
nasal tampon, absorp, in diabetics & exper, animals
(ASTHMA, ther.
epinephrine - posterior pituitary extract prep. admia, by
nasal tamp. om, absorp, in man & exper, animals (Get))
(~PINEPHRIN~, ther. use
asthma, admin, of epiuephrine - posterior pituitary ex-
tract prep. by nasal tampon, absorp, in man & exper, an-
imals (~er))
(PITUITARY GL&~D, POST~RXOR, e~tracts
posterior pituitary extract - epinephrine prep. in ~her.
of asthma, admin, by ~asal tampon, absorp. An man & exper.
animals (Ger))
(NOS~. phye lol.
abeorn, o� epinenbrine - pos~erior pituitary extract prep.
& insulin through n~sal mucou~ membrane in cllm. s~udiea
& exper. (Ger))

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~; ~ i: ;'.~:~'-~ :~fi~'~[:-I:,:l~~ :~ I ~ l~'llL*~

HADP4~ZY, Cs.; KOSTEN�Z~�~, K.; 0I~.H, E.

Investigation of chondrogemesis. Ii. Conditions of vascularization in the
formation o� Joints. In German. p. 271

ACTA BIOIDGICA. (~eEyar Tudo~anyos Akademia) Budapest, Hungary. rot 9,
No. 3, 1959

Month~r List of East European Accessions, (EEAI) LO, Vol. 9, No. 1, Jan. 1960
Uncl

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 "APPROVED FOR RELEASE: 09/17/2001 CTA-RDP86-00513R000617810013-4
I1!: ~1::' ~ I'!, ,~x'.'J,~|'', ':,-::! i': !t - u~..~,: ~Hi--,~!l~.l:~:,l.,i:- t .! ~ ii: .-:1 hHl;~i~l ~.~H~c~'l~'""l.I

HADHAZY Csaba (Debrecen 12, Anatomia, Ungarn.)10LAH, Eva (Debrecen 12,,
� ; " ~- ~. ~ ^~-0 Maria (Debrecen 12, Anat~!ia, Ung,rn.); KQS'II~2tSZKY,
Katalin ~Ueorecen ~ -
investigations of chondrogenesis. V. Data concerning the mechanism of
reduced respiration in the course of neodifferential chondrogenesls.

1. Institut fur Anatcmte, Histologle und ~mbryologie (Vorstendi: St.
Krompecher) der Mediztnischen Universitat, Debrecen.

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HADI{AZY, Cs.; OIJ~H, Eva }{.~ LASZLO, Ma~ia Bo) KOST~:!,~SZKY, Kat'~lin So

Studios on tho fox~ation of c~t~ago. VI, ~aorobic and aerobic
glycolysis ~ the regenerat~g jolt s~face. Acta biol. acad.
Sci.

1. ~stitut ~ ~ato~dc~ ~stologie ~nd ~b~yologie, Me~zinische
Universi~t ~cen (Vors~nd: I. K~'~pechex')~

T OLZS )

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~ ~ I (; '~:~c~-~'-'~!J~:L!Ji~;, ~:J ':i~-~. { J :~' : ~l II;lt~.~:~l ~fli~:~:~'l--:"l~l'~lTM ! ~ ' :'"~:' ''~

OLAH, ~.va; HADRAZY, Cs.
Studies on chondrogenesis. VII. The content of tissue hexosamine
in regenerating Joint surface in different stages of regeneration.
Acta biol. acad. sci. hung. 13 no,2:127-138 '62.
1. Institut ~ Anatemie~. Histologie und Embr~elogie der Medizinischen
Universitat, Debrecen .(Vorst. and: St. Kr?mpech~e~r)~.~
(MUCOPOLYSACCHARIDES)

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Studies on ohondrogenesis. VIIIo Histochomicml atudy on mucopoly-
saceharides in regenerating Joint surfaces� Ae'~ hiol, acado sci.
hung. 13 no.2~145-168 '62�

1o Institut fur Anatomies Histologie und Embryologie der Medizinischen
Universitat, Debrecen (Vorstands Sro Xrompeoher)o
(CARTZLAGE) (MUOOPOLYSACCTLU~T DES)

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HADHAZY, CSo; OLAH, Eva Ho~ KROMPECHER, Sto

Adaptattve shift of tissue metabolism in local hypoxta
resulting in higher mucopol~saccharide content. Acta biol.
acado sci. Hung� 1~ nOol167-75 '63.

