SCIENTIFIC ABSTRACT PELKA, Z. - PELKIS, P.S.

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• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001239910010-5
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: June 15, 2000
• Sequence Number: 10
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

o2l"q 008/004/o06/010
50/
303
%bigaie'w
Pe
10 6j)7_rI 24
oatenOldal .she I U00 41 196 9 conve% c"enoidal
'rlTL'B 9 TLOZpravY 'nz'ynl erskie, for the urvesi lying
tbe stress a ,Other.. -Both C shell for
per Provides cateuary along f,M a tY anslational
This pal ving one rtical lanesi (1.1)
btained by Oacular ve
shell Oally perpolld'
in UAW
*hi ch + in the state
'2 M 1) considered IS
(C - .2
z + The shell diaybragal!
curve, suPporte'd by riSlu to t1neir
dicular
of the be perpen horizontal
the parameter assumed to ctio! vbose niforw
d is the dire sbelli d on by a u'
where 'a tres ,g an forces 3.U t of the
of' membr ane sf a - i el eme" the shell acte
g riLca -
t tran e ;:=e t derea for
vi I I r, bdo Do Canal
Planes. a square,
forms
pro 3e
1' ard 1/3
28259
1)/006/6D '/008/004/006/010
D265/1)3D3
cateno-O&I shell equili-
ali.dfor a constant thickness shell under its Ovn Veight. The
load, . I in the elliptical- form
obtained
brium is 2 (),7)
F
+ ch --2
ch
m
by
per unit.
sents tile loading
is the stress function and z repre
of solution by numeri-
whe re he funicular polygon method the ele-
rojected areso T
Of the P y dividing the projected square of
ICal calculations is provided b obtaining the system of 15 equationsg
al squares and
zental shell into 10 equ valuess of each of the constituent parts of these
for mbich the corresponding normal and tangential forces are determined
ated,, The ge from the -values of stress func-
equations are tabul
a the paBsft
and tbe inverse matri'% permit
tions,F i to those of the second derivatives Pi 1 1. The distributirin Of
4u- enrners of the shell is Considered and their
nrtlvzed. The

9
ALIKSIV, N.; PILKIN, B.: NICHEY, V.; TODOROV, V.
Problem of therapeutic physical culture in pulnonary tuberculosis.
Suvrem. mod., Sofia 7 no.12:113-121 1956.
16 Is Naucbnolzoledovatelskiia institut po tuberkuloza (Direktor:
Dots. St. Todorov).
(TUBBRCULOSIS, PUMNARY, therapy,
exercise ther..(Bul))
(RXWCISM THILUT, in var. die.
pulm-tuberc. (Bul))

----------
MITU, Hulk,.
ti,~,-
Ovarian function in pulmonary taberculosis. G"k, gp. 22[371 no-112;
90-93 Jan 58.
1. For.-gy-n. klinika pri VMI v Sofii, prednosta , of. Dr G. 7osev
Pr
VUTbc v SoM, prednosta Dr T. Sarkov. Prelozil ba. Mr A. Xotaneks
Praha 2, Aplinarnka 18.
(TUBMMMIS. PUIXOMY, C0=1.
inenatruation disords (Gz))
(MMSTRUATION DISORIMES, in var. dis,
tubere., pulm. ((;z))

PWAIN, Spas
Artificial pnemmothorax theraW [with s=ary in French]. Probl.tub.
nool:72-75 159- (MIRA 12:2)
1. Nawbmyy sotrudn!Lk tuberkulasnogo inatitutit (Sofiya), chlen
bolgarokoy meditsinskogy gruppv Krasnogo kresta v Koreye.
(PNMOTHORAX, ARTIFICIAL.
result statiet..(Rus))

:DZHUROIf , G. ; PELKIN, Sp.
larly result a of the treatment of chronic disseminated tuberculosis of
the lung with tubigal; preliminary communication. Suvrem.med., Sofia
6 no.8r19-25 1955.
1. Ix NauabnD-isaledovatelskila institut po tuberkuloza - Sofiia.
(direktor: dots. St.Todorov)
(THIOSIKICARBAZONES therapeutic use,
tubigal in pulm.iuberc.)
(TUBIRCUWSIS, PULMONARY, therapy,
thiosemicarbazone tubigal)

KELEYNIKOV, Yuolaaj polkovnikj voyennyv letchik pervogo klasua; SOKOLOV, V.D.,
podpolkovnikj STEPANENKO, P.L., mayor; REBROV, M.I?.p 'Inzh.-kapitan;
PELIKINY V.F4 starshiy leytenant, voyenny7 letchik vtorogo klassa
I---------- ~J
Flight day. Vest.Vodz.Fl. no.12:1-20 D 160. (MIU 14:5)
(Flight training)

FELIETNA L.,.Askufjstvaved
Discussion of pictoria.1 arts (to be con-Unued). Ilauka i
zbyttia 12 no.12t4O-a D 162. (MIRA 16:8)

A 0`4
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-00
was I-Ittki. by 1wifl-
action of an tquiluol, "list. of Allyl brutulde Sid crultin.
atdchydt vrith Me. The yield of ale. was &)%, It Its, 1111111
418-4CV, 11V UAW, A cmpd. covirviodin to sell
oe ji Coll&,Opwuobtattwdbyintewtional(Ph 1XIII.C0
and allyl bromide whb Allf. The compd. m. Wt' fuld has
3 douW bomb and Wouic ptoWrtkx. Steg"ise bm-
aes
00' alinatiou indicates great activity ot one of t1w 3 double
bmiN, PrIAMMY thir atlVI. Z. Kaltficil
41
it
Of#
tsI
us
11 NOW I L11111CA11
---ifii 0-1-aw'wpwW-i NJ gas
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1 0
0
0-9-9 40 10 , 1 0 a 0

P.S.; MPKC),, L.S.
Research ln the f lold of thlocarbazone substituted derivatlyes.
Part 1. Ditolylthiecarbazones. M-,r.khim.zhur.17 no-1:93 -102
151m (KLRA 9:9)
1.1notitut organichaskey khimil AkRdemil nau): l3krainskey SSR.
(Thi6earbazone)
"NU

Iladimir Folikarpovich lAvorskii; on the 10th anniverawy of his
Ceath, Ukr4,W.m.shur. 19 noolt3-20 133. (MM 714)
I. Inetitut orgudc,heakey khimli Akademii nauk USSIL.
(Chem!Lstry, Organic) (Uvorelkli, Toi0dj;iir P~iykarpovych,
1817&1942)

PTI K13) P~:&
Zfcel'kh' DoWify-Alad. Ta uk .5.3=. 86, ON-1002
having an absarp-
U) am endhial (M) forms, the former
AneWimalar
mixt. of I and Mel in alkali yielded the Me dei*., m. 122-3%
9bring pink Was. in org. solvenLq and having max. at 545
and 430 rup, Indicating a mixt. of S-Me and N-Mc derivi.
Cuomatographle sepa. an AIA in petr. ether, followed by.
y1ilded-thic-2 forins: red, m. 116~17% dt-
Oymp. 127-8% max. 430 miA, and brown, tit. 1241'. triax.
A45 mis. From the absmption max. data, the tatter It the
It-Me. the former the S-Me deriv. The N-Me forms pames
bito the &Me form in vari;otm solvents (curve In C411s at
IS* Is shown), the reaction bein; complete in C411a In 20 his.
11 and M cmild not be sepd. in this manneri M is pre-
ilominant In MeOll soins., which am yellow and show max.
40 mp. In MeOlf I forms metal complexes and with al.
Imiles gives a red color. Addn. of C4Hs to such solos. Xives a
col characteristic of U, and the soln. shows m-.
rh%Od 6'20 mp; the latter probably arises from destruc.
lition of the H-bouded complex with I&OH. Protophilic
.3o1vttrits affect the max. of I soIns. Thc45OandGWtnp
max. we seen In hexane. CsIls, and CCJ,; in CUM,. they
Ire 443 and 610, In MejCO, they air 450 and 640; In PrOHI
450 mul 600; In MeOU, 470 and 620, In MeNO,, 440; and
IUHCONHI,460. Absorption max. ofanalopof I, di-oAolyl
_V3AX,470and632InW#- dl*toIyl4(15and63O; di-m-tolyl
465 and 636; &P-xenyf 480 and M; di-2-maphthyl 602;
and &I-rutphthyj W. Derivs. whose short wavo max, Is
feeble am has W. In aq. alkall and foon metal complexes at
hi her H I vels The naphthyl derivs are haw. even In
OR Zal.' G: M. Kosolapoq.'~
J

