F,~rments- Keys to the Mysteries of Life SOV/219-59-3-16/23
A, Ye Danilevskiy in the last century This discovery was of
principal importance and formed the baste of a number of in-
vestigations in the field of albumin syntbesis. A special fea-
ture of ferments is their asnaitivity to temperature, especially
to high temperatures (70-80 ), Each Terment has a no-called
optimum temperature which favors its activity. In addition,
they are sensitive to acids and alkalis. Each ferment has an ef-
fect on a definite substrate or on a special kind of chemical
bonds in the molecule. This exclusive selectivity of fermenta
is not only important to biologists and physicians, but it is
also extraordinarily important in commercial chemistry to make
proper use of this selectivity. In order to obtain catalysts
without geoundary effects, the basis of the selectivity of
ferments must be clearly understood. Therefore it was necessary
to study the structure of ferment albumins. They were separated
in pure state from various organs and tissues, which proved to
be very difficult. Recently it was possible to obtain a number
of ferments in absolutely pure state and to investigate their
structure. It was shown that the peculiar components of which
the albumin is maAe up are so-called amino acids. More than
Card 2/4 twenty ~Ifferent amino acids are already known of which the
Ferments Keys to the Mysteries of Life SOV/29-59-3-16/23
albumir is composed. One of the moot important achievements
during the last years is the statement that the specifity of
ferment albumins depends on the order of amino acids which form
the peptide chain. Further, it was found that the specifity of
a ferment depends on an active center of a smaller section of
the peptide chain with a characteristic order of amino acids.
Yet there is no rule without exception of which some cases are
indicative where one and the same ferment exercises influence
upon various chemical substances. It was found that ferment
activity is increased or lowered by the action of some very
simple chemical compounds. The activating or paralyzing aub-
stances can be very specific. These phenomena play an important
part in the living organism since there is a number of ferments
in the body which become active only under certain conditions.
This was demonstrated for the first time by I. P. Favlov and
hie
students with the example of digestive ferments. Since
virtually
all animal and plant tissues contain ferments, all organic
albumins may be assumed to be ferments. This is confirmed by a
discovery of the Soviet scientists V. A. EngelOgardt and
M. N. Lyubimova, who found that the muscular myosin is a
ferment.
Card 3/4 The individual ferments differ insofar as they are
simple and
Ferments Keys to the Mysteries of Life SOV/29-59-3-16/23
complex ferments. Modern science makes use of ferments in
various fields. There are 6 figures.
Card 4/4
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