1. Institute of Anatomy, Histology and Embryology, Medical
University~ Debrecen (Head: St� Krompecher).
(T~SS~ ~rA~0~.~) (~CO~)~SACC~A~S)
(ANOXIA) (CARTILAGE) (CARBOHtDRATE ME?ABOLISM)
(Ca r LAT 0 T SSUS) ( OSm S)

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OL~H, Eva, if H.; HADHAZY, Cs.~ MANDi, B.
Studies on cartilage formation. IX. ~-ta biol. acad. sci. Hung.
16 no.1:25-34 '65..

1. Institute of Ahatomy, Histology and Embryology, Medical
University, Debrecen (Headt St. Krompecher).

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HUNGARY
HADHAZy,~..:~s~_~ KOSTENSZKY. Katalin, �~NDI, ,~rnabas, OLAH. Eva: Medical
~J~�~sity of Debrecen, Institute of Anatomy, Histology and Embryology
(De~rcaeni Orvostudomanyi E~yetem. Anatomiai. Szovet- es Fejlodestani In-
tezet).

"Changes in the Serum Hexosamine Concentration of DoMs Following Thymectomy
and Arthroplasty."

Budapest, Kiserletes Orvostudomany, Vol XiX, No 1, Jan 67, pages 94-97.

Abstract: [Authors' Hungarian ~ummary] Thymectomy wa~ performed on 6-7 we~k
old puppies and was followed by arthroplasty '3 weeks later. Serum hexes-
amine determinations were made previous to the two operations as well as on
the 7th, 33rd and 7Oth day, after the second operation. It was found that a
considerable increase in hexosamine concentration develops following the
thymectomy which increases'further by the 7th day after the arthroplasty
to return to normal within a month. Animals belonging to the control group
reacted essentially in a similar manner, although to a lesser degree, follow-
lng arthroplasty . It is assumed that the changes in the hexosamine level are
of identical character in both cases: aspecific and a result of the surgical
intervention. 8 Hungarian. 14 Western references. [Manuscript received 25
Mar 66. ]

1/1

ARi~:~O~I~(~RLR[~S~. ~0. 9 / 17 / 2001 CZA-RDP86-00513R000617810013-4"
Effect of heparin on the growth of the herpes group of viruses.
Acta microbtol, acad. sci. Hung. 12 no.2:145-1~9 '65.
1. Institute of R~erobiology (Director: L. Vaczi)~ University
Medical School, Debrecen. Submitted November 28, 196&.

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institute of ;,~ic~obioiofy (director: VAGZi, L.) (~sbreceni Orvostudomanyi
y~-~e~e~ MikrobioloKiai Intezet)

"Studies of the influence of Endogenous Regulatory Factor~ on the Growth of
the Herpes Simplex Virus."

Budapest, Acia ~:%crobioloKica Academiae 5cientiarum Hun;,aricae, Vol XIII,
No 2, 1966~ ~e~ 1Lj-150.

Abstract: [English al'ticle, authors' English summary modified] The Crowth-
inhibitory ac%ion of he~rin on the Herpm simplex virus in hu~an eF~bryonic
fibroplast and HeLa cells was enhanced by certain biosenio amines and hor-
mones (his~mine, adrenalin, serotonin, cortisone, hydrocoFtisone, ACTH).
The inhibitory action of he. Fin could also be demonstrated in rabbits in-
fected with herpesvirus subcutaneously. The inhibit[on manifested itself
by a decrease in cutaneous lesions and by the local gro~h of the v~rus.
~ ~stern European, 15 Western references. [~'snuscript received 9 Dec 65.]