KIMANOV, A.I.; B&BICHRY, F.S.; MUSHKALO, L.K.; POCRIBIOX. Y.Ta.; YELIKIS.P.S.
(Omtline history of organic chemistry at Kiev University] Ocharki po
istorii organichaskoi khimii v Kievokom univerattete. Pod red. A.1.
Kiprianova..[Kiev) Izd-vo Kievskogo goo. nuiv. lm. T.G.Sheveheako,
1954. 130 P. (MLRA 9:8)
(Chemistry, Organic) (KisvVniversity-)

ar&~ 3~
-Piib.- 151~:7m~ 32142

loth s ;P,
jtki

E Pear azone:Fsubstitutes SynthOsis and study of properties
itudj.!of. thi b
o norisymmetrical thi6lzarbazone,derivativea,

4~_ -1954
Zhur. 'ob.. khim. - 24/9 _160-1645,~Sep

lems.': Of --Aeth~~ -a~nd ymwt~lc~i thiocarbazon~s readt
h&d: non
prob

ry is reflect-
_A~dth 4ifferent . dationtj,.how ths,'disturban 66 in-- the s-ynne
the nature: of . tl4ocarbazona absorption curve 6 and how,stable

new method
thi6c6rbawnez are aga st oxidation ware'investigated A
9~ - I -
nes-with two different aryls was
for the.derivati.6n oflithiocarbazo
Vitfi-thg~.new method are de5a~ribed.
-'de'veloped. Some ivs4ts.dbtain6d~
-19 Table; graphs.'
ference 4-USA 4--Germn and 24S~Wlt (1878- 53)
'Ten re 8
jj
itui ion laa&,, of Sc. Ukr--SSR Institute of-: Organid, Chemistry
-Marrah- 954--:-

yl

rw~7

:A44
-.i u r t of in t :n
~7-.

AUTE'OR; Pellkisj P.. S. and Dubenko, R. G. 73-1-10/26
4 . .....................
TITIR: Photochemical Isomerization of Methylated Derivatives
of Dithizon and Its Substitute. (FotokhJmicheslmya
Izomerizatiatya blatilirovannykh Proizvoclx~ykh DitizoAa
i Yego Zam)shchennykh.)
FERIODIOAL; Ukrainaldy 1(himialleakiy Zhurnal, 19!1?, Vol.23, No.1,
pp. 64 - W (USSR).
ABJEOTFACT: In previous communications it was. showa that the
yellow metbylatlon products of dithizone and of its
derivatives can be considered as the cis-cis-isomers
(fonula I) and the violet-ooloured products as the
trani3a-txans isomers (formula 11). (viz. Refs. 1,2).
Their sensitivity to lightwas observed as well as their
capacity of inter-isomexisation the velocity of which
Idepe:ads on the liGht-and on other facto:vs. The authors
have now investigated the velocit7 of isomerisation of
trans-isomers of 8-methyl derivatives ot dithizone and
and of the eis-isomer of S-methyl derivatives of di-
(o-tolyl)-.thioearbazole in benzene under the influence
of sunligt_,t and of artificial light, also in the presence
of a pyrie1ine catalyst. Kinetic curves of the velocity
of isomerisation can be described by the monomolecular
Card 1/2 law. The velocity of isomerisELtion of -the cis-isomer

?5-1-10/26
Photochemical IBomerization of Methylated Derivatives of Dithizon
and Its Substitute,.
of the S-methyl derivative of di-(o-tolyl)thiocarbazole
into the trans-isomer exceeds the velocity cf! isomeri-
sation of the trans-S-mathyl derivative of d-.thizone
to the cis-isomer considerably. Table 1 givas the
analytical data of the synthesised derivatives of
dithizoneo QTraphs showing the velocities of isomeri-
sation (graph 1 - 6) are included. There are 6 graphs,
4 tables and 3 references, 2 of which are Slavic.
SUMUTTED: July, .11, 19560
ASSOCLLTION: institute of- Organio Ohemist.ry., Mademy of Sciences,,
Ukrainian SSR. (Institut Organicheskoy Xhimii Ai~ U~SR).
AVAIIABIZ: Libr=7 of Congress
Card 2/2

AUTHOR: Pellkis, P. S..and ~Dubenko, R. G. 73-1-11/26
TITIZ : _fs_~omerio'Vransformations of Benzyl Derivptives off
Dithizone and Its Substitutes. (IzomernWe Pre vrashcheni a
Benzillnykla. Proizvodnykh Divizona, i Yego Zcme~hchennykh.~
11E'RICD1CAL-. Ukrainski-y Xhimicheski-y Zhumal, 1,95?, Vol.23, No.1,
pp- 69 - ?i (USSR).
ABSTILOT: It was found that dur:Lu the methylation of dithizone
and its substitutes yellow cis-cis- and violet trans-
trans-isomers of S-methyl derivatives were formed
(Refs. 1 - 3). The benzyl derivative of dithizone,l,
5-di-(O-tolYl)- and 1,5-di-(o-plienoxyphenyl)-tbiocarbazole
were eynthesised. The synthesis-3d be:.azyl derivatives
are shown to underE;o isomeric transfomation under the
influence of light. In an analogous way to the methyl
derivatives of dithizone it follows that the violet-
coloured benzyl derivatives are the trans-trans- isomers
whereas the yellow-coloured derivatives represent the
cis-cis-isomeric forms. Analytical data of monobenzyl
derivatives of dithizone and of 2 substituents are given
in tabla 1. Absorption curves of the compounds in
benzene are given in r~mpha 1 and 21 tho volooity of
isomerisation in benzene is given in.graphs 3 and 4.
-There Are I table, 4 graphs and 3 references, all of whieb

?3-1-11/26
asomeric, Transfomp.tions of Benzyl Derivatives of Dithizone
-and its Substitutes.
are Slavic.
SUMITTEID: July, 11, 1956.
ASSOCIATION: Institute of.Organic Chemlebry.. Academy of Sciences,
Ukrainian SSR. (Institut Organicheskoy Khimii AN USSR.)
AVAILABUR: Library, of Congress
Card 2/2

PSLIXIS, P.S.; DUIMNKO, R.G.
Investigations in the field of substituted arylthiocarbazones.
Effect of the solvent on the tautomeric equilibrium of arylthio-
carbazones. Ukr. khim. zh-jr. 23 no.6:748-753 157. (MIRA 11:1)
1.1natitut organichoskoy khimii AN USSR.
(Solution (Chemistry))
(Tautomerism) (Carbazone)

PELIKIS, P.S.; DMFKO, R.G.; PUPKO, L.S.
Investigations in the field of substituted arylthlocarbaz 'ones.
Resistance of 1,5-diphenylthiocarbazone and its substitutes to
oxidation. Ukr.khim. zhur. 23 no.6:754-756 157. (MMA 11:1)
1w,1xts.titut organicheskoy khivdi AN USSR.
(Dithizone) (Oxidation)

DUBIANKO, R.G.; PMO, L.S.
Studies In the field of substituted i,5-diplienylthiocarbazone.
Part 6:- Synthealaand itudy of the propertios of mono- and
'~5
dihalide substituted 1, -diphopylthiocarbascine. Zhur. ob. khim.
27 no-8:2134-2l3a..Ag (MIRA 10:9)
1. Institut organicheakoy khimii Akademii neuk Ukraiuskay SSR.
(Xihizone)

PMO, L.S.- PELIKIS,
Reduction clearage of una7mmetrical derivatives of 1.5--&iphen7l-
thiocarbazone. Ukr. khim. sbur. 24 no.4:477-WO 158,
(miu 11:10)
1. Institut organichnskoy khimii AN USSR.
(Dithiasons) (Reduction. Chemical)

