SCIENTIFIC ABSTRACT VASILYEV, P.S. - VASILYEV, P.V.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001858910015-3
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: August 31, 2001
• Sequence Number: 15
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

jj7.T1*1S --jh os t !1!--vski F., !V- i I
3ic1'c?1' kwiiknya, P. P. ,
Gyul' b-id,-,m)v:i, 'i .."'.
TKJ,~:: ir the Fieli .:).f TA,o~--trmo.; pnr)
(IEslC3CYV,miyO v oblasti lpktonov I 'Jav)v 1.
19 . Propn-rit-i firm of '-1,1 yvin~rl-,)yrr'- -wir.5
.-,olocul, r ht-s ,1-16 Thrjir
(3-)oobs,hchoni.,!,i 15. Frenar,-AY
mo 1 ekulyarncl~;n -,re sa i ikh '--, z i21--Ieskiye --7 r,
PERICI)ICAL: Izvesti,-m nrmlk .2367TI. 'A.Joleniye
1)59, r). 5,
A2MILCT: "Block polymerization" of vinylpyrrolidone under
of 1,,0 Pn! of flinitrile of a-zoisool.4ic acid, nn-21
*
2
2
in aqueo,is solutions (Refs 3, 5) hpd been investigrted ~A
instit,ite mentionee 'under Itsaociation. In nonneption
the ph,-;aico-c!ho.-.iica1 properties of various proparatLcn~,
polyvinylpyr-rolidone ~PVP) riere investlig;Lted in this wor,:
because these properties care very important for the

Cr,,,rd 1/3 investication of the biologic nctivity of the prenpx:ltionm.
U I -

, n
Investigation in thp Field of Lqctones rn' Dqctams. SOV1.5
Communictktion 15. 'Preptrrtionj of Polyvinylpyrrolidones Hivinn, :)iffrircrit.
,iolcculnr '.iei,-htr. ,i~!rl `~ioir 1re)norties
The T)ror.,:r,,~tions c,~.n be obtained in vr.-riour, .,,.,,yE;-, t,hC-CforP.,
thoy tl,,`.. ) %init slight -inviations fro-, their physico-
che-nicni dh-~rflCtOri.StiC3.. (Table 1 :- phy3iCO-chemical
characteristics of (!~VP) solutions ss produced in v!ixious
nountriss). Tho poly.-Iierization conditions for (:-VP) from
anueoun solutions in the presence of 30 -!") H 202 and with
0.9-0.5 15~3 concentrations of this initiator are su-narized in
f-able 2. The c',lar:%cteristics of salt water solutions of (PVP)
being i~:ad as a rlrismosubstitutc nre shown in table Relative
V .Scority, os-motic pressure, and the molecular weiZht of tile
various preparations -.,,ere deteritned. A comparison of the
characteristics sho,:is that those of (PVP) Pre more 2ffective
than those of the plasmo subs ti tute. 1 .0 H202had to be used
as initiator in order to obt!iin ;i highly effective pol". er.
The ietermination of the nolecular and the
irv.ro3t_-I(-;.,ttion of the poly`-',s-.),)-.-nity of several pr3parations
3howed that the block polymers have a higher degree of
polyd-ispersity than those obtained in solutions. --Ioreover,

InvestiCation in the Field of Lactones and Lictrm 'n., SC-1/52-59-5-20/40
Communiw~ti-n 15. Proparations of ?olyvinylpyrrolidores Eav-Int-, Different
Molecular and Their Physico-chenical Proporties
a method for obtaining biolop-ically active aturile salt water
solutions of the prcparations hR3 been v.,orked out. There are
2 figurco, -~ tp.bles, cm-c-1 2l refcrences, 12 of rhich Pre
flovict.
ASSOCIATIC~i: Institut organic-1,icskc- khimii irq. i,. D. Zelinsko-yo Alcadnm- 4 i
nauk '3SR (Institute of Org-mic Chemistry imcni
13 D.
Zelinskiy of the Lcademy of Sci-mces, USSR)
r
SUBI.,IITTTD: Jill" 1*,?, 1r,457
I
C p..r.d7

VASILIYEV, F.S., prof.; RUDASHFVSKAYAJF M.M.
Influence of carbohydrates on the erythrocytes of the blood stabilized
with natrog (sodium 2,3,4,-trioxglut&ric acid). Probl. ge-ma'.. i
perel. krovi 5 no.3139-43 Mr 160. (MIRA 14:5)
1. Iz TSentrallnogo ordena Lenina institute, gematologii i perelivaniya
krovi (dir. - deystvitelinyy chlen PWN SSSR rof. A.A.Bogdasarov).
(BLOOD-COLLECTION MID PRESERVATION~ ' (GLUTARIC ACID)
(GLUCOSE) (SUCROSE) (ERYTHROCYTES)

"Th-e lliol~i of ProtA-11-Li-Pild,
Ln the
nresented at t-,e, 5til irit i~i,-A:3 fry,
10-16 Ailv ig6l.

VAS1L',YEV, _v drey Dmitriyevich;
's--l- - JApl Stepanovich; GOLIKOV, An
GOIROKFIOV, Nikolay Stepanovich; KRIVONOSOV, Ivan
Vasillyevich; MURAVIYEV, V.M., red., LAVROV, N.I.,
ved. red.
[Technology of interval hydraulic fracturing) TekYmo-
logiia pointervallnogo gidravlicheskogo razryva plastov;
opyt neftianikov Tatarli). MoBkva, Izd-vo "Nedra,"
1964. 131 p. (MIRA 17:6)

SIJ-,,ONOV, P.M.; KROPANEV, A.I.; TIUNOV, V.Ye.; YASIL YEVIJ.T.;
TURTSEVA., I.M.; SAULDIVA, Ye.D.; DYLDIN, YU.N.;
BRAYLOVSKIY, N.G., 'Lnzh., red.; MEDVEDEVA, MI.A., tekhn.
red.
[Advanced meFthod for car inspection and repair in trains;
experience of the technical inspection point of the Sverd-
lovsk-Sortirovochnaya Station of the Sverdlovsk Railroad)
Peredovoi metod osmotra, i remonta vagonov v poezdakh; opyt
raboty punkta tekhnicheakogo osmotra stantsii Sverdlovsk-
Sortirovochnyi Sverdlovskoi dorogi. Noukva, Transzholdor-
izdat, 1963. 39 P. (MIRA 17:3)

SIVONOV$ P.M.; KITTANEV, A.I.; TIUNOV, V.Ye;; VASILIYEV, P, Tj
TURTSEVA I.M.; SAKALDINA, Ye.D.; YLO V'Y~:'g
BRAYLOVSKIY, N.G., inzh., red.; MEDVEDEVA, H.A., tek-Lri.
red.
(Advanced method for the inspection and repair of cars
in trains] Peredovoi metod osmotra i remonta vagonov v
poezdakh. Moskva, Transzheldorizdat, 1963. 39 p.
(MIRA 16:10)
(Railroads-Cars-Maintenance and repair)

d ) /F S 5- 2 / E'F C - 4
:WCESSM NR., AR5003352 S/0271 /6-4/000/011 /B'016/906
)81.142.2
ISOURM Ref. zh. Avtonia-tika, talemekhanika i vychis-11talinaya tekhnika. 1F
rodnyy tom, Abs. 11B99
UTHOR: Vasil'
~ITL9- Criterion for evaluating the efficiency of di.3crete-in_foniation
t ran amm i ss i o n
~c :1813
SOURCE: Tr. uchebn. in-tov s-~ryazi. M-,ro sv-yazi SSSR, iryp. 20, 1964, 128-139
!TOPIC TAGS- discrete infonnat~()n l.ransmission, discrete information transmission
.efficiency, error correcting oc~kie, c de
f
!TRANSLATION: A formula is devqloped for ev,~Lluating the efficiency E of discrete-
information systems. Vhen information is trarismitted b-
y binar-y codes and the
the efficiency is
,probabilities of transmissior of 0 and I are equal (x,. . )r-
_VIP. -4-- V1p,___, wh-:nre V 7-rr4 11 -,f ~7-
E - i gF 4- L
correspond to 0 and I before the ap-..'11cation )f red,_r.dancy -_rmd~ngl Vand V
no -ind 7nL :L-13
.are the sa-me quantltir3,9 aft~3r the a-T'Ica",~n -f r-r~,_nJa_nr:t C~7t',InFj
Card 113

ACCESSION NR: AR5003352
Le pt-ob ilitla5 of errors Ln reception of 0 and 1 before the applicatio
it, ab n of
redundancy coding; -p,,.arLd Pn, arE. the same quantities after the application of
redundancy coding. The redundancy coding is equivalent to a greater signal durationi
T, the signal t-int., always hii-her than '.he no--,~!,,e H and t,he ~3pectr,im ,T~d~h bp~~ng F,
ie Fo . ff,,~ Fo,~ , H, F, = ff,,,F,, Cori s jAe rabove., E - Iq P
IThe error correction in a riuaaaga -.,6
vystenis ,rith automatic detection and roquest for rapeolition (ADR-Q). The f1delity-
:Izprovemen~ :r-thod requir,~,s that 2-Pt.pr nach me~3sage, a summatior, check ---e transmitted
whose elements are set up frnm the Tnessace elements accordir--r, to a definite law.
'The same law is used at. the receivIng qta~lori for setting w; a check. from the
ireceived monsage; both check3 are comipared. Tf the oheck3 do %cl, tally, _r, error
signal is sent back, and the transmitting station repeats Uie, ruessage. The
following-, assumptions --are-made. for dettermining the eff icier-,7- of the above
of erroneous reception-of 0 and -1 - are equal P.'W PA,P
itie
od. the probabil S
;_Aheelemewtar corresponding to 0 ard I have equal
__T T' --T -T
tio T- T The errors- are,_&Ustrib-~~ fed-aced-i-ding-tb a _7
-.7 7: 48 - 0 a
bihomialjaw'i~On -the striength~~-of -the -afore-a~Lid - AheWficljf')i is

:ACCESS1011 NR- A-R5003352
Ph +
E- Ig - --.- N.
+ 6-
ir
where p4 1-9 thn prohabillty of ff~li b~ detect errora In a mossago containing b
s the !A11le ttlFi f7nd Of thp la.-t character in a
n t:ic~ next mossaj~~f-, -_9 tho
and n n.,-

L 560 39-65 EV;T(d)/EED-2 Par-4/Pae-2/Pl-4
ACCESSION NR: AR5012182 UR/0372/65/0C1D/003/V0416/VO46
51:621.391
SOURCE: Ref. zh. Kibernettka. Svodnyy tom, Abe. 3VI59
AUTHOR: Vaoil'yevA P. V.
TITLER: A :riterion for eveluating the effectivenes,; of discrete information
transmission systems
CITED SOURCEt Tr. uchebn. in-tov svvazi. M-vo sv-yazi SSSR, ,yp. 20, 1964, 128-
139
TOPIC TACS: discrete information transmission, binary aYTMT--tr1c channel,
r-einqU4r-y transmission, correction er-de
TRA14SLATTOV, -Tbe authr)r r-7oiv~n c-rtain consileratioris and concludes from thege
C n~ lat.~ a ~,iriarv E5ymmetrtc channel can
'hat !,I~- f'r v
characterized by ~rle a-vignitude fI 17J, - pj,
Pjq,4-p1l,r rrt
where po and p,, p and p repres-tit t1he orebabiltt,, of errors in receiving
po p
Card It' 2