1/1

- 34 -

L 38603-66 T JK /20~.i~E '~l~-.-~-,,~'/,~Y~-/[,/nll/O1A9 ........................
AUTHOR: Horvath, Eva (Debrecen); }{adhazy, Gyorgy (De. brecen)
eRG: Institute of Microbiology/he~ded bY: Li va6~i/, Medical Universit[ of Debrec~
(Debrecern, i Orvostudomanyi Egyetem, Mikrobi�iogiai Int~z~'~-~---
TITLE: Effect of heparin on the growth of the Herpesugroup of viruses
SOURCE: Academia scientiarum hungaricae. Acta ~i~r0biologia, v. 12, no. 2, 1965,
l&5-149
TOPIC TAGS: virus, virology, pharmacology
ABSTRACT: The effect of heparin, on the growth of Herpesvirus varicellae. Cy~omegalo-
virus and Herpes simplex viru~in secondary human fibroblast, HeLa and secondary
human thyroid tissue cultures,~has been studied. Heparin was added to the cultures
at different times following infection. The titer (Herpes simplex virus) and focus
count reduction (Varicella and Cytomegalovirus ) was the highest in cultures to
which the virus and heparin were added simultaneously. The degree of inhibition
was dependent on the actual concentration of heparin and the type of tissue culture
used. In the presence of l0 ug/ml heparin, the infective titer of Herpes simplex
virus was reduced by 1.5 and 3.5 logs in secondary human fibroblast and in HeLa cell
cultures, respectively. Experinmnts with intracellular cytomegalovirus have
that heparin inhibits only the adsorption of free virus and has no influence on the
penetration and cell-to-cell transfer of viruses carried by infected cells. The
authors thank Mrs~ and Mrs. E. Doczy for excellent technical assistance.
Orig. art. has: 3 figures. ~JPRS: 33,5001
SUB CODE: 06 / SUBMDATE: 28Nov6~ / ORIG REF: 001 / OTH REF: 013

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Hb~OA~Y

VAGZI, Lajo$, HORVAT~. Eva~_H~DHAZY, O~orgY; M~Ical ~lversity of ~b~c~,
Institu~ of ,.icrobioloRy (d~ VAt'I, [. ~ (~b~ceni O~ostudo~l
E~cm, Mikrobtologtai In~eze%).

"S%udl,s of ~he Gondl%ion~ of In%.rfe~n ~r~uo~ion b~ Gall~ Infeo~ed WI~

Burial,t. A~ M~o~b~olo~a A~demta~ S~len~mr~ H~arl~a~. Vol X~I,

of an ~nh~b~o~ prtn~ towa~ v~ru~ g~wth ~ ~n~d

H~pe~v~r~ var~ellae and G~o~gal~v~ru~. ~ ~hr~ vtru~ w~ fo~d

~ount ~ c~tures sup~r~g the grow~ of Gyt~ugalovirus, ~d ~ even
lesser ~oun% ~ cells ~tfected wt~ 'He~s s~ viF~. The v~us
hibi~ subs~nce ~s ti~m%~ in sec~ h~n ~mb~c. fibroblast,
He~ ~ III/1 pe~nent mo~ey ki~ey cells. The highest %iter, were
&~ed ~ ~e ~tter g~up. The ~htbt~ subs~e Is et~er ~terfe~
or an ~%erforon-llke 9~ct~e. Tho rela%i~shtp ~een ~e ~ount of
~tbi~ subs~e ~r~uc~ and ~e progress of wt~ ~feotlon.
%t~sue c~l~re ts disc~s~. ~ ~ste~ g~, ZZ Welte~ ~fe~ncc~,
1/1 [~c~pt r~eived ~ Aug 65, ]

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VACZI, L.j HADP~Z~ Gy~ HORVATH~ E?a

The influence of temperatire on 'the multiplication of the
PR8 strain of influenza A virus and on the interferon pro-
duction by the vin~ infected cells. Ac~l microbiol, acad.
sci. Fzungo iO no.4:397-402 '63 - '64

1. Institute o~ Microbioio~ly (Directol'~ L.Vac~i), ~iversity
Medical School~ Debr~cen.

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K:IOLL, Jozsef, l)r of med. sci., $CHEIBER, [:szter, F~\GYAR, ..Kalman,
~FRIED~NN, T~as; Medical University of Budapest, Instltut? o~ Pha~-
cology (Budapesti O~ostudommnyi E~etem, Gyo~szertani ~tezet).

"Cellulin: A Cell Membrane Subst~ce With a Ca~diotonic Effect of a
S~cial M~e of Action III. The Pre.ration of Cellulin-Con~in~ng Substances
and Their Biological Titration in Frog and ~mmalian Hearts."