AFTHORS
TITLE;
PERIODICAL:
ABSTRACT;
Card 1/3
~~DT/ 2o-12o-2-26163
Fellkiop P. B., Dubenko~ R. G.
An Investigation of the Solvent's Influence Upon the
Position of Tautomeric Equilibrium in the Arylthiocarbazone
Series (lasledovaniye vliyaniya rastvoritalya na polozheniye
tautomernogo ravnovesiya v ryadu ariltiokarbazonov)
Doklady Akademii Nauk SSSR, 1958, V-31- 12o, Nr 2, pp.32o-322
(USSR)
This influence is generally known, 'but many problems of the
theory of this phenomenon are undetermined, although much
has already been achieved. (Refs 1 - lo). A survey on this
is given (Refs 1. 6, lo - 12). The first author proved
(Ref. 13) that 1,~-diphenyl-thiocarbazone (dithizone) in solv-
ents represents a tautomeric mixture of thione (a) and
thiol (b). The interrelation between the thione- and the
thiol-form in the tautomeric mixture depends on the nature
of the solvent and of the substituent in the aromatic nuclei
of thiocarbazone. The maxima at the absorption cu~rves of
the substituents of 1,5-di.plienyl-thiocarbazone in the short-

2o-1 2o-.2-26/63
An Investigation of the Solvent's Influence Upon the Position of Tautomeric
R'quilibrium in the heylthiocarbazone Series
-wave range belong to the thiol-forms, whereas the maxima
in the long-wave range belong to the thione-forms. From this
the constant of tautomeric equilibrLum is derived. As the
experimental data show this constant of dithizone and its
substituents in solvents is approximately equal to the ratio
dA max2/dx maxi. The ratio Elft 2 ie practically independent
of the solvent and is approximately = 1; thus the second term
of the sum of equation (2) may be dioregarded. Table I gives
the data concerning the determination of the constants of
tautomeric, equilibrium of the 3 thiocarbazones in different
solvents. Table 2 gives the absorption maxima for the investi-
gated thiocarbazones and the corresponding optical densities
as well as their ratio. As is to be seen from table 2 and
figure I the linear nature of dependence and the inclination
angle of the straight line (450) is quite satisfactorily ob-
oerved. It can therefore be stated that the relation derived
by 11. 1. Kabachnik which extends the rules governing the
acid-basic protolytical equilibrium to the ketonal equilibrium
io in the arylearbazone series confirmed for the tautomeric
Card 2/3 thione-thiol equilibrium. There are 'I figure, 2 tables, and

SCV/ 2o-12o-2-26163
An Investigation of the Solvent's Influence UpozL -the Position of Tautomeric
.Equilibrium in the Arylthiocarbazone Series
16 references, 14 of which are Soviet.
ASSOCIATION:- Institut orgaixicheakoy,khimii Akademii nauk USSR
(Institute of Organic Chemistry
,,AS UkrairtLan S~R)
PRESSNTED: December 27, 1957, by B. A. Kaaanakiy, Member, Academy of
Sciences, USSR
SUBm*rTTED: September 27, 11:955
11 cyclic compounds--Properties 2. Sollrents--Chemical reactions
3. AcId-base equilibrium-Mathwatical. analysis
Card 313

AUTHDRS: Pellkisq F. S., Dubenko, R. G. SOV/79-29-1-41/74
TITLE: Investigations in tho Field of Substitution Products of
1,5-Diphenyl Thiocarbazone (Is-,-ledovaniya v oblasti
tameshchennykh 1,5-difeniltiokarbazona) VII.Influence of
the Nature of the Subst-ituents in Phenyl Nuclei of 1,5-
Diphenyl Thiocarbazone on Thione-Thiol Tautomery (VII.
Vliyaniye prirody zamestiteley v fenillnykh yadrakh 1,5-di-
feniltiokarbazona na tion~tiollnoye tautomernoye ravnove-
siye)
PERIODICAL: Zhurnal obshchey khimii, 1959, Vol 29, Hr 1,
PP 194 - 197 (USSR) '. -
ABSTRACT: Many investigations have been carried out dealing with the
problem of dependence of Iceto-enol tautomery on the
of the compounds ca'pable of tautomery; few, how-
the field of thione-thiol,tautomery~ In this
'~.Conneqtio'n no attention,at-all was paid to aryl thiocarba-
zones. It was therefore interesting to inveotigate the
influence of the substituents in the phonyl nuclei of aryl
thiocarbazones which is exercised upon thione-thiol tauto-
Card 1/3 mery in the solution.- The synthesis of aryl thiocarbazones

SOV/70-29-1-41/74
Iiveotigat-ions in the Field of Substitution Products of
5-4liphenyl Thi6carbazone. 711. Influence of the Eature of the Sub-
stituents in Phenyl Nuclei of 1,5-Diphenyl Thiocai,,basmne on the Thione-
Thiol Tautomery
~was already earlier describe8"-(Refs 3,4). The table scows
t -investigation of aryl thio-
the:data of, spectrophotome ric
carbazone-s. From these'daia the conclusion can be drawn
that in the casl~~-6f thiocarbazoneft with nucleophilic sub-
~tituents i the phenyl nuclei-the extinction of the
s n
Maximum in the short-wave range is equal or higher as
compared to the maximum in the long-wave range (prepara-
ti-ons Nr 13-32)b In the case of thiocarbazones with electro-
philic substituents in-the phenyl nuclei the extinction of
the maximum in the.short-f-wave range is enual or higher as
compared to the maximum in the lang wave ranCe (prepara-
tions.Nr.:.1-12). This,is illustrated in detail in fi-ure 1.
Also further investigations showed that the electrophilic
substituento in the phenyl nucleus of 195-diphenyl thio-
carbazone have the same influence upon the relation between
thione- and thiol forms of thiocarbazones as the polar
solvents (methyl alcohol, formamide and others)(Ref 1).
Card 2/13 Thus, 36 substitution products of' 1,5-diphenyl thiocarbazone

Investigations in the Field of Substitution ?roduc:ts of SOV/79-29-1-41/74
v
ence of the Nature of t,,e Substituent
1,5-Iliphenyl Thiocarbazone. VII. Influ t, - s
in Phenyl Nuclei of 195-Diphenyl Thiocarbazone ~,~on the Thione-Thiol Tauto-
mery:
were spectrophotometrically investigated; summarizing it
was shown that the electrophilic substituents shift the
tautomeric equilibrium of the thione- and thiol form in
the substituents of 1,5-diphenyl thiocarbazone towards the
side of the thiol form. There are 2 figures, 1 table, and
5 referencesi 4 of which are Soviet.
ASSOCIATION: Institut organicheskoy khimii Akademii nauk Ukrainskoy SSR
(Institute for Organic Chemistry of' the Acade,-ny of Sciences,
Ukr M)
SUBMITTED:- -0~tober 9, 1957
Card 3/3

AUTHOAS: Dubenko, R. G., Pellkis, F. S. SOV/79-29-1-42/74
TITLE- Investigations in the Series of the Substitution Products
5-Oxy-2,3-Diphenyltetrazolium Betaines (Issledovaniya v
ryadu zameshchennykh 5-oksi-2,3-difenil-tetrazoliy-betaina)
PERIODICAL: Zhurnal obahchey khimii, 1959, Vol 29, Nr 1,
PP 197 - ?00 (USSR)
ABSTRACT: a. receent yeara q%m4.axTAry e="1=
derivatives . as inert. soaps have jwea investigated and also
tested with respect to their bactericidal properties (Ref 1).
In this connection the authors investigated various com-
pounds of tetrazolium. On the synthesis of aryl thiocarbazone
according to the formazyl method (Refs 2,3) they obtained
as intermediate products various substituted products of
1,5-diphenyl-3-nitroformazane. According to Pechmann and
Runge (Ref 4) such formazyl compounds can be transformed into
corresponding derivatives of tetra,,olium or into the betaine-
like compounds in the case of oxidation (Ref 5) according
to the scheme:
Card 1/3

Investigations in the Series of the Substitution Products 307/79-29-1-12/74
5-Oxy-2,3-Diphanyltetrazolium Betaines
N-NR N=NR
02N-C +CH3coon --) HO-C +CH3ONO2 0
N-NHR + N-NHR
IIT-IjR N=IIR
--4 C or U-c ............I
The best way for the oxidation or cyclodebydrogenation,
apart from the yellow mercury oxide or amyl nitrite in an
alcohol solution with hydrochloric acId (Ref 4) is to use
lead tetraacetate in chloroform (Ref 1). According to
Wedekind, Stauve the tendency of the substituted formazyl
derivatives to close the tetrazole cycle depends on the
nature of the substituents in position 3. Bamberger and
collaborators cyclodehydrogenated 1,5-diphenyl-3-nitro-
Card 2/3 formazane by heating in acetic acid in the presence of

