SCIENTIFIC ABSTRACT PAVLATH, A. - PAVLENKO, A. S.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001239520009-0
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: June 15, 2000
• Sequence Number: 9
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

V W ,trvitc-pcv~sO 146 ti kj'. i
RO in -,%Kknl- portions,'and'%
e =t with N.
krid distd.~rxve p-FCJT4cy(olT).4
f e b,~,,

oandill

1,c

1-n .1 . / I " - 'f f
V C- rl F ,
Distr: 4F2cQ
/ Sypthesis of org&Aorine compountill- X11,
ficilt, of fluorobectems., - G IVEY 14111. 1-
lciiltiarpi~~ . ~ff
-11imptlan Aiiid:&i..*budifji*Kt).--Aiia'"Chi~i.-'-,47;id.-.3i~s.
jimpit. 7. 431-42(lMbXin EnglL-,h); cf. C.A. 50, 11201a;
52, 5=i.-PhP was ailynted by the following methtitiq and.
the proportim of FC41411C~ burners funned detd. from the
ultravidlet abliorption spectra reasents. % kid. teulp. of
reactim, and % P-' D.. and M=Iers giveni: 'Wr g. IINQ,
(9p. Sr. 1.41)and 128 X. coned. H.504,84.5, - 10% VDA -;
40 s. HjSO#.H3O. 25 s. 8D% HiSDi. and 30 j. NaNO,. 65.
GD-70', 90 S. -; AcOh'%, 71.2. 0', 96, 4, -; TWNO~.
00-2- ~~- 10D. -. -. CCI, + KA, 03S, cooled, 72, 28,
old NO,, - (5.5 s. Irovu 25 g. PhF). rrAxn temp.,
IN; A% vapor. - (4 g. frmn 00 s. Fh?), 1301. -k
9D, 10. Ionic nartkim give kagtly pjiw~mWtn mixed type'
ve % P- am 10-28% C-L~' presumably
t
tDierilembin 9WDo- and 10% m4somers. 1,2,4-
I N I , bo 153-a'. ws3 prepd. in 49% yield front
57S. . t jr. HjSD&J1m0 and 75 x. fuming HNO~ at
-5t0 in .8% yield Irm 101 L. 23-QM(NO~~ in 101
ed 2 ho. at.105-10 in ultraviolet light with
2D g. dry KF, owd the prom= repeated 3 timm and in .124-5"
79.8% Yield, go. 24% l1rorn 4 a. M cooled awl stirred with
9.5 a. NjOs added in onall portlow. I (I g.) added to.
4 g. GD% chmm at 00 wM a g. HjSD&Jf30 and a F. funting'
1111%, the mixt. bmted to 90' 2 bra. and to 130 10 hrs.,
I
1 4. Mid vowed li)," ke y1eMed 35% SY-FC-H-VOI)i
(a), Furdler mitmUm of 5 X. I with 5 NA
.4 alowl I In..
40
~k
Oil 'I 11-lifill): 1110 tj:ltll. CCKJICd, f"Ift.-d '~n jr-C, and 01C PPI.
dlivit in twilso Yielded a Inixt. Cialfg. IV*% 11. 11 is t'xljtV- It)
sive. Cur%u tit the ubsAirlition tjo--tra fit v-, m,-, und I.
.2 r
PCJ14N% Ix-tween 2700-300U A. are given and the uwfluA
of qumit. unalysis by alitsorlition qx-ctra Mir.~unyi, CA.
SO. 7660i) simplifiLd for mixts. of paxwet., i,r mci.
wt. XlU. Deilvatives of 2-fluaroethylurethan. Gvr,r)-,y
lbid.443-9;
cf. C.A. 49, W94i; 52, 3 911.Z:Tfie following 2-fluormlk)j:
ardhans, RNIIC04C)ft~,F. were prcpd. by adding 0.1
mole CICCh(CITINP (1) to 0.2 mule RN119 Cooled in U) in].
FtO, n1lowing file inixt. to stand overnight, 01trin if
n.try, (trying Ole filtrate. anti CMM. tlK~M
crystif. solvent, ui-j)., givem)i ra'-Z-, 61-50,
W,7; o-Afa44R4, -, 74-b-, 701; m~M#W; ~-, ba
171-40. 68.1% p-AfeC4114, -, 59-110", 82.7: J~-FCWI..
hexane, 75% 80.0; t-R.W.W11a, ligroine, 58-9', 83.8;
CIC,,H,, bmine, 64 , COS,, pi-BrC4114, hunne. 94'. 94.0;
p-1C.H., hemne. 111-12" (yellow crystals), 82.3; o-0,
NCGH., 309; EtOH. 690 (yellow crystals), 86.7; m-Or-
NC4116' 30% EtOH, 51-2% 81.1; p-0lNCs11#. 30% EtOll,
(yellim), $8.7; N-1-Amyl-N-methyl, -. - (N 125-
7"), 92.4; (th 118-20"), 86-3;
W, Ht0H. 100',
Ht0H, W.5% 81.4; ft-Pyrid,
-Y-P -Us( -0dorodhYl),
7.; (city). MOH, 1310'. 80.2; N P
- - MAD*), 87.8; N 1-hydroxy-2,2,24ricklaro-
eikyl) (11~, bleco, 0-1. 63.3; R2,24richlvrodh lid n
Sintiltirly prqA. were:
-, 1210. 85.1.
fluorodk.MiureMms. HjO. ilb", 94.2;

SjtMvjkf of orgen;4
.08-9'. f6.4. With estexpae, blocking agents ie.g. diiso-'
propyl fluomphosphate), toxid doseg*id these comp6s. ad-: 10
ministend to anintals produced no toxic symptoms. The
compds. are being tested as growth inhibitors for expti.
cancerous tumors. AV. Decomposition reactions Df do-
rivatimalfluoroacetkuld. Gy6rgyOlLh,Att"Pavlfith,
And SGO B INd. 451-3.-Flummeetatei (1)
with I-ORM"hit fluoroacemlic whose lbol', HIO
soln. is stable. This soln. treated vith chloride of time
~Hofrn, n reaction) decamp. compIttely. 2-Fluoroitbauol
U) Is also completely decompd. on alk. oxidation with
chloridecilime. Siol. effects of I and 11 are -;mI, . XVII.
Pre allm of 2-fluoroethy1mrAne, Oyorgy Olib and
Attila Paylith. Ibid. 461-3.--See Cal. 50, IW42e.
Janet P. ?-m*WO

A4
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Jan of VM4 whb 2 ~Wei 6f N WA
rrodicitkA of Wo PrWunlh the pm
Ab4 be applk-di'to,tte prepti. tj
~Iktc' TWIatter crwpds. 9" t
A mocn1*1 of
to --~506. treat

and
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ond ift4lu mwilbet
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l
twjc- ppM' hydrcd p
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tored offj umd i be
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