L 5602-'~--65
ACCESS1014 NR! AP-5012182
zero and unit signals, r,.spectively, prior to the use of coding and after its
use, whilp Tt arid T Pi '11" !h~- -w4qft'.Idtc for Pertads of elemental
transmissions corrt-sponding tn sl4nais D and 1 prior io and after coding.
pArt 1, it 1 c4qea and
-fficienrv of a Lraris-
an assiRned nuTber o t
10v.
SUB CODF DF,
A Card 2/2

BLOHIN, N.N.~ VASILIYEV. P.V... Rand. biol. nauk; LEDEDIl"SKlY,
A ~ V. , ~ ~-of -,.' .- Ede 21'a-a'sed ; YAZDOVSKIY, V.I., dok-tcr med.
nauk, prof.; CHIRNOV, A.G.; NIKOLAYEV, V..R,., red.
[Man in a apace t3hip. Eighth diucutisJon. Par-ticipant.3 In
the discussion: N.N.Blokhln and others] Chelovek v kosmi-
cheskout korable. Beseda vos?maia. V besede uchastvuiut:
N.N.Blokhin I dr. McAva, Znanie, 1965. 30 P. (Novoe v
zliizni, nauke, teklmike. VIII serlia: Biologiia I medi.-
tsina, no.?) (1-11IRA 18:4)
1. De-fstvitel*rxyy chler~, prezident AWl SSSR (for Blokhin').
2. Deystvitellrjyy chlen AMN bSSR (for Lebedinskiy).

7-010 a 4rCs OF.- ~*_Co 4 0 0 0 0 6 a 0 0 a a W 9
946009*00600000600060 1 0-4.47077 0.0-4 It 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0a I 1 1 4 1 4 ? 0 9 111 11 11 11 IS 16 1) It 10 IQ j It D n .4 15 A ?I N x it 11 U D 1. 1, a is 4; 1., At 0 1~ 0
A 6 1 _11. S I V y -4 1 AA t L,
4
60
00
sot -00
00 The effect of laterformation *ashoula tit toll depoettv .60
on the chemical -technological propetties of the Kliflovskif
06 C692. 11. V. Vaqll'ev. M. G. l'ol.iv an-[ A. V. S"Inti,ev. -00
AisreAs 7, 3-9; Khm. Rifirat. /Axr.
1939, No. 11, W-rhe inimstigation tit it no. of vial
'r Latnples 4lowed that there is a rclation-Jup betwt-rn th
ancit-tit washouts anti the compri., the ceiking prufwfties
and the lictrogruphic chjractvri~tics tit cnals. filter-
fannation washoot,i have a detrimental tffi~ t on thectiking
0 projxr6- W U Iletur
0:
so
00 .00
0
a* 0
Notil
It
W7 00
LL L't 0
ASS-ILI .17, URCICAL LIIIIIIA11,111 CLASUFKATICII 2--
slow SMAJI 12"
Isla.,
If
AT-00 Is , . -1 _. . ,
00 0-8 slit I a I 19 a I III, im a a 3 -1
0 0 so 8
so

VASIL' M F.V.
.
Methods Of studying indeterminate coal-bearing strata as found in
the Kizel coal fields. Trudy Inst.geol.nauk. no.90:53-69 147.
(KLRL 9:11)
(Xizel BaBin--Coal geolog7)

V,'1-SI1T.tYL-V, F.V.
Geology
Faleo geographical conditions in the formation of coal bearinE deposits of the Lower
Carboniferous series of the western slote of' the Urals. Reviewed by C. Ye-Incr.,
Izv. AN SSSR. Ser. geol., no. 1, 1952.
1952
9. Monthl List of Russian Accessions, Library of Congress, May -X" Uncl.

A r i ; - '~ JT- V
i~
-~ J I- T !--, r
ABRAMOV, S.K., kand.tokhri.nnuk, AVIIISHU1. S.G., prof.. doktor tekhn.nauk;
AMMOSOV, I.r., dol-tor ~-,etpl.-min.nauk; AIIDRIYFVSKIY. V.D., lnzh.;
AUTROPOV, A.U., inzl,--..; id*,hlTAS"-rff;, B.L.. inzh.; BM-GMAN, TS.Y.,
inzh.; BLOUA, Ye.lfa., 4-ilzh.; BOGAGHE-7A, Ye.U.. inzh.; BUKRINSKIT,T.A.,
kand.toklin.nauk;.,VA,SIL~Y:-,V, P-V., doktor geol.-min.nauk; VINOGRADOV.
B.G.. inzh.; i.nzh.; GORDIYEIZO, P.D., inzh.; GUSEV, N.I.,
kand.takhn.nauk; DORW:Hl*.N, I.V., kand.geol.-mln.nauk; KAIXYKOV, G.S.,
inzh.; KASATOCHKIN, V.I., doktor khtm.nauk; KCROLEV, I.V., inzh.-,
KOSTLIVTSEV, A.A., irmh.- l2iATKOVSKIY, L.P.. inzhA; KRASHIQUIRlIKOV, G.F.,
prof. doktor geol.-min.ritiuk; KRIKUNOV, L.A.. inzh.'; 1XVIT, D.Ye., inzh.;
LISITSA, I.G., ka rid. toklm.nauk; WSHNIKOV. V.A., inzh.; MATVRYEV, A.K.,
dote., kand.geol.-vilm.nmik; HF-MISHVILI. G.Ye., iznh.; MIRONOV, X.V.,
inzh.; MOLCHANOV, I.I., -.7-nh.; IMUMOVA, S.N., starshiy nauchnvy sotrudnik:
lWIPMkV, V.Ye.. ii,.zh., PAYWY. F.F., doktor tekhn.nauk; FANYUKOV, P.N.,
doktor geol.-min.nax~.k; POPOV, V.S., inzh.: PYITLIN. M.P., kand.tekhn.
nauk; RASHKOVSKIY, Ya.l:., inzh.; ROMANOV. V.A.. prof.. doktor tekhn.
nauk; RYZHOV, P.A., prof., doktor tol-hn.nauk; SELYATITSKIY, G.A.. inzh.;
SPA-RANSKIY. M.A.. irmh.; T1,10,11TIYEV. Ye.V., inzh.; TITOV, N.G.,doktor
khim.nauk; GOKAREV . I.F~, itizh.; TROYANSKIY, S.V., prof., doktor geol.-
min.nauk; FEDOROV, E.D., elots., lmnd.tekhn.nauk;FJMOROV. V.S., inzh.
[deceaned]; KH%fEWOV.'JKJY, A.B., prof., doktor geol.-min.nauk; TROTANOV-
SKIY, S.V., otvetstvennyy red.; TWIGOREV, A.M., red.; KRIKUNOV, L.A.,
red.; KEJZIMrSOV, I.A., red.; KRONOV, K.V., red.; AVERSHIN, S.G., red.;
BURTSEV, M.P red.- VASIL'YET P.V. red.; HOLCHANOV, I.I., red.;
RYZHOV. P.A.:'red.:'B-i ~Off. ~V.-.~, tnzh., red,-, BIA)KH, I.M., kand,
tekhn,nauk, red.; BUKRIIISKIY, V.A., k-and.tekhn.n&ukj red.; VOLKOV. X.Yu.,
inzh., red.; VCRWIYIT. L.A.. inzh., red.; ZVONAREV, K.A., prof. doktor
tekhn.nauk, red. (Continued on next card)

ABRAHOV, (continued"! C1 ~'d "! .
ZDANOVICH. V.G., proAf ,col-tor tokhn.nauk,red.; IVANOV. G.A.. doktor
goole-minanauk, red-- N.M., red.; EUROTEOV, G.Y., ]mnd.geol.-
min.nauk, red.; KCRUTY(A', kand.tekhn.nauk, red.; MAKKAVE-7EV. A.A.,
doktor geol.-min.naij-, OlffLICHMIKO, A.11..ksnd.tekhn.aauk.red.;
SNIMERZON. red.; USHAKOV. I.H., dots.. kand.
tekhn.nauk. red.; Yl--,~IWYOV. V.S.. ~w nd.gnnl.-mtn.nauk, red.: KOROLNVA,
T.I., red.izd-va; Z.I., red.1zd-va; PROZOROVSKAYA, F.L.,
tekhn.red.; NADEINSKAY.4, A.A., tekhn.red.
[Mining; an encyclope~-iL- 1r;,ndbook] Gornoe delo; entaiklopedicheakii
apravochnik~ Gjav~ rvc.~ A,H.Terpigorev, HoBkva, Gousnauchno-tekhns
12d-vo lit-ry po u4,ol~YtiZ fiTOMYS111. Vol.2. [Geology of coal deposits
and surveying] Geol()?-,'4'i! vqolliqkh moutorozhdonil I markaholderskoe
delo. Redkolegiia tor-i- !;.V.Tro1anskiy. 1957. 646 p. (MIRA 11:5)
1e Chlon-korreo ondent 1.1i SSM (for Kerava ev)
Mal 1:( oj (,;:y--Divt ionarjesi

VASILIYEV p _Vagjj!yQ_yjCh; HALININ, Sergey Ivenovich; KOROINVA, T.I.,
~ -~j qtr _,
red.izd-ve; aDVIAR, ;S.Yo., tokhn.red.
Uffect of basic geological factors on the behavior of rocks in
boreholes] V1iianie oanovnykh geologichoskikh faktorov na pove-
denie porod v gornykh vyrabotkakh. Moskva. Goo.nauchno-teklin.
izd-vo lit-ry po gornomu delu, 1960. 92 p. (MIRA 13:3)
(Petrolojw)

UJILlavi I
VASIL'YEV,.-Fetr ___ch; YERSHOVv A.D.9 glavnyy red.; KREYTERp V.M.v
zam, glavnogo red.; KALMYKOV9 G.S.i red; BRITAYEVp M.D., red.;
KRASNIKOV, V.I.v red.; MALYSHEV, I.I.p red.; M0MDZJfIq G.S.v red.;
SAAKYAN# P.S.p red.; SMIRNOVy V.I.p red.; SOLGV'Yr-,Vp D.V.9 red.;
CHFMOSVITOV9 Yu,Lat red.; KHRUSHGHOVg N.A,# red.1 PANOVA, A.I.,
red.izd-va; GUROUp O.A.# tekhn.red.-.
(Coal] Ugoll. Moskvav Gos.nauchn.-tekhn.izd-vo lit-ry po geol.
i okhrane nedrt 1960. 343 p. (OtEsenka mestorozhdenii pri
poiskakh i razvedkakhg no. 5) (MIRA 14:2)
(Mine examination) (Coal)