Investigations in the Series of the Sub--titution Products BOV/79-29-1-42/74
.5-0:ry-2,3-Diplienyltetrazolium Betaines
amyl nitrite, in which case an acidolysis of the nitro
group takes place with subsequent oxidation of nitro
formazane to tetrazolium derivative (Ref 7)- Under the same
conditions the authors carried out the oyolbdehydrogenation
of 9 different oubatitution prodtacl.s of 1,5-diphonyl-3-
nitro formazane. in this connection they succeeded in the
cyclodehydrogenation in good yield of the meta- and para-
substituted derivatives to the derJ~'.vaatives of tetrazolium;
which is not the case with the ortho-substitution products.,
The table shows the synthesized substitution products of
5-oxy-2,3-diphenyltetrazolium betaines with the general
formula (1). They are of a crystalline natitre. Their ab-
sorption spectra were investigated. There are 1 figure, I
table, and 7 referencest 2 of which are Soviet.
ASSOCIATION: Institut organicheskoy khimii Akademii nauk Ukrainskoy SSR
(Institute fo-- Organib'Chemistry of' the Academy of Sciences,
Ukr SSR)
SUBM:rTTED: October 9, 1957
Card 3/3

AUTHORS: Dubetnko, R. G~, Pellkis, P. S. SOV/79-29-2-17/71
TITLE: Investigation of Aryl Thiocarbazones Methylated on Sulphur
(lealedovaniye metilirovannykh po sere ariltiokarbazonov)
PERIODICAL; Zhurnal obshchey khimii5 1959, Vol 29, Nr 2, PP 435-437 (USSR)
ABSTRIXT: In follow-up to their previous papers (Refs 1,2,3) the authors
wanted to investigate on further compounds the influence exerted
by the nature of substituents upon the formatior of the cis or
traaa-form of the methylated aryl thiocarbazone derivatives.
S-methyl derivatives were synthesized as follows: equimolecular
quantities of aryl thiocarbazone and methyl iodide were inter-
mixed in aloohol alkali medium at low temperature and the mix-
ture was left standing for a few homrs. The methyl derivatives,
separated in good crystals and puriTi-ed overnight, were analyzed
and investigated by spectrum analysis. Some of them were also
subjected to chromatography in colixwiawith aluminum oxid4
(Table). The yields In S-methyl derivatives given by aryl thio-
.carbazones we--re good, All preparations have but one absorption
maximums As already shown earlier, S-methyl derivatives of aryl
thiocarbazones with the maximum in the short-wave range 420-
Card 1/2 470 me are cis-isomers2 whereas those having the maximum in the

SOV/79-29-2-17r/7i
Investigation of Aryl Thiccarbazones Methylated on !Julphur
530-570 mp range are trap-8-isomers. As can be observed from the
tabulated spectral photometric data covering ten derivatives and
three that had been earlier investigated (Ref 1), five of them
give cis-derivativee, compounds, with orthosubstituents and
trans-derivatives with substituents in the para-position. Cis-
isomers rapidly &Eomerize into the trans-forms under the in-
fluenoe of sunlight, The figure shows the absorption curves of
the cls and l.-rans-forma rif, S-methylated derivati-eFi of I 5-di-
(2-bromophery!) and 1,5-di-(,^~.-anisyl).-+.hiocarbazorie and their ab-
sorption curves after a 30-minute eXD05ure in, scattered sian-
light. There are I figure, 1P table, and 3 Soviet references.
ASSOCIATION: Inatitut organicheskoy khimii Akademii nauk Ukrainskoy SSR
(Instlitute of Organic Chemistry of the Academy of Sciences,
Ukrainakaya SSR)
SUBMITTED: November 16, 1957;
Card 2/2

MAIS: Dubenkoj R. G.f Pellkis, P. S. SOV179-29-3-20161

TITLE: Investigations in the Series of Thiocarbanilide Derivatives
(Iseledovaniya v ryadu proizvodnykh tiolcarbanilida).
I. Synthesis of the Sulfamide-, Carboxy'.-, and Sulfo-substi-
tuted Compounds (I. Sintez sullfamido-, karboksi-) i sullfo-
zameshchennykh)
PERIDDICAL; Zhurnal obshchey khimiip 1959, Vol 29, Xr 3, pp 885-887 (USSR)
ABSTRACT: In the last years many different thiourea derivatives were
synthesized and investigated as to their antibacterial and
specific tuberculostatic qualitites (Refs 1-6). Among the
thiourea derivatives the sulfonamide derivatives and the carb-
oxy-substituted derivatives are little investigated. The aim
of the present paper was to fill this gap. The diaryl thio-
urea derivatives were obtained according to the following
three methods: S
1) 2 RNH2 + CS2 51- RNH8NHR + H
S
2
S
Card 1/2 2) 2 HIM2 + CS 2+j2+2 C6H5NRNHCIIHFL + 2 05H5N.HJ + S

Investigations in the Series of Thiocarbanilide SOV/79-29-3-28/61
Derivativas. 1. Synthenis of the Sulfamide-, Carboxy -,, and Sulfo-substituted
Compounds S
3) 2 RITH2+ CS2 RITHCNHR + H2S.
The best and most convenient method of synthesizing the sub-
stituted aryl thioureas.proved to be tbgt which is based on
the corresponding ainines and carbon dis-alfide in the presence
of sulfur (Ref 7). The 11 aryl thiocarbamilides synthesized
are listed in the table, nine of which beine; new. As may be
seen the yields are high. They are of crystalline nature.
The figure gives the absorption spectra of the alcoholic solu-
tions of five thiocarbanilides in ultraviolet. There are 1
figure, I table, and 8 references, I of which is Soviet.
ASSOCIATION:
SU13MITTED:
Card. 2/2
Institut organicheskoy khimii Akademii nauk Ukrainskoy SSR
(Institute of Organic Chemistry of the Academy of Sciences,
Ukrainskaya SSR)
November 18, 1957

RM
DUBEIZO, R.G.; PZLIKIS. P.S..; SHEKA, I.A,
Dipole moments of some S-methyl derivatives of arylthiocarbazones.
Ukr.khtm.zhur. 26 no.1:48-52 '60. (MM 13:5)
1. Institut organicheskoy khimii AN 'USSR, Insti-but obahchey i
neorganicheskoy khimii AN USSR.
(Carbazonie-'Dipole moments)
t' E

LIKIS, P.S.; PIRETYJZRW, M.Z.
Synthesis and study of the properties of carboxy- and oulfonamide-
substituted derivatives of 1,4-diphenylthiosemicai-bazide. Ukr.
khim. zhur. 26, no.5:637-640 160. (MM 13:11)
1. Institut organicheakoy khimii AN USSR.
(Somicarbazide)

IDUO
Substituted aryl hydrazones of phenylglyoxyloyl chloride. Z'---=.
obvkhirao 35 no*12;39:L7-3920 D 163. (MRA 17:3)
1. Institut organicheakoy khimii AN UkrSSR.

Rsylllovp Ye.P.; PELIKIS, P.S,.
Synthesis of p-nitrophenyl eaters of substituted carbamic acids.
Zhur. ob. khim. 34 no.10:3467-3469 0 164.
Synthesis of ures, derivatives. Ibid.*.3469-3473
(MIRA 17:11)
1. Institut organicheskoy khimii AV UkrSSR.

PWTYAZHKO, M.Z.; PELIKIS, P.S.
Synthesis of substituted 1,4-dipbenylthiosemicarbazides and
their cyclization to 2,3-diaryl-5-arylamiho-l,),4-thiodiazolines.
Zhur. ob. k1him. 34 no.10:3484-3486 0 164.
(MIRA 17:11)
1. Institut organichaskoy khimii AN UkrSSR.