Budapest, A Mafyar Tudomanyos Akad~m~a V. Orvosi Tud~anyok Osztalyanak
Kozlemcnyci, Vol XVI, No 4, 1965, ~ges 339-349.
~Abst. ract: [Authors' Hun~ar~n s~a~ modified] It was sho~ that, after
:washing ~rious ma~lian tissues with a suitable ("sealtag") solution,
cellul~ enters the solution. ~e ~side surface of frog sk~ proved t0
'~ the most successful ~ this ~spect; for this reason, it was used for
the develo~ent of the %ta~a~ p~ration" meth~. ~ese "stan~rd pre-
~rations" are lyophilized, yellowish-bro~, completely water soluble ~w-
der,~ O.7~3 m~ of which conta~ 1 ~lt of cell~in. The biologi~l titra-
tion of cellulin ~ frog hea~s was also worked out. ~e effectiveness
measu~d ~ ~its. ~e measu~ment is ~sed On the fact t~t the hea~,
sto~ed in the diastole and in~*s seluti~n conta~ 0.2 ~r cent
KC1. can ~ ~de %~ f~ct~cn a~a~ ~ Such a K c~centratiun ,~y ~ the
.-

- 81 o

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I II~ GARY
Budapcst, i Maffyar Tudomar~os Akademia V. Orvosi Tudomar%yok Osztalyan~%
Kozlomenyoi, Vol Xg'Is No 4, 1~65, pages 339-3&9
use of cellulin. The ca~diotoni� effectiveness of our ,,standard prepara-
tion'' was also determined on the cat auricle and on a papillary muscle
preparation: similar to the observations on the frog heart, the effec~
of K on heart stoppage wa~ greatly a~t&go.-tzed ~Y cell~li~ ill these pre-
parations as well. A strong potentiating synergism was observed between
cellulin and Ca in both frog and mammalian heart preparations. Tho
,,standar~ preparations" conrail% 2.~-& per c~15 C~. F~tr.:ction of the Ca
with Na o~te er complexing agent will inhibit the specific cellulin
activi%y on the frog heart. A~ ex~rac~ion metho~ was also discovered, the
resultan% pr~pa_-ation of which has the specific effec$ characteristic of
C~_1~,,1tn on tho �~g hea~ but has no effe~ c~ the "lna~an
2 Hun~&~, 1 W,.t~n re~er~coo. ~muocr~pt ~ec~L,~ 10

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~AI~A~Y~ S.~ LELEES, Oo~ KA]tMAZSIN~ L,
Poltnat&l development of the ~e~l cortex. Acta ~r~. h~. ~
no.2:2~-215 195".
1. Institut ~ A~to~e, Histol~is ~t ~ryol~ie 6er
schen ~lversit~t, ~brecen (Vorst~d= ~of.
~st~tal ~elop. )

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HUNGARY / Soil Science. Soil Genesis and Geography.
Abs ~our: Ref Zhur-Biol., No g, 1959, 6044.

Author : Pausz, Laszlo.; Hadi, Jozsef.
Inst : Sarvar Sugar Plant Laboratory,'
Title : Soil Studies and Surveys in tho Region of thc
Sarvar Sugar Plant.
0rig Pub: Cukoripar, 1957, 10, No ll-lE, 191-194.

Abstract: No abstract.

Card 1/1

15

AF

Countrv : t{UNGA~.Y
~.921~mical Tec!molofry. Carbohydrates ar:d Their
P~~FO~ ~~~9/17/2001 ~IA-RDP86-00513R0006
Abs. Jour : ~f Zhur-~miy~ ~ 14, 1959~No 51317

Author
Institute
Title

Orig Pub.
Abstract

Sucrose
: New lleaEen~ for

~ukoripar, 1958, 11, Xo 9, 225-226
For the de%�rminati�n of sucrose in ~%er ~
new reagent is proposed: i~ solution of cam-
phor in concentrated sulfuric acia. T~. ml
cooled s~m~le, 1-1.5 ml of the re,gent~Kdded

followe~ bY a gentle shaking of the mixture.
in the Presence of sucrose the solution aequi-[
res red coloring. Five minutes later the sam-
~le is s~bjected %0 ohotometric testing.
Presented is the relation3hip between the

iCard:

L7810013-4'

H-26

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H~DI, Jozsef, vegyeszmernok.
A new reagent for dotectlng saccharose. Cukor 11 no.9~225-226
S' 58

1.5arvari Oukorgyar.

