SCIENTIFIC ABSTRACT V.F. CHERKASOVA - P.M. CHERKASSKAYA

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R000308420012-1
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: June 12, 2000
• Sequence Number: 12
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

LOZOVOYP A.V.,- MUSELEVICH, D.L.; RAVIKOVICH, T.M.; SENYAVIN, S.A.; TITOVA, T.A.;
CHERYJSOVA V.F.; Prinimali uchastiye: DEMBOVSKAYA, Ye.A.;
LIYOVA, L.N.;' MARKINA, T.I.
Hydrogenation catalysts on an sliminosilicate base, Zhur.prikl.khim6
34 -ao.10:2295-2302' 0 161. WMA 14:U)
(Hydrogenation) (Cataly3ts)

s/846/'62/017/000/00
1/002
E071/E135
AUTHORS: Lozovoy, A.V.p Muselevich, D.L., Ravikovich, T.M.,
Titova, T.A., and Cherkasova, Y.F.
TITLE. A two-stage scheme for the production of chemical
products by hydrogenation of tar from the Cheremkov
coals
SOURCE. ikkademiya nauk SSSR. Institut goryuchikh isko]~ayemykh.
Trudy. V.17, 1962. Khimicheakaya i termicheskaya
pererabotka topliva. 174-181.
TEXT: This is a continuation of the previously published work
in which the possibility of production of 'various compounds and
semiproducts from the tar produced by semicoking of the above coals
was demonstrated; namely, that by liquid phase (at 300-500 atm)
and high temperature vapour phase (at 75 atm) hydrogenation, 3i-37%
of various chemicals. 37-51% of a high quality motor fuel and
18-251~ of gases (CnH 2n+2-, C1 - C4) can be obtained. In the
present work a gaseous phase hydrogenation directed towards the
production of chemical products Instead of motor fuel was carried
Card 1/3

A two-stage scheme for the production... S/846/62/617/000/001/002
E071/E135
out in a 3 litre laboratory reactor. Liquid phase hydrogenation
products of the tar boiling up to 300 *C, obtained under works'
conditions, were used as a starting material. Phenols and a major
part of nitrogenous bases were removed before the processing.
The hydroaromatisation was carried out at 75 atm, hydrogen supply
of 5.5 itioles per mole of the raw material, and a temperature of
510 OC in the presence of a technical catalyst ~'1003 + A1203, at a
volume velocity of 0.7-0-75 kg/f/hr. operating period; 100 hours
with one stop after 67 hours (without regeneration of the catalyst).
According to composition and yield analyses the activIty of the
catalyst remained approximately the same throughout the operating
period; 71-74~o of liquid hydrogenated products, 3.5-4% of water and
23-25~` of gaseous hydrocarbons (C nH 2n+2' CI - C4 ) were obtained.
A high degree of aromatisation (86.7~9' of aromatics, including
38.11"0' of monocyclic and 48.60,fo bicyclic and condensed and 13.3s of
naphthenic and paraffinic hydrocarbons) was achieved. over 825' of
the liquid products boils below 250 aC; this fraction does not
require a further hydrogenating treatment and represents a
Card 2/3

A two-stage scheme for the production... s/646/62/017/000/()01/0021
E071/E135
finished raw material for the separation of arontatic. hydrocarbons;
the residue boiling above 250 *C must be returned to hydrogenation.
By a two stage hydrogenation treatment of the tar combined with a
preliminary separation of phenols (C6 - C8)'and bases and with
other processes, 62-660,o of valuable chemical.contpounds and
semiproducts (aromatic hydrocarbons C6 C8, phenols C6~ - C8g
naphthalene, monomethylnaphthalenes, solvents, etc), 33-37% of
gases Cn112n+2 can be obtained with a hydrogen consumption of
5.7-6.o% on the weight of the tar.
There are I figure and 2 tables.
Card 3/3

s/846/62/017/000/002/002
E075/EI35
AUTHORS: Lozovoy, A.V., Nuselevich, D.L., Ravilcovich, T.M.,
Senyavin, S.A., Titova, T.A., and Cherkasova, V..F.__...
TlTIE: Silica-alumina based catalysts for high hydrogen
pressure hydrogenation
SOURCE: A.kademiya nauk SSSR, Institut goryuchikh iskopayemykh.
Trudy. V. 17. 1962. Khimicheskaya i termichesk6ya
pererabotka topliva. 199-211.*
TEXT. Silica-alumina catalysts activated with HF and
described previously (A.V. Lozovoy, D.L. Muselevich, T.N. Raviko-
vich, S.A. setnyavin and V.F. Cherkasova, Zh P Kh, 34, 1200 (i961))
have insufficient stability at 300 atm, and 500-510 OC during
hydrogenation of coal tar oils. The allthors therefore investigated
the activity and stability of the catalysts at 600 atm and
470-505 OC during hydrogenation of coal tar oils from which the
most valuable phenols and N-compounds were previously extracted.
The new catalysts were based on HF treated silica-alumina with the
addition of a few percent of oxides and sulphides of Cr, Zn, Fev
Ni, and traces of W or Mo. The activity of the catalysts was

Silica-alumina based catalysts for high... s/846/62/017/000/002/002
E075/EI35
investigated in continuous vapour phase hydrogenation. Most of the
new catalysts were found to be highly active and superior to such
industrial catalysts as WS2 - silica alumina (no.6434), M003-AI203
(no.736o) and K-536 type catalyst. The most active was catalyst
no.66 - askanit (Askan clay) activa'~ed with HF (73-35',t) containing
oxides and sulphides of Cr (2.91,D), W (0-75vc), Zn (5-950.
Hydrogenation of coal tar using this catalyBt was carried out for
3 to 4 hours under 600 atm and at 501-505 C. The liquid products
contained predominantly aromatic hydrocarbons,and the gaseous
products - ethane and butanes. The advantages of catalyst no.66
are. 1) its complexity of action permitting use of one catalyst
in place of the three used previously (W52, wS2 + silica-alumina,
~!003 + A1203) and one hydrogenation stage in place of three stages
previously, i.e. preliminary hydrogenation, reforming and
dehydrogenation under pressure; 2) possibility of direct
processing of coal tar products; 3) high space velocity of the
hydrogenation - 1.5 to 2.0 in place of 0.5-0.7 used previously);
4) small content of expensive W (0.75050 and exclusion of Mo.
There are 1 figure and 5 tables.
Card 2/2

KRICHKO, A.A.; MEZHLUMOVA, A.I.; PALICHIKOV, G.F.; TITOVA, T.A.; Prinimali
uchastiye: CHERKASOVA.. V.F.; RAVIKOVICH, T.M.
Hydrogenation of arazatized petroleum crude without catalysts
for obtaining naphthalene and other products. Nefteper. i nefte-
khim. no.9:30-33 163. (MIRA 17:8)
1. Groznenskiy kreking-zavod, Groznenskoye upravleniye noftepere-
rabat3nrayushchey i neftekhimichemkoy promyshlennosti i Institut,
goryuchikh iskopayemykh.

MICHKO, A.A.; LOZOVOY, A.V.; MZHLUMOVA, A.I.; PALICHIKOV, G.F.; RAVIKO-
VICH, T.M.; TITOVA, T.A.; qjtERKA5OVA,___V.F.; Prinimali uchastiye:
MUSELEVICH, D.L.; SOVETOVA, L.S.; TSITRON, I.L.
Obtaining naphthalene from straight-run fractions of the Anastasi-
yevska petroleum. Nefteper. i neftakhim- no.100-8 163.
(NIRA 17:2)
1. Institut goryuchikh iskopayemykh AN SSSR, Groznenskiy kreking-
zavod i Upravleniye neftepererabatyvayushchey I neftekhimicheskoy
promyshlennosti.

KRICHKOP A.A.; LOZOVOY, A.V.; TITOVA, T.T.; Prinimali uchastiye:
RAVIKOVICH, T.M.;
Role of water vapor in the produ,ltlon of naphthalene from
petroleum raw stock. Nefteper. i neftekhim. no.11:18-21 164
(MIRA 18:2)

RUB111, Boris kdaimovich, prof~- CPZIKASOYA, VJ- red,,,! VORONINA, R,L,
tekhn. red. I-------------
[Course in plant pbysioloMr] Kurs fiziologii rastenii. I-,oskva.
Gos. izd-qo "Vysshaia shkolay" 1961, 583 p. (MIRA 15:6)
(Plnnt plkvviology)

BURLAKOVA, Yelena Vladimirovnn; VLADIlXI;'-.'OV, Yuriy Andreyevif.-i'l;
KOLIS, Ollga Romanovna; KRIGER, Yurly Arkadlyevich;
KUDRYASHOV, Yuriy Borisovich; LITVII,, Feliks Fedorovich,t
KOI.IAZYUK, Vasiliy Grigorlyevd-ch; CEERKASOVA, V.I.P
[Laborntory work in biophysics] Mnlyl praktlkiur, pro
[By] E.V.nurlakova i dr. Moskva, Vysshala ohkola, 1116~4.
407 P. (I-IJEIA

T
TOLKAGHEVSKAYA, Nadez41;d:t Filliplovna; KAPLfiliSKIY, S.Ya., prof.,
otv. red.; CHERKAS.OVA, V.I., red.;TSUKEM11K, I.A., red.;
TIKHOMIROVA, S.G., tekhn. red.; GUSIKOVA, O.M., tekhn.red.
[Development of the biochemistry of animals; a short
historical outline] Razvitie biokhimii zhivotnykh; kratkii
istoricheskii ocherk. Moskva, 1--d-vo AN SSSR, 1963. 96 p.
(MIRA 17:1)

GORZHKOVSKAYA, Sofiya losifovna;Sp;~~4POVA, V.I., red.; NURASPOVA,
V.A., telchn. red.
[Disinfection in veterinary practicel Dezinfektsiia v uslo-
viiakh veterinarmi praktiki. Moskva, Vysshaia shkola,
1963. 359 p. - (MIRA 17:3)