DI]BnKO, R.G.; GORBXW,
Synthesis of unsynmetrical derivatives of thiocarbanilide. Mr.
khim. zhur. 26 no.5:641-643 160. (MIRA 13:13.)
1. lustitut orjm*icheskoy khimli AN USSR.
'T(Car-banilide)

8/079/60/030/05/08/074
B005/BO02
AUTHORSt Dubenko, R. G.,p Pellkis, P. S.
TITLI:h Investigations of Asymmetric Derivatives of' 1,6-Diaryl
Hydrazodithiodicarbamides I
PERIODICAL: Zhurnal obahchey khimii, 19601 Vol, 30, No- 5P PP- 1437-1441
TEXTs The authors synthesized various asymmetric derivatives of 1j6-di-
Pbenyl hN,drazoditbiodicarbamideslwith the general formula RlqHCSNHNHGSMMI
by iray of the reaction of substituted 4-phenyl thiosem:~carbazides with
the correspondingly substituted phenyl isothiocyanatesjon boiling in
absolute alcohol. The scheme of this reaction is given.. The derivatives of
4-phenyl tbiosemicarbazide (general formulat - NIICSMH2) used as
initial products are given in Table 1. 18 deriva ves are specified
along with their melting points# yields in the production, gross formulas,
and nitrogen contents. These compounds were obtained by the reaction of
the correspondingly substituted phenyl isothiocyanates with hydrazine
hydrate in aqueous-alcoholio solution (Ref. 5). The substituted phenyl
.-Card 1/3

Investigations of Asymmetric Derivatives of S/079/60/030/05/08/074
1,6-Iii-aryl Hydrazodithiodicarbamides I B005/2002
isothiocyanates used as a second initial product were obtained from the
corresponding amines and thiophosgene in chloroform and. water as a medium
(Ref. 6). Two figures show the absorption. spectra of 6 derivatives of
4-phenyl thiosemicarbazide und of 8 derivatives of 1,6-diphenyl bydrazo
dithiodicarbamide in the ultraviolet range of the spectrum. The
were taken by means of a spectrophotometer of type C~-4 (SF-4)I,-`with the
substances being in alcoholic solution. Table 2 shows th1i'y6yiffietric
derivatives of Ip6-diphenyl hydrazo dithiodicarbamide synthesized by the
authors. Wderivatives are mentioned along with their yields, melting
points, gross formulae, and nitrogen contents. All of the syntheses car-
ried out are described in an experimental part. Among other things, a
description is also given of' the procedure of synthesizing certain
substituted phenyl isothiooyanatesq that have heretofore not been de-
scribed in publications. There are 3 figures, 2 tables, and 6 non-Soviet
references.
Card 2/3

Invelltigations~of.Asymmetric Derivatives of 9/079/60/030/05/0B/074
lj6-Diar;yl Hydraz.odithiodicarbamides I B005/BO02
ASSOOIATIOR: Institut organicheskoy khimii Akademii nauk Ukrainskoy SSR'
(Institute of Organic Chemistry of the Academy of Sdiences of the
~~raln--a-Raya SSR)
SUBMXTTEDs March 26, 1959
Card -3/3

LO,",INSKIY., M.O.;_LELIKII, P.S.
Syl*Jmsis of some symetrical derivatives of 1..5-diphey-71-3-chl-
oroformazan. Ukr.khim.zhur. 27 no.5:667-669 1161. (MW- 14:9)
1. Institut organichaskoy khimii AN USSR.
(Formazan)

MUM, R.G,; PELIKIS P.S.
Symetrical derivatives of 1,,6-diarylhydrazod.ithiodicarbo namide.
Ukr.khim.2hur. 27 no.5:669-671 161. (MIRA 14.9)
1. Institut organicheskoy khimii AN USSR.
(Amides) (Carbonic acid)

R.G.-.;,PBL! aS, P.
Inv4stigation of derivatives of thiccarbanilidle. Part 1:
Synthesis of asymmetric dihalide derivatives of tbiocarbanilide.
Ukr.khim.zhur. 27 no.5:673-675 161. (14IRA 14:9)
1. Institut organicheskoy khimii All USSR.
(Carbanilide)

LOZINSKly,- M.O. [Lozynalky-I., M.O. 1; PELIKIS, F.S.
On the synthesis of arylazochlora~etie acids. Dop.All URSR
no,/#*.508-510 161. (MIRA'-14-.6)
I* Institut organichaskoy khimii AN USSR. Predstavleno ak-ademikom
AN USSR A.I. Kiprianovym,
(Acetic acid)

FEM,TYAMIKO, M.Z.; PELIKIS, P.S.
Dynthesis of 2t3-diaryl-5~-arylamino-1,3,4-thiodia2o:Lins. Ukr.khim.
mhur. 30 no.2t206-208 164. (KMA 1734)
L Institut organiobeekoy khimii AN UkrSSR,

DUBENKO, R.G.; TANCMZ, Yu.V.; PELIKIS, P.S.
Synthesisand study 6f'derivativeis ot trimthyloinetrisulfone. Part Is
2,4p6-TriarylhydrazmN.of trimathylen*a-l 1~5-trisulfonoi Zhur.ob.khim.
34 no.2v682-684 F 164. 1 p (MIRA 170)
1. Inatitut organichaskoy khimii AN UkrSSR.
.T R~

- DUBENKO, R.G.; GORBENKO, Ye.F.; PELIKIS, P,S.
Synthesis of certaiii-formazans with carbohycb-ate residue.
Zhur. ob. khim. 31 no.3:883-885 Mr 161. (HM 14:3)
1. Institut organicheskoy khimii AN USSR.
(Formazans)

LOZINSKII, M.O.; PELIKIS, P.S.
I., 5-Diaryl-3-haloformazan series, Part 2: Syathesis of ary-lazo-
chloracetic acids. Zh-dr.ob.khims 31 no*5:1621-i624 my ,6i.
(KMA 34:5.)
1, Institut organicheskoy khJmJi Akademii nauk Ukrainakoy SSR.
(Acetic acid) (Formazans)

DUIENKO, RG.; Pl,',LIKB, P.S.
Synthesis of the Wogep-substituted asymetric derivatives of 1,6-
diphon.vlbydrazodithiodicarbonami.tio, Part 4& Zhur.ob..khim. 31 no.5:
1661-1663 my 161. (KIRA 14:5)
1. Institut organicheskoy khimii Akademii nauk Ukrainskoy' SSR.
(Carbonamides)

DUBERK,Dj, RiG.~_MLIKIMq F.S.
Synthesis of as7=stric alkoxv-substituted 1, 6-dipherry2hydrazo-
dithiodicarbonamide. Part 2. Zhuroobokhims, -3,1 no*6:2045-2049
~204191
je i 61. (MMA 14:6)
1e Institut organicheakoy kbJmJJ AN Ukrainakoir M.
(Amides)
U.

MUMMA A.D.; PELIKIS., P.S.
Substituted arylalaides of ditbiocarboxylic acidn. Part 2:
Synthesis of halo-)..sulfo-,., and carboxy-B-pheny:Ldithiooxamides.
Zhur.obo*kh:Lm. 31 no.8:2739-2743 Ag 161. (MIRA 14:8)
1. Institut organiohesko~ khimii AN Ukrainskoy ~M-
(Oxami4e

_E~L KIS , P,,S. ; RRETYAHKO, M. Z.
Synthesis of substituted -erivatives of 1.,/+-dipheny:Ltli-,:osemiearbazide*
Zhur, ob. Xaim- 31 no. n:3726-3728 11 161. (MJRA 14: n)
1. Inotitut organicheskoy khiraii AN Ukrainsko; r SSR.
(Semicarbazide)

.65, ~-_: :- i
Mir,
AC_rXSSFa,, HK- ATS0138044

;AMIHOR., Gvvdetskiy, A. A.; Dubemko, R. G.; Pell kis,_,~,S.; Ryaboya. E. Z.
ives of d..ai7l~tblocaT~'Dol)ydrazidds in the prop~:ylaxis of acute rz,. di -
~_T_31~'~r, Der. tvat
,
.74
j
1L
L
L
L
'1u6hayykh__ porA*anly
tik~t a

e, L Pm r-j-duition inj a sbbrmik
veption, ran
Oathogenes
~Istatiwi. Moscow, I zd-vo Meditsina, 1-964, 179-192
"TOPIC; TAGS: diaWlthiocarbobydrazide, radiation protection, radiation sickness
of

r
-A T: The action o1 new radiation protection preparziti,,-ns of the gm_,u:
_T
--leri-va-LiVes
YaFa