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ABS. JOUR,

A'~,~.lic~-tion~, Carbohydrates and Thnir Processing.,
: RZhY~m.~ .No l?~ 1959, No. 62435

AUTROR
INSTI~J~J
T/TLE

: P~usz, L,;~Hadi~],
: -

: De~ermi~mLion o� Small f~uan~it.ies of Sucrose
with Anthrone
: Cukorin~r~ 1058,

ABSTRACT

: To 2 ml o:f' cooled sa.n,-~]o ~re added ,~ ml of O. 5%
of an%hrone sw]fate '~:~lut, ion, f~l]owod by sha-
kin~ and after a~�~rox. 15 mJuutes by photomet-
rieal de'terminaiions with yellow light filter.
Only %he freshly DreD~tred reagent is beinK use,~
in these determlna%ions, An~,hroDe is Drenared by
the reduction of antraquinone w~.-th tin ~n ~.he
nresenco of glacial CIIsC00H with the subsequen'b
recrys%mlliza~ion from henzene-~e%ro]eum ~Lher
(8 : 1). Presented i8 ~he denendency of li~h%
~bsorn%ion on %he sucrose eoncen~r,.~on.
-- G. Yudkovich.

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H - 102

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YUGOSLAVIA

ISVANCESKI, Milorad; HA~J.!_n!id~TONO�IC.,.~Q.i_g~.; and MATIC-TODOROV, Radmila;
Department of Pathology (Patoloski institut) Head (Upravnik) Prof Dr
ZivoJin IGNJACEV,) and Neuropsychiatric Clinic (NeuropsihiJatriJska klinika)
Head Prof Dr Ufos JEKIC, of Medical College of University (Medicinski
fakultet Univerziceta,) Belgrade.

"Infantile Familial Amaurotic idiocy (Tay Sachs Disease.)"

Belgrade, Srpski Arkhiv za Tselokupno Lekarstvo, Vol 93, No 3, Mar 65; pp
283-291.

Abstract [English summary modified]: Detailed case history of a girl who
developed quite normally until the age of 10 months, then gradually
deteriorated with typical diagnostic picture, until succumbing to
bronchopneumonia at age 30 months; clinical and histopathologic data are
discussed; there were no known Jewish ancestors in the family. Two
photomicrographs; 2 Yugoslav and 22 Western references; ms rec 29 Nov 63.
~/~

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HADiNEC ~ A.

"~lblishing Results of Research Work." p. 529 (Za Socialistickou Vedu A Techniku,
Vol. 3, no. 12, Dec. 1953, Praha)

East European __Vol. 3, No. 3
SOt Monthly Lf~t of~Accessions,/Library of Congress,

1954
~rch tm~, Uncl.

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~xl, t{, with ~ttou
~oO~ ~e mmt~h~
ditions i~ au eq~l{y
sue,~h of Um si!on f~bn~ aft~ the ~pt. is grater and ~,~ ~ '

L :..,;.:: .....

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P,~UNE$CU, Aug.; HAD[RC~,, �cate~'ina

Immunological .and btoche~Ics. 1 reactivity of the histoid macro~hage
in tuberculosis, Ft. 1o S~adii cerc biochimie ? no.2:2~9-236 t6A,
1o ~.~borato~y of Biochemistry and Bacterial Physiology~ Clin{c
Institute of Phthisiolcgy~ Bucharest, Su~nitted January 30, 196Ao

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BULI~, Al,; PAU~ESCU, Eug.; HADI!{CA, Ecaterina

Dynamics of modofications of culture medium composition
during the development of Mycobacterium tuberculosis, Pt.1.
Studii cerc biochimie 6 no.4:501-510 I g3.

1. Laboratorul de biochimie si fiziologie bacteriana al
Institutului clinic de fiziologie, Bucuresti.

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BI~RZAN., Ro,~nel, lng. (Cluj); DUI.IiTRU, Acu (~;asaud); SAi;DULAC?~, O., prof.
(~b~gresti Ias[); SAVUL!'Y~CU, Benone (Buzau); IO}~ESCU-TIU, C.;
Liviu; PRAVAT, V.V. (iasi); SACTER; 0.; POPA, Eugen (Iasi);
Tudor; VOICULESCU', D~, (Bucuresti); 'BEJA/qCU, Aurel; JlA}LAS, Hobert
(Botosani); IARGHY, Tatiana~' pro�esoara (Buc,u,r,.:sti); ~.~DIRCA, I. (Sreaza)
JORA, S. Boris (Babadag)~ ROI-~;, T.) COSTACHESCU, C,V. (Constanta)

Proposed probl~::m. Gaz :~t B 15 no.2:~C~-8'J F ~,.