PASYNSKIY, Anatoliy Germanovich; CHERKASOVA, V.I., red.; GRIGORCHUK,
L.A., takhn. red.
(Biophysical chemistry] Biofizicheskaia khimiia. Moskva,
Vysshaia shkola, 1963. 432 p. (MIRA 16:9)
(Biophysics) (Biochemistry)

RIJBIN, Boris Aniaimovich, prof.; CURKASOVA, V.I.) red,; YEZHOVA,
L.Le., tekhn. red.
[Course in Plant PIWSiOlOgYl Kurs fiziologii rastenii. Izd.2.
Moskva, Vysshila shkola, 1963. 597 p. (MIRA 17:3)

BOYEVA, Mariya Nenova; CML4.%VAp V.I., red.
[Immunological tucW dpr6cancerous changes in human
breast tissue] . 2~ .. *skoe izuchenie predrakovo
i=enennoi tkani mol6t '14-zheleq cheloveka. Moskva,
Meditsina, 1964. 96 p.- (MIRA 17:11)

fed.
ratcr-y work ir, nUCI.E!- 2 ac-J Qz-,
abc
simil 21-3

DYIT;~FY---A', li ' - V -, '. . . e~
1. ('. i. ~ 1 , " 4.
1 PIWsic," of h I rho r nervc-olS ,-~,tivl ] Fiz i ,)-' , C~ I i a
-iTysshei neninoi doiatellnost.i. lhloshu, Vysohaia shk(,-In,
19614- 2,65 1). 17.0)

KRETCFVICH, Val'tsOv Leonovich, Prof.; -GLJ141~~SOVA, V.I.-I red.
(Principles Of plant biochemistry] Osnovy biokhimii
rastenii. Izd.4., perer. i dop. Moskva) Vysshaia shkola,
1964. 585 p. (MIRA .17:12)

LATYANIZOVA, Lyudmila Vladimirovna;,qWKASOVA, V.I., red.
[Lectures on the physioloa of thn nervous nystem! loki.sAl
po fiziologii nervnoi sisterW. Mosk-va, Vysshala shkola,
1965. 311 P. (MIRA 18:5)

SVISTUNOVO G.A.v ifizh,; CHERKASOVAp V.P,
i .1- 1-11-1--.1--l- ---
J.
Cutting and drilling concrete and reinforced concrete. strol.
i dor, mash, 10 no,8125-28 Ag 165. (MIRA 18sq)

CHERKASSKAYA V,M,
cf)
Extraordinary weather phenomena in the U.S.S.R. in 1958A,'nd 1959. 4
Trudy TSIP n0-122 161. (Meteorology) -(MIRA 14:1)
1
t
., A

CHERKASOVA, YE. F.
"Experiment to Study Dust and Smoke Contents of Atmospheric Air in the Area of the
First Moscow Order of Lenin Medical Institute Clinic to Wcrk Out Sanitary Measures."
Thesis for degree of Cand. Medical Sci. Sub 20 Jun 49, First Iloscow Crder of Lenin
Medical Inst.
Smr,ary 82, 18 Dee 52, Diss!Zrtations Prese for Degrees in Science and jin
teA giije ring
P p_- -
JjLbopcow in 1949. From Vechernyaya Moskva, Jan-Dee 1N+9.

CHERKASSKAYA, V.S.
Effect of the substratum on the biochemical characteristics
of the -lichen Evernia prunastry (L.) Ach. Bot.zhur. 50
no.7:979-981 Jl 165. (MIRA 18:11)
1. Leningradskiy tekhnologicheskiy institut kholodillnoy
proM,shlennosti.

tAE
um by Odw. f. N. Popow. R.F. q*kuav. and 0. L.
'T 17~ lat MGM" Mod Inet.). -Gith"m i sexii.
72M 16-2D.-Comm 6bm 0.004 me.A. cannot
be I I , W by odor. At 0,00"Aft hml It w" detwtable
bw am* pwW. 0. U. Komokpoff

POIZAKCIV,, Illya Mikhaylovich; CHMKASUVA, V.I.9 red.; GOROKHOVAq B.S.,,
tekhn.red. ----
[J.B.LaTna ck and the theory of the evolution of the organic
world] Zh.B.Lamark i uchenie ob evoliutsii organicheskogo
mira. Moskva, Gos.izd-vo "Vysshaia shkola,n 1962. 265 P.
(IAMA 15: 5)
(Lamarck, Joan Ba tiste do., 1774-1829)
a~
(Evolution

KUDRYASHOV,, Yuriy Borisovich. Prinimali uchastiye: KOZLOV, Yu.P.;
SUMARUKOV, G.V.; TOLEACHEVA, Ye.N.; RYABCHENKO, N.V.;TAFIJSOV,B.N.,red.;
CHEMSQVA,__Y.I., red.; MURASHOVA, V.A., tekhn. rod.
[Laboratory work in general biophysics in eight volumes]
Praktikum po obahchei biofizike v vosImi vypuskakh. Pod
obshchoi red. B.N.Tarusova. Moskva, Vysshaia shkola.
No.7. [Radiobiology; radiation injury of biological objects
under the effect of a single whole body X-ray or gamma ir-
radiation] Radiobiologiia; luchevoe porazhenie biologicheskikh
ob"ektov pri deistvii obshchago odnokratnogo rentgenovskogo
ili gamma-oblucheniia. 1962. 273 p. (MIRA 16:4)
(RADIOBICLOGY-LABORATORY MANUALS)

VIASYUK, P.A., skademik, otv. red.; GARYWSHA, M.A.[Harkusha, MI.A.1,
red.; ZOR114, I.G.[Zorin, I.H.], red.; KOZIY, G.V. [Kozii,H.V. bprof.
red.; KUYSIN., M.V., kand. sellkboz.nauk~ red.;,-CIIERYASOVA, V.O.~,
kand. fiellkhoz.naukt red.; YUKJ1IJ/,CHUK,
sellkhoz.nauk, red.; LISOVICHENKO, Ya.V.[Lisovychenko, IA.V.],. red.;
VIDONYM, A.P... tekhii. red.
[Increasing the productivity of natural forage lenads in the
Ukrainian S.S.R.~ transactions of the session of the Department
of Agricultures of the Ukrainian Scientific Research Institute of
Agriculture] Pidvyshchannia produktyvnosti pryrodriykh kormovykh
uhid' Ukrainslkoi RSR; pratsi naukovoi sesii Viddilennia zemlerob-
stva. Kyiv, Vydavnytstvo UASM, 1960. 185 P. (MIRA 15:7)
1. Prezident Ukrainskoy akademil sel'skokhozyaystvennykh nauk (for
Vlasyuk). 2. Sekretar Kiyevskogo oblastnogo komiteta Kormunistiche-
skoy Partii Ukrainy (for Garkusha). 3. Chlen-korrespondent Ukrain-
skoy akademii sellskokhozyaystvennykh nauk, zamestitell rrdnistra
sells'kogo khozya-ystva MEE (for Zorin). 4. Nauchno-issledovatell-
skiy institut zemledeliya i zbivotnovodstva zapadnykh rayonov
USSR (for Koziy). 5. Ukrainskiy nauchno-issledovatellskiy insti-
tut zemledeliya (for Kuksin). 6. Poltavskaya gosudarstvennaya
sel'E!,kokhozyaystvenns:ya issledovatel'skaya stantstya (for
Cherkasova).
(Ukraine-Pastures and meadows)

CHERKASOVA, Ye.D.
Malignant tumors in children. Trudy Inst. klin. i eksp.
khir. AN Kasakh. SSR 8:95-98 162. (MIRA 17:7)

-,, , ,!, 0'. 'i!"! , C, . 1: .
, N.F.t U""I~
-, T 1 , .,. a I - L, ' I
=_M-Kr. -~-
~ I - - -- .*,,, of- data through h 011"T1''
. -,-3 f or .. - g S 165. (mir,.A 18:9)
..: 11- I no 0-58
,~:rrlaphy c-InEll"Iel- Zlektrosviazl lc - 9: -'
i. :,~ I " W

Kli-CV1,
2. USSR (6CY,,)
"The Questim of the Electrochemical 1"dio-darilzing, of Organic CompoLulds",
Zhur. Obshch. Khim. 9, No. 19, 1939. Institute of Chemical Pharmaceutic
(Tonkoy) Technoloa, moscow. Received Ll Maly 1.39-
9. IM Report U-1626, 11 Jan 1952.