34 radiation protec
thi6cai6ithydrazide werpe synthesized and etudied as
tion . agent:;. It was shown that t~iese derivatives are able to form internal co-m-
;Plexes catlons of heavy netals, that they possess mducing properties, an d ,
~[epen.Lng Dn the pH of ':he -nedi,_m, react in the thion or tY.-Jol fcom . The greatest
!
oprote~:tive activity in -the irradiation of animals with lettal dozes of x-rays is
iexhibLted ~y the 6sriva-:ives of '.,5-diphenylthiocarh~ohydra2i-de and `,3-diphenyi-
.-thicoirbamide witl SubsLitUtions which give them solubilitt~ in water: disodium
L/2

'ACCESSI ATS608044
;salt I.; S-di -(4-sulf onaphit~nyl)-th:ioc,--rbo7nvdra7ld~-- (praparaticD No. 1-2), disod-41ALM
vpreparattic nNo. 19), 1,5-04-
arddor~-ilfa-iyl,ofleryl)-thi:-)carbohydrazie,e ioreparation ,No. 9). and d i S o"' un ~i a
CtAV6 Posse D~ActA toxia- broperties- Orig
Z. rat is
has: :5, ligm-is, 3 .-tables, 8 forn., ulas
ASSOCIkTION-.: none
SUP cow-: LS,00
ISUBMITMD: ISAV7-611 ENCL: -06

DUBENKOY R,G,; PELIKIS, P,S,
Study in the a-ries of ary1hydrazones, substitution derivatives
of glycxylic acid (111), Zhur, org. khim. I ncs.7:.1255-1260 il
165. (MIRA :L8.-11)
1. Institut organicheskoy khinii AN UkrSSR.

BORISMCHY A.N.; PRLIKJS~ P.S.
Cycilzation of 20,4-p5nt-antrione
ores khim, I no,7:3297-2299 J-2 '65.
1. InstitiA organj.chcL;kcy khimii All

pD~IKO LS~!-
I I
L-. I _.:,,
5yntheg;js and study c7- hsymet' 4c dis-y! "- -1 S % v *-
halo and carboxy subs I., itueffits. Zhur. org,, khim. 1
738 RAJ, 6~.. MIJ.)
1. inat-Itut orgir-ri~hc.-,;,?~oy khImJA AN Ukr~iSh,,

LOZINSMI 11.0.; PEMKIS, P,S.,
Condensation ani cyclization reactions of Arylazo chl-nroacetle
ac.-Is. Part 2, lsotbio~-yanates and selenocyanate!3 of arylazo
chloroacetic acids and their reactions vitb aromatlc P-mines,
Zhtw. org. khlm. 2 nG~8,~1415-1422 Ag '65c Wlil~. 18;11)
1, Institut organichesk-y ichlatil AN Ukr,95F,
I

NESYNOVY Ye.p.; BEZTROVANNAYA, M.M.; PELIKISp P,S,
y1 esterfi of arylazophenoxymalonic acidp Zhur arg. kbim.
Diettr
1 no.lljl.963-1965 N 165. iMIRA 18t12)
1. Institut o~ganlcbeskqy khimij AN UkrSSR. SuWtted
November 91 1964o

IFACC Qt -AP6023580 SOURCE CODE: UR/0409/61$/000/003/0368/0371-------
AUTVIORs Bovioevichg Ao No; Shulezhkom S. A.; Pel"kis Po So
ORGt institute o 'f Organic Chemistry, Academy of Sciences UkrSSR.,
(Inlititut organicheakoy khimii AkademiL nauk Ukr$13R)
TITLE: Arylamides of substituted thioacetic acid. 111. CyelLzation
of dirylamides of acetylthioacetic acid
SOURCE: Khimiya geterotaiklicheakikh soyedinenLy. no.* 3, 1966,
3681.371
TOPIC TA.GSi acetylmethylenearylphenylthiazolineI acetylmethylone-
arylthia.zoliAone.., ,.V,o4A
ApSTRACT's
:Pr,eviousl unreported 2-(acetylmethylene)-3-aryl-4-phenylthiazolines
(see Table 1).werle obtained by boiling an equimolar mixture of
arylamides of acety~thioaceftd acid with w-:bromoacetopherone in ethanol
Pfactions,
Ind separation on.a chromatographic coluum.packed with A1203-
Card 1/3 UDC t 547.292+542o952.52

ACC:NRs
lambl&- 1; '2-(
- see 4wihylene), -i3 14-pfiinylthiazol"in~~
ty -ary
p~
C48COCIO-6 C-yy
S"C"
MP.,*C la Found ,%jja ca-1 Yield
-C R ir e
,~k
on
H 215-216 COiasNOS' 11.03; 11.04 10.95 52
P-CH3 ma-m. C,,H,,NOS 10.26:10.23 10,43 50
ill P-OCH3 145-146 CIpHAW 9,80; 9,77 9190 62
IV o-OCH3 DleZE IN C,lHj7NOsS 9,98; 9,98 9.90 48
V -p-Or,2H, 132-133 C4APNOA W34; 9.28 9.48 63
11ouudi C 73,79, ran; P. 6,01; 5.03; N 4,99; 6,09%;'M 292,4, Cal"tBd: C 73,65;-
N 4,77%; At 293A
'Rf arylainides of acetylthloacetic acid with monochloroacetic acid in
.the presence.of anhydrous sodium acetate in glacialacetic acid yielded:
-ithe.prevLously unreported 2-(acetylmethylene)-3-aryl-4-tbiazolidones:-
.. . . . . ................... .......

ACC NR# AP601_3_58~0
Table 2. 2-(acetylita thylene)-3-aryl-4-thiatolidones

ot:ocu.e

Compoumn T
V
tmula Found S % ed. Y~Ybld
TIO. .
P.N

v I 204-206 Cj,H INOjS 13.46; 13.45 13.75 34
vil p.CHs 1200L:-202 Ci3Hi3NO2S* IZ86; 12,87 13.01 4:1
vill POCH, 2M-202 C13Hl,NO3S 11,95, 12.02 12.19 4.1.
i
IX o-oc"s 145-146 CIIH,3NO3S 12, 18; 12,26 IZ19 41)
X, P-OCA 163-164 j:jjHjjNO3S. 11,64; 11.63 11.56 5o

V-
01,
Ca4QwkAi'd.C 0
03%,
FOqnd: C 63
Af 266
9
N 6
6
13;
36
63
H 6
32
31; 5
.
.
.
,
;
-H
429; N 5,661~. M
24l,32.___ ,
.
,
,
.
_t._---- .
.
.
,
7
_
pr ig atlt -::2 CBE
[W#A,50;
No,. 101
SUB :,d0D4l,'-_ 07./ SUM DATES 04j ,
i
au65/ ORIC UPS 002/' OTH REF t 006

I-Card .3 3

LcarLi 5 UDCt .547,789#5o542.952,.52

ACC NRT-AP6 0 2 3 5 7 9
Table 1.

H
AC-N-C H4R
6 A
~.C
Ilk (CN)COOC,
.
' M
X T alcula
d '
Yield
.
.0C 9*p formula Found S, % S.
~ ,
%
I H >240 CnHjs0xN2S 9,23, 9,28 9,19 94
2 P-CHS 2M C2lHtaOzN2S 8,70. 8.65 8.86 0
-3 P-CH20 168 CsjHjs02N2S -8,79; 8,87 8,41 81.
4 A-0 210 CnHjs0sNjSC1 8.42; 8.44 8,36 85
5 -P-NHsS0s >240 C4oHjj04NjSg 14.86; 14.90 14,98 68
6 P-CAGO-C 218 CnHnOAS 7,63; 7.61 7.62 91
.7 p-N0j IGO Cv9Hjj04N3S 82
rivau~
amide malanic eaters, the- resultant 2-carbethoxycyanomethylene de
itives of thiazole resist saponification with aqueous or alcoholic KOJI
,or with-60% sulfuric acid. Reaction of diethyl ea ters of a rylamides-
,of thiaEarboxymalonic acid with w-bromoacetaphenone yielded 2-carbothoxy-
-methyl ene- 3-aryl-4-phenylthiazoles. When the reac tion time on a steam.
Cmd 2/5-