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POPA~ E-~-.:[ ~Iasi); FLONDOR, Paul
TO~U, Ion (Bucuresti); PiRS2;,
Victor (Rimnicu V~lcoa); BOGATU,

Solved problems. Gaz mat B 16

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MIR~N, Radu, conf. univ.; EEGREI, Veronica; MANOLIU, Lucia; POLIZU, Lucia;
VISA, Kugen; ~A~VAS, M.; GLIG~, I.; FUCHS, I.; ZOICAN, Voicu;
BAGHINA, V., prof,; _~/~,,~.CA.~, I.;IVANESCU-TIRGOVISTE, C.;
NEC, REA, M.; SPIRID01~.;--~'A~8-PLOIESTI, T.; GRIGfkRE-PLOIESTI, I-.,
prof;:BAZACOV, Gh., prof.! PAUNESCU~ Al.; MfRARU, I.; SAHAGIA,
-UD~EA, V., prof. (~alati), NIMITAN, I. (Suceava)

Observations on the Ar~]ytic Geometry Manual for the llth grade.
~az mat �iz 15 no.6:298--32t Je '63.

1. Societatea--de S%iimte~a%~m~tie~-si FiJ~LOe-~, Fit-iata Iasi (for
M{ron).. 2. Societatea de Stiinte Matematice si Fimice; Filiata
Craiova ~for Negrei~ Mamoliu, Polizu). 3. Societatea de Stiinte
~atematice si Fizice, Filiala Timisoara ('for Visa, Batvas, 61igor,
Fachm). 4. Societatea--de Stiinte Matematice-si Fizice, Subfiliala
'Petroseni (for Zoican). 5. Societa%ea de Stiinte Matematic� si
Fizice, Filiala Ploiesti (for Baghlna, Hadirca-~eeaza, tvanescu-
Tirgoviste, Negrea, Spiridon, Azabo-Ploiesti, 6rigore-Ploiesti).
6. Societatea de Stiinte Matematice si Fizice, Subfiliala Tg.
Severin (for Bazacov, Paunescu, Moraru~ Sahagia).

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"APPROVED FOR RELEASE: 09/17/2001
~. : ! si~ ~'-~ ~:'-!!,~:~'!U~l"~'l ~ '" I ~ -:. ?! t~:li~:~IIl~'j 'lIly, ill

CTA-RDP86-00513R000617810013-4

L 00159-66 N.4P(j)
ACC .SSZO A .0 555 /oon/6 /o .eloo2/oz /oz
AUTHORs H~Jieva~ P.~ Stolanova-Iv~ova,

TIT~: Co~sition of ~c~ols fou~ in w~ from concen~ra~e~ attar of Bulgari~
rose ~tals ~,~
S0~CE: Bulg~ska akade~a na haunts. Do~a~, v. 18. no, 2, 1~65. 145-1~

TOPIC TAGS: alcohol, wax. botan~

ABSTRACT.. -. This is e continuation of earlier studies oi'
.F~~� ~t'cl'. (C�~n.~.._~rend..Ac~d~ bul~., 8c~., �, 1.C5~, No 2.~ 3~) conceYnl~gi
; the chemical composi(i~n ~f ~o~oe~tr~ted a~t~r/o~ Bul~ri,n rose ~s.
This time the authors concentrated on the co~osition o~ the alcohol fraction. ,"
of the same .~x used dc?lng the earlier phases of the research. Tests ~ '
uncovered the following no~,l s~turated alcoholsl (02~OH),: ~m~ol-'

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L 00159-66
ACC~SsZO~ m, A~O2~

ASSOCIATION: Chaire de ehimie organique de l'~niwrsite de Sofia .(Department ~f

stm~mi~m, oo ~CL~ O0 ~B00~i oc, ~
{iR BBF SOY: 001 Ol'l{~ 005 JPRS �

Ctrd.. 2/2 ' ' :
.~ ................................. ,_~_.{

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. : ; ; :~ ': ' ' ~ :! ! I ' ' ' "I; Ii '""IF~~: ~iitq!J{,!~:!t~i :~]i~c11~.~ ~! IIt~

VULGHANOVo V.H.~

~ possibilities of auto-lm~izatlon in m~ntal patients,
Dokl. Bolg. akad. nauk 17 nOo1~311-31~ ~64

1o Submitted by ~ademician Io Emanuilov.