14ATVEYEV, Aleksandr Kirillovich; VASIL'YET, F.V., doktor geol.-mineral.
nauk. retsenzent; KRAVT3O-V-,A'.-T.-,-a6kio'r deol.-mineral.nouk,
retserizent; IVANOV, G.A., doktor geol.-mineral.nouk, retsenzent;
MIRONOV, K.V., nauchnyy red.; KOROLEVA, T.I., red.izd-va;
KONDRATIYEVA, M.A., tekhn.red.
[Geology of coal basins and deposits in the U.S.S.R.] Geologiia
ugolln.vkh basseinov i mestorozhdenii SSSR. Moskva, Gos.nauchno-
tekhn.izd-vo lit-ry po gornormi delu, 1960. 495 p. (MIRA 13:11)
(Coal geology)

CHERNOUSOV, Yakov Mikhaylovich; RSIL!M, P --red.; IZRAILEVA, G.A.,
,,V -,
red. izd-va; GUROVA, O.A., tekhn. red.
(Course in the general geology of coal deposits]Kurs obahchei
geologii ugolinykh mestorozhdenii. Moskva., Goageoltekhizdat
1962. 294 P. (MIRA 16:11
(Coal geology)

VASILIYEV., P.V., doktor geologo-mineralogicheskikh nauk
Using geological observations in determining physiocomechanical
properties of rocks. Mauch, soob. IGD M67-71 163.
(KIRA 16 : 10)
(Rocks-Testing) (Geology,, Stratigraphic)

VASILI-YRY,.;P.V. (Leningrad)
Effect of an increased and decreased oxygen content of inspired air
on animals with cerebral anemia. Arkh.pat. 18 no.5:87-89 156.
(HLRA 9:12)
le Iz kafedry patologicheskoy fisiologii (nachalinik -; chlen -
korrespondent AHN SSGR prof. I.R.Patrov) Voyenno-maditainskoy ordena
TAnina akademit iment S*M*Kirovae
(ANEMIA, experisontal,
cer8bralj-:*ff. of oxygen content in Inspired air (Rua))
(OXYGIIN, effects,
on exper. cerebral anemia (Rue))

CA Sec.2 V61.9132 PkWsidlogy.eta. Doc 56
5551. VASILEV P. V. Chair of Pathol. Physiol., Military Med, Acad., lAningrad.
*Possibilities of development of neck-brain collateral
circulation in mammals (Russian text) FIZIOL.Z. 1056, 42/5
(376-382) Tables I Blue. 2
The development of collateral circulation after successive ligation of carotid and
vertebral arteries at different time Intervals waB beat in dogs, and decreased In
the following order: eats. rabbits, white rate and white mice, The general beha-
viour of the animals, pain sensitivity, pupil reflex. body temperature-. respiration
and mortality served as criteria. In dogs, simultaneous ligation of both common
carotid arteries and 2 vertebral arteries did not produce signs of acute cerebral
ischaemia, while in mice, ligation of the second carotid artery 13 to 42 days after
ligation of the first one produced nearly 100,79 mortality. It is concluded that the
potential development of collateral circulation improves with the development of
the CNS.
Simonson - Minneapolis. Minn.

VASILOYEV, P.V., SAKSONOV. P.-P.
- 1-1:11:1 Chnractpristic3 cf aninal renctions to drugs in rndistion injuries,
Farm. i tok-B. 21 no.3:30-33 KY-Je 158 (MIRA 11:7)
(COBALT, -"J"dionctive,
renction of Irradinted nnimals to vnrious drugs (Has))
PRUGS, effects#
same (Rua))

USSR/Pilar;-mcoloc-y and Toxicolory Miscellaneous Preparatiins V
Abs Jour Ref Zliur - Diol., Vo 2, 1959; 92e9
Author Vasil'yav; P.V., Sa ~Is Onov, P.P.
List
Title Pharmacolor,-j of Pyr-)[~eiiic Bacterial PDlysaccharides
Orik; Pub Byul. eksperi!A. b131. i med., 1957, 44~ N-, 10, 77-80
Abstract The preparation of pyra'r-,e--~ic p,)lysaccharlde (PP) obtai-
ned frou the cuilture of Pr3teus vul(,arft is .catoxic aud
has :io local irritating effect. PP ad;ri-,nistered tr, rats,
rabbits and doCs in d-)ses of 1-2 r~ /k~'- pr:jduces L~radual
rise Df te-uperature (durinr -~--2-1 houm). Tilereafter,
~ 12 ;_~
the body teriperature decreases -and returns to t*.e i:.itial
level In 5-7 hours. Prelirdnary aftUt.istration )f n'Dv-)-
cain and uretha~ie decreases this effef:t. PP has a-,lti-
inflwmtDry action. When PP is intriduced in a d)se -)f
500 )) /kg, a short-lived hypoteusion and respiratory do-
pressi,):-. is observed. -- A.M. Iva-.Ii';skiy
Card 1/1

BSJAYp VoYes; VASIL'YEV.9 P.V,; SAKSONOV.,P.P.
Data on the comparative pharmacological characteristics of various
salts of merca-min 'Farm, i t*.B, 23 no. 5:450--455 S-0 160.
(MIM 13:12)
(ETHYLAMINE)

VASIL'YEV, P.V.; SAKS.011OV) P.P. (Moskva)
Pharmacology of various high-molecular polysaccharides. Biu.1.
ekap.biol.i mad. 50 no.9:97-100 S 160. (Wl-A 13:11)
(POLYSACCHAIdDES)

BELAY, V.Ye.;_-!ASIRYEY,-jF.V.; SAKSONOV, P.P.; CIMUMIKO, G.T.
Reactivity of the organirm to durgs in radiation sickness.
Med.rad. no.11*72--78 161. (mm 3-4: 1-1)
(RADIATIDII SICKIMS)

M
VASMYEV, P. V., VOSKIESENSKIY, A. D. and GAZENKO, 0. G.
"Some Problems of Experimental Space Physiology1f
report presented at the 13th Intl. Astronautical Federation Congress (IAF)
Varna, Bulgaria, 23-29 Sep 1962

VORYNKIN, Yu.M.; YAZDOVSKIY, V.I.; A.M.; VASILIv.hv, P.V.;
GYURDMIAN, A.A.; GUAC-vSKIY, GORBOV, F.D.; SMYAPI71-1
A.D.; BMAY, V.Te.; BAYEWSM, RX.; AMMMOV, G.V.;
KORUTEV) V.I.; KASIYAN, I.I.; YEGORGV, A.D.; SILIVESTROV,
M.M.; SIETUHA, S.F.; TEREMIYEV, V.G.; KRYLOV, Yu.V.; F014111,
A.G.; USHAKOV, A.S.; DEGTYAREV, V.A.; VOLOVICH, V.G.;
STEPANTSOV, V.I.; PYASNIKOV, V.I.; YAZDOVSh'IY, V.I.; YASHIN,
P.S., tekhn. red.
(First opace flights of man; the scientific results of the
redicobiological research conducted during the orbital
flights of the spaceships "Vostok" and "Vostok-211jPervye
kosmicheskie polety cheloveka; nauchny remlltaty mediko-
biologicheskikh issledovan-*Li, provedemykh vo -n-oria orbi-
tallnykh poletov lcorrablei-sputnikov "Vostok" i "Vostok-2.11
Poskva, I7~d-vo Akad. nauk SSSR, 1962. 202 - (MIRA 15;11)
(smm mmacriE) (swicz FLiGHT aitAINIVG~

ACCESSION NR: AT4042642 S/0000/63/000/000/0006/0008
'AUTHOR: Akulinichev, I. T.; Bayevskiy, R. M.; Belay, V. Ye. Y-asillyev,
Gazenko, 0. G.. Kakurin, L. I., Kotovskaya, A. R.; Maksimov, D.
G.; Mikhaylovskiy, G. P.; Yazdovskiy, V. 1.
TITLE: Results of physiological investigations aboard the "Vostok-3" and
"Vostok-4" spaceships
SOURCE: Konferentsiya po aviatsionnoy i kosmicheskoy meditsine, 1063.
Aviatsionnaya i kosmicheskaya meditsina (Aviation and space medicine);
materialy* konferentsii. Moscow, 1963, 6-8
TOPIC TAGS: biomedical monitoring, electrooculogram, pneumogram/Vostok-3,
Vostok-40 EEG, EKG
ABSTRACT: A number of physiological indices were monitored during the
tandem spaceflights of Nikolayev and Popovich (Vostok-3 and Vostok-4). New
procedures used for the first time on these flights and improvements of e3dat-
ing equipment yielded a great deal of physiological information. Weightless-
1/5

ACCESSION NR: AT4042642
ness had no noticeable effect on the functional state of the CNS in either cos-
monaut, as evaluated on the basis of performance of various tasks. EEG's
showed a dominance of comparatively high-amplitude rhythms with a frequency.
of 5 to 7 cps, similar to those observed in athletes after intense physical
exertion, during the first hours of weightlessness. Later a gradual shift
toward beta-rhythms with a reduced mean amplitude of EEG biopotentials
occurred. Heightened emotional stress in the first hours of flight and before
reentry was reflected in decreased electrical resistance of the cortex.
Functional stability of the higher involuntary nervous centers is indicated by
the maintenance of normal daily variation of cortical resistance --higher at
night, lower during the daytime--during the rest of the flights. EOG's
(electrooculograms) were used as an index of the functional state of the
vestibular apparatus. Asymmetries in oculomotor reaction, which could have
indicated disturbances of the vestibular centers'. were not observed in either
cosmonaut. Vestibular tests not supplemented by EOG's also failed to yield
any evidence of vestibular disturbance. Oculomotor activity was also used
as an index of general and motor activity. Variations in oculomotor activity
had, a phase character. At the beginning of the flight Nikolayev, and to
Card 2/5

ACCESSION NR: AT4042642
a lesser degree Popovich, showed an increase of oculomotor activity up to 4
to 6 eye movements per second. Eye movements of an uncoordinated character,
of both large and small amplitude, were recorded. On the 6th and 7th orbits
eye movement fell off, and later EOG's show periodic increases and decreases
in oculomotor activity. Toward the end of the flight a second stable increase
in oculomotor activity occurred, but its level was lower than at the beginning
of the fligat, Cardiac activity was monitored by EKG's (using chestleads).
Increased pulse rates (from 98 to 112 for Nikolayev, and from 94 to 136 for
Popovich) occurred immediately before launch, with corresponding shortening
of the PQ and QT intervals, EKG changes during the powered-flight phase
were similar to those observed in ground experiments with centrifuging. The
maximum pulse rate during the first minute of flight was 136 for Nikolayev and
132 for Popovich. Normalization of pulse rates to the rates observed 4 hr
before launch took place on Nikolayev's 6th and 7th orbit and on Popovich's
3rd to 4th orbit. Normalization of pulse to initial rates took 5 to 10 min dur-
tests, No IKG changes indicating disturbances of automatism, excitability, or
conductivity were observed. In flight Popovich registered 3 separate extra

ACCESSION NR: AT4042642
systoles; this had also occurred during training tests. The character of daily
variation of cardiac activity remained unchanged. Pneumographic data revealed
no respiratory irregularities. Some increase in respiration rate was noted
during the powered-flight phase; this had also been observed during centrifuge
tests. No pathological change in physiological functions of either cosmonaut
was observed during flight. During the powered-flight phase, functional shifts
similar to those observed during centrifuge tests occurred. Definite changes
in the functional state of various physiological systems took place during the
first hours of orbital flight, as indicated by the inhibition of pulse-rate norm-
alization and the character of EEG and cortical resistance changes. Changes
in the' character of EEG's during prolonged (3 to 4 days) weightlessnes in-
dicate shifts in the interaction of excitation -inhibition processes in the higher
levels of the CNS. However, the mental activity and neuro -regulatory
functions of the cosmonauts remained at a high level.
ASSOCIATION: none
Cd?d 4 5

ACCESSION NR: AT4042642
SUBMITTED: 27Sep63
NO REF SOV: 000
Card -5/5
ENCL: 00 SUB CODE: 00
OTHER: 000
V
_ffij,?