ACC NRv AP6023579

Table 2.
H5c6C---N-C H R
6 4

N IC-CI'COOC2f'5
HC
S

~ alcubted Y:Leld

R T..M
Cp p
Formal&

ound S. S
%
203 CjjHjj0jNS 9,77; 0,62 9.90 94
7-C3HI0 144 .
C31HIANS
8,54; 8.53 8.72 9G
P-NO, 152-IM Ci'HjsO4N3S 8,59; 8.54 8.69 71
p-NH,SO' Does not CjoHjs04N3Sj 16,29. 16,32 1
5,92 90
-melt
Aath Is shortened, or the reaction mixture is left to stand overnight
:at room temperature,.,Q--;(Iicarbethoxymethylene-3-aryl-4-pheny.ltliiaz6lea
iare formed. On heating for 3-4 hours, 16so of's carbethorr. group re-.i
sults in ~.Drmation of 2--carbethoxymetbylene-3-aryl-4-phenylthiazoles.
Card 3 5

ACC Nitt AP6023579
0
:Heating of' diarylamides of dithiomalonic acid with W-brommacet'phenone
myields exclusively monobromides of 3,31-diaryl-4,41-dipheayl-2-methine--.1
I ditWazoles.
Table 3.
Hbc6C-N-C611 4R
tic., e~-C(Cooc H
2 5)2
S.
R T.,.rap. Formula Calculated Yield,
Foufid S. S.
z
I H Ifa CuHtANS 7,90. 7.97 8.10
-2 p-CHs HO CvHtANS 7.95; 8.02 7.82 66
3 P-CIHIO 118 qiH2sOsNS 7,52; 7.37 7.28 85
4
p-Br 168--164 C"H,s04NSBr 6.44; 6.36 6.75 7D
5 p.N(h- CbHj6OsN.,S 7,39; 7.47 7.27 67
Card 4/5

ACC Nib AP6023579
Table' 4.
RIIJ.C4 611 4R
.11 C -C-N
N-C-C,1116 Or
5 6
cil - Cycil
R T. irp., c
I Fomula Found' S. %
I CalcuLibo4j
% YIV4,

-H 04-
D21t
;
C,,H:,NxSjBr
10.93; 10,70
25
11
1
85

p4
Klo ~ c H N3SIB

3 3101 r
3 9,96; 10.02 .
1 17
0
:

3
3 a-CAO C3lH3.OSN2S,Br 9,94; 9,87 9,77 78
4 P-ClHzo uH3,0,N,S,Br 9.61;. 9.4 6 9,71 86
Orige art, has:. 4 tables. (W. A. 50; CBE No.*101
SUB ODDE: 07/, SUBH DATE: .31D.ec6411 ORIG REP: 004/ OTH REP: 601

CoM 515

ACC NRs AP6025392 SOURCE CODE: UR/0366/661002100711213/1220
AUTHORs Nasynovs Yes P,,; Beaprozvannaya, M. M,; PaIlkial P, S.
ORG: Inotitute of~ Organic Chemistry, Academy of Scioncea)UkrSSR
(Institul: organicheakoy.khimii Akademii nauk UkrSSR)
TITLEt Prepitration of ary1hydrazones of diethyl meooicalate
SOURCUt Zhurnal ovganii3hoskoy khimii, v, 2, not 7, 1966g 1.113-1220
TOPIC TAGSJ hydrazone, mesoxalate escer, condensa tion reaction,'
isomerisTA 9 69jC60VILIC- t9CID.t 11tfDR#3 ZWE CornPoc.?&~O I 1;5,~vfnEp-
ABSTRACTv
This work is a continuation of the study of physiologically active
taryazocarboxylic acids. Reaction of mal6nic ester with aryldiazonium
.salts-yiel.ds a:rylhydrazones of diethyl mesoxalate. A reaction by-~product
.consists cof diethyl diar'ylazomalonates. The arylhydrazones.were separatedi
C11 coo (c.,ij,O0C)2C 'NNIIAr
(CJII.OOC)j62+ArN-=N+GI
(CjH5OOC)2C(N=NAr)j
Card 1/2. UDC: 547.556.9

ACC NRt AP6025392
-into-isohiers' by elution, chromatography on alumina;. 11V 'and IR speZtra of the
isomers were recorded. It is suggested that the existence of isomers is
,determined not only by --is-trans isomerism about the C-N bond.~.butal,00
.-by hydrazone-g~ZO tautomerism. i'
Or ig. ar t. has: 2 tableA.
LW.A- 50; CBE No. 101
SUB CODE:'-'07/- -SUBM DATE: 26Apr65/ ORIG REP: .003/ OTH REP:, 004

UIV,
WI A WRO i7 16 Mmogmph
k~kv. Aleksey AfmaslyevichL Pellkis, Petr SolomonovIft.Ryabova Era
F6VTY3 DLbenlco, Roza Gripor Ye
di"ation properties of aryl atddes and aryl hYdrazides of thiocarbcnic acids
-7
(I%-Um-Dluchevyye s%n)ystva arilamLdov i arilgLdrazidov tickarbonovykh kislot)
rdev,, Izd-vo "Naukova. dwrkai~ 1964. 110 p, illus.., biblio. 1600 copies printed.
OLt head of title: Akaderdyi nauk UkrWnskoy SSR. Institut. ftziolqgLi. AMt
A. B~~11~tsa. -m iti&-Co-r-
agdql~skoy. khifilf
7MC TAGS: antiradiation drug, radiation protection, amide, hydrazide, pharma-
00,10gr
AND COVERAGE: Mis mnograph is the result of searxi-es for and tests of
now antiradiation std).stances. A series of substituted aryl amides and aryl
hydrazicies of thioca:bovylic acids were synthesized and investigated. Mie
q, -0,es axe reducing aWnts., capable of forming various inner
o, pounds of this se.
c
donplexes, and also, depending on pH, can exist In the t1don or thiol form.
VarLous symotrical and unsymotrical derivatives of thicicarbanil-ide, 1, 5-di-
phenylthiocarbobydragdfde, were also synthesized and biologLeally investigated.
rhirty-six newly synlaesized. substances were subjected to biologLcal testing of
their prophylactic properties. 11bepther with investigations of the effect of
the synthesized prepiwations on the clinical course and result of radiation
injurieB,. thi,,toxtcological md phannaeologLeal properties of the most effective
Cowd 1/2

ACC HRI A$001716
oWstanims were studied, and also the distribution of the conpounds, means and
mbe of their elimination fYvm the o~rganism. 7he rwnoMph is intended for
rai*Robiologists-, synthetic chemists, biologists, and doctors.
TABIE CIP OVIEWS
Introduction 3
Ch. L Antiradiation properties of nitmepn- and sulfur-ombaining orgmic
001,rpounds - 5
Ch. IL D%rIvatives of thiocarbanilide End their prophylactic antiradiation
action - 22
Ch. III. Substituted 1., 5-dipherWlthiocarbohydrazides and their antiradiation
effect - 53
Ch. Dr. Elimination of oesium-134. from the organism under the influence of 1,
5-diphelkylthiocarbazone and 1, 5-diphenythiocartchydrazickt derivatives 94
Conclusion - 101
Biblicograpky, 106 [131
SUB OCCE: 07/ SUBM DATE: 13Mar64/ SOV IEF: 064/ 0711 HT: 134/
car4,

4`17L-6.6
ACC NRt
AR603-4530
SOURCE CODEt UR/b091/65/0O0/0lq/,qW4AG44
AUTHCW: Gorodetski~r. A. A.; Dubanko, R. G.; Pellkis P. S,; Ryabova., E6 Z
:TITIJ;*.- Darivatives of dj~L of,3
~Ithioqarbohydrazidolin the prophylactic treaiment
aclitti radLation sickness
SOIMI',F.! ef. AbS. 19M156
no
REF 3OURaF,:- Sb. Patogonez, eksperim. profilaktika I terapgr.0 vykh porazbeni,,r.
M,-,' 14editsina.10,". Y/9-192
TOPIC TAGS: radiation sicknessp x-ray irradiation, antiradiation. drugp hydrazine
POMpound, toxicity,
ABS73AM. A series of substituted 1,5-diphorqlthiocarbohydrazides of general struc-
~turei (ArEM02CS, (Ia-s, whore a, Ar = 2j/+-(CH b. Ar = 2,5-(rH3)2C6H3; o,
3)2C6H3;
Ar 3o4--(CH3)2C6H3; dt Ar = /+-i11043H7G6114; as Ar = 3-0113CC61fll f, Ar = 4-C2H500"
cc Ar = 2-02H5OC6H4; h. Ar = 2-CH3SC04; i, Ar = 4-H2NSO2G6H4; J, Ar
4- 1'(2--o,-hYi-l,,3.,4-thJadiazolyl-5)-aminosulfonyl I -phenyl; k, Ar 4- [(/+,6-dimethyl,-~
pyrlidc -2-aminosulfon;rlj
' dy,. L -phenyl; Ar = 4- VaO SC04; m, Ar 2-CIC644; up
3
Ar -G' 6H4A o'
3 1C Ar 2-1004; P, Ar 4-IC04; q, Ar 2:,4-(CI)2003; r, Ar
Cc d-.