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HADJIOLOV, A.A. [Khadzhiolov, A.A.]

On the substrate specificity of potato ATP-diphosphohydrolase.
Doklady BAN 17 no.3:279-282 '64.

1. Biochemical Research Laboratory, Bulgarian Academy of Sciences.
Submitted by Academician A.I.HadJiolov [Khadzhiolov, A. I o].

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L

ACC NR, AP~O28~R7 :;CURCE CODE:

AUTIIOR: HadJiolov~A, A.; Tencheva, Z.

ORG: Biochemical Research Laboratory and Research Group of Nex~ology and Psychiatry,
Bulgarian Academ~ of Science
~ .

TITLe: A rapid detergent method for the isolation of cell nuclei from cat brain Cart,
SOURCE: Bulgarska akademtya na naukite. Doklady, v. 18. no. 1, 1965, 63-66

TOPIC TAGS: cell physiology, brain, cerebral cortex, experiment a~i,ml, protein
.!
ABSTRACT: ~nnglish article~ In the pest two years d{fferent detergents were:
succeSsfUlly employed in the isolation of cell nuclei from liver, ascitic
tumor cells (J. Zalte, R. Rozencwaig, N. Oeresso, P, Feverd,~ O. R. Aced, Sci.,
255, 1962, 412), HeLa cells (H. W. Fischer, H. Harris, Proc.~ Ro~v Soc., 156 B,
1962. 521), and . erythrocytea (B. R. A. O'Brien, J. Oell Biol., 20,
196~, 525). In the present work a procedure for the iaeiation of highly
purified cell nuclei from the brain cortex of adult cats by the use of the
nonionic~deter~ent - Cemulsol ~PT 12 (~'t~ do Produits Ohimiques de Synth~se~
Bezons, ~rence)and sucrose gradient centrifugation is described. According
to the obtained results, the application of detergents to the isolation of
brain cell nuclei is ~e.ry. usoik~l because of tho abundance .o[~...lipoprotoins~

Card,, ,1/2

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' - L 4367-66
ACC NR, ~..~.,~8]~ .~
! in nerv~"tissue. T'~e article describes ~he ~eolstion procedure,-the
!comparison of the action of different detergents (Cemuaol' NP~ /~, NP'r 8,
~ANPT 12, and Triton-X-lOO)s and the behavior o� brain ceil'nuclei dur�ng
sucrose gradient centrifuga%ion. Tho reoulta within a O.1 ~ sucrose_.~e4ium~
~hO~---thag'th'o-~r~in~h~ll nuclei ~ave-~"denaity ~ 2~"14'a~6rose... ..... a~ilar. ..t�~,
the density of nucle~ from other tiaouea.:.,' Th~ ~�ork ~as presented ~
19 Aug Sq.- Ac~l~dge-mn2s ~e"~ue '~o Or. H, Shopova ~d Dr,'E. ~ov for
tec~c~ ass~st~ce ~ 2o Dr. g. Tcha~ov for tal~ng 2he phase~ontra~ pict~es
of ~a~ oo~ex nuclei. Orig. art, has: 3 fi~es, 1 ~able' ~'

SUB CODE:

LS / SUBMDATE~

Cs~ 2/2

016

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� � i~ '~:~-',,~*~ ~',~ 't ~j:~!i: ~ ~ :i

CTA-RDP86-00513R000617810013-4

tlADJIOLOV, A.A.~ GENCHEV, D.; VENKOV, L.

Studies on the localization of oxidative phosphorylat~on in
cytoplasmic structures of rat liver. Dokl. Belg. akad. nauk
18 no.4~73-.376 ~65.

1o Suhnitted on December 14, 1%4.