004
0 0
00 C
son
**a t
o*
00.1
0o0
00-3
flow
0 0 0 0 0 0
0 0 w
a 34 a 36 v 38 S 4 it
I'lloctists A.D VA"t41,11 ..Ott
The elearoikimical tatmuttwo of the
Peap into orpsk compounds. 11 . Thl,
of the Nocreawtv group into aromatic &mines. AL-1,1-
Cherkaftsvit. 1. Wyofenko autl N. N. NleVnikov. J.
C;FG;'-VWiW_- k1 S. S. R.) 10, 1373-410140). cf. C. A.
34. WMI.-The lwvyimsly dm7ibed incibod onts used
for the prefin. Ul the thiocyanate ded". of wetkyl.. *1A.W.,
yibe"S3416-
Mae. dibid.Wouslixo,enthromilkatidandV.mdhWamitiranilk
acid. Ila substitution occiarred in the p-pamition. excep-
tions being the 2 acids where the substitution omm"ed in
the kv-povition; the deriv. of PhNflus was not wpd. be-
cause of deempa. The ykid of the thkIcyanate derivs.
ul ftvundwy amines was about 41-60%. and that 111
tert-&ryamines8de'. The yields of the detivs, of tb*2
26. . were 54 and I A. A. Podgorny
0 0
41411
~90
-00
.410
gas
me*
age
rx a 0
too
see
81*0
1300
4141114111
1900
"AA
C
A WYALLVIIIACAL LFTINATWO CLASSIFICAIN"
loom NO.&AT
S&W" -A ai, 041 084481 ow OW. all
I"'*
I F AI 1 6 P vr An A I a 64 o N a v N 5 a
jL-S AV 00 IS k9 I FA dR4
I. a & to It a 19 a a a n F -
0 0 0 0 * 0 4 0 a 0 0 0 0 0 0 0 0 0 0 0 0 0
0 wis 0 0 * 0 00-000 4 0 Go 00 0 go 9 sees 0 090 0 :1A

A
0*
00
00
'3
v
Z M.
K ti V(I
-kKIMI AOO P40M41 W04-
sl%*stma" thWya&aU*o a arpak compoubda.
W. 04Wbditaud aroosatic auslaps. N. N. Alti'aikov
and It. A I I M. U. S. S. R-) 14,
llazlq PAISM Vmnwy); d. C. -A - 35, 30151.-
The t. W ft conducted in a Cu ve"d sawt as the
tuode. the tcrnp. used
Cathode. with a rotating vaphite I
was - 51; the c. d. on the &-We raulsed, front O.W -0.05
am "' It ws" used. ji-Toluidiae
ciz.; no di
Paoli treati. NIIA"T. 2"esc, coned. llCljkUd33Cc.*q.
3~ with 2 amp.-hro. of mirterat. yielded. after
dila. and rcft for 1.5 hrs.. 2-ainizo-G-snetbylbenso-
'91 1.5 S. anWint, 2.7 X.
1411,CN5 4 cc coned. JiCl and 12 cc, UtOR40 cc. Jlj0
v " -M.
" c 5fl. - '
f
ly uj;j.;,j&.W.I, W-
*&t obtained, When 2.5 ampAirs. of
curtent was P*mcd through 1.08 S. P-14NUIX(hilt,
NIS. 5 cc. conL41, JICI And 20 cc, E101-1-0 cc.
w,asobtained Ft 4-wnino-3-thiixymnobensonle,
which, bested to 150% pvc 110% 2-atuina-0-cwbethaty.
ben2abl"We. In. L404'. Similarly, the cofftq)ohding
261c cster, in. 2MI. was prrlxl. (min p-I I %'Cjt COMe
Lab- Organic Chem., MOSCOW InSt. Of Fine Chem. T,,bn,,lo
sy.
A I a - S L * MITALLUNGKAt LITIRAIM CLASSIVIC01001
I/ S1010110 Wit Q%V an
-00
1-00
-00
-00
-09
se 0
9 too
411
2 see
too
00 0
too
U 11 11 10 1 W M I 9M a 3 4! 1 ~
dac
0 o1: 0 :jib a 0 a 0 4. 0 0 0 0 0 0 0 0 0 0 0 0

OIW- W - W - W
I a b 13 1) Tj it W it )ill MA) bip)WIRS41 vi) U
F
4 j - 0 -%L~, j ~p (4v[
fl

Elvaluchvitilcal syntbosila of Of4anic C0121POU11,10 V. 0 i
Ilivitatillion tit selogkoeyonalvii. N. N. htrh%iL,,v o,,,l F. I
1
Nt. cl"IL't"na J111.1. Fine Chem. Tevit.. NI""ms) .1. :-00
ItUS-N(Wid)(iii liti-imil; vt
39, J1111. tit -,ilfq tit )ISVN ill 11tv
tit -g, Stilittall,V4 Ill the 411,41V 4.111111-atimnif
lva6 I,, Jim ooim 4 ns- A Vii vr,~I
-00
1111d vouldlilt'l 01111111,11i ti,lv ; 61
'
'
all'.1v WA, It.A.
1l, app. ua, 'wic'I
I -of
(P KI;t-CN. 30 tv~ 00
4p FtOll, WO Ill VC. 11,41 ~Vll- 0- It-dV9111 at f-~ 411400 41.

1101,' O.WS lkilil~-Nl, cm, 1,19 a filial 'if 1 2 Allip '00
; aft'l dillt. With %N4141 Itild V01, %%ill% I(f.0 1111-tv WA%
f
e
90 It file tractiall Ix lull it% al.n.r.
1,111 wills adtill. .4 1.13 R. emed. IICI and tile 114V 'd '-'0 V.
E10111 tile is 20" Much Se is fixtiled thililix tile
ti-141-tilml. O"Ollit tile ricellotIcs. vie. Similar tractioll 0
,ill, M."Wh at 0AI-OAK4 alsto.l.q. vm, flaw 211--, W
' jug*
((wist jw(i~ vilict). PliN11M.-
Ow do-bi derm. ill. AO 2
;xo

at 0.01-0A-1 atilix./sq. Cm., UIKIUI 100, I-M91A)4,1#nlNO-4-
' :
t JINI)II
(rpNOjr14-nO)brxsrflr. tit. W* (from lwtv. ether). )-
cqv. 11-i"Ir a tit Im a 41111ilar Yield 44 we
fit, 1-3 .1"', . m. V!',
SJ

1116t- of Fine Chemical Technology im. Lomonosova
Mosc
w t-0 0
.
o
,

10 nO 04 N It 91 0 if q it
0 0 *1* 0 0 a 0 0 00 0 0 0 41 r'so

t
Yv
14
Eb VIC
7, 0-1
0 io VY
;,,, JR I I
(D i-j C) (11 I-d
P, 0 C4 Ir, 1-i
o
,J3
ty
I'AI
ot 0
ItD,
V- 0 tk 15 0
ED o I` ct,
at
aj 0C' 0
C) It c..) 0
0 fu
0
Ci-
rr &
0
P, Vi C,
r) %5 ct j
0 V tD 0
10 OD Id 0 CA
I\) d
I- 1115
t-4
lK 1- 4 A
0

OAFRK~ qA C. f"t\ -

;~wlf !'~ low v :-vi";, stibsiourc-t V "IT 17,!,'; m4,fl,. lit. Nit lCI M 'T01 16111
Ah 0 ~ I 1.!,. -1 -.1 11 r, NVII lllillft~ 1 -111 opanols.
--r-
1
T gave Ph0(31,-(.'00. bit ]09 -10', 1 his (0.217 g.) st,,-
#
Q
;old V. M. Cbef I.offmumov it-IfIrd Mmdy lit 4.4 g. in
Ah;!a, .15, I.Mro NI
~'j
v-
l
I
7
i
i
1
7 hipi'll and 11"~ -Ill. (tcale't 10 -15 inin. with dry IICL
, -
-
l'o-
i
ont
m
. 1 y I I I I v t I t-v
-111 ty)
p thell lwalA (1 ('11 It sivatil 11:1111 IA firs.: neillification -with
11"Wl"d ik. was foluld it) N- a mroug aut'sti'Clic willi rel.4- 11cf, (!Xfll. lVilb li'lio, and tmilluelit of Ole acid cxt. with
hase garc AR17,
~ phenny)"cr-
opcu situriturc- of Ilmimlol wele couipide-ly late, 11, 171-'.," (oxalatto.,111. 103-5'). To 6 g. I-tnetflyl-l-
amllr'esio. llysirt'gmiatioll of EttNICII-.Cll~ 0.42 g. Mg, and 30 ml.
lir-M-1 ov,-r hl-CaCO. gave 46.0% 1-1,henyl-J-dirthyl- (Irv C-11--addrd -7g. AcCI:
1111-ijillpffif1daITI, b. 113-13,N' (flie teaction is tii~,rc rapid ill flit mixt. yirldvi'l 0.4 r,
MI.-S-All. Illml ill JA011 : hom,wr lit aq. soln. tht: prilicipal
' propyl aeffate, fit., 94--V (reziction rif the nic. W'itll 'tcyl
, .
- it) F '11 ;7 p
'Irtiou R eleavigt: U-N -t -T~tl-lz)- MAI 13t and
ChImidv. ditvvily gave Ow c"frespollililig Iti-I salt, m. 1715
,
M-NCHIC11,B7.11CI s,,tve 47."I'ro 0'), 'SiS110,11 1y
w(:go pi-epti. the follolviur cstcm: I-mtrth;4-1-
aminepoNnol. isninted ,.q no salt, ,I. 1f.2-3' - Ileating h,.j 07-91 (110
AIC-Nii At 804
Avith 33% aq. A
salt, in. 15 a 144-di'meth Ila in ina-
g'-lvc8O% 1-dtotellf ho 50-21'. whirli with emoaff, b: 1M-8* QfCl still, In i'sn'so r)*): 1-iviyl.
I 1
`
pro
'
-1-phrilyl-3-
111-iLl (frout Plif3r rind U) in 10,13 gave I-forth*4 v"
ii-lio (11
7
J-P ly .3
a
-I'laillitalprollyl 12cri'N' bi ll
It'.1 102-3,; 110 sali. lit.
1
still, in. 1-f1h)l -1-phen 14-3-ditlirthyla in ill"I"o y1
I-'tlfrnr and gave 957o I-Phoiyf-l- 1-
p,opinnale. b, 120-2" QICI still, ii. J11h31
1), 00-2", tit. 42-43*, the tryrpale, 1), 1.10-42* (11C4
salt, lll~ 1.11-U51);
1), 102-4', in, -19-50*; 110sall, lit. 151-2*. I~o' isolated as HCI sa)it, ill. 1321-3'. ohLairml

PrMpBr gave &-, ,, tit ino-
j.5%
cmicuriently witli P-hCFJ:C[1CJ[-jVAfe:, It. QICJ jah.
proponol, bi 96-7% 731,1, 1.5222, dw O.W.M. 11C1 salt, ill-
' m. 183-3.5;); cittra-
152-3* (RNTg1 gave but 27~
/'o yielfl). Dt3hlgBr gave 90% male, bolated an 11b salt, rn~ 16-3-4"; cormsponding hydro-
in. 43-4' QICI tiritamale, inolated as 110 salt. ni. J-prop,)4-1-
14-9-50"); PhCJ1,MgCI gave 70% I-phtnyt-1-benryt-
' ardate, b, 114-15" 1.
(HC1 salt, in. 15G-7
o-dimrlhylatninoprapanal, tri. 70-2 JAMS, illm O.RSM3 -(11CI salt tit.
nino-4-limmnone gave a good
PliLiaiii2-metb,6-1-"Imetfj~,la. plicni'l S-dirmthyIntnitioprop~J propittrate., b, 1,n-1% ttg.o
yield 4.! 1,4952, rl.~ O.U.S01 (11CI salt, m. 152-3'); 1-prapy?-I-phfx~lf-
hl.s it inopr,,p~j 1!(7 $4 ill

Vc P,

12-14 Piowlt. lit. 167-8
"it' 1.50M, tit$
methylandriopropyl arelate, be., 101-2'
.
pirthylizinhiopropyl propio"alp., bi 11 (Ji (7 sail, ill. 170-
vrelalt
lt
~
1JCl
V
sa
, sit.
CI in *old
x
ZO), imlatud as
is also prepd. froin W~11~ Ac-O and asmall atuamit
of MiCO.-Mu dry berizene aftt'r =veral duys at room lenip.
.711c direct reactiou of tile amino tile, uith MCOCI in dry,
hlc,CO,g.3ve 60%
Theaminoale.
treatecl with Na it! diox-Mle, follm%vd bv DZCL gave M7.
lq~nzaaje, b~.. 142-
'A)'; 110sell, in. 156-S". Reactim) ~f tile aminuale. with

It
AeCl in C(H. in the pic5cuce rf Ali; GS", 1-.;sol
1-':1-3* UICI sall,
ln~ 172-3'); ii tit, reacti,;il is tull tit SA-90' the -tie. is
dvhydraw~l if, CPh C bt., 91-2.5",
ivlwse I1CJ 3aft )it. 1S1.5-2'. Similarly wore
I.,roplonatc,
In. ul.

7' (oxalutc, tit, 17(1--t')~ Dit"t iv:w6mi d tile ami~lo ale.
Ivill) HCOCI ill 1"1.0 gav'~- -1 0~1"
(1111ii,01"01,31 phoroxw(dale, HO 4'dt' tit. 179 SO'
1-1wazyl-j-pht-nyt ch'ilaw') it,a). ls(~
V- the hydroripmiwale, ui~ 111-2'.

ubstUne"
u 25
ridinoyrOP'% U s S 1%
-3-P%P~
phenyl j Gol. chrill.

TISSR/Orgaaic Chemistry. Synthetic organic Chemistry. E-2
Abs Jour: Ref Zhur-laiimiya) 1~lo 6, 1957) 19191
Auth,*.r Razarov 1. 1., Cherkasov"a~,M---,
Ti~.'-e Synthetic Anaesthetics. II. Complex Ethers 1-aldyll-l-
phenyl-3-(Ii-pyperidyl)-propane-l-oles. III. Complex ethers
1-phenyl-l-alkyl-2-methyl-3-diallcylaminopropane-l-oles-
OriG Pub: &',.. Obshch. J(himiyi, 1955, 25) 110 11, 1935-1942; 212o-
2127 -
Abstract; II. For the investigation of new anaesthetics from N-
pyperidylpropiophenone (I) by the action of Mg-organic
compounds were synthesized compounds of the type C5"10"-
CH2011P*6115) (R) OU (II). At the application of I in
the folm of the hydrochloride the yield reaches 78-96~.
By hydration of I is obtained l-phenyl-3-(N-pyperidyl)-
propanole-1 (III). Dy the action of chloranhydrides or
-1/11

USSR/Organic Chomiotry. Synthetic Organic Chemistry. E-2
Abe Jour: Rof Zhur-Khimiya, No 61 1957# 19191
H01 169-1710 (from acotono-othor); analogically i:j obtain-
od (5 hours lioatint-) II (R-R"0211:0, yiold 6111'j, b.p. 115-
1150/1.5 ru; 11C Ll.P. 200-201.1 (from acotona.-cliloroform).
A rdixture of 2.04 g. I (R-011 )1 2.8 cc 06115COGI, 0.3 Mg in
15 cc C6'16 is left standingl hours, huritcd on a water
bath 6 hours and then 2 hours on adding a portion of
other, in the precipitate is 'I-IC-II (R=C1H,,, 110--Ooi5), yield
755, m-P. 181-1830 (from acctono-n1c.). 'Analocically from
2.2 g. ! (R-4pT15) is obtained a base II (R= C2'f "I'-
11 . -
=
'1r), yiold-1.1 g., b.p. 1()O--170'/1 mm, m.p . C 176-178'
06'~ v~ -
(from acetone); from 2.2 g. 1 2.2 3-C61150C11,200C1,
o1 g. mg, and 16 cc abs. other aftor the separation of the
precipitate, dissolving it in a mixtnro of abs. alcohol
and acetone and partial evaporation of thc filtratc,
are obtained I Z. 110 11 (13-C If 71'-CT-f20C611r~), m-P- 10-
') ~?); from 2.'~ g. I (R=n-
1480 (from acetone -othyllcota o
Card 10/11

USSRArpnic Chemistry. Synthetic Organic Chernistry,
Abs Jour: Rof Zhur-laiimiya, No 6, 1957, 19191
0]5~ 117 )(5 ll~our~; hoatins in 0 H ) -0.7 9. IT (R=n-C 751171 R I=
r tz )- TTC' I.:. r. 10a
~5-5 , - " -1340 (from acAono-,Ahcr);* and from
0 7 (R--n=c4llc) -,I'= C05), b.p. 160-
1~7 7 p. 10,, 1050 (fr;m acetone).
PC,
Card

NAZAROV, I.I.; CMMKASOVA, Ye.M.
I
tic anesthetics. Part 3. Eaters of 1-phenyl--~-alkyl-2--
S;mthe I
-methyl-3-dialkylaminopropan-l-ole. Zhur.ob.khim. 25 no.11:
2120-2127 0 055. (MA 9: 4)
1.Moskovskiy institut tonkoy khimicheskoy tekhnologii.
(]Cstw~g) (Alaesthetici)

kegeler 0- SynihLsla of l-
'~hy?4 Piplid%. XXT'
c Tp e9, 1. N. Nazarov,
S. 1'rostakov. lifid N. 1. shvctsov~
-'U~.S.S.R. 25, tr4ruila-
kltion)~Sm CA..5n 9111h

XX4
P-a
y - -P Pori one. ar N. 11rogulalcov,
d me Nay.. '3v E. Cherl'a'(wit, I
Sll%,etzf)v (7 Oksbuh. ~ it ti"-?,=FR-557Mf 224,17.0s),
NN-as luatle, of 1:1
by cycllr tioll of propellyl isollr(I'voyl Lvione with prinutty amines
-Jk)-1-
a
nd . allon of the 2 . linethyl-4-piperidone Uith nl~yl
linlides. Renctions occur ~vith t1m cn1argcmvnt of molmul". By
tho action of calrbonyl compounds and formic acid on 2 SAl.
methyl-l-piperidone, ':! : ii yoofvd, sull.
stitut"I In Olk, I pa"4ition, Nvith alli'lucti.,l) Al 11i6 VV~ In
po.5,itlu.it 4. rA

q
H- or 4
am 0
7anod
ro~
eir
a'e e 9 ~ ~e
S~ , d
Q.-
". ' 19
n. n
.1k I ai~-l on th. -it g ~'_th i_
if
tin k
kd to th n'.t J~
t ~re
b, ed Th n-,1 tr
follm%ing 1-acctonyl-2 5-diniethyl-4-hydrt)xypil)eridirit-; I-
plicnacyl-2 5-dimetbyl4-hydroxypipcri dine. These sulkitituted
derivat.-v" had no anaesthetic powir.

NAZAROV. I.N. [deceased]; CHERKASOVA, Ye.M.,- MUM, F.F.; BABITSKH,
B.L.-, VINITSM. I-.Ye.-
Study of action of Ea7lalIWIwtinopropanols and aminopropiophanonegi
as accelerators in rubber vuloaniztion. Miim.nauk i prom- 3 n0-5:
678-679 '58. (MIRA 11:11)
1. NoskovakAy institut tonkoy khimicheakay takhnologii im. M.V. Lo-
monosova i lauchno-iseledovatel'Bkiy institut khImicheskoy promyshlen-
nosti.
(Amino compoundB) (Vulcanization)

7 2
AUTHORS: 1~3,zarov, 1. 11. (Deceased) , Cherkasova, Ye. 11,
TITLE- Sjnthetio Ane3thctizin~~ Compounds (S-intet-ichcsl:iy4~.3 cbezb,-ii--
vayu3:)chJ1yc veshche3tva) XXII. c~ 1-Ph2nyl-
-3-Dimetllylaminopro,par,e-l-Oier, (X'XII.
PDRIODICAL: ~.iurni-Ll Obshche,., T--'.-,iJ 19rG Vol. _23; Nr 1, pp.122-126(USSR)
ABSTRACT: In earlier publications a, rumbcr of compound eaters of
nYl-3-dialkylaninoprcpane:.-!--oles wa3 desoribed, soyme of wl-~ich
had a high anesthetizina activity; cs~iccially the pheno,,~Y,-,ce
tate of 1-phenyl-l-etl,Y!--3.,.dine'Llliylariinc;pr,-,3,~.n-c-,-I-Dle. In
connection with that it was, of interest to zyntliesize them
j,henoxyacetates of a-,id
to determine the dependaiacc- of theii physioloL,,-ilcal act-.vity
on structure. For this parpose snba t4i t-ut nd
tates of I -phenyl--3--dine thylumin oprc, pane 1--oles were
which have different substituents in the benzene nucleus c4
-the phenc).yacetate Croup. For the purp,-se of
Card 1/3 'the anesthetizing activity tho authors also synthesized

Synthetic Anesthetizin(- Compounds. XYII- Phon'--vace-r-IteS Of
-Dimethylaminopropane-1-Oles
esters fron suberic acid and amino alconols (C-~-~
where R = 11). These ir-itial produ-3bs veze, as hsc~ibcd
earlier, synthesized accordin-.- 1'o 11annich froim aceto-ol,~or-ne
and dimethylamine with a subso-'-'1ent reduction of P-diriethy---
aininopropiophenone produced on that occasion, or ac-or;1irL
to Gri!-nard (see formulau). The phermacolo-ical inves,
of the obtained esters (II) as chlorohydrates was
in the laboratory of Tfaashhovskiy, 11, D. where tha subeiic
ester of 1-phenyl--3--d--,-,ietilyla.,.-,Inopi-opapol..'., the p.-nit-cc-
benzoate and the iii-crasoxzyacntate c-f
mothylaninopropanol-1 shoymd an exte-mal
activity. The p-cresoxyacetat:~ and Lhe
tate of the tertiary Lmino a1r:011ol (I., R = C Hr.)
to their activity approach d-1nain. Ii musts ?I O?ieuer, bp
ed out that their aclivity abruptly de--reases af-ucr
zation. There are 8 references, 3 of which are Slavicr
ASSOCIATION: Institute for Finn Chemical TeohnoloCy imeni ", V, Lomorz~'Z-ov
(Institut ton'-oy hhimicheskoy tokhnoloC-'4 im, E, V, Lo::icroscv-,
Card 2/3

7-9- 1 -,26/0'3
Synthetic Anesthetizing Compounds. XXII. Phenoxyacetates of I-Phenyl--3-
-Dimethylaminopropane-l-Oles
SUB14ITTED: December 14, 1956
AVAILABLE: Library of Congress
Card 3/3 1. Chemistry 2. Anesthatios-Synthetias 3. Phenoxyacetates

-~,7/63
i
AUTHORS: Nazarov, I. IT. (Decoased), cherkasova, Ye. 14. Chan Chom FL~?Rr-
TITLE: Synthetic Anesthetizing Compounds (Sinteticheskiye obe-.boli.-
vayushchiye veshchestva) XXIII. Phenoxyacetates of 1-Phenyl-
-2-Methyl-3-Dialkylaminopropanol-1 (XXIII. Penoksiatsetaty
1-fenil-2-metil-3-dialkilaminopropan-l-olov)
PERIODICAL: Zhurnal Obshchey Khimii, 1958, Vol.28,Nr 1, pp.126-133(USSR)
ABSTRACT: In connection with earlier papers in which hiphly active
anesthetics had been found under the phenoxyacetates of 1-
-phenyl-3-dialkylaminopropanols-1 the authors synthesized a
number of phenoxyacetates of 1--phenyl-2-methYl-3-dialkylami-
nopropanols-1, represented by formulae (I) and (II), in order
to examine the action exerted by the methyl group in the pro-
panel chain upon the physiological activity. The favorable
influence of such a ramificati(o in the alkanolamine chain
upon the anesthetizing action of their compound ethers was
already earlier demonstrated. The initial products; i.e.
1-phenyl-2-methYl-3-dialkylami-nopropanol-1 was, as earlier.,
synthesized from propiophanone according to Mannich. The
aminoketones (III) forming in this connection were by bydro-

M'Js Y~:'
AUTHORS: Nazarov, 1. N.,(Deceased), Cherkasova, Ye. 79-2-3,3/6,';
Chan Chon Khvan,
TITLE: Synthetic, Analgesics (Sinteticheskiye obezbolivayushchiye veshch-
estva). XXIV. The Esters of the 1-Phenyl-2,2-1)i;aethy1-3-Dia1-
kylaminopropane-l-ol (XXIV. Slozhnyye efiry 1-fenil-2,2-dimetil-
-3-dialkilaminopropan-1-olov).
PERIODICAL: Zhurnal Obshchey Khimii, 1958, Vol. 25, Nr 2, pp. 452-46o (USSR)
ABSTRACT: Aminoketones are obtained from isobutyropiienon according to the
reaction of Mannikh which by hydration are transformed into the
corresponding secondary aminoalcohols in order to then be trans-
formed into tertiary ones with the Grignard r~~agent. Dii:lethyla-
mine and piperidine served aa sesucondary ataincs. The obtained
aminoulcohols were transformed into the correspon(~in,~ ester3
mentioned in the title by the action of acid halogen-anhr&rides.
The latter were subjected to pliarLiacological investioations in
order to classify their anaestetic effect. Chlorine hydrates
were used because of their water solubility. The results are
given in comparison with dicaine in the talbe froQ which it ap-
pears that all compounds have a high anaestetic effect. PhE.~n-
oxyacetate is most effective the activity of which is similar
to that of dicaine, it, however, has a considerably lo-ner toxi-
Card 1/2 city. This preparation can be sterilized in a solution of o,5,,

/ D ,
Synthetic Analgesics. XXIV. The Esters of the 1-Phenyl-2,2- 79 -2-3-~~/','
Diinethyl-3-Dialkylaininopropane-l-ol.
and does not cause modifications subcutaneously in a ooluti,;n
of 1-2,,J. Precise data on the sZ~nthetized esters of the 1--h-c-ny-1-
-2.2-diiiiethyl-3-dialkyla with branched -.)-rc~,anol
chain are given as well as of the interTMediate products obt:-.-ined
(aininoketones and aminoalcohols with dimethylamine- and piperi-
dine residue) and of preparation methods. There are 1 table, ~,n(~
7 references, 2 of which are Slavic.
ASSOCIATION: Institute for Fine Chemica-1 Technology imeni M. V.Lomollosov,
;:Loscow (lZoskovskiy institut tonkoy kiiiiaicheskoy te'.~hnolu,71ii
imeni L,.V. Louonosova)
SUBMITTED: December 1i;, 1956
AVAILABLE: Library of Con-ress
Card 2/2

50) SOV/153-2-3-11/29
AUTHORS: Nazarov, I. N. (Deceaged). Cherkasova~ Ye, M.
TITLE: Synthetic Anesthezising Substancee. XVII. ~-Phenoxy Fropionates
and Benzoates of I-Phenyl-2=methyl- and 2v2-Dimethyl-3-(N-PiPeri-
dy!) --propan-1 -ol
PERIODICAL: Izvestiya vysshikh uchobnykh zavedeniy. Khimiya i khimichoskaya
tekhnologi.va, 1959, Vol 2., Nr A.,, pp 369-373 (USSR)
ABSTRACT: In earlier papers the author reported on the synthesia of
phenoxy acetates of some substituted P-amino propanols (Refs 1, 2).
Among the compounds of this type several produce strong an-
esthezising effects. For the purpose of explaining the influence
some
of the acid residue on the physiological activity
p-phenoxy
propionates and benzoates of 4--phenyl-2-methyl-3- N-pi eridyl)-
(
p
and 1-pheny-,-.-2.2-dimethyl.-7.~'.N-,piperidyl).-propan.-l-o1 with the
following structural formula were synthesized for the first
timet
H. C H CH C H
11
6 5 6 5
1
~~N-CH (J) < H -~~-R (11)
2 2 1

Card 1/4 1
CH3 6OR7 b1i3OCORI

Synthetic Anesthezising Substan;eB. SOV/157-2-3-11/29
~-Phenoxy Propionates and Benzoates of `,-Phi-,nyI~-2-.methy1- and 2~2-Dimethyl-
-3...(N,-piperidyl)-propan,,,!.:.,,I
The substituted propan.,-Iq vhfch were used as initial products
vere produced from the corresponding amino ketones. This syn-
thesis proceeds either ove-: tertiary amino propanols (in the
reaction with Grignard Peagentle) or over secondary amino pio-
panols (in oatalyt~... hy-~~.-g=,iia--Jon). The thus obtained amino
alcohols were transformed -_,nto -Che benzoatee and the pheno)W
propionates, respeetiv&.~y, by the action of the corresponding
acid chlorides. These riac.4-oaa prooeed acccrding to the
following sehemet
V R R
C J1 C-OH C H I" -H 6-a C H 6-OCOR"
6 5-1 H, 6 5-1 0 5-1 6 5-1
R' -CH R'1~000 ~C-CH
RII-C _CH R"-f.-CH, c,,C -
3 1 3 3
nH
CH H L.
1 2 C, 2 1 2 2
N N N N
Card 2/4 Q 'IV

Synthetic Ane3thezising Substances. SOV/153-2-3-11/29
NIPhenoxy Propionates and Benzoates of I-Phenyl-2-methyl- and 2,2-Dimethyl-
3-(N-piperidyl)-propan-1--ol
The following compounds with formula (I) were produced: R - H,
R, C H and C H OCH CY, R = CH R' = C H and C H OCH CH
6 5 6 5 2 3~ 6 5 6 5 2 2i
R C H RI = C R and C H O('F-,CH The compounds synthesized
2 59 6 5 6 5 ~ 2-
with the formula (II) had the following substituents: R - H,
R' = C 6 H5OCH2 CH2; R - CHI, R' ' C05 and C 6H 5OCH 2CH 2; R - C2H5
RI = C H and C H OCH CH,.. Most of these esters were isolated
6 5 6 5 2 2
in the form of hydroohlorld~,,-. The benzoate with formula (II)
(R = C 2 H5~ R' = C6H5 ) could be obtained only according to the
method by Houben (Ref 3) by th--- a,~tion of methyl magnesium
iodide 0 H C H
12 5 12 5
C6 H5- L;-UJI C6R5-C-OM-- C6H5-Y-OCOC 6H5
CH Mgj t C-H-COCl UU -kI;-L;ti
CH ~-CH 2 CH ~,-Cil
3-1 3 3*-! 3 3
CH Uh
2 2
Card 3/4

Synthetic Aneathezising Substances. 3OV/15'-'-2-'-4-11/29
11-Phencxy Fropionates and Benzoates c--' and 2,2-Dimethyl-
7, 11-piperidyl)-propan.-i-ol
In some cases the raactcr.. was irradiated with a
mercury lamp in order tc ircie-se the yield in the esterif-'-
cation. All esters syzitheuf7~=-d fc.:?,-a colorless crystals, soluble
in water, and insoluble '.r Only the hydrochloride of
~-phenoxy propionate of
dyl)-propan-l-ol could no', r- ,-ibtainaa in crystalline form. The
pharmaceutical investige."-Icns ~:f these compounds were carried
out in the VNIKhFI imen' '0rd-.:.-hon1'kf'.dze in the laboratory of
Professor M. D. Mashkovski -Y. The ;.-esults will be published later.
In a comprehensive pa--t all syntheses carried out
are exactly described and. -5:,~,duot'q obtained are characterized.
Chan Chon Khvan took part 'in experimental work. There are 3
references, 2 of which ar-?
ASSOCIATION: Moskovskiy institut tonkoy kh-i-m'--,theskoy tekhnologii imeni
11. V. Lomonosova .. KafedrL 02-ganJ-aheskoy khimii (Moscow Institute
of Fine Chemical Technology M. V. Lomonosov - Chair of
Organic Chemistry)
3UBUITTED: January 10, 1958
Card 4/4

5M
AUTHOR: Cherknsova, Ye. 11. SOV162-59-4-36142
TITLE: Synthesis of 1-Methyl-l-phenyl-3,3-dinethyl-3-dimethylamino-
propane-1-ol (Sintez 1-metil-l-fenil-3,3-dimetil-3-dimetil-
aminopropan-l-ola)
PERIODICAL: Izvestiya Akademii nauk SSSR. Otdeleniye khimicheskikh nauk,
1959, Nr 4, pp 753-754 (USSR)
ABSTRACT: This is a brief communication on the synthesis of the amino
alcohol 1-methyl-l-phenyl-3,3-dimethyl-3-dinethylaminopropane-
I-01 (1),R=CH3, not yet described. Mesityl oxide was the
starting point, according to the scheme:
CH 0 0 CH CH CH
3,,, HN(CH 3) 2- 11 ':,31/ 31"' 3 C6H5 JAgBr M
C11 /C=CH- &H 3 CH 3--C--CH 2-C-"-~, CH --UP.
3 R = CH 3 (11) 3
Ketoamine (II) could not be separated in a pure form because
it decomposes easily (Ref 1). Its hydrochloride was obtained
which could not be purified even by repeated recrystallization.
Card 1/2 It was immediately influenced by phenylmagmesium bromide.

Synthesis of 1-!-Iethyl-i-phenyl-3,3-dimethyl-3-dimethyl- SOV/62-59-4-36/42
aminopropane-l-ol
Attempts were made to esterify (I) (R - CH 3) but not a single
experiment yielded acyl derivatives. Numerous experiments
with chlorides of ali.phatic, aliphatic-aromatic and aromatic
acids were carried out under various conditions. The use of
ketone did not yield any expected acetate either. In most of
the experiments the initial product, amino alcohol, and rare
products of its dehydration were obtained. There is I
reference.
ASSOCIATION: Institut tonkoy khimicheskoy tekhnologii im. M. V. Lomonosova
(Institute of Fine Chemical Technology imeni M. V. Lomono-
sov)
SUBMITTED: August 22, 1958
Card 2/2

5 (3)
AMHORS: Nazarov, I N. Cherkasova,_Xe_._M. SOV/62-.c9-9-14/!,O
'
~.
S.
Yerkomaishvili:
TITLE: Synthotic Anoothatic Subetancea. Communication 28. &itor of the
Phenyl-alkyl-amino Ethanols
PERIODICAL: Izvestiya Akademii nauk SSSR. Otdeleniye khimicheski-kh nauk,
1959, Nr 9, pp 1605 - 1611 (USSR)
ABSTRACT: The synthesis of the substances mentioned in the title was car-
ried out with a view to the joint action of cocaine and vessel-
constricting agents. Following an idea of A. V. Vishnevskiy, the
addition of adrenalin to anesthetics was to be eliminated. Acyl
derivatives of phenyl-alkyl-amino ethanols are synthesized, and
their pharmacological effect is investigated. (The investigation
of the influence of the chainlength on the anesthetic- and ves-
sel-constricting effect will be published in a later paper.)
The synthesized substances are then compared with natural similar
derivatives of the aminopro-3anols, which also represent anesthe-
tics of various efficiency. A series of similarly composed
esters of the 1-alkyl-l-phenyl-2-diethylaminoethane-l-oles with
straight and branching ethanol chains (I) and (I!) were synthe-
Card 1/~ sized. The synthesis was carried out according to the following

Synthetic Anesthetic Substances. Communication 28. 307/62-59-9-14/40
Ester of the Phenyl-alkyl-amino Ethanols
scheme: basic substance was bromated phenacyl which was con--
verted into a-dimethylaminoacetcphenone (III) by dimethylamine
in ether. From (III) the above-mentioned compound is obtained
by the effect of the Grignard reagent, which can then be trans-
formed under simple conditions into various esters (benzoates,
phenoxyacetates,...). The branched-off compoundq were obtained
by similar st-4D-by-step transformation of the propiophenone.
The synthesized b:xtern formed in the shape of their hydrochlor-
ide; they are color.,~ss, well-crystallizing, wate:!-soluble sub-
stances. The preparations were gi7en to the NIKhFI im.
Ordzhonikidze - Laboratoriya prof. M. D. Mashkovskogc % (14!KhFl
imeni Ordzhonikidze --laboratory of Professor M. D. Mashkovskiyli)
for physiological testing. The experimental part of the article
Uescribes the conditions of syn,i3asis. The intermediate proiiuc'~s
of the synthesis were amino ketones (III), (V), and secondary
and tertiary amino alcohols with residues of diethylamines.
There are 21 references, 8 of which are Soviet.
Card 2/3

Synthetic Anesthetic Substances. Communication 28. SOV/62-55-9-14/40
Ester of the Phenyl-alkyl-amino Ethanols
ASSOCIATION: Institut tonkoy khimicheakoy tekhnologii im. M. V. Lomonosova
(Institute of Fine-chemical Technology imeni Y1. V. Lomonosov)
SUBMITTED; December 23, 1957
Card 3/3

5 (3) SOV/79-20-3-2/61
AUTHORS: Nazarov, I. N. (Deceased),,.Cherkasova. Ye. 11.
TITLE: Pain-killing Substandes (Obezbolivayushchiye vashchestva).
XXIX. Investigation in the Series of I-Phenyl--3-methyl-3-
aminopropanols and Their Acyl Derivatives (XXIX. Issledovaniye
v ryadu 1-fenil-3-metil-3-ai~-4.-iol~ropaiiolov i ikh atsillnykh
proizvodnykh)
PERIODICAL: Zhurnal obshchey khimii, 19'9, Vol 29, Nr 3, PP 724-735 (USSR)
ABSTRACT: Among the eaters of phenylalkyl-p-aminopropanols earlier
synthesized by the authors there were some possessing a re-
markable physiological acii.vity and one of the two methyll
groups in the a- and a,a-positions to the hydroxyl group in
the propanol chain proved to b-- ail inf luential f actor wi th res-
pect to the above aotivity. Only the influence exei7ted by
the methyl group in the 0-position (Refs 1, 21) remained ur,
clear. The authors were therefort- interested in aynthesizing
the esters of 1-alkyl-l-,plienyl-;--.iethy"--3-aL-.inoprolan -1-ols,
which had hitherto almost not been dealt with at all in publi-
cations (Refs 3-8). The initial proudet for the above pro-
panels was phenylpropenyl ketone w1hich was converted to
'
Card 1/3 P-dimethyl aminobutyropbenone (I~
and P-(N-piqer_Jdyl)-bi:tyro-

Pain-killingSubstances. XXIX. Investigation -4n the 10V/70-7~-3-2/611
.1 , 2, 1
Series of 1-Phenyl-3-methyl-3-aminopropanol3 and Their Acy! Derivati-ea
phenone (II) through dimethyl amine and piperidine (Scheme 1).
Compounds (I) and (II) are very unstable. It is of interast
that the analogous amino ketones with the CH group in the
a-position to the CO group or without it (III-VIII) are 're-
duced normally and give good yields of the corresponding amino
alcohols. The transition of compounds (I and II) into the
corresponding tertiary amino alcohols was realized by the
aid of organolithium- and organomagnesium compounds (Scheme 3).
Compound (I) with RMgX, however, led to but small yields of
the corresponding alcohols. The use of CH3Li and C2H,;Li in-
creased them up to 282,. Compound (II) reacted normaliy Pith
organomagnesium compounds (63-70,0f. yields of alcohols). In
both cases, according to the theory, two aminoalcohols (XI_XIV)
designated as a- and P-forms, could ne separated. The authors
referred to these a-isomers all those compounds, the hyd;o-
chlorides of which have lower melting points than those of
the corresponding P-isomers (Table 1). The aminoalcohols ob-
tained were converted into the esters by the benzoyl-, cin-
namic acid-, P-phenoxypropyl- and phenoxyacetyl chloride under
various conditions. This, however, met with difficulties and
Card 2/3 could be attained only by persistent drying of the crystalline

SOV/70-25-3-2/61
Pain-killin6 Substances. XXIX. Investigation in the Series of 1-Phenyl-3-
methyl-3-aminopropanols and Their Acyl Derivatives
ASSOCIATION:
SUBMITTED:
hydrochlorides in vacuum. Some eaters were also obtained by
the action of acid chloride upon the sodium- and magnesium
alcoholates (Scheme 4). Table 2 shows the yields of the esters
obtained in form of hydrochlorides. The infrared absorption
spectra of some aminoalcohols point to a strongly marked
intramolecular hydrogen bond. There are I figuref 2 tables,
and 17 references, 7 of which are Soviet.
Moskovskiy institut tonkoy khimicheskoy tekhnologii imeni
M. V. Lomonosova
(Moscow Institute of Fine Chemical Technology imeni Lt. V.
Lomonosov)
January 6, 1958
Card .'~/3

CHRMSOVA, Ye.14.
Chemistry of amino ketones. Structure of #-amino ketones andtheir
conversions in hydrogenation. Zhur. ob. khim- 30 no.9:2846-2849
s l6o. (MIRA 13:9)
1. Moskovskiy institut tonkoy khimicheakoy tokhnologii.
(Ketones)

CHEMSOVA, Ye.H.; YY2KORAISHVILI, G.S.
S7nthesis of 1-aryl-4-di met h7lamin o-l-butamolyr, and their estere.
Izv. AN SSSR Otd. khim. nauk no.10;1820-1824 0 6o. WRA 13:10
1. Institut tonkoy kbliaicheskoy tekhnologii im. M.V.Lomonosova.
(Butanol)

-CHERKASOVA Ye.M.; BOGATKOV, S.V.
Synthesis of some l~ra3:kyl-l-phenyl-2-diethyl-l-aminoethanols
and their esters,. Zhur. ob. khim. 31 no.3:81M15 Rr 161.
(MIRA 14:3)
0
1, Moskavakiy institut t nk khimicheakoy tekhnologii.
an O~
(Eth o1

CHERKASOVA, Ye.M.; YERKOMAISHVILI, G.S.
Synthesis of cyclohexyl-A-dimethylaminoethylearbinols and their
esters. Zhur.ob.khim. 31 no.6:1832-1838 je 161. (MM 14:6)
1. Moskovskiy imstitut tonkoy khimicheskoy tekhnologii im. M.V.
Lomonosova.
(Yethanol)

CHERKASOVAI Y?,M.; BOGATKOVO S.Y.
Methylamino- and methylbenzylaminophanylalkylethanol,3. izv.vyl;.-
uchelb.zav.;khim.i khIm.tekh. 5 no.2:284-288 162. (MM 15:8)
1. floskovsjciy institut tonkoy khimicheskoy tekhnologii imeni
Lomonosova, kafedra organicheskoy khimii.
(Ethanol)

CHERKASOVA, Ye.M.; BOGATKOV, S.V.
Progress in the field of local anestetic chemistry during the
last 10 years. Usp.khim. 31 no.8:963-988 Ag '62. (MM 15:8)
1. Moskovskiy institut tonkoy khimicheskoy tekhnologii imeni
Lomonosova.
(Anesthetics)

S/020/62/145/004/020/024
B110/B144
~UT'-OaS: __qherkasova, Ye. M. .-Yerkomaishvili, -G. S. , Makovskaya, T. N.
and Chao Ping-ko
TIT13: Synthesis of new types of silicon-containing arninaketones,
a-mino alcohols, and their asters -
PE'7:~'IIODICAL: Akademiya naiik SSSR. Doklady, v. 145, no- 4, i962, 641 - 844
TE._"~T: n-silico-neopentyl acetophenone (1),.n-silico-neopentyl proprio-
-phenone (II) and n-;ilico-neoDentyl isobutyrophenone (III) were obtained
'!:;y acylation of trimethyl benlyl silano in the presence of A101 or ZnCl
Good yields of hydrochlorides-of the (I-aminoketones IV '1111
n.(CH,)# SiCH, - CH& - CO - CH - CH, - N
N, commemis IV v vi Vil Vill
R' H CHI H CH3 CHI
_N N (CHS)m N (CHS)i NOO N0 N0 0
--rd 1/3

is of new ty.)es of
0
S/020/'2/145/004/020/024
B11o/B144
~-esulted from 1 and II according to 111annich .V, 4th dimethyl wmine, piperi ne,
a-nd These compounds were transformed to tertiary aimino
..,!,-:)ho.Ls IX XIII-accord4ng to Grignard:
OH R'
n.(CH))s SICH, - Colit - C - C11 - CH, - N
~Hj
X- IX x X) X11 X111
RO H H CH3 CHS CH,
N N (CHS)2I N 0 N (CH41 No NOO
I I is f-,rmed by deazination of IV and dep-minomethylation of V. The
:J-sez of '2e amino alcohols aere converted with the chloride of phenoxy
accz,ic z4cid to Dhenoxy acete-tes which may be used as 'Local anes..phetics.
-oiliri,~ points- 1: 94 - 95 Oc (1 mm Hg); 11: 114 - 1,170C (1, .5 mm H9)
120 - 1250C (1-5 mm Hg); n2o:. 1: 1.5260; 11': 1.5233; 111:
D
,QC'O.`-TIOJ. "."oskovskiy inst,tut tonkoy khimicheskoy tekhnolo-i- im. 11.V
Lomonosova (11;oscow Institute of Fine Chemical Technology
imeni 1.'s. V. Lomonosov)

5/020/62/145/004/020/024
Synt'hesis of ne,,,,, Types of ... B110/B144
~.arch 12, 1962, by. A. A. Balandin, Academician
S U 3:..1 T T 2 DMarch 10, 1962
Card 3/3

i. CLTZMOVA E. M. [Cherkasova, Ye.M.],- BOGATKOV, S.V.
Progress of local anesthetic chemistry in the last decade. Anal-ele
chimie 18 no.2:63-93 Ap-je 163.

CHEMOISOVA: ... Ye.M.~ YERKOMAISHVILI, G.S.; 1UROSIRUGHFMO, L.D.
On the two products of aminomethylation of cyclohexyl matbyl etone.
Zhur.ob.khim,, 33 no.4-.121+4-1246 AP 163. (MIRA 16-5~
1. Mskovskiy institut tonkoy khImicheskoy tekhnologii imeni
M.V.Lomonosova.
(Ketone) (Aminomethylation)

G YO.M.; YERKOMAISHVILI, G.S.
Eatera of phenylalkyl(4~.m6rpho3.ino)propanols. Zhur. ob, khim,
33 no.5:1661-1666 My 163. (MIRA 16:6)
1. Moskmkiy institut tonkoy khimichaskay takhnologii imeni
Lomanosova
~Morpholins) (Propanol) (Eaters)

CBERKASOVA, Te.H.; YERKOMAISHVILI, G.S.
Secondary amino alcohols and their esters. Zhur.ob.khim. 33
no.7:2106-2109 J1 163. (MIRA 1618)
1.,Moskovskiy institut tonkoy khimicheskoy tekhnologii imeni
Lomonosova.
(Alcohols) (Esters)

CHERKASOVA, Ye.M.; BAIANDIN, A.A., akademik
Structure and anesthetic action of aminocarbinol esters. Dokl. AN SSSR
154 no.6t1409-1411 F 164. (MIRA 17:2)
1. Moskovskiy institut tonkoy khimichaskoy tckhnologii im. 14.V.Lomonosova.

GJIT~r "OV
KRINDACH, N.I.; SILIN-BEKCHURIN, I.A.: TUMTSKIT, L.N.-, 'I
High-frequency discharge In a nenn-helium lavey. Zh%r, tekh. fizz.
35 no,9*.1678-1684 S 165. (MTFLA 1800)
1. Fizicheskiy institut Imeni P.N.Lebodeva AN SASR? Moskva,

VEYNEROV, I.B., prof.; KRIJCHkKOVA, F.A., kand. biol. nauk, GIIERKASSKAYA, Ye.l.
Vitamin metabolism and excretion of 17-ketooteroids in cutaneous
tuberculosis treated with tubazid. Vest. derm. i ven, no.13
22-28 165, (MITA MIC)
1. KlIn4ka tuberk-uleza kozhi Ukrainskogo nauchic-saledc,,ra,el'..
- I
skoeo instituta tuberkuleza i grudnoy khirurg'LJ !meni Ynovskogo
(dir.- dotsent A.S. Mamolat), Kiyev.

CHERXASOVA, Ye.Y.
- *~r-
Effect on phagocytosio of the addition of zinc chloride solutions to
the blood. Trudy Vaes. ob-va fiziol., biokbim. i farm. 3:100-102
156 (MLRA 10:4)
1. Yafedra fiziologii Tarkmenskogo meditsinakago inatituta;
zaveduyushchiy kafedroy professor A.I. Venchikov.
(FRAGOCYTOSIS) (ZINC CHLORIDE)

V. /H
L of a change of tine content in. the environment on
~the intensity of heat exchange in frup. P. V. Cherkasova
(Turkincit Med. Inst', A0ikIjuIj:id). , \1 -
S.R. 42, 413-17(1956).-Frogs kept 1 fir, in aq. solti. i)f
O,M3 mg~ ~:,~ YuCII shmv tut incieasc. ill Item exchalige with ~14
-tile vilvirolimelit;' its Illilm cimell. zilct, the Ilval vwha
is InIvered. Ilitri. , - L F
a-C i)f Ilvat euinmr, also taken-, plac after
wbeul'illeolls injection uf strydittlur, ititraic or by immersion -
ill such a.soln. d.ter cbsure of the urinary duct,.

USSR/General BioloLy - Indiviati-.1 DBvelopment. 'Postembryonal B
Develo.nw=nt.
Abs Jour Ref Zhur Biol., No 6, 1959, 23618
Author Cherkasova, Ye.V.
Inst
Title The Reaction of a Growing organ-ism to the Introduction
of Zinc Into It.
Orig Pub Zdravookhr. Turkmenistan&, 195T, No 2, 19-22
Abstract Experiments were conduct-d on chicks beginning with the
2nd day of life and ending with compilete sexual mturity.
In giving chicks and chickens solutions of zinc chloride
of 0.003, 0.125, 5,200 and 1000 mg%, a decrease of
wieght vas observed in the beginni-ng, and later its sta-
ble increase by 6.9-9.7% more than in the control. In
a dose of 0.003 mg%, an earlier development of secondary
sexual signs was noted. The ability of experimental
chickens to lay eggs did not differ from that of the
Card 1/2

USSR/General Biology - Individual Development. Postembryonal B
Development.
Abs Jour : Ref Zhur Bio-I., No 6, 1959, 23618
control, but the weight of eggs exceeded by 6-5-06-8%
that of the control. - V.V. Polovtsova
Card 2/2
- 17 -

CHMKASOVA, Ye . V.
CIERKASOVA, Ye. V., Doe kbd Sci -- (diss) "Reaction of the animal
organism to the injection of zinc as a microcell.1'I AshIchabad , 1958. 19 PP
(Tashkent Med Inst). --list of author's works at end of book (11 titles)
(KLI I)
40-58, 100)

- I -
.pi~vu
C, Effect of boron on gas exchange in silkworms. Izv. AN Turk. SSR
no.3:107-109 158. (MIRA 11:9)
l.Turkmenakiy gosudaratTenny7 meditsinskiy institut.
(silkworms) (Boron In the body)

MKov, A.T.; CHERKASOVA, Ye.V.; KONKIN, A.A.; POKROVSKIY, V.N.
Kfact Vr Sam factors on the formation process of the filament
streams in'%be outflow of viscose. Khim. volok. no.3:32-37 163.
(MIRA 16:7)
1. Vaesoymn" nauchno-insledovatellskly institut iskaostvennogo
volokna (for Serkov, Cherkasova). 2. Moskovskiy tekstillnyy
institut (for Konkin). 3. Vsesoyuznyy nauchno-issiedovateltskiy
Jawtitut steklyanogo volokna (for Pokrovskiy).
(Rayon)

SERKOV, A.T.; CHUMASOVA, Ye.V.
Ways of increasing the BtabLlity of vlazwee fiber foming.
Khim. volok. no.3:40-43 "64. (MIRA 17s8)
1, Voesoyuzrqy nauchno-issledovateliskiy institut iskusstvamogo
volokna.

SFRKOV, A.T.;---qHq~KASOVA, Ye.V.; KOTOMINA, 1.N.
Some causes of filament,, brenkage during the forwition of
viscose fibers. KhIm. volok. no.4:3~-37 165. (KRA 19-8)
1. Vsesoyuznyy nauchno-issledovatellskiy institut iskusstvennogo
volokna.

SERROV. A.T.; CHERRASOVA, Ye.v.
---
Stability in the formation of visco3e fibers on spipmerets with
various diameter orifices. Khi-=. volok. no.6:35-36 165.
(MIRA 18:12)
1. Vsesoytiznyy nauchno-issledovatellsk-iy institut iskusstvennogo
volokna. Submitted January 28,, 1965.

CHIRKASS, Ta.
Mobilizing potentialities for increased production. Prom.koop. 14
no.4:9 AP 160. (MIRA 13:6)
1. Bakratarl partorganizataii arteli im. 30 let USSR, KharIkov.
01harkov-01othing industry)

CHERYULSKAYA A.R.- PERELIMUTER, YO.A.; TOKMEVA, R.O.
Pneumoencephalographic studies in organic psychoses in
childhood and adolescence. Zhur. nevr. i psikb. 64 no.?:
1070-1073 '64. (MIRA 17:12)
1. Kafedra psikhiatrii (zaveduyushchiy - prof. L.A. MirelIzon)
Odesskogo meditsinskogo in3tituta i Odesskaya oblastnaya psikbo-
nevrologicheskaya bollnitsa (glavnyy vrach F.K. Filyanovskiy).

C. iE-
A
~. i.-Y ) A. Ya.
Cherkasskaya, A. Ya. "On t.1-e problem of ruspirator3, constriction of ILt milocles,"
Trudy Kuybyshevsk. vos. med. in-ta, Vol. 1, 1940', p. 22'1-36
I U
,-,'~O: U-2888, Letopi5 Zhurnallnykh Statey, No. 1, 1949.

CHEREAWKItYA, A-Ya.
- I
0,
Structwe of respiratory impulse according to data on mmscular con-
traction of the extremity. ?izlo-l. zh. SHE 38 no.6:702-707 Nov-Doe
1952. (CIML 23:4)
1. Department of Normal Pbysiology of ftybyshev Medical Ingtitute,

ZASHKVARA, V.G.; SENICHENKOp S.Ye.; CHFRKASSYAYA9 E.I.; SEMISALOVA, V.N.
Effect of the size of the grain and of thq sieve c6mpcVeition of
coals on the coking process. Koks i khim. no.8:3-8 162. '
(MIRA 17:2)
1. Ukrainskiy uglakhimicheskiy institut.

vi~
5.
-%6
4cordi.;
J3:,KIucts1Adctd. poteutiolattricatlysic
The r0cAin
toNj(jmxn oK3 Stepanowa, Tekh. By-tit. Glmm Upraric",
I*Jakna (1037)] ,nd. from the curves obtaiQcd~
detd. dl-~
OIL. wnt. 6! xanthate. sulfide.und trithlocarborateft
ructly. With 11, the deiree o1 xituthation 6 detd.!*dometr -
it
into the -,-no. (the no. of NaCW MPj
cally and ixinver Led
IM glucose groups). The potentiornetzic. and i0dometric
values tLat agme well. Thtreutiouallwith'
methods give
CS. in alk. soln. is studied bydctg. the depender,cion time and
teu., a temp. 0 roducts an xanthation, the influence
d1sulfide vrith Sodiiij "no on If the reaction p.
L"TM.Ede.
PM Y eM2!h.! A. of the ratio of 1. CF6: NaOH an the velocity of the xanthation
B Pal-shver and V
A KBIM- Paserjorj4h. &I.-rMular- of Im-ithratiosof 1:1-5. 1:4:4,and 1:12:12atOaud 40%
j4,J5 i~e ity of the forma- -
f 22&' "' The X&DthRtIDU the c1lect of the N,'aOH conca. on the veloc
0 .91IMP16 wbohYdrates and (if cellulose. Ibid. 43D-43.-To tion (if the I xanthate, of NaiS, and of NaiCSs at 40% and
9 ,M . M. by detg. the kinetic data of the- xcuithation of I at 20, 30.
so It information on the kinetics of the xanthation rL~
action a study is made of the xanthation of simp3e rnulti- and 40*. The results,'given 'ia tables, indicate that the,
valent a1cs. such as sucrose. (1) and a degraded- hydrate xanthation occurs according to the equation: ROH +
1). M + CS2
Cellulose (U) with a degree of polymerization of 82, which is NaOR - ROH.,Naoli (11 ROCSSNa +
prepd, by ucid hydrolysis of viscose rayon and is completely H;-D. The no of reacted OH groups/glucose group is uu-
.12Lina alkali. The reAction; are carried out in knowit. For low degrees of esteriftcation the following equa-
scaled tubes.
tion is valid for the reaction velocity.- w Front
there-,ultsof the xanthation of`1 and 11, n (the no. of reacted.
OH groups) is found to be abuut 2. 'The xanth4tion of the
ieterogeneous condi-
high-triol. cellulose takes place under I
tions and is therefore principally different. Because of dif.
fusion of the CS, in the surrounding medium or into the In-:
'orof the fiber the reaction it permutoid In character or
erl
t
the talces place on the surface. Since the reaction is carried
out in sealed tubts it has a tritch more pronounced pertnu- 1
toi&cbaracter and is, therefore:. conWered to be a pseutio-
action and the following equation is used f its-
rnonorriol. re or'
kinetic calcu!~.., k, - 2.3/1 X log 1/1 - x, in which x is the
amt. of combiii~A C%. This equation gives satisfactory
values un to _-5-00,
a dvgt~-e
qge

- -------------
idrnple sugars 2 independent reactions take place: the reac-
lion of C,% with the carbohydrate and wfi;b excess NaOH.
I it the Ist case the velocity of the formRtiois of thexantbate
passes through a max. iiecause the equil, Is continuously
actions. An nr-rcac iR alkali conen. de-
disturbed by side re, i
creases the reacilon velocity in the iKanthEi,tion of I, either-
Lecause 01-1'groups are blocked by NaOIT. or because the
zquit. is shifted to the formation of NaIS and NaICS:. The
Nantbation of alkali cellulose in a heterol;cneous medium
cin lieupressed by.an equation of the Ist ol,deras a pseudo-
uriinial. reaction. Although the reaction should ptoceed
triore slowly because 9f tile beterogencous; conditions the
velocity, in this,case, if winewhat greater Own in a hoino-
g(meous rewtion becituge, in the latttr, there is a consider-
ablY larger vxcess of NaGH present. As laimpared with I,
tLe process i, much slower, particularly on the basis of equal
aints. of reagents. By increasing the temp. the main reac-
tion as well as the side reactions cin be acix-leratcd, and, in
-what
tilt cast of 1. tht velocity of tilt main reactioll is sm"t
gr!!ater thrin that of the side reactions. The retarding cf-
feet of the alkali and of the hetcrogeneoui course of the
reaction are chown in a decrease in the temp. coeff.
R. Brawls

P. IT. A. '3-.
2. USSR (600)
4. Sodium Hydroxide
7. Reaction of carbon disulfide with sodim hydro%ide. 212ur. or-'kl. khjm. 26, '11c. 11
1953.
CS2reacts with NaOH in two consecutive steps. The rate constants for the
two reactions were detd.as well as the relation between the reaction rate and the
conen of the reactants. The energy of activation was also detd.
2:57T36
9. Monthly List of Russian Accessions, Library of Congress, May -1953, Unclassified.