CONSERVED-TISSUE THERAPY ACCORDING TO FILATOV FOR TREATING NONHEALING WOUNDS AND ULCERS

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP80-00809A000600400459-8
• Release Decision: RIPPUB
• Original Classification: C
• Document Page Count: 4
• Document Creation Date: December 22, 2016
• Document Release Date: August 25, 2011
• Sequence Number: 459
• Publication Date: July 27, 1951
• Content Type: REPORT

Sanitized Copy Approved for Release 2011/08/25: CIA-RDP80-00809A000600400459-8
CENTRAL INTELLIGENCE AGENCY REPORT
INFORMATION FROM
FOREIGN DOCUMENTS OR RADIO BROADCASTS CD NO.
CLASSIFICATION CONFIDENTIAL
COUNTRY USSR
SUBJECT Scientific - Medical, tissue therapy
HOW
PUBLISHED Monthly periodical
WHERE
PUBLISHED Moscow
DATE
PUBLISHED Feb 1946
LANGUAGE
This DOCUNSNT CONTAINS INFORMATION AFIICTINN TIPS NATIONAL DEFENSE
or THE UNITED STATES WITHIN lift NOANINS Or SSFIONASI ACT NO
N. S. C.. S I AND II. AN AMENDED. ITS TIANSMISSION OR THE NOTLLATION
Or ITS CONTESTS II ANT ^ANEIt TO AN UNAUTNONIISO I.NION IS FRO?
HISIT%. AT LAN. REPRODUCTION or TN13 FORM IS FNOHISITIO.
Khirurgiya, No 2, 1946, pp 12-14.
DATE OF
INFORMATION 1946
DATE DIST. 47 Jul 1951
SUPPLEMENT TO
REPORT NO.
CONSERVED-TISSUE THERAPY ACCORDING TO FIIATOV
Pwz'REATING NONHEALING WOUNDS AND ULCERS
Si:.Dj.Goligorskiy
Clinic, Faculty of Surgery
Kishinev Med. Inst
Filatov's method of therapy with conserved tissue has found wide use. A
number of reports by scientists (Kal'f, Kashuk, Gershkovich, Skorodinskaya,
Dune, and others) have also shown the effectiveness of this method in diseases
other than those of the eyes.
The stimulating action of conserved tissues led to the idea of the ex-
pediency of using this treatment for wounds and ulcers which would not heal for
a long time. Among our cases, the duration of illness of some patients was more
than 6 months, and in one case reached 16 months. For that reason, we are pub-
lishing the results obtained by using conserved tissue according to Filatov's
method.
Conserved-tissue therapy was used and checked by us on 30 cr es with wounds
and ulcers which failed to heal for a long time. Until use of conserved-tissue
therapy, all these wounded had. been subjecte&r _fully to other forms of
treatment, such as paraffin therapy, irradiation with ultraviolet rays, adhesive
plaster bandages according to Baynton, excision of the wound or ulcer within
confines of the healthy tissue with a suture completely closing the wound (in
the cases of five wounded), etc.
The duration of illness in these cases was as follows: 1-2 months, 7 cases;
2-3 months, 6 cases; 3-4 months, 8 cases; 4-6 months, 4 cases; 6-16 months, 5
cases.
In the majority of the 'cases the nonhe@;l.ii]g-Ulcers` sad:Wuads'Yere on.the lower
extremetiesi on the buttocks, 2 cases; on the hip, 12; on the knee, 8; on the
foot, 1; on the shoulder, back, and abdominal wall, 3 cases.
-1-
CDNFID T CONFIDENTIAL
DISTRIBUTION
Sanitized Copy Approved for Release 2011/08/25: CIA-RDP80-00809A000600400459-8
 Sanitized Copy Approved for Release 2011/08/25: CIA-RDP8O-00809AO00600400459-8
CONFIDED
CONFIDENTIAL
Tn all cases, we used skin as tissue material. The method is extremely
simple. An elliptical flap, 4-7 cm long and 1.5-2 cm wide, is cut from the
abdominal wall. The skin flap is taken without the subcutane3us-cell tissue.
For conservation, it is submerged in a sterile, hermetically closed jar and
put on ice. The flaps are conserved in this manner for 8-10 days. upon ex-
piration of that period, an incision is made near the nonhealing wound or
ulcer. The length of the incision corresponds to the length of the conserved
skin flap. The edges of the incision are separated and the skin flap is placed
into the resulting bed. It is closed with two sutures, fixing the flap in
position.
In 88% of the cases, we obtained initial tension, while in 12 percent, the
flap implanted. subcutaneously became necrotic and came off in the form of a
scab. Temperature reaction of the patients seemed to be absent.
A change in the clinical course of the illness was observed during the
first days after the implantation of the skin flap. The bottom of the ulcers
became covered. with juicy, red granulations, the edges became depressed, and
epithelization began to take place at first from the periphery, and then by
bridging. In the majority of cases, the healing process until complete re-
covery was quick. In three cases (10%), a repeated implantation of conserved
tissue had to be performed. In five cases (20%), the treatment remained with-
out effect.
in 25 cases of full recovery from nonhealing ulcers and wounds, the fol-
lowing periods elapsed between the moment of implantation of conserved skin flap
and complete recovery; in 3 cases, 7-10 days; in 10 cases, 10-20 days; in 6
cases, 20-30 days; in 4 cases, 30-40 days.
The scars were always smooth and did not interfere with movement. It is
interesting to note that in cases in which a repeated application of the method
was carried out to stimulate the healing process when it stopped, this process
set in again with particular intensity after the repeated application. We give
a few brief case histories for illustration.
Pvt P. (case No 1824), nonhealing ulcer on left hip.