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CTA-RDP86-00513R000617810013-4"

 "APPROVED FOR RELEASE: 09/17/2001
.'~!-';:' J ~:~!-T-J'~'~q~,.-'-~i!!J '~J:~l:-':� J i

CTA-RDP86-00513R000617810013-4

~ 156O4-66
ACC tm, A~60082~S $omcE CCI)g, ~/00~I6~/o~8100~/0373/0~76

AUTHOR,~--~.-*~-~~a~Ji�l�v' A..A~m.;.~ . Cenchev, D.; Venkov, ~. ~ I ~
CRG.' Central Eabaratary of Regeneration, Biochemical Research Laboratary,
Bulgarian Academ~ of Sciences

TITIE: Studies ~n the localization of oxidative phosphary]ation in cytoplasmic
structures of rat liver

SO~RCE~ Bulgarska akademtya na naukita. Doklady, v. 18, no. 4, ~965, ]73-3?6

TOPIC TAGS: rat, liver, biochem/stry, cytologY, phosphor~lation, heterocy~lio
base compound, organic phosphorus campound, cell physiolosy

ABSTRACT: It has been recently established by a number of authors
(See, e.g., D. E. Green, C__e~p. Biochem. Physiol., 4., 1962, 81; A.' E.
[ehninger et al., Ann. Rev. Biochgm., 31, 1962, 47) that ~tdati~
phosphorylation can be brought about by preparations off ~itochondrial
fragments. These inves%ig~%io~s re~uted the classical no%i~ns (O. Li~dberg et al.,
Chemistry a. Physiology of ~itochondrta a. Hioroecmes, Protoplasmatologia,
IILA, Springer, Wien, 195~, p. 136) that the proaess is necessarily associated

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,_ L 156O4-66
, AGG 1~: ~6008218

!with the intact'structure oS the mitochondria, The poaaibllit~ oP �~ide~[v~':
phosphoryl.~tion'being brou'~ht about by li~protein cinctures oF ~ lt~cture:
simpler th~n that o~ the mitoc~ndria re~eee the question o~ ~e~ ~e
other cellular ~embrane structures are not ~ a position'~o catalyze the
s~thesis of A~ coupled ~th ox~detion {A~- adenoetne~-triphoephate)e
B~n and Fe~leon (Exptl ~11, Rea,, ~, 1~, ~) ffound.that isolated
~crosomee o~ ~culer tissue are n�~ ~ a .~e~tion to brin~ a~ut
phoep~ryletion upon the addition 'o~ subsidies o~ the cycle o~
ec~ds. The~e results, ho~ver~ do not ~ve a ffinel anser ~o the ~eetion

' ~nsequen%l~, the preach% oxporimont8 ai~d m% invo=ti~tin~ the ~llibt'litiel
i.of phoaphoryletion of A~ to A~ In the o~oplas~c structures by using a ~r
suitable .substrata NAD.Ha (t~ - adenosine-~-diphoaphete{
~-nicotina~de~denine ~nucleotide in reduced ~orm). The ae~r~te
fractions ~re isolated from the liver of-alb~o rata. The reaults.obtainet
indicate thst o~dative phosphorylation ia connected ~t'h the ltpop~te~
:~mbrmnes in the inte~al zone of the mitochondrias the ao~mm of A~ to
acne ~in6 a limiting ~ctor ~ the rate o~ the process, He~ni~tions e~en
',,hen gone. ~..gt~$} .ce.~.e,. deat~yo .a pert of tho ~toahondrla and t~

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r. 15604-66
Icc NR ~ AP6008218

~'it~.~ondri'al -fr's~en~s obtained constitute impurities in the microeome
' �rec~ion, and this �act determines its apparent phoephorylativo activity. Pt
~,hould be pointed out that the absolute exclu~ion o~ the e~s2Oplas~c
� ~[~.popt, o~ membranes as the ~ite of ~-~ _ .
~axp~rimenta ~th exte~all ....... U~'~ve Ph�~~n ~- ~-

acede~ctamA. I, ~~' ~, __ ~F~'~-, 'f~ ~r vas suite'S- '
s~C~ ~ / S~MDA~, ~ / ~, 013 / S~s ~1

Card

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BULGA.~IA

HADJIOLOV, A. A., VE~�OV, P. V., DOLAPCIIIEV, L. B., Biochemical Research
Laboratory, %lhTg~a~ian Academy of Sciences

"Stepwise Degradation of Liver Ribosomal Ribonucletc Acids With Snake
Venom Phosphodtesteras~It

Sofia, pok,lad~ Bol~arskoy Akademti P