A6CESSION NR: AT4042662
s/oooo/63/ooo/ooo/0096/0101
AUTHOR: Vasillyev, P. V.; Belay, V. Ye.
TITLE: Effect of drugs on reoietance to acceleration strena
SOURCE: KonforentGiya po aviatolor y i koomicheakoy meditaine, 1963-
Aviatsionnaya i kosmicheskaya meditsina (Aviation and apace medicine); materialy'
konferentaii, Moscow, 1963, 96-101 -
TOPIC TAGS: acceleration, rabbit, mou6e, adrenalin, antiacceleration drug,
phenamine, ephedrine, chloral hydrate,,pentothal, dog, rat, pharmncological agent
ABSTRACT: The effects of adrenalin, noradrenalin, phenamine, phenatine, ephed-
rine, chlora.1 hydrate, and pentothal were teL;ted on white nice, rats, rabbits,
and dogs for the purpose of determining whether thcGe substances can increase
the resistance of animals to accelerations. Solutions of these substances were
adminiatored intraperitoneally in mice and rats and intravenously, subcutaneously,
or intramuscularly in rabbits and dogs. Experiments with adrenalin and no-
adrenalin on both rabbits and mice gave contradictory and indefinite results.
Experiments with phenamine gave poeitive results. When doses of phenamine ranging
Card 1/2

ACCESSION NR: AT4o42662
from 0.8 to 1 mg/kg were administered intraperitoneally 15--30 minuten before the
animals were subjected to accelerations of 50-556, th6 rcsiatnnce of the animals
to effects of accelerations (based on Lr~o) increaced by 8.7 g as compared with
the controls. If phenamine was administered in doses of 1-3 mg/kg, the positive
effect of phenamine was lowered, and when doses of 5 mg/kg were administered, a
negative result was observed. Sa.tisfactory results were obtained with ephedrine.
Best results with ephedrine were obtained when donna of 0.5 mg/kg were used. If
the dosage was cut in half, ephedrine woo ineffe 'ctive, whereas if the dosage was
increased, it lowered the positive effect of.the drug,. Further experiments
with adrenalin are being performed using rabbits and administering the drug intra-
muscularly. Experiments with narcotics (chloral hydrate and pentothal) gave
rather indefinite results, Analysis of data obtained in the experiments indicates
that by using pharmaceutical agents to change the functional condition it is pos-
sible to increase the resistance of the organism to tho effects of acceleration.
ASSOCIATION: none
SUBMITTED: 27SeP63 ENCL: 00 SUB CODE: L6
NO REF SOV: 000 OTRER: 000
Card 2/2

S/226/63/000/cOl/002/0-04
Ao66/A126
AUTHORS: Vasil'yev, P.V., Voskresenskiy, A.D., Gazenko, O.G.
TITLE: Experimental studies in space physiology
PERIODICAL: Akademiya nauk SSSR. Izvestiya. Seriya biologicheskaya, no. 1,
1963, 15 - 23
TEXT: The accumulation of data relating to the physiological effects of
space traveling upon the human organism makes it necessary to consider the two
alternatives of experimental research: 1) the study of Individual functions
(heart activity, respiration, etc.) under the influence of certain factors of
actual space flight; 2) the study of the physiological effects of certain fac-
tors of space flight. The second alternative involves comprehensive animal ex-
periments which, though only indicative of the relevant reactions of the human
organism, make it possible to work out diagnostic criteria and training programs.
The necessity of experimental research into the physiological mechanisms is il-
lustrated by the effects of transverse acceleration. Data relative to pulmonary
circulation, oxygen consumption by the cardiac muscle, oxygen tension in the
Card 1/2

S/216/63/ooo/c,ol/002/004
Experimental studies in space physiology Ao66/A126
cerebral tissues, and the functions of the central nervous system, an well as
literature data were used to set up a diagram illustrating the principal physi-
ological effects of transverse acceleration which are as follows: 1) Changes
in pulmonary ventilation and in the redistribution of blood in the lungs disturb
the oxygenation of blood in the lungs; 2) redistribution of blood in the vas-
cular system of the cerebrum, accompanied by a higher intensity of the afferent
impulses, disturbs nutrition and the regulatory activity of the brain; 3) gen-
eral changes of the hemodynamic conditions de 'teriorate the supply Of 02 to the
heart. These pathological symptoms were observed exclusively in transverse ac-
celerations lasting longer than 1 min. It appears possible to describe physiol-
ogical changes quantitatively and to set up a model reproducing physiological
changes in the human organism under various conditions of space traveling. Such
a model will permit an estimate and prognosis of the astronautts state of health.
In addition, better training programs may thus be worked out, and also the ac-
tion of pharmacological and other agents can be examined under conditions of
space flight.
SUBMITTED: August 24, 1962
Card 2/2

r
SAKSONOV, P.P., pAlo;.-.Ak ,rad Ito iris 'Koy iluziby; VA;411.~-IYIEV, 1'.V.; polkovnik I
mfllditsin,fl~oy ,iluzhby; 141-1AY, V.VO., j-.,r)dj-,clkovnJ.k aieditsinskoy aluzhby; ,
ME'RIENKO, G.T., rk,"i its' r.':3k'-,7 sl%zhhy
Characteri3tLcs of Oin, action of drullm in ar-ato rLtdiation
sickness; a review of the literature. Voon. - med. .zhur. no,.l:
44-50 1963. (MIHA 17- B)

BELAY, V.Ye.;. U~ILlY1,1, ROLCHIN, S.P. (Mro3P.711)
Reactivity of '-! a anizal br;,d7 to narcritics frllc,.ring a prc-
-lonRed effect of lateral acrelcration. Farm. I toks. 26 no-5--
559-563 S-0 163. (MIRA .17s8)

PABU41) V. V.; ViV)ILIYFN, P. V.; BELAY, V. Ye.
'I Reactivity in space medicine."
report presented at the 15th Intl Astronautical Cong, Warsaw, 7-10 Sep 64.

PARIN, V. V.; VASILIYEV,-P. V.; BELAY, N. Ye.
"Some problems of reactivity in cosmic medicine."
report submitted for 15th Intl Astronautical Cong, Warsaw, 7-12 Sep 64.

1 41619-65
ACCESSION NIP: A 0 906
tration of the
TTED: l9Aug64 Au
SUBMI VUB COM-
NO REF SOV: 002 008
2/2

89-66"Exroi-YArs
ACC NR- AR6005244 SOURCE CODz',: UR/ 07'.
AUT$OR: Vasillyev, P. V..-
TITLE: Concerning the question of the effi ciency of system a for u--ta transmission
using a feedback channel
SOURCE: Ref. zh. Fizika, Abs. 9Zh8O
REF. SOURCE: Tr. Nauchno-tekhn. konferentsii Leningr. elektrotekhn. in-ta,,Avyazi,
vyp. 3, 1964, 27-30
TOPIC TAGS: data transmission, signal distortion, communication channel
ABSTRACT: An expression is obtained for determining the efficiency of systems for the
transmission of discrete information with a feedback channel, with account taken of
the distortions in the channel.
SUB CODE: 17

ACCESSION MR: AT4037702 S/2865/64/003/000/0318/03n
AUTHOR: Belay, V. Ye.; Vasil,yev, P. V.; Kolchin, S. P.
TITLE: Effect of prolonged transverse acceleration on the functional state of the
central nervoua 6yetem in animals
SOURCE: AN SSSR. Otdeleniye biologicbeekikh nauk. Problemy* kosmicheskoy biologii,
v. 3, 1964, 318-323
TOPIC TAGS: acceleration, centrifuge, mouse, rat,central nervous system, chloral
hydrate, narcosis, sodium pentothal, conditioned reflex
ABSTRACT: The functional state of excitation-inhibition processes in the cerebral I
cortex and subcortical structures under the effect of transverse accelerations of i
various magnitudes and durations was studied in 467 mice and 80 rats. The
functional state was estimated on the basin of response to two narcotics, the firsts
(chloral hydrate) acting primarily:on the cortex and the second (sodium pentothal) 1-7-
on the subcortical structures. Acceleration was generated on a centrifuge with
a radius of 3-7 m. The usual direction of acceleration was back-to-chesto The
general condition and behavior of the -1--1s depended an the magnitude and dura-
T

ACCESSION NR: AT403M
tion of loading. Acceleration of 13 g for 9 min produced depression, quiescence,
and tremor, while the same acceleration for 3 min produced general excitation ex-
re as 'in increased motor activity and aggressiveness. Reaction to the drugs
ed
also varied with the magnitude and duration of acceleration. The duration of
chloral hydrate narcosis in mice subjected to 13 g for 3 min was half that observed
in the controls; the same acceleration for 9 min caused narcosis to last more tMA'
twice as long as it did in the controlo. Analogous results were obtained with
rate, though the differences between centrifuged animals and controls were less
-pronounced. Testa with sodium pentothal produced exactly opposite results. Ac-
celeration of 13 g for 3 min increased the duration of sodium pentothal narcosis,
while 9 min of the same acceleration decreased it. Testa conducted to determine
the time required after centrifugation for excitation-inhibition processes to re-,~
turn to normal showed that chloral hydrate narcosis of close to normal duration
can be obtained only when the drug is administered at least 2 hr after contrifuga-,
tion. This may be compared with a normalization time of 10 to 15 min for condition-
ed reflexes. It in concluded that longer (9 min) accelerations result in iahibi-
tion of the cortex and excitation of subcort:~cal structures, while the briefer
A I
Car,:C, 2/3

Acczssim NR: AT4037702
(3 mialf accelerations excite the cortex and inhibit the aubcortical structureso
ASSOCIATION: none
SUBHI=: 00
No Ra sov: 008
MCL: 00
OTM: 003
SUB CODE% PH# LS,
Card

- 1112 1
BELAY, V.Ye.; VA61LIYEV, P.V.; KOLCHIN, 5.F., MAUYAM.NKO, S.V, )
Effect of str7cbnine on Lhe re5ist-qnce of ani=aln -10 a-
Fat. fiziol. i eksp. terap. 8 no.5il5-20 S-0 '64.
(MIRA 18:32)
1. Submitt,-.d May 28, 1963.