On 21 January 1943, Pvt P suffered a splinter wound in the soft tissue
of the lefi hip. in the first stage of the evacuation, an excision of the wound
was performed. From the time that he was wounded, the patient was treated with-
out effect in several hospitals for ulcers which had formed at the site of the
wound, and two surgical excisions were carried out for that reason. On 27
November, 10 months after the time he was wounded., a large scar was found on the
outer surface of the middle third of the left hip. Its dimensions were 14 x 7
cm, and it had an ulcer 5 x 3 cm in dimension, with callous edges of 0.5-cm
depth in the center and an uneven bottom covered with sluggish granulations.
On 30 November, a skin flap 4 x 1.5 cm in size was cut from the forward ab-
dominal wall and immersed for conservation. On 7 December, the skin flap,
had been conserved for 7 days, was implanted on the forward surface of the left
hip. on 10 December, the edge of the ulcer became flatter, the ground was
covered with red granulations, and the size was reduced to 4.5 x 2 cm. On 13
December, the ulcer continued to decrease; its dimensions were 4 x 1.3 cm and
the granulations were active. On 15 December, the wound epithelized intensively
from the edges and its dimensions were reduced to 3 x 1 cm. On 19 December, the
condition of the ulcer continued to improve. Epithelization proceeded from the
edges; the dimensions were 2 x 1 cm. On 24 December, the ulcer was completely
healed.
In this manner, an ulcer which had failed to respond to effect of and im-
planted treatment for 10 months, was healed within 17 days by the
planted conserved skin.
Sgt p. (case No 2787), ulcer in the region of the Achilles tendon.
COMFIDENTJM.
Sanitized Copy Approved for Release 2011/08/25: CIA-RDP80-0O809AO0O600400459-8
 Sanitized Copy Approved for Release 2011/08/25: CIA-RDP80-00809A000600400459-8
CONFIDENT'.::
CONFIDENTIAL
On 26 October 1943, Sgt P suffered open bullet wound of the soft tissue
the left knee and a grazing bullet wound in the region of the right Achilles
tendon, in the firc.t stage of evacuation, surgical treatment of the wounds was
performed and a plaster cast applied.
On 29 November, the patient entered our hospital with strengthened scars
in the region of the left knee and with an ulcer in the region of the right
Achilles tendon. The ulcer measured 7 x 4 cm, with broken edges and gray granu-
lations. The pain made movement of the right ankle impossible.
On :; December, a skin flap was taken from the forward abdominal wall
and conserved. Its dimensions were 4 x 1.5 cm.
On 1!+ December, the skin flap which had been conserved for 11 days was
implanted in the subcutaneous tissue of the inner surface of the middle third
of the right leg.
on 16 December, the ulcer revived; the granulations became red, the
edges became smooth and began to epithelize.
On 18 December, the size of the ulcer had decreased considerably; it
was 5.5 x 2.5 cm.._ Movement of the right ankle had become less painful.
On 21 December, the condition of the ulcer continued to improve. Epi-
theliza.tion proceeded from the edges and in proturberances.
on 25 December, the dimensions of the ulcer had decreased.; the granula-
tion was juicy and red.,. On 29 December, the ulcer had decreased in dimension
to 3.5 x. 1.7 cm. on 2 January 1944, the granulation was fresh and red, epitheli-
ration was proceeding from the edges, and the dimension of the ulcer was 2 x 1
cm. Movement of the ankle was free and painless.
on 9 January, the ulcer was completely healed.
Pvt D. (case No 2294), ulcers on the stump of the right foot after third-
degree frostbite.
On 25 December 1911, the patient suffered third-degree frostbite of both
feet, and both legs were amputated at the level of the metatarsus.
On 20 November 1942 (11 months after suffering the frostbite), the
patient entered our hospital with ulcers of both stumps, each.of 8 x 3 cm di-
mension.
In the hospital, reamputation of the right stump was performed. An X-
ray of the left stump, taken 15 April 1943, showed no osteomyelitic process. On
5 May (16 months after the frostbite), the ulcer of the left foot stump had the
dimension of 6 x 1.5 cm. On 5 May, a skin flap with dimensions 7 x 3 cm was
taken from the forward abdominal wall and conserved. On 14 May, the skin flap,
which had been conserved for 9 days, was implanted on the inner surface of the
middle third of the left leg.
on 18 May (4 days after the implantation of the skin flap), considerable
change occurred in the condition of the 16-month-old ulcer; the granulations be-
came juicy, epithelization from the edges began to proceed intensively, and the
dimensions of the ulcer were down to 4.2 x 1 cm. On 21 May, the ulcer had a
size of 3 x 0.8 cm. The granulations were red, the edges smooth. On 25 May,
the dimensions of the ulcer were 2 x 0.8 cm, epithelization continued to pro-
ceed from the edges, and the granulations were juicy. On 28 May, the size of
the ulcer was 1 x 0.8 cm. on 2 June, it had healed completely.
CONFIDENTIAL
MMLSanitized Copy Approved for Release 2011/08/25: CIA-RDP80-00809A000600400459-8
 Sanitized Copy Approved for Release 2011/08/25: CIA-RDP80-00809A000600400459-8
CONFIDED:.;
Conserved-tissue therapy according to Academician Filatov's method is most
effective in treating nonhealing wounds and ulcers. The time of treatment is
iuuch shorter compared to other methods of treatment. In addition, Filatov's
method was used on cases which did not respond to other methods of treatment
for a long time. Conserved-tissue therapy should be widely used in cases of non-
hea.ling wounds and ulcers.
4 -
CONFIDENTIAL _
CONFIDENTIAL
Sanitized Copy Approved for Release 2011/08/25: CIA-RDP80-00809A000600400459-8 ~~~?