DUBEHO, R.G.; TANGHUK, Yu.V;.; KISiLENKO, A.A.; PELIKILS, P.S.
Synthesis and study of trimetl7len-- trlsallfone derzivatJves.
Part' 3: Infrared spectra of arylazo and arylhydrazono derivatives
of 2,4,6-trimethylem 1,3,5-trisulfone. Zhurr. org. khim. 1
no.9:1692-1696 S 165. (MIRA lgil2)
1. Institut organicheskoy khimii AN Ukrainskoy SSR, Subaitted
March 17, 1964.

PUPYW) L.S.; DYCHUT0, A.I.; PE41 K'
Synthesis of i47=0xical derivatives of 54-ydroxy-2,3 d-J'ar-11
totrazollum bAalne. 111fr. Him. zlmr- 31 no. Vt1306-13109 165
(MIRA 19:1)
1. Institut organicheskoy khimii AY, UkrSSR. S%lmitted October 1,
1964.

DUBENKOJI R.G.; TAIC141%,
I Synthenis and study of trimethylew trisulforic derivativeE.
Part 4: Arylazo derivatives of 2.,4,6-trimethylene 1,3,5-
trisulfone and products of their reduction. Zhur. org. khIm.
1 no.9:169&,1699 S 165. (MIRA 18:12)
1. Institut organicheskoy khImIi AN Ukrainskoy SSR. Submitted
April 13, 1964-

DUBMKOP R.G.; USEM, Yu.N.: PELIXTS, P*S.
kryl h2dr&zones of ethyl eater of arylsulfanylglyoxylic acid.
Pb~rt 3sMethyl ester of arylazo- and arylaulfaiy1nialonic acid
end their derivatives. Zhur. org. khim,, 1 no. IW181-21186
D 165 (Min l9-.1)
1. Institut organicheskoy khimii AN UkrSSR. Stbmitted November 249
1,964.

LOZINSKIY,
Synthesis of 104-diaryl-194,.dihydro 1,2,40-tatrazines. Zhur.
org. khim. 1 no',4:798-799 Ap 165. (MMA 18;11)
1. Inatitut organicheskoy khimii AN UkrSSR.

LOZINSK-1r, M.O.;_j, P.S.
Reactions of condensation and cyclizatilon of axylazacl-Axwoace tic
acids. Part 5s Chlorides, arylamidea, and aeyl,17drazidos of
.arylazoahl.oroadetic acids* Zhur. org. khim. 1 no.11:1970-1981
N 165. (MIRA 18:12)
1,,Inatitut organicheakoy khimii AN UkrSSR. Suibmitted December l1,,
1964.
M~Aq a-20 LI-A

!;ynthfiai!3 "d st-,Iiy pr
U-
6t Roacrion tf
der, ...11ters vith U-Ugat-lift-tel :t'o='pctl--av.
N 165,
i i'v- u Ii D rit, a nn h ea ky ki I A t I i k. S R
itVp 1964.

R.G.; USITKO, Yu.N.; PSLIKIS P.S.
Ary1hydrazones of -the ettq.L esTer.-,of-.a--yisal-~mylglyoxi-lic acid.
Part 1. Zilur.org.khim. I no,3:570-572 Mr 965,,
(MIRA :L8:4)
1. Institiat organicheskoy khimii AN UkrSSR.

- i I - - .- . I -I- - - -- I I-. I - -- , - - . -- -:- ~-- - I -- - - , . -
.: - ; , - I

are cbtained alonc," pa -phenyl uubgu 4ute-d
4
jtsgli b'' en
AZ6 ~6644- M~-' rod
Btructi-are- of: the :reatidcn ucts has be
7; -confJimad-, by --spectrosmpiz investigationo 1, 4-di (o-nitrophonyl)
1.2~4.5-tstrazivo' hav jroxim= in the ldtraviol-et absorption opectma nt 228,
a nd 4-16 m (in aicoho!)3 ar4 this agreas with daia from the Idtfrat,.ire. The
JR 5pectrum shows intensive absorption bands at 1590-1610 cm--1 (a3suciated with
C -1, 1;L-diar7I-lL-djhy-dro 'i,2,1s,.6-tatrazines are ci)lored cry'5talline SIAb-
vtances, soluble in dioxane, aaztcne, benzime, iv-,iaccial ace-tic acid.
I.Icorio.L, uid ether., but n~ra ni-at, BulubID in or N-ater.

-,)YNOV, IE ,
lias
tip
mthese2 in
b~ _rr ~de a-,
AN URSR no.&IORSC-1082 162.
1. Institut organicheskoy kiLimij AN UkrSSR.

LOZIRSKIY, M.O.; SANOVA, S.N.; ~ ~s P.S.
1,,5--Diar7l-3-(arylsulfonyl) formazans. Zhur.org.khim. 1 no.2:314-
318 F 165* (MIRA, 18:4)
1. Institut organicheakoy khimii AN UkrSSR.

DUBENKOI, R.G.; PELIKIS, P.S..
Series of aryl hydrazones of substituted phenylglyoxylic acid
chloride. Part'3: Synthesis of aryl hydrazones o.It' p-nitrophe-
nylglyoxylic acid chloride and nucleophilic exchamp reactions.
Zhur. ob. kh:Lm. 34 no.10:3481-3484 0 164.
(MIRA 17:11)
1. Institut organicheskoy khimil AN 11krSSR.

NESYNOV, Ye.P.; PELIKIS, P.S.
Reduction of 1.5-diaryl tatrazolium betaines. Zhur. obs khi . A
no,8t267,1-2676 Ag '64. (?-IJPk 17:9)
Institut organicheskoy khimii AN UkrSSR.

%IJKM!, -S.; SANOVA,. S.N.
IZZINSKIY, M.O.;_P .-T
Pr aration of arylazochlo-r-azet-ice ascids and
1.3.4 -I..3,4-oxadiazolin-5-one. Ukr. khim. zhur. 30
42!
no.lt68-72 164, OURA 17:6)
1. Institut organichaskoy khimii AN UkYSSR.

DUM;NKO, R.G.; TAINCOK, Yu.V.; PEL?KIS, P.S.
Synthesis and investigation ot" triwithylenetri-su~low
derivatives. Part 2-.Arylhydrazono-and aryl azo darivatives
of trimethylenetrisulfone. Zhur. ob. khim. 3.4 no. 52
1636-1638 Kf 164. (MIRA 17:7)
1. Institut organicheskoy khimii AN UkrSSR.

GORODETSKIY~ Aleksey Afanaslyevich, prof.; PELIKIS, Petr Solomonovich,
doktor kbim. nauk., prof.; RYABOVA, tri~'Zinbv yevbbL;
Roza Grigorfyowa; YAJIKOVSYAYAt Z.B., red.
[Radiation-protective properties of arylamides and
ary1hydrazides of thiocarboxylic acids] Protivoluchevye
svoist-va arilamidov i arilgidrazidov tiokarbonovykh kislot.
Kiev, "llaukova dumka)" 196/+. .110 p. WRA 17:8)
1. Chlen-korro8pondent MI Ukr.SSR (for Gorodotskiy).

DUMIKO,
Aryl hydrazones of substituted phanylglyoxi:Lic acid chloride. Part 2:
Roaction of aryl hydrazones of substituted phanylglyoxilic chloride
with nucleopnilic agents. Zhur.ob.khlm. 34 no.2:679-682 k' 161,.
(MIRA 17:3)
1. Institut organicheskoy khimii AN UkrSSR.