-VASIL"YEV, P.V.; GERD, M.A. (Moskva)
Effect of acceleration on the higher nervous activity of dogs.
Pat. fiziol. i eksp. terap. 8 no.6:3-7 11-D 164.
(mim 18:6)

VOLYNKIN, Yu.1-T.; ARUTYU100Y, G.A.; ANTIPOV, V.V.; ALTUKHMV, G-V-;
BAYEVSKIY, R.Y.; BEUY, V.Ye.; tZYANOV, F.V.; BRYMIOV, I.I.;
VASIL rY-EV, , 'P.V.; VOLOVICH, V.G.; GAGARB:, Yu.A.; GELIL, A.M.;
GOIWOV, F.D.; GORSHKOV, A.I.; GUROVSKIY, N.N.; YESHANOV, N.Kh.;
YEGOHOV, A.D.; KARPOV, Ye.A.1- KOVALEV, V.V.; KOLOSOV. '.A.;
KORESHKOV, A.A.; KASIYAN, I.I.; KOTOVSKAYA, A.i(.; Y4LIBERD111,
G.V.; KOPANEV, V.I.; KUZIMIbOV, A.P.; KAKURIN, L.1 ; KUDROVA,
H.V.; LEBEDEV, V.I.; LEBEDEV, A.A.; LOBZI11, P.P.; MAKSIMOV,
D.G.; ~ffASNIKOV, V.I.; HAUSHKIN, Ye.G.; NEUMYVAKIN, I.P.;
ONISHCHENROY V.F.; POFOVp I.G.; PORUCHIKOV, Ye.P.; SILIVESTROV,
M.H.; SERYAPIN, A.D.; SAKSONOV, P.P.; TLHENTIYEV, V.G.; USHAKOV,
A.S.; UDALOV, Yu.F.; FOMIN, V.S.; FOMIN, A.G.; HLE8111KOV, G.F.;
YUGANOV, Ye.M.; YAZDOVSKIY, V.I.; KPICHAGIN, V.I.; AKULIVICHEV,
I.T.; SAVINICH, F.K.- .1,TMPITRA, S.F.; VOSKHZSENSKIY, O.G.;
GAMIKO) O.G., SISAUAN, N.M.,, akademik, red.
[Second group space flight and some results of the Soviet
astronauts' flights on "Vostok" ships; scientific results of
medical and biological research conducted during the second
group space flightl Vtoroi gruppovoi kosmicheskii polet i neko-
torye itagi poletov sovetskikh kosmonavtov na korabliakh
"Vostok"; nauchriye rezul1taty redikobiologicheBkikh issledovanii,
provedennykh vo vremia vtorogo gruppovogo kosmicheskogo poleta.
Moskva, Nauka, 1965. 277 p. OAIRA 18:6)

ACCFSSION NR
AUTHOR Al tukhov G. Be I a y,_ Ye e i,, o_r,),',._A
T 1 TLE 1) 1 u rn a I r 1) v t hm o v e v e t n n c o -i r, ~i u r i n i~ s a c c i
SOURCE: AN 'a SS R. I z v a s t 1 1; a , S e T 1, a b i o I u P i c h e a va , n r) 2 , 19 b')
TOPIC TAGS: diurnal rhythm. vegetative functions, rnace fli~,ht,clrdiac
rate, systolic index
ABSTRACT: Data obtained during the space flightG of Soviet co-,;rnonautg
A. G. Nikolayev, P. R. Popovich, V. 'I'. Bvkovskiy, and V. V. Tereqhkova
shed light on the effect of weightle5sncss on the diurnal rhvthi- of
physiological and, in particular , vegF LaL ive ft-;ricttons. T !I L h e e '; C n t
article , the nature of change s tri diurnal varLat Lons in pul se f re e n c y
and of the systolic index is an a I v r, d In I ~i iw T, r P. a u n c h. - ~ r
pulse f rejuencv and thp s -,,,3 1 1) r I Male C
increased dUring, thc sero!il .41 f f j -z!
c1 ine0 during the secood tial c f t~ie c4a-,t. 1- pa e
indices changed. In tile case of N i k c I a L v a ri G 0 V 1; L 0 - -j~,J
Card 112

L
ACCESSION UR: APS007274
frequency Pnd the systal t, index el r~ cr
practically unchanged durln~-. ~he v " ~i
case , the re lative inagri tu6es o e ;'.14 v~! U r n " V " ~1'1 L v L
index generally ramaineJ COnStal-,L ti,e f iisL ani sLconc;
of the day. During the second half c, " the day , T e r e 9 11 k ov a ~, p ~u s r e -
quency and systolic index dec I i n e d e ven more 'han thev 1 .1 -i j u Y I-;, -
prelaunch p e r i o d . In short, t tie d a t -t i n d, L c: a t e t h .3 t the nul ;e fT e n
and sv9tol Ic index react4ons
e e r
f I 1 '-7 e r e o t I e n t c a 'I ti e i 7-~ r r -i ~i
9 1 o I c. c. a r, z r. 9, a ri r, c C I e 5 e i
of WeLght"es3neZ5. e r t-- a ),2 e m c ~, n a e i r.
had a significant effect on these tndi--es. -z i g . ar has - .I Lau le
and 2 figures.' Bm
ASSOCIATIONi none
SUBMITTEDi 10Ju164 ENCLOSURE: 00 SUB CODE:PH ILS
NO REF SOVi 004 0 Tif E R 0111 ATD PRESS : 3-~09
Card 2 2

VA3ILIYEVp P.V,; BFLAYq V.Ye. (MoRkva)
Effect of sympathoulswtic amines on the resistance of animals
to the affect of acceleration* Pat. fiziol. I eksp, terap. 9
no.3s12-16 My-Je.165. (MIRA M9)

L 31933-66 EWT(1) SCTS DD
ACC NRs AP5017760 SOURCE CODE: UR/0216/165/000/004/0481/0490
AUTHOR: Parin"V. V..L ~V.Ye
ORG: none
TITLE: The problem of reactivity in space medicine
SOURCE: AN SSSR. Izvestiya. Seriya biologicheskaya, no. 4, 1965, 481-490
TOPIC TAGS: biologic acceleration effect, acceleration test, experiment animal, car-
diovascular system disease, centrifuge test, drug effect, biologic respiration
ABSTRACT: The use of pharmacological agents to increase the tolerance of white mice,
- 5k
rats, rabbits, and dogs to acceleration as investigated. The animals were centrifug-
ed for periods up to 86.2 min; the animals were injected (before and after centrifug-
ing) with various narcotics, cardiac glycosides, vasoconstrictors and vasodilators:
strichnine, adrenalin, noradrenalin, benzedrine, phenatrin, ephedrine, caffeine, Cora-
zol, strophanthin-K, nitroglycerine, dibazol, chloral hydrate and thiopental sodium.
The results of these injections on the various animals are presented in the form of
graphs, tables, and electrocardiograms. The criteria used to evaluate changes in reac
tion to acceleration were (in experiments on mice and rats) the number that survived
the experiment and (in the case of dogs and rabbits) the time of onset and the degree
of cardiac and respiratory malfunction. The authcrs conclude that the vise of pharma-
UDC; 629.195.2 61

L 31933-66
ACC NRs AP5017760
cological preparations is a promising means of increasing tolerance to G-forces.
Orig. art. has, 9 figurva, 1 table.
I SUB CODE; 06/ SUBM DATE- O5Jan65/ ORIG REF% 031/ OTH REF: 006 1

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All SSOC IZ'Ipstiya 07,
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trr
-7- FecktistOV; 3 B. Bi
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-lm r
YX rl
-U
MW
iii
r6thj
0141t - - -------------
'R In I
K.E 'P~ ~k t i s q'i
t4r is 21 20 1-).1.51 jg:(; 5 jo-ij
G.0 204 20-4 25-2
B. D Yegorov 1 1". IB 27 33.5 A 2
~The data showed Iffiat pulse and respiratory cl"arnics, as well as electro-

card 4/8

b 1
ej",e T-3
Card

EHF-
ACCESSION NR.- AP5017761
T -2 -from Card .5/8
-Contimation cf -able -
U -'i I' ~.' -S!,~
VIJ i4~1 i?,1.2 1.2-1.0 31.2 ~33.1 12-9.7 1 33.7 1 3G.2 123-6 JtO-9
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1R.3
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~13
Fig.- 3.11 Relatlonclup of the mean - Values ~~f-:EKG R-R. and Q-T intervals
-16ndA.-he: duretiov- of :Meebanical - SYJA
old Oii&' f cosmonauts I Various
ftace-;r1ASht-peKq.s--
B 1'~' Yeko -I,
MY.*, IWOLUI
mean --Fvae _V e i
-'e-ew Me
V

ACCESSION UR: kP5017761
fliaht. It was noted, however, that B. B. Yegorov, the f1faht physician, ex-
hibited a marked vagotonic lurimj --lie '~th orl-lit -.f
khod-l. His pulse rate decreased tc? 45- 48 beats 'min.
As a rul,,2, ET-Mt R-T! cncrfwient variationq cnincided vith respirator.-y
P1111-18es in time -,rid fendencle~~ 41rorn 7-
f
ASSOCIATFOU,
"CDE" 5v
Cnrd

L 23975-66 F8S-2/EWT(1)/EEC(k)-2/EWA(d) SW-TB TT/DD/RD/GW
ACC NRt AT6003858 SOURCE CODE: UR/2865/65/004/000/0237/0247
;AUTHOR: Yazdovskiyo V. I Yemellyanov, V8811t7eys P& Ve;
ORG: none
TITLE: Sorno results of madicobiological studies conducted during
preparation and fligbt of the astronauts V._F._B qk and V. V.
Tereahkova"
SOURCE: AN SSSR. Otdeleniye biologicbeskikb nauk. Problemy
kosmicbeskoy biologii, v- 4. 1965p 237-247
TOPIC TAGS: space medicine,, space medicine equipmentp space pbyoiologyj,
astronaut
ABSTRACT: The program of study is described and results of medicol
observations during June-14-19,, 1963 are reported. The study program
includes the long term effect of cosmic flight on the human organism,
psyenophysiologic capacities and working capacity of humans under such
conditions, reactions of the female organism, the 24 hour pbysiologic
processes during cr.,amic flight, effectiveness of methods for selecting
!
:and training astronv,.irn, -anql~~sis of tbe medical-biological monitoring
isystem in the cabin, the microclimate of the spaceship, and the

_142UZ-bb I I DD11111 UR/,
ACC NRt AT60__0_ijM6__ - SOUI=, CODE: W65
AUTHORt Kotovskaya, A. R.: VUilln,4 Pa Ve; Lapin, Be A,; Simpura, So Fe;
Shakhlamov. VO.At; Artem!ygya, N.
ORG: none
t/
TITIE: Effect of transverse accelerations on the organism of female monkeys
SOURCE i AN SSSRo Otdolenlya biologiohoskikh nauke Probleqr kosmicheskoy biologii,
v. 4, 196.5. 322-332
TOPIC TAGS: cardiovaspular system, experiment animal, biologic acceleration effect,
biologic respiration, space pbysiology, histology, biologic reproduction, space
biologic experimnt
ABSTUCT: Tests were conducted on 16 half-grown monkeys,' 5 m.Nndrill an .d
11 rhesus. -Exposure to 12 G centrifugation (varying durations) took place
during the following sex bycles: proliferation, secretion, des*quamation,
and ovulation. Acceleration took place on a centrifuge with an arm radius
of 7. 25 m In a chest-back position. The behavior of the animals was
monitored by TV. and cardiovascular and respiratory activity were used
as criteria for the resistance of animals to acceleration. A photograph
shows the position of a rnorAW fixed in the chair of the centrifuge. Table I
shows the effect of acceleration on cardiovascular and respiratory'activiV&
.01 -

ACCNR: AT6003858
!effectiveness of' systems providing for survival and safety, ln nelect-
1ing astronauts the compensatory work of the organism was nost important.!
!Under simulated cosmic conditions, wemen were seen to react least duringil
I
tthe proliferative pbase of the ovarian cycle, with qome reaction during
I
iovulation, Training increased resistance to the effect of cosmic
1factors and strengthened will power and the nouropsyebic ystem.
s
Radiation was low; the dosimeters showed about 80 and 44 millirad
respectively. The astronauts received food in amounts of 2500-2900
calories per day, The microclimate in the cabin was set;sfactorily
maintained as to temperature, pressure and oxygen (13-26 C, 250-60%
humidity, 22-28% oxygen, to 0.50% CO and 740-780 inm Hg pressure).
Medical controls included ECG, EEG, hin galvanic reaction, respiratory
and pulse rates., tests for vestibuler and vegetative insufficiency and
observation by television. Before end at the start of flight the
respiratory and pulse rates increased from 68 and 84 to 137 and 144,
during the first-minutes of flight they increased to 154 and 157) and
then they returned to normal after several hours. The EEG showed a
tendency for substitution of low frequency waves and a later decrease of
.jamplitude of-bioelectric rbytbms; in tbe-woman anlinorease of low
wavie(in, at ion .--to -weightlessness. was good*----..',.:,
it -1
t m
-d f
d 9,y- - fit ght.- r c4qla- Or: Vome
..0V1 men_
lthft~~"Vathciloklc reactions, bet's -htwu . nonev~
trBM DAM. n ne-- MAO g,
o
-Card I-M .4 ..-. I - 7 12:A -1

ACC NRt ATOULI)OM)
Table 1. Changes in pulse rate and respiration
rate in monkeys exposed to 12 G (mean for 14
animals)
Physiologl-c-a7 Before During After
function
Pulse rate 152- -fill; I! jO - .230 15f) _I wl
,Respiration N-46 AN _.'A IS 31;
rate I I
The EKGIS of animals exposed to acceleration revealed sinus tachycardia, shortened
T-P intervals, and ventricular and atrioventricular extrasystoles Cardiac activity
in general returned to normal 10-20 min after centrifugation. It was found that the
endurance of female monkeys to 32 G ranged from 1 to 4.5 min. A histological analysii
of the ovaries of monkeys examined 10 min, 1 hr, 24 hr, and 72 hr after termination ol
acceleration revealed the following deviations from normal: Proliforation phase:
Weakly pronounced depolymarization of acid mucopolysaccharided in the medulla and
separate cortical sections of the ovaries, as imll as in the uterus, Ovulation:
After one, and asPocial%V 3 days after the termination of the experiment, vU
ovarian tissues were found to be full of erythrocytes; The areas around the venules
were plasmorrhagi6 and locally hemorrhagic; Acid mucopolysaccharide depolyrorization
was intense* Seoretory phase** Two monkeys showed premature menstruation and

ACC NR: __ AT6003866
hemorrhaging in the endometrium when examined 10 min after termination.
This was attributed to the deleterious effects of acceleration. Examination
of an animal 24 hrlater revealed individual small hemorrhages in the
cortical ovarian tissue. Some erythrocytes were observed along the
vascular walls. Mdaerate depolyme-rization of arid mucopolysaccharides
was evident.
Dge!squ~mativeph:~sQ. A macro- and microscopic examination of the
ovarieg, Fallopiban lub?hs, and uterus revealed the same changes as
occurred during the proliferation phase.
It was apparent that acceleration had its greatest deleterious effect
during ovulation and its minimum effect during proliferation. The
observed deviations probably reflected neuroendocrine processes associated
with stress reactions to acceleration. The long-term effects of accel-
eration were not evident one month after acceleration, demons *trating th'e
ability of.the ovaries to regenerate after vario,4s injurtes..,orige art. has:
figures and 2 tabIes. ffM PRESS: 4091-jF
suB CCDI,;i 06 SUB~ DAM none ORIG FBF: 004 OTH REF: 006
G (!-.,
Card 14 /14

1, 232"li-66FS - 2E ~-i7r
ACC NRr AP6011411 SOURCE CODE: UR/0216/66/000100210212/0220
AUTHOR: Balakhovskiy, 1. S.; VaqLl'yev. P, VF;
Popov, I . G.,

ORG: none
TITLE: Results of a physiological and biochemical examination of the
Voskhod-1 crew
Y~_
SOURCE: AN SSSR. Izventiya. Seriya blologicheakaya, no. 2, 1966,
212-220
TOPIC TAGSt manned spaceflight, human physiology / Vookhod-1
ABSTRAM Some detailed physiological and biochemical results (in-
cluding some redundant data) of the Voskhod-l flight are given in the
following figuress
L,;_ard 17 UDCt 612,17

L 22'.81-66
-4C NR, AP6011411
11/0
Vigo 1, Comparative data on pulse variations for all coamonauto (Z
above normal) at various flight et4ges.. The sequence of bars in each
frame corresponds toi Gagarin, Titov, Nikolayev, Popovich, ]3ykovskiy#
Tereahkova, Komarov, Feoktistov, Yegorov.
I - 4 hr before launch; 2 - 5 min before launch; 3 - I min before
launch; 4 - I miu after launch; 5 - greatest G force; 6 - 1st orbit;
7 - 2nd orbit; 8 - 4th orbitj 9 - 6th orbits, 10 - last orbit#
1 2 3 4 5 6 7 8 9 10

L 2'10241-66
ACC NR, AP6011411
Table 1. Changes in some EKG indexes during the Voskhod-l flight
QRS, Q-T, R-R intervals in acc spike amplitudes of P, R. T in rciativc~
unital systolic index (SI) in i; all mean data
Card 3 7
I
Cosmonauts Indexes 1 re-
PI-aunch, Orbits

V. it. P 0185 312 2,9 0,(i 0,78
Komarev' R t511, 4913 30,5 tolo 101i
T 2 17 114,2 14,5 3,6 21(1
PQ (?,If) 0,Ij 0,ff 0,1() (?,10
QRS (),w 0,07 0.07 0,07 0,08
Q-T 0,:V, 0,37 0 38 0,38 0,14
R - if O,Ci 0,78 0:76 OIB9 0,75
S1 5517 48,7 50,7. 45.0 45.3
K, P P (),Ri 2,4 () , FAI 0,64
Feokcistov R 16,-1 - 38.7 8.9 9.1
T 3,4 - 1312 3,2 2,8
P Q 0,t4 - 0,14 0,il 0,t2
QRS 0,05 - 0,06 0,06 0,08
Q.-T 0,3r, - (1,42 0,18 0.38
R-R 0, bg 0,I)o 0,87 0,78
52,9 43,3 44,2 46.8
Be Be P 0,37 2. 1j 1'6 0,44 0,51
Yegorov I
R 10,9 32,0 19 '2 819 8,1
T 1.1 5,7 10,8 2 4 1,8
PQ 0,12 O,iz O,AG 0:0 0,t0
QRS 0,06 0,06 0,07 0.07 0,07
Q-T 0,34 0,37 0,30 0,40 037
IR -.w- 0,59 0,73 0,98 1,03 0:90
961 58,'6 50,7 40't 39,2 41,0

I'Q4
~_Aed NR_j AP6011411
Table 2. Water balance during the flight
I - Loss of water with urine; 2 - cosmonauts; 3 linen chloride
content, mg,, 4 m urine excretion, liters; 5 - water lost via imper-
ceptible perspiration during the flight, liters; 6 - totaly calcu-
lated water long through the skin during the flight, liters; 7 - water
ingested# including water in food, during the flight, liters;
8 - actual weight lost from 6:20, 12/10 to 18tlO, 13/10, 1964, kg;*
9 m V. H. Komarov, K. P. Peoktistov, B. B. Yegorov in that order.

6 7 8
3 4

532 3
4 10 4,4 1 I'V
~t9 324 2 1
: 1:0 3.1 1:6 2'"
460 3,2 1,0 4,2 1,0 3 '0
Card 4/7

ACC Ri
Table 3. Biochemical and morphological content of the blood during
the flight compared with training data
Complex-Backqwnd light
l JAIter

Indexes trainlng6amlmadm

Be - Aii--' -4 3 1 i' Iflight

"
~
foreler I days rdy. jetartl end ~.eJ day
Idayr

V. 11. Kom arov
Sugar, m�Z 92 IN - 1 105 lot - - 160 115 107

p
Urea g% 34 .38 38 22

225 251) 280 225 .12 - -7

t75 - - 'it 39 28
210 1 t35
225
Chlor
i
ne, mg%
Leukocytes, 1000[mm3 - 5.4 G, 8 5.1 4,5 4,9. - - 7,0 5.9
rormula:
Rods
51
5, 3 3 6 5 6 a

Segments 63 00,5 55,5 U 40 04 5 J

1 2
Eosinophiles
Lymphocytes 1 3,5 2 5
26 25,5 33,5 17 3
47 25 35
Monacytes 7.5 0 8
4. 5 4 0
C.ard 5 / 7

L
ACC NR, AP601141 I
K. P, Feaktistov
Sugar M
, 82 M 75 100 85 105 70 63
V
Urca,
M P.
Chlorine g %
, '0 21
Z37 25
250
1 35
Z50 25
225 31
225 -
- 47
1
200 4.)
225 - 26
Z Y-1 0

Leukocyteq, 1000/MM3 5,
5, 6
'1 5 1 5,4 4.2 5,1 5,41 6.8 4 9: -
formula;
Rods
2
415
.5
~
1
t
'
4,0
1 ,
2 -

Segments 57 c0 et
j I G's W 67
5
. 43 w N

0
E sipophiles
2
I's

b0
t
2 2
~
'
'
"1
315

Lymphocytes
32 30
27
l
o
3
8
2
5
.
3
'
5
2
1. 28 5
Monocytea 7 4 8 4 9 4,5 f0 815

B. B. Yeg orov
Sugar, me%
SO Ito 115 its 76 112 55 65 59

Urea, mg/* .10
1
2 10 19

280 33
1
220 23

260 -

220 51

210 41

W 40

220 41

2AO 38

200
Chlorine m g% 3
100( mm
Leukocytes, If's 6,5 8.0 8,1. - f8j 12,0 8,2 -
Formula:
2
3

,5
1
3
-
0.5,
1 5
2,5
Rods
.90~~ pDra _53
j 5
3
~ Si
~2_5 55
1 43
4 -
- 35,5'
25 62.5
t 51.5
2,5 -
-
L f it 7 B

'it Vas U-,6,LTa%\ xNm', k!wz, t%,at taterate ra-entry au rfell abT
they did ceatrie"Igatica during tralaIng, ThIa WDO attribUted tO the
day-long axposuTa to veiglhtleasnaza. Uone of the observed deviations

-232BI-66-
L
ACC NR; AP6011411
from normal was pathological and rapid recovery took place. Attention
is brought to the individual somatic and autonomic peculiarities of
the cosmonauts and their level of traininR- Orig. art. has% 4 ables
.and 2 figa. JCD]i
SUB CODE: 06/ SUBM DATE: IOSep65/ ORIG REFs 010/ OTH REFJ 00
ATI) PRESS., 12
Card* 7 17 ukj~

L
ACC NRi X160.361,72 -SOURCE COON., U1'J0000/66/000/000/00Ir,/00j9
AUTHORI Alculinichey,j, T.; Bnykovt Y'as,
Rikalmov, Do.G.; UgIovp__~, Yes Chokhonndaltlyt NvAs
ORGt none
TITLE: Some data,from elec trophysiological Investigations conducted on the crev
of the -Oskhod-2'during spaceflight (Paper presented at the Conference on Problem
e'-~ I
of SP c iR-na hold in tbscow from 24-27 May 1966)
SOURCE: Monforwitslya po problemam kosmicheskoy meditsinyo 1966.'Problemy
kosmichoslcoy medItsIny. (Froblems of space medicine); materialy konferentallp
lbscow, 1966, 18-19
TOPIC TAGSt space phystologyp manned space flight, Loonovo extravehicular
activity, cardiology, cardiovascular system, electrooculogram, electrocardiogram#
body temperaturep eloctraphysiologyp respiration# heart rate Voskhod-2
ABSTRACT:
Ele'ctrocardio~rams,'pndiimograms, seismocardiograms, and
,electro-oculograms were registered on the Voskhod-2 cosmonauts,
Belyayev and Leonov. In addition, Leonov' s body temperature was
measured. After the spaceship attained orbit, the frequency of cardiac
contractions continued to.increase and to exceed the levels registered

L 08276-67- -
ACC NR& AT60361,72
'during active acceleraticn. These changes in pulse rate were due to the
preparations for Leonovi a EVA. During EVA, their heart rates A
reached the maximums of 129 and 162 beats/min. By the third orbit,
the heart rate and respiration frequencies of the two cosmonauts becanle'~!
normal, equaling prelaunch magnitude. Further chahges were com-
parable to those noted in preceding flights. The lowest heart rates were,-
recorded during the seventh orbit. From the thirteenth to the eighteenth
orbIt there was a gradual increase in the rate of cardiac contractions
(86-~lll) and an increase in respiration rate up to 18-20 cycles/min, J
which was related to the performance of a series of tasks according
'to the program, and to..the- emotional. strain induced Lfy preparation-for
manual re-entry.
Analysis of the EKG indicated.that thL- significance of tile Q-'T and'-"--I
R-R intervals in both cosmonauts corresponded to changes in frequency
of the heart rate. The lability of the Q-T coefficient waii higher at the
be&ning and end of the flight in both cosmonauts and diminished noticeably
-during the middle of the flight. The same was observed in relation to the
Amplitude of tile E KG peaks. The duration of the mechanical systole in
Igeneral followed changes in pulse rate from the third to the sixteenth
orbit; the duration of LeonovI s mechaniual systole varied from 0. 32-0. 35 -
213

L--08276-67-
ACd NRs AT60)6472 0
I
sec. During the-17th and 18th orbits, the'duration .of the mechanical
systole diminished to 0. 29-0. 27 see simultaneously with an increase in
the pulse rate. Electromechanical lag was determined only in Leonov
during various times of the flight varied from 0. 02-0. 06 sec.
Oculomotor activity during the first two orbits rose in both cosmonauts
Ao 105-111 movements/min. During the third and fourth orbits the number
'or6culomotor reactions diminished and after that varied within relatively
low limits: 10-10 movements/min. The dyn~tniics of the viectro-oculo--ram.
corresponded to.changes n the pulse and respiration frequency and
reflected, apparently, the general condition of the cosmonauts. An
analysis of the amplitudes and the curve of the EOG indicated that eye
movements in the cosmonauts were rather symmetrical during the entire
duration of the flight. *~".'-I " ..I" ,
LeonovI s armpit temperature varied during the flight from 35-37. 60'C.
The higher temperatures were recorded during the 2nd, 16th, and the
17th orbits. This can be explained by emotional. strain-and. performance
of r)hys,cal taskA_~~the_ cosmonaut., LrW. A. No. 22; ATI) Roport 66-1161
'SUB CODE: 06,2Z / SUBM DAM OOMayO
Card 3/3 vmb

ACC NRs AT6036518 SOURCE CODBt UR166661alOot)1000100961097
AUTHOa: Vasil'yov, P. V.; Iysukh:Lna, G, V',; Uglovat N. N.
ORG: ' none
TITLE: Increasing the resistance of animals to transverse accelerations Iry means
of active and pausivo acclimatitation under alpine conditions ff-apor presented at
the Conforanco on Problems of Space Modicino hold in I'll'oscow from 24 to 27 Vay 1966.7
SOMPICE: Konferontsiya po, problemam kosmichoskoy wditsiny, 1~66e ProblevV kosrachos-I
Icoy rioditsiny* (Problems of space medicine); matorialy konforontsii, Moscow, 1966,
96-97
.LoPIC TAGS: high altitude physioloey, hypoxia, alpino acclimtizations cosmonaut
training, biologic acceleration effect, acceleration tolerance
ABSIMAGT: The efficacy of passive and active (with physical exercise) alpino accli-
matization as a nonspecific training method of increasing adaptive capacity to several
o.%&.romal spaceflight factors, espocially accolorations. was studied in 461 mice, 95
rats, and 28 guinea pigs acclimatized to alpine conditions in the neighboehood of
Mt. Ellbrus. Functional state of the animals was evaluated before, during, and
after acclinitization from blood analyses, gas metabolism determinations! and body
weight dynamics.
Card 1/2

---At6d365i8~__-_______
-AcCWRI
Acceleration tolerance in mice was determined by comparing survival
rates for experimental and control groups of animals. In rats and guinea
pigs, tolerance to acceleration was based on onset tirm and severity of car-
diovascular disturbances shown on BKG' s.
It was found that survival of acclimatized animals exposed to large ac-
celerations was 1. 5 to 2 times higher than that of the controls, this effect
persisting 3 to 4 weeks after acclimatization ended. Cardiac disturbances
appeared later and were less severe in acclimatized:animals.
Active alpine adaptationWith systematic physical training was more ef-
fective than passive exposure to high altitude. Active alpine acclimatization
produced an acceleration survival rate 107o to 25%o higher than passive ac-
climatization. bf. it. No* 22; ATD Report~66-1167
SUB com.;: o6 / SUBM DATE: OOMay66

;kc-c- N-Ri-A-F-6-033399 souRcE com uR/o2q3/66/O04/005/0T55/0T6T
6 7' '. .
AUDIOR: Vqlpkin_, Yu. M ; Akulinichev, I. T.;
A. D.; Kaslyan, I. I.; Maksimov, D. G.
ORG: none
TITLE: Some data on the condition of cosmonauts during the flight of the Vookhod-1
spacecraft
S(XJRCE: Kosmicheskiye issledoyaniya, v. 4 no. 5, 1966, 755-767
TOPIC TAGS: space physiology, space ~dc Ae, human physiology, cjadiovaocular
system, nervous system, vestibular analyzer/Voskhod 1
ABSTRAM A diagram of the biomedical monitoring parameters and some results of a
further statistical analysis of the Voskhod-1 flight are presented in the following
figures and tables. As in other discussions of this flight, the general conclusion-
was that none of the observed.physiological shifts were of a pathological nature, and
therefore, were reversible. The most significant finding of the flight was a con-
fix-mation, of the possible. specific effect of weightlesaness an the statokinetic

ACC NRs APb033399
PG +.-SCG Fig. 1. Block diagram of physiologiml
K parameters recorded during the flight
of Voskhod-l
RTS TS Photo
ecor e EKG - Electrocardiogram; PG, SCG -
pneumogram plus seismocardiogram;
VISM
On EEG - electroencephalogram; PECP -
EKG DS. pulmoelectrocardiophone-, EOG - elec-
trooculogram, XT - coordination t,--st;
KO - kinetogram-, RM - rediotelemetry
order;~'
Rec eystem; DS-Mir-2 - data stoirage 4nit;
AR vaplIfier-readout#
'lectro
oefffol
o
6 ffr, 0
inzi.
ionsors
W
Cwd '21fi

ACC - N-Rt AP603j799
verore tito
Physiological S.Z I.X
Cosmonauts JI.X
r 'I'
index. Fh
Pr ej,
_rq64__ L I
at, 151
ay Oay

V. M. Komaro1v Pulse
R 76
a 68
12 72
1 Or 89 69 80 65 i
;
tion
;= 0 18 23 20 11 1 C)
A
pres-.. 116 115 120 115 M
wire
75
- 70 71-
6
-
-
-
-0
13
:K. A &cktisto6 Pul3c 80 84 80 78 86 97 84 72
Respiration 12 16 18 21 20 21 16 11
Arterial,, pres- 110 105 125 Jos 115
sure
-85
B. B. Yegorov Pulse ' '
72 .64 64 81 86 05 84 68
Respiration 14 14 14 18 26 21 10 15-
Arterial pres- IQQ 105 120 - 120 110
sure
Table 1. Dynamics of the pulse rate, respiration rate, and,
arlterial pressure of the Vockhod-1 cosmonauts before, durirg,,
and after the flight (from the data of M. D. Nikitin et al).
Card

ACC NRs AP6033399

r
IN -

91 0
0 2
-3

0 Ozz -
#Y
2
I
Ozo
'd - A 3 i IV -
k
e
i_
jw
>
-VI
w
4 hr'
*
a;a10 . I min pre Orbitd
landing
1 day 4 hr z 7 Ij to ffm Jaunch _
~. mirk pre- -Oirbits,
launch
Fig. 2. Dynamics of the average respiratory Fig. 3. Dynamics of the average P=ulse_~
rates of V. M. Komarov (2). k. P. Yeoktistoy rates of B. B. Yegorov (1), V. M.
(3), and B. B. Yegorov. .(1) before, during, (2), and K. P. Feoktintov (3), before,
and after tbe-Soiihod-1 flight during, and after the Vookbod-I flight

-
- --- -
rACC
Nes AP60
33399
2.5 hx j Orbits
Parameters. -Cosmonauts be fol
~
jii~n
c H Is i9

V, .M.'-K IomArov 0.12 0,10 0.11 0,10 0,12 0.11 0.11 0'.11 0.10 0.10 0.10 0.10
Bec K, P. FeoI(tist0v 0.15 0.14 - 0.13 0.16 0.13 0.16 0.14 0,11 0.12 0,12 0.12
]3.1 1), YegoroV., 0.12 0.12 0.12 -0,13 0.13 0.14 0.14 0.16 0,10 0.12 -- 0,10

M., KOIDULrov 0,34 q.34 0, 3? 0,34 0,37 0,38 0.35 0.38 0,39 0.36 0,34 0,34

aec
K N Feoktiatov 0,36 0.36 - 0,30 0.37, 0.37 0.37 0.42 0.38 0.39 0.31 0,36
'
B Yegorov. 0.33 0.34 0.37 0.38 0.39 0.41 0.44 0.39 0.40 0.36 - 0,37
0.69 0,61 0.78 0,70 0, Oa 0.99 0,61 0.76 O.S9 0,71 0,72 0,76
Yd M.,. Itomardv
~ 0.16 0.69 - 0.82 0.86 0.91 0.90 .
0.96 0,81 0.62 O,W 0,76
K. P;, Feoktils.tov
,R-R, aec 0.61 0,69 0.73 0.86 0,96 1113 1,24 0,66 1,03 0,81 *r 0.90

49,9 57.7 4k 7 51.7 43.7 40.0 58,2 30,1 45.0 51.1 47,2 45,3
Komaro4.. 47,6 62,9 _- 44,6 42,4 40,0 41.3 43.3 44,2 47.9 4%6 46.3
C4 49,2 58.6 60.1 43.4 39,1 36,2 X.8 40.1 39,2 44,2 - 41.0.
.
Table 2. Some indices of the cardiac activity of V M. Komjirov (1) , K. P. Feoktista
(2), and B. B. Yegoroy (3) be fore and during the flight of Voskhod-I
77"

399
V.- M. Komar V K. P. _Fe_oktjjtovjB. B. Yegorov
-orbits TM-1. sec
MIS C, % JWsec sel C. IA I Msec sec C, %
5 min
bef ore 0.68 0,07 10.6 0,72 0.076 10,56 0.70 0.013 10.50, .
1 0.72 0.08 12,8 0.75 0,031 4,16 0,69 0,074 10,14
3 0.51 0.008 11.26 0,84 0,084 9,96 0"" 0, IOD 11.55
6 0.62 0,076 9,14 0,66 0,074 1.66 1'31 0.044 3.36-
13 0,87 0.038 4,34 0,93 0,091 9,80 1,02 06067 6,58
16 0,74 0,043 6,82 0,81 0,053 6150 0.96 0.062 61,60
Table 3. Results of astatistical analysis of R-R intervals
for V. M. Komarov (1), K. P. Feoktistoy (2), and B. B. Yegoroy
(3) before and during the Voskhod-l flight
analyzer and its interaction with other analyzers leading to the possible development
of prolonged spatial disorientation illusions and prolonged vestibuloautanomic reac-
tions which decrease the work capacity of cosmonauts. Orig. art. has: 4 figures
and 4 tables.
6M COLE: 061 SUBM DATE: 26mEw661 oRi(; REF: 010/ MR MY: 001/ ATD PRESS: 51W

ACC NR-- AT7011641 SOURCE; CON'. U1(/0000/66/000/000/0001/0018
AUTHOR: BclaY5 V- Ye-; V.1511'YOV P V ; Glod, G. D.
ORG: none
TITLE: PharmacoloSy and rianned spacofli."ht
SOU'RCE: Internntional Astronautical Congress. 17th, Madrid, 1966. Doklady.
no. 3. 1966. Problena farnakolo-ft v kom-iiicheskoy meditsino, 1-18
V
TOPIC TAGS: space pharmacologyi antinccoleration drug, altered biologic
reactivityi weightlessness, b1olo.-ic acceleration offect, antimotion sickness drug,
antiradiation drug
ABSTRACT:
The authors feel that pharmacological preparations
can be used to advantage in enabling man'to withstand
the effects of certain spaceflight factors. While anti-
acceleration drugs need nqt be used'during launch into
.()rbit, it is felt that after t1lo or more weeks of weight-
le8sness they may become important on reentry. Phena-
mine, strychninep and securine appear to be the most
promising antiacceleration drugs. For countering the
effects of-weiglitlessness, phenamine, caffeine, stryeh-
.nine, securine, ginseng, and 13lentherococcus have
been found useful. For.countering the effects of irolion
CeIrd 1/ 3

ACC NR: AT7011641
sickness, pentasen (merpanit), ainima.zine, and meta-
mizil (2-(diethylamino benzilate vdrochloride) are
suggested.
Antiradiation drug's are considered a special pro-
blem due to presence of other spaceflight factors.
At present Liriej are using cysteamine, cystamine, TT,
and serotonin. However, while these'drugs are effective
antiradiation agents they happen to reduce resistance
to acceleration stress and vibration. Consequently,
substances will have to be found.which will reduce the
unfav-.rable effects of antiradiAtion drugs on accelera-
.tion and vibration tolerance befor-z an effective phar-
macological antiradiation system. can be developed for
:spaceflight purposes.
Studies have been made indicating that exposure to
different spaceflight factors 'affects the reactivity
of the organism to various drugs. Thus, acceleration
increases sensitivity to cardiac glucosides (K-stro-
phanthin, convasid) and narcotics (barbituates, ether,
chloral hydiMte) but reduces sensItivity to certain ana-
leptics (caffeine, corazol, cytisine). Reactions of the
Card 2/3

ACC Nil; A-001164 I
ore,anism to adrenalin are interesting because they
tend to change with the intensity and magnitude of
acceleration stress. Hypoxia also affects the or-
ganism's reaction to radiation and tends to increase
sensitivity to cardiac L;lucosides and certain pharma-
cological substances.
Consequently the tasks of space pharmacology should
be: 1 - to search for drugs. capable of increasing the
stability of an organism to the unfavorable efrect of
spaceflight factors; 2 to study the effect of indi-
vidual and combined spaceflight factors on reactions
of the organism to various drugs; 3 - to -develop
dosimetry and methods of Introduction of drugs under
.,s as indi-
apaceflight conditions; 4 - to utilize drug
cators of phyoiological functions for the purpose of
clarifying the effects of.spacefliglit on the organism.
Orig. art. has: 3 figures and 1 tablo. 'EATD PRESS: - 5098-JF
SUB CODE: 06 / SUBM DATE: nano ; ORIG RFF: 047/ OTH REF: 023
Card 3/3

ACC NR, AP7005701 SOURCE CODE: UR/0216 /6-1/ooo/001/01o4/0115
i
,.AUTHOR: Kaslyan, I.I.; Vasil1yev._P..V.; MakBimov, D.G.; Akulinichev,
I.T.; Uglov, I
A.Ye.; Baykov, Ye.; Chekli6nadskiy, N. A.
.ORG: none
jTITLE: Some cardiovascular and respiratory system reactions of the
I
icosmonauts during the orbital flight of the Voskhod-2 spacecrafL
ISOURCE: AN SSSR. Izvestiya. Seriya biologicheakaya, no 1, 1967,
1104-115
';TOPIC TAGS: weightlessness, cardiovascular system, respiratory system,
electrocardiography, psychologic stress, jl',,9 C P- PR Y %Y1 04 0 6 L/
ABSTRACT:
Cardiovascular and respiratory system data for A. A. Leonov and P. I.
Belyayev mnitored during the March 16, 1965 Vaskhod-2 spacecraft flight
and extravehicular excursion is analyzed. The significance of the R-R,
PQ, QT and QRS intervals and the P, R, S and T-waves of the EKG's was
determined. Pulse rate, respiration frequency, and systolic indax were
.found on the basis of pneumogram data. The EKG and pneumogram data were
mathematically processed for each orbit., Findings show that under conditions
of.:~~i,_Otlessness. the general condition of the cosmonauts wao not parked
Card ilDr-612-L52-3

ACC NRi AP7005701
by any si gni f ican-t.disorders with the exception of someIfunctional shifts
'in the cardiovascular system: marked reduction of heart contraction
frequency, sometimes lower than initial values; more marked fluctuation oz
time intervals and amplitudes of EKG waves; and, in the case of P. I.
Belyayev, the preserice of ventricular extrasystoles. Analysis of the
respiratory cycle phases and their coefficients of variation indicates
relative stability of respiratory functions: Postflight medical examina-
-tions did no.t. disclose any significant functional system shifts. Pulse J
crate increases by 12 to-f6 beats/min, systolic arterial -pressur-e increagis--
by 10 to 15 mm Hg, and the diastolic pressure remained practically the
same. Respiration-frequencies corresponded to initial values. The most
pronounced cardiovascular and respiratory reactions were displayed by
Belyayev during the second orbit when his companion returned to the space-
craft and during the seventeenth orbit when he operated the controls
manually. The highest reactions displayed by Leonov were during the second
orbit at the time of his extravehicular excursion and return to the space- I
craft. These shifts are attributed to the emotional strain involved in
performing the most difficult tasks of the flight mission. The medical
data show that the orbital flight and extravehicular excursion did not
:produce any sharp changes in the basic functional system and did not
reduce the work capacities of the cosmonaurs._~Nllg. pLrt,_ _has:
figures and 1 iable*." 1063
!SUE CODE: o61 SUBM DATE:. 26Apr661 oRiG REv: oo6/ OTH REF: 003/
ATD PRESS: 5116

."Van.
W-3 MR= -MIMI
EWT(d)/rF-S$-2/EECi k)-2/EWP(l IJP(c) BB/GG
L 8181-0
U IP5028142 SOMWE COM UR/0106/65/000/011/0046/0054
iAUTHCRI Vasillyev" P. V. qqj~~"
MOt none
TITLEs Optinal code-combination length for feedback signals In RQ data-trarAidasion
systems
iSOMOBt Blektrosvyazl, no. 11, 19.65, 48-54
I Sr
/6c ql,
iTOPIC TAGS% data processin )data transmission
ABSTRACTs A formula is developed for the length of code combination that conveys
:automa.
tic-request-for-repetition (ARQ) signals; this length onsures maximum
iefficiency of transmission in ARQ-equipped systems; a binomial error distribution
An both forward and reverse channels Is assumed. The system has no storage and
!pei~mits unlimited number of ARQ'B. It is found that the data-tranBmission efficienor
1(a) largely depends on the length of the code combination used in the ARQ c~iannel
4nd (b) has a pronounced maximum. The position of this maximum is practically
Andependent of the length of the coded unit transmitted over the forward channel.
Higher fidelity of information transmission over the forward channel requires
Monger code combinations in the reverse channel. Orig. art. has,t 4 figures,
132 f0 I table. UDC.-621-391.151
M MA
41 Ift o9 I SM DATEs Mar6S MM REVs 002 / OTH REY% 004
Lcq4 VOUB CODE: IT,

VAST-LIEV,
Economic status a.-O organization of labor; based on mawrials, ~..f forest and
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JIF55V . v~>'
1. -Personnel manaGement.
2. I'abor product--vity-russia
3. Wages-dussla.

VA~ 1; M VasWevich-
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Izd-vo Andemil raul, SSSh. 19148. e6 t!. (Its 'liudy) (49-